PubMed:18674790 / 1181-1744 JSONTXT

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LitCoin-sentences

Id Subject Object Predicate Lexical cue
T8 0-563 Sentence denotes Mechanistic studies revealed that OB rats are sensitized due to: (1) higher oxyradical stress leading to upregulation of uncoupling proteins 2 and 3, (2) downregulation of cardiac peroxisome proliferators activated receptor-alpha, (3) decreased plasma adiponectin levels, (4) decreased cardiac fatty-acid oxidation (666.9+/-14.0 nmol/min/g heart in ND versus 400.2+/-11.8 nmol/min/g heart in OB), (5) decreased mitochondrial AMP-alpha2 protein kinase, and (6) 86% drop in cardiac ATP levels accompanied by decreased ATP/ADP ratio after doxorubicin administration.

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T10 37-41 OrganismTaxon denotes rats NCBItxid:10118|NCBItxid:10116|NCBItxid:10114

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
5413 34-36 DiseaseOrPhenotypicFeature denotes OB MESH:D009765
5414 37-41 OrganismTaxon denotes rats NCBITaxon:10116
5415 121-148 GeneOrGeneProduct denotes uncoupling proteins 2 and 3 NCBIGene:25708|NCBIGene:54315
5416 180-229 GeneOrGeneProduct denotes peroxisome proliferators activated receptor-alpha NCBIGene:25747
5417 252-263 GeneOrGeneProduct denotes adiponectin NCBIGene:246253
5418 294-304 ChemicalEntity denotes fatty-acid MESH:D005227
5419 392-394 DiseaseOrPhenotypicFeature denotes OB MESH:D009765
5420 425-450 GeneOrGeneProduct denotes AMP-alpha2 protein kinase NCBIGene:65248
5421 480-483 ChemicalEntity denotes ATP MESH:D000255
5422 516-519 ChemicalEntity denotes ATP MESH:D000255
5423 520-523 ChemicalEntity denotes ADP MESH:D000244
5424 536-547 ChemicalEntity denotes doxorubicin MESH:D004317

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T11 34-36 GeneOrGeneProduct denotes OB
T12 121-142 GeneOrGeneProduct denotes uncoupling proteins 2
T13 215-223 GeneOrGeneProduct denotes receptor
T14 224-229 GeneOrGeneProduct denotes alpha
T15 252-263 GeneOrGeneProduct denotes adiponectin
T16 300-304 GeneOrGeneProduct denotes acid
T17 334-339 GeneOrGeneProduct denotes min/g
T18 340-345 GeneOrGeneProduct denotes heart
T19 377-382 GeneOrGeneProduct denotes min/g
T20 383-388 GeneOrGeneProduct denotes heart
T21 392-394 GeneOrGeneProduct denotes OB
T22 411-424 GeneOrGeneProduct denotes mitochondrial
T23 429-435 GeneOrGeneProduct denotes alpha2
T24 436-450 GeneOrGeneProduct denotes protein kinase
T25 464-468 GeneOrGeneProduct denotes drop

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T24 34-36 GeneOrGeneProduct denotes OB
T25 61-68 GeneOrGeneProduct denotes to: (1)
T26 121-142 GeneOrGeneProduct denotes uncoupling proteins 2
T27 215-223 GeneOrGeneProduct denotes receptor
T28 224-229 GeneOrGeneProduct denotes alpha
T29 252-263 GeneOrGeneProduct denotes adiponectin
T30 294-299 GeneOrGeneProduct denotes fatty
T31 300-304 GeneOrGeneProduct denotes acid
T32 334-339 GeneOrGeneProduct denotes min/g
T33 340-345 GeneOrGeneProduct denotes heart
T34 377-382 GeneOrGeneProduct denotes min/g
T35 383-388 GeneOrGeneProduct denotes heart
T36 392-394 GeneOrGeneProduct denotes OB
T37 411-424 GeneOrGeneProduct denotes mitochondrial
T38 425-428 GeneOrGeneProduct denotes AMP
T39 429-435 GeneOrGeneProduct denotes alpha2
T40 436-450 GeneOrGeneProduct denotes protein kinase
T41 464-468 GeneOrGeneProduct denotes drop
T42 480-483 GeneOrGeneProduct denotes ATP
T43 516-519 GeneOrGeneProduct denotes ATP
T44 520-523 GeneOrGeneProduct denotes ADP

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T13 34-36 DiseaseOrPhenotypicFeature denotes OB DISEASE
T14 392-394 DiseaseOrPhenotypicFeature denotes OB DISEASE

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T3 121-142 GeneOrGeneProduct denotes uncoupling proteins 2
T4 180-223 GeneOrGeneProduct denotes peroxisome proliferators activated receptor
T5 224-229 GeneOrGeneProduct denotes alpha
T6 252-263 GeneOrGeneProduct denotes adiponectin
T7 429-435 GeneOrGeneProduct denotes alpha2
T8 464-468 GeneOrGeneProduct denotes drop

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T6 349-351 DiseaseOrPhenotypicFeature denotes ND 0010691

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T13 34-36 DiseaseOrPhenotypicFeature denotes OB DISEASE
T14 392-394 DiseaseOrPhenotypicFeature denotes OB DISEASE

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T13 34-36 DiseaseOrPhenotypicFeature denotes OB DISEASE
T14 392-394 DiseaseOrPhenotypicFeature denotes OB DISEASE

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T27 252-263 ChemicalEntity denotes adiponectin http://purl.obolibrary.org/obo/CHEBI_81572
T28 425-428 ChemicalEntity denotes AMP http://purl.obolibrary.org/obo/CHEBI_456215|http://purl.obolibrary.org/obo/CHEBI_28971|http://purl.obolibrary.org/obo/CHEBI_16027
T31 480-483 ChemicalEntity denotes ATP http://purl.obolibrary.org/obo/CHEBI_30616|http://purl.obolibrary.org/obo/CHEBI_15422
T33 516-519 ChemicalEntity denotes ATP http://purl.obolibrary.org/obo/CHEBI_30616|http://purl.obolibrary.org/obo/CHEBI_15422
T35 520-523 ChemicalEntity denotes ADP http://purl.obolibrary.org/obo/CHEBI_73342|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_16761
T38 536-547 ChemicalEntity denotes doxorubicin D004317|http://purl.obolibrary.org/obo/CHEBI_64816|http://purl.obolibrary.org/obo/CHEBI_28748

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T5 37-41 OrganismTaxon denotes rats

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T38 536-547 ChemicalEntity denotes doxorubicin http://purl.obolibrary.org/obo/CHEBI_28748|http://purl.obolibrary.org/obo/CHEBI_64816|D004317
T35 520-523 ChemicalEntity denotes ADP http://purl.obolibrary.org/obo/CHEBI_16761|http://purl.obolibrary.org/obo/CHEBI_456216|http://purl.obolibrary.org/obo/CHEBI_73342
T33 516-519 ChemicalEntity denotes ATP http://purl.obolibrary.org/obo/CHEBI_15422|http://purl.obolibrary.org/obo/CHEBI_30616
T31 480-483 ChemicalEntity denotes ATP http://purl.obolibrary.org/obo/CHEBI_15422|http://purl.obolibrary.org/obo/CHEBI_30616
T28 425-428 ChemicalEntity denotes AMP http://purl.obolibrary.org/obo/CHEBI_16027|http://purl.obolibrary.org/obo/CHEBI_28971|http://purl.obolibrary.org/obo/CHEBI_456215
T27 252-263 ChemicalEntity denotes adiponectin http://purl.obolibrary.org/obo/CHEBI_81572
T70269 464-468 GeneOrGeneProduct denotes drop
T37019 429-435 GeneOrGeneProduct denotes alpha2
T6 252-263 GeneOrGeneProduct denotes adiponectin
T5 224-229 GeneOrGeneProduct denotes alpha
T35860 180-223 GeneOrGeneProduct denotes peroxisome proliferators activated receptor
T3 121-142 GeneOrGeneProduct denotes uncoupling proteins 2
T14 392-394 DiseaseOrPhenotypicFeature denotes OB DISEASE
T43014 34-36 DiseaseOrPhenotypicFeature denotes OB DISEASE
T41232 37-41 OrganismTaxon denotes rats