PubMed:17491223
Annnotations
LitCoin-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-118 | Sentence | denotes | Assessment of a new non-invasive index of cardiac performance for detection of dobutamine-induced myocardial ischemia. |
T2 | 119-130 | Sentence | denotes | BACKGROUND: |
T3 | 131-230 | Sentence | denotes | Electrocardiography has a very low sensitivity in detecting dobutamine-induced myocardial ischemia. |
T4 | 231-242 | Sentence | denotes | OBJECTIVES: |
T5 | 243-615 | Sentence | denotes | To assess the added diagnostic value of a new cardiac performance index (dP/dtejc) measurement, based on brachial artery flow changes, as compared to standard 12-lead ECG, for detecting dobutamine-induced myocardial ischemia, using Tc99m-Sestamibi single-photon emission computed tomography as the gold standard of comparison to assess the presence or absence of ischemia. |
T6 | 616-624 | Sentence | denotes | METHODS: |
T7 | 625-713 | Sentence | denotes | The study group comprised 40 patients undergoing Sestamibi-SPECT/dobutamine stress test. |
T8 | 714-816 | Sentence | denotes | Simultaneous measurements of ECG and brachial artery dP/dtejc were performed at each dobutamine level. |
T9 | 817-908 | Sentence | denotes | In 19 of the 40 patients perfusion defects compatible with ischemia were detected on SPECT. |
T10 | 909-1147 | Sentence | denotes | The increase in dP/dtejc during infusion of dobutamine in this group was severely impaired as compared to the non-ischemic group. dP/dtejc outcome was combined with the ECG results, giving an ECG-enhanced value, and compared to ECG alone. |
T11 | 1148-1156 | Sentence | denotes | RESULTS: |
T12 | 1157-1353 | Sentence | denotes | The sensitivity improved dramatically from 16% to 79%, positive predictive value increased from 60% to 68% and negative predictive value from 54% to 78%, and specificity decreased from 90% to 67%. |
T13 | 1354-1366 | Sentence | denotes | CONCLUSIONS: |
T14 | 1367-1625 | Sentence | denotes | If ECG alone is used for specificity, the combination with dP/dtejc improved the sensitivity of the test and could be a cost-savings alternative to cardiac imaging or perfusion studies to detect myocardial ischemia, especially in patients unable to exercise. |
LitCoin-entities
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
4104 | 79-89 | ChemicalEntity | denotes | dobutamine | MESH:D004280 |
4105 | 98-117 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | MESH:D017202 |
4106 | 191-201 | ChemicalEntity | denotes | dobutamine | MESH:D004280 |
4107 | 210-229 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | MESH:D017202 |
4108 | 429-439 | ChemicalEntity | denotes | dobutamine | MESH:D004280 |
4109 | 448-467 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | MESH:D017202 |
4110 | 606-614 | DiseaseOrPhenotypicFeature | denotes | ischemia | MESH:D007511 |
4111 | 654-662 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
4112 | 690-700 | ChemicalEntity | denotes | dobutamine | MESH:D004280 |
4113 | 799-809 | ChemicalEntity | denotes | dobutamine | MESH:D004280 |
4114 | 833-841 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
4115 | 876-884 | DiseaseOrPhenotypicFeature | denotes | ischemia | MESH:D007511 |
4116 | 953-963 | ChemicalEntity | denotes | dobutamine | MESH:D004280 |
4117 | 1562-1581 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | MESH:D017202 |
4118 | 1597-1605 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
LitCoin_Mondo
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 98-117 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | 0024644 |
T2 | 210-229 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | 0024644 |
T3 | 448-467 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | 0024644 |
T4 | 1562-1581 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | 0024644 |
LitCoin-GeneOrGeneProduct-v2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 541-545 | GeneOrGeneProduct | denotes | gold |
LitCoin-GeneOrGeneProduct-v0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 90-97 | GeneOrGeneProduct | denotes | induced |
T2 | 151-156 | GeneOrGeneProduct | denotes | has a |
T3 | 202-209 | GeneOrGeneProduct | denotes | induced |
T4 | 274-279 | GeneOrGeneProduct | denotes | value |
T5 | 339-344 | GeneOrGeneProduct | denotes | based |
T6 | 440-447 | GeneOrGeneProduct | denotes | induced |
T7 | 541-545 | GeneOrGeneProduct | denotes | gold |
T8 | 616-623 | GeneOrGeneProduct | denotes | METHODS |
T9 | 708-712 | GeneOrGeneProduct | denotes | test |
T10 | 817-822 | GeneOrGeneProduct | denotes | In 19 |
T11 | 852-859 | GeneOrGeneProduct | denotes | defects |
T12 | 1114-1119 | GeneOrGeneProduct | denotes | value |
T13 | 1221-1231 | GeneOrGeneProduct | denotes | predictive |
T14 | 1232-1237 | GeneOrGeneProduct | denotes | value |
T15 | 1277-1287 | GeneOrGeneProduct | denotes | predictive |
T16 | 1288-1293 | GeneOrGeneProduct | denotes | value |
T17 | 1467-1471 | GeneOrGeneProduct | denotes | test |
T18 | 1487-1491 | GeneOrGeneProduct | denotes | cost |
LitCoin-Disease-MeSH
Id | Subject | Object | Predicate | Lexical cue | originalLabel |
---|---|---|---|---|---|
T1 | 98-117 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 |
T2 | 210-229 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 |
T3 | 448-467 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 |
T4 | 606-614 | DiseaseOrPhenotypicFeature | denotes | ischemia | D007511 |
T5 | 876-884 | DiseaseOrPhenotypicFeature | denotes | ischemia | D007511 |
T6 | 1023-1031 | DiseaseOrPhenotypicFeature | denotes | ischemic | DISEASE |
T7 | 1562-1581 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 |
LitCoin-GeneOrGeneProduct-v3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 541-545 | GeneOrGeneProduct | denotes | gold |
LitCoin_Mondo_095
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 98-117 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | 0024644 |
T2 | 166-177 | DiseaseOrPhenotypicFeature | denotes | sensitivity | 0000605 |
T3 | 210-229 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | 0024644 |
T4 | 448-467 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | 0024644 |
T5 | 606-614 | DiseaseOrPhenotypicFeature | denotes | ischemia | 0005053 |
T6 | 876-884 | DiseaseOrPhenotypicFeature | denotes | ischemia | 0005053 |
T7 | 1161-1172 | DiseaseOrPhenotypicFeature | denotes | sensitivity | 0000605 |
T8 | 1448-1459 | DiseaseOrPhenotypicFeature | denotes | sensitivity | 0000605 |
T9 | 1562-1581 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | 0024644 |
LitCoin-MeSH-Disease-2
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 98-117 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 |
T2 | 210-229 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 |
T3 | 448-467 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 |
T4 | 606-614 | DiseaseOrPhenotypicFeature | denotes | ischemia | D007511 |
T5 | 876-884 | DiseaseOrPhenotypicFeature | denotes | ischemia | D007511 |
T6 | 1023-1031 | DiseaseOrPhenotypicFeature | denotes | ischemic | DISEASE |
T7 | 1562-1581 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 |
LitCoin-MONDO_bioort2019
Id | Subject | Object | Predicate | Lexical cue | #label |
---|---|---|---|---|---|
T1 | 98-117 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 |
T2 | 210-229 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 |
T3 | 448-467 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 |
T4 | 606-614 | DiseaseOrPhenotypicFeature | denotes | ischemia | D007511 |
T5 | 876-884 | DiseaseOrPhenotypicFeature | denotes | ischemia | D007511 |
T6 | 1023-1031 | DiseaseOrPhenotypicFeature | denotes | ischemic | DISEASE |
T7 | 1562-1581 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 |
LitCoin-NCBITaxon-2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 654-662 | OrganismTaxon | denotes | patients |
T2 | 833-841 | OrganismTaxon | denotes | patients |
T3 | 1597-1605 | OrganismTaxon | denotes | patients |
LitCoin-Chemical-MeSH-CHEBI
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 79-89 | ChemicalEntity | denotes | dobutamine | D004280|http://purl.obolibrary.org/obo/CHEBI_4670 |
T3 | 191-201 | ChemicalEntity | denotes | dobutamine | D004280|http://purl.obolibrary.org/obo/CHEBI_4670 |
T5 | 405-409 | ChemicalEntity | denotes | lead | D007854 |
T6 | 410-413 | ChemicalEntity | denotes | ECG | http://purl.obolibrary.org/obo/CHEBI_70255 |
T7 | 429-439 | ChemicalEntity | denotes | dobutamine | D004280|http://purl.obolibrary.org/obo/CHEBI_4670 |
T9 | 541-545 | ChemicalEntity | denotes | gold | D006046|http://purl.obolibrary.org/obo/CHEBI_30050|http://purl.obolibrary.org/obo/CHEBI_29287 |
T12 | 690-700 | ChemicalEntity | denotes | dobutamine | D004280|http://purl.obolibrary.org/obo/CHEBI_4670 |
T14 | 743-746 | ChemicalEntity | denotes | ECG | http://purl.obolibrary.org/obo/CHEBI_70255 |
T15 | 799-809 | ChemicalEntity | denotes | dobutamine | D004280|http://purl.obolibrary.org/obo/CHEBI_4670 |
T17 | 953-963 | ChemicalEntity | denotes | dobutamine | D004280|http://purl.obolibrary.org/obo/CHEBI_4670 |
T19 | 1078-1081 | ChemicalEntity | denotes | ECG | http://purl.obolibrary.org/obo/CHEBI_70255 |
T20 | 1101-1104 | ChemicalEntity | denotes | ECG | http://purl.obolibrary.org/obo/CHEBI_70255 |
T21 | 1137-1140 | ChemicalEntity | denotes | ECG | http://purl.obolibrary.org/obo/CHEBI_70255 |
T22 | 1370-1373 | ChemicalEntity | denotes | ECG | http://purl.obolibrary.org/obo/CHEBI_70255 |
LitCoin-training-merged
Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
---|---|---|---|---|---|---|
T22 | 1370-1373 | ChemicalEntity | denotes | ECG | http://purl.obolibrary.org/obo/CHEBI_70255 | |
T21 | 1137-1140 | ChemicalEntity | denotes | ECG | http://purl.obolibrary.org/obo/CHEBI_70255 | |
T20 | 1101-1104 | ChemicalEntity | denotes | ECG | http://purl.obolibrary.org/obo/CHEBI_70255 | |
T19 | 1078-1081 | ChemicalEntity | denotes | ECG | http://purl.obolibrary.org/obo/CHEBI_70255 | |
T17 | 953-963 | ChemicalEntity | denotes | dobutamine | http://purl.obolibrary.org/obo/CHEBI_4670|D004280 | |
T15 | 799-809 | ChemicalEntity | denotes | dobutamine | http://purl.obolibrary.org/obo/CHEBI_4670|D004280 | |
T14 | 743-746 | ChemicalEntity | denotes | ECG | http://purl.obolibrary.org/obo/CHEBI_70255 | |
T12 | 690-700 | ChemicalEntity | denotes | dobutamine | http://purl.obolibrary.org/obo/CHEBI_4670|D004280 | |
T9 | 541-545 | ChemicalEntity | denotes | gold | http://purl.obolibrary.org/obo/CHEBI_29287|http://purl.obolibrary.org/obo/CHEBI_30050|D006046 | |
T7 | 429-439 | ChemicalEntity | denotes | dobutamine | http://purl.obolibrary.org/obo/CHEBI_4670|D004280 | |
T6 | 410-413 | ChemicalEntity | denotes | ECG | http://purl.obolibrary.org/obo/CHEBI_70255 | |
T5 | 405-409 | ChemicalEntity | denotes | lead | D007854 | |
T3 | 191-201 | ChemicalEntity | denotes | dobutamine | http://purl.obolibrary.org/obo/CHEBI_4670|D004280 | |
T1 | 79-89 | ChemicalEntity | denotes | dobutamine | http://purl.obolibrary.org/obo/CHEBI_4670|D004280 | |
T43625 | 541-545 | GeneOrGeneProduct | denotes | gold | ||
T34519 | 1562-1581 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 | |
T33969 | 1023-1031 | DiseaseOrPhenotypicFeature | denotes | ischemic | DISEASE | |
T56614 | 876-884 | DiseaseOrPhenotypicFeature | denotes | ischemia | D007511 | |
T4 | 606-614 | DiseaseOrPhenotypicFeature | denotes | ischemia | D007511 | |
T33131 | 448-467 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 | |
T2 | 210-229 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 | |
T48866 | 98-117 | DiseaseOrPhenotypicFeature | denotes | myocardial ischemia | D017202 | |
T44149 | 1597-1605 | OrganismTaxon | denotes | patients | ||
T72067 | 833-841 | OrganismTaxon | denotes | patients | ||
T38278 | 654-662 | OrganismTaxon | denotes | patients |