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PubMed:1851858 JSONTXT

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PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 96-118 DiseaseOrPhenotypicFeature denotes oral hairy leukoplakia 0000743
T2 510-532 DiseaseOrPhenotypicFeature denotes oral hairy leukoplakia 0000743
T3 537-541 DiseaseOrPhenotypicFeature denotes AIDS 0012268
T4 1155-1177 DiseaseOrPhenotypicFeature denotes oral hairy leukoplakia 0000743

DisGeNET

Id Subject Object Predicate Lexical cue
T0 70-92 gene:1385 denotes transactivator protein
T1 96-118 disease:C0206186 denotes oral hairy leukoplakia
R1 T0 T1 associated_with transactivator protein,oral hairy leukoplakia

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 45-92 protein denotes Epstein-Barr virus BZLF1 transactivator protein
T2 124-137 protein denotes BZLF1 protein
T3 175-198 protein denotes immediate-early protein
T4 248-268 cell_type denotes EBV-infected B cells
T5 290-309 protein denotes monoclonal antibody
T6 311-314 protein denotes BZ1
T7 319-324 protein denotes BZLF1
T8 428-448 protein denotes active, dimeric form
T9 457-481 protein denotes inactive, monomeric form
T10 653-656 protein denotes BZ1
T11 657-676 protein denotes monoclonal antibody
T12 718-723 protein denotes BZLF1
T13 749-752 protein denotes BZ1
T14 847-861 DNA denotes BZLF1 promoter
T15 963-970 DNA denotes EBV DNA
T16 975-995 protein denotes viral capsid antigen
T17 1010-1013 protein denotes BZ1
T18 1040-1045 protein denotes BZLF1

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
1851858-0#70#92#gene1385 70-92 gene1385 denotes transactivator protein
1851858-0#96#118#diseaseC0206186 96-118 diseaseC0206186 denotes oral hairy leukoplakia
70#92#gene138596#118#diseaseC0206186 1851858-0#70#92#gene1385 1851858-0#96#118#diseaseC0206186 associated_with transactivator protein,oral hairy leukoplakia

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-119 Sentence denotes Differentiation-associated expression of the Epstein-Barr virus BZLF1 transactivator protein in oral hairy leukoplakia.
S2 120-269 Sentence denotes The BZLF1 protein of Epstein-Barr virus (EBV) is a key immediate-early protein which has been shown to disrupt virus latency in EBV-infected B cells.
S3 270-497 Sentence denotes We have generated a monoclonal antibody, BZ1, to BZLF1 which reacts in immunohistology, immunoblotting, and immunoprecipitation and which recognizes both the active, dimeric form and the inactive, monomeric form of the protein.
S4 498-677 Sentence denotes Biopsies of oral hairy leukoplakia, an AIDS-associated lesion characterized by high-level EBV replication, were examined by immunohistochemistry using the BZ1 monoclonal antibody.
S5 678-815 Sentence denotes A differentiation-associated pattern of BZLF1 expression was observed, BZ1 reacting with nuclei of the upper spinous layer of the lesion.
S6 816-921 Sentence denotes This finding suggests that the BZLF1 promoter may be regulated by the degree of squamous differentiation.
S7 922-1092 Sentence denotes A comparison of in situ hybridization to EBV DNA and viral capsid antigen staining with BZ1 reactivity suggested that BZLF1 expression precedes rampant virus replication.
S8 1093-1282 Sentence denotes The inability to detect EBV in the lower epithelial layers of oral hairy leukoplakia raises questions concerning the nature of EBV latency and persistence in stratified squamous epithelium.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 45-63 NP denotes Epstein-Barr virus
C2 64-92 NP denotes BZLF1 transactivator protein
C3 96-118 NP denotes oral hairy leukoplakia
C4 120-137 NP denotes The BZLF1 protein
C5 141-165 NP denotes Epstein-Barr virus (EBV)
C6 169-198 NP denotes a key immediate-early protein
C7 199-204 NP denotes which
C8 288-309 NP denotes a monoclonal antibody
C9 311-314 NP denotes BZ1
C10 319-324 NP denotes BZLF1
C11 325-330 NP denotes which
C12 402-407 NP denotes which
C13 485-496 NP denotes the protein
C14 510-532 NP denotes oral hairy leukoplakia
C16 588-591 NP denotes EBV
C15 534-603 NP denotes an AIDS-associated lesion characterized by high-level EBV replication
C18 718-723 NP denotes BZLF1
C17 718-734 NP denotes BZLF1 expression
C19 749-752 NP denotes BZ1
C20 963-966 NP denotes EBV
C21 1010-1013 NP denotes BZ1
C23 1040-1045 NP denotes BZLF1
C22 1040-1056 NP denotes BZLF1 expression
C24 1117-1120 NP denotes EBV
C25 1155-1177 NP denotes oral hairy leukoplakia
C26 1220-1223 NP denotes EBV
R1 C4 C2 coref-ident The BZLF1 protein,BZLF1 transactivator protein
R2 C5 C1 coref-ident Epstein-Barr virus (EBV),Epstein-Barr virus
R3 C7 C6 coref-relat which,a key immediate-early protein
R4 C8 C9 coref-appos a monoclonal antibody,BZ1
R5 C10 C4 coref-ident BZLF1,The BZLF1 protein
R6 C11 C10 coref-relat which,BZLF1
R7 C12 C10 coref-relat which,BZLF1
R8 C13 C10 coref-ident the protein,BZLF1
R9 C14 C3 coref-ident oral hairy leukoplakia,oral hairy leukoplakia
R10 C16 C5 coref-ident EBV,Epstein-Barr virus (EBV)
R11 C15 C14 coref-appos an AIDS-associated lesion characterized by high-level EBV replication,oral hairy leukoplakia
R12 C18 C10 coref-ident BZLF1,BZLF1
R13 C19 C9 coref-ident BZ1,BZ1
R14 C20 C16 coref-ident EBV,EBV
R15 C21 C19 coref-ident BZ1,BZ1
R16 C23 C18 coref-ident BZLF1,BZLF1
R17 C22 C17 coref-ident BZLF1 expression,BZLF1 expression
R18 C24 C20 coref-ident EBV,EBV
R19 C25 C14 coref-ident oral hairy leukoplakia,oral hairy leukoplakia
R20 C26 C24 coref-ident EBV,EBV

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 45-63 virus denotes Epstein-Barr virus
T2 96-118 other_name denotes oral hairy leukoplakia
T3 124-137 protein_molecule denotes BZLF1 protein
T4 141-159 virus denotes Epstein-Barr virus
T5 161-164 virus denotes EBV
T6 175-198 protein_family_or_group denotes immediate-early protein
T7 248-251 virus denotes EBV
T8 290-309 protein_family_or_group denotes monoclonal antibody
T9 311-314 protein_molecule denotes BZ1
T10 319-324 protein_molecule denotes BZLF1
T11 341-356 other_name denotes immunohistology
T12 358-372 other_name denotes immunoblotting
T13 378-397 other_name denotes immunoprecipitation
T14 428-448 protein_family_or_group denotes active, dimeric form
T15 457-481 protein_family_or_group denotes inactive, monomeric form
T16 510-532 other_name denotes oral hairy leukoplakia
T17 537-559 other_name denotes AIDS-associated lesion
T18 577-587 other_name denotes high-level
T19 588-591 virus denotes EBV
T20 622-642 other_name denotes immunohistochemistry
T21 653-656 protein_molecule denotes BZ1
T22 657-676 protein_family_or_group denotes monoclonal antibody
T23 680-714 other_name denotes differentiation-associated pattern
T24 718-723 protein_molecule denotes BZLF1
T25 749-752 protein_molecule denotes BZ1
T26 767-773 cell_component denotes nuclei
T27 781-800 tissue denotes upper spinous layer
T28 808-814 other_name denotes lesion
T29 847-852 protein_molecule denotes BZLF1
T30 941-959 other_name denotes situ hybridization
T31 963-966 virus denotes EBV
T32 975-995 protein_molecule denotes viral capsid antigen
T33 1010-1013 protein_molecule denotes BZ1
T34 1040-1045 protein_molecule denotes BZLF1
T35 1066-1091 other_name denotes rampant virus replication
T36 1117-1120 virus denotes EBV
T37 1155-1177 other_name denotes oral hairy leukoplakia
T38 1220-1223 virus denotes EBV
T39 1251-1281 tissue denotes stratified squamous epithelium