PubMed:1899335 JSONTXT

{"project":"PMID_GLOBAL","denotations":[{"id":"T1","span":{"begin":333,"end":336},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":475,"end":478},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0016692"},{"id":"A2","pred":"mondo_id","subj":"T1","obj":"0018687"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0016692"},{"id":"A4","pred":"mondo_id","subj":"T3","obj":"0018687"}],"text":"Expression of c-jun, jun B and jun D proto-oncogenes in human peripheral-blood granulocytes.\nWe have found that purified human peripheral-blood granulocytes express constitutively significant levels of proto-oncogenes c-jun, jun B and jun D mRNA. Upon functional activation of granulocytes by 4 beta-phorbol 12-myristate 13-acetate (PMA), the levels of c-jun, jun B and jun D transcripts were increased. The three jun genes showed a similar time course in their induction by PMA, maximal mRNA levels being reached after 60 min of induction. These results suggest that expression of c-jun, jun B and jun D genes might be involved in terminal granulocyte differentiation or in regulating granulocyte functionality."}

{"project":"jnlpba-st-training","denotations":[{"id":"T1","span":{"begin":14,"end":52},"obj":"DNA"},{"id":"T2","span":{"begin":56,"end":91},"obj":"cell_type"},{"id":"T3","span":{"begin":112,"end":156},"obj":"cell_type"},{"id":"T4","span":{"begin":202,"end":217},"obj":"DNA"},{"id":"T5","span":{"begin":218,"end":245},"obj":"RNA"},{"id":"T6","span":{"begin":277,"end":289},"obj":"cell_type"},{"id":"T7","span":{"begin":353,"end":387},"obj":"RNA"},{"id":"T8","span":{"begin":414,"end":423},"obj":"DNA"},{"id":"T9","span":{"begin":582,"end":587},"obj":"DNA"},{"id":"T10","span":{"begin":589,"end":594},"obj":"DNA"},{"id":"T11","span":{"begin":599,"end":610},"obj":"DNA"},{"id":"T12","span":{"begin":632,"end":652},"obj":"cell_type"},{"id":"T13","span":{"begin":686,"end":697},"obj":"cell_type"}],"text":"Expression of c-jun, jun B and jun D proto-oncogenes in human peripheral-blood granulocytes.\nWe have found that purified human peripheral-blood granulocytes express constitutively significant levels of proto-oncogenes c-jun, jun B and jun D mRNA. Upon functional activation of granulocytes by 4 beta-phorbol 12-myristate 13-acetate (PMA), the levels of c-jun, jun B and jun D transcripts were increased. The three jun genes showed a similar time course in their induction by PMA, maximal mRNA levels being reached after 60 min of induction. These results suggest that expression of c-jun, jun B and jun D genes might be involved in terminal granulocyte differentiation or in regulating granulocyte functionality."}

{"project":"pubmed-sentences-benchmark","denotations":[{"id":"S1","span":{"begin":0,"end":92},"obj":"Sentence"},{"id":"S2","span":{"begin":93,"end":246},"obj":"Sentence"},{"id":"S3","span":{"begin":247,"end":403},"obj":"Sentence"},{"id":"S4","span":{"begin":404,"end":540},"obj":"Sentence"},{"id":"S5","span":{"begin":541,"end":712},"obj":"Sentence"}],"text":"Expression of c-jun, jun B and jun D proto-oncogenes in human peripheral-blood granulocytes.\nWe have found that purified human peripheral-blood granulocytes express constitutively significant levels of proto-oncogenes c-jun, jun B and jun D mRNA. Upon functional activation of granulocytes by 4 beta-phorbol 12-myristate 13-acetate (PMA), the levels of c-jun, jun B and jun D transcripts were increased. The three jun genes showed a similar time course in their induction by PMA, maximal mRNA levels being reached after 60 min of induction. These results suggest that expression of c-jun, jun B and jun D genes might be involved in terminal granulocyte differentiation or in regulating granulocyte functionality."}

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{"project":"GENIAcorpus","denotations":[{"id":"T1","span":{"begin":14,"end":19},"obj":"DNA_domain_or_region"},{"id":"T2","span":{"begin":21,"end":26},"obj":"DNA_domain_or_region"},{"id":"T3","span":{"begin":31,"end":52},"obj":"DNA_family_or_group"},{"id":"T4","span":{"begin":56,"end":78},"obj":"cell_type"},{"id":"T5","span":{"begin":79,"end":91},"obj":"cell_type"},{"id":"T6","span":{"begin":112,"end":143},"obj":"cell_type"},{"id":"T7","span":{"begin":144,"end":156},"obj":"cell_type"},{"id":"T8","span":{"begin":202,"end":217},"obj":"DNA_family_or_group"},{"id":"T9","span":{"begin":277,"end":289},"obj":"cell_type"},{"id":"T10","span":{"begin":293,"end":331},"obj":"other_organic_compound"},{"id":"T11","span":{"begin":333,"end":336},"obj":"other_organic_compound"},{"id":"T12","span":{"begin":414,"end":423},"obj":"DNA_domain_or_region"},{"id":"T13","span":{"begin":475,"end":478},"obj":"other_organic_compound"},{"id":"T14","span":{"begin":480,"end":499},"obj":"other_name"},{"id":"T15","span":{"begin":582,"end":587},"obj":"DNA_domain_or_region"},{"id":"T16","span":{"begin":589,"end":594},"obj":"DNA_domain_or_region"},{"id":"T17","span":{"begin":599,"end":610},"obj":"DNA_domain_or_region"},{"id":"T18","span":{"begin":632,"end":652},"obj":"cell_type"},{"id":"T19","span":{"begin":686,"end":697},"obj":"cell_type"}],"text":"Expression of c-jun, jun B and jun D proto-oncogenes in human peripheral-blood granulocytes.\nWe have found that purified human peripheral-blood granulocytes express constitutively significant levels of proto-oncogenes c-jun, jun B and jun D mRNA. Upon functional activation of granulocytes by 4 beta-phorbol 12-myristate 13-acetate (PMA), the levels of c-jun, jun B and jun D transcripts were increased. The three jun genes showed a similar time course in their induction by PMA, maximal mRNA levels being reached after 60 min of induction. These results suggest that expression of c-jun, jun B and jun D genes might be involved in terminal granulocyte differentiation or in regulating granulocyte functionality."}