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PubMed:17491223 JSONTXT

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LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-118 Sentence denotes Assessment of a new non-invasive index of cardiac performance for detection of dobutamine-induced myocardial ischemia.
T2 119-130 Sentence denotes BACKGROUND:
T3 131-230 Sentence denotes Electrocardiography has a very low sensitivity in detecting dobutamine-induced myocardial ischemia.
T4 231-242 Sentence denotes OBJECTIVES:
T5 243-615 Sentence denotes To assess the added diagnostic value of a new cardiac performance index (dP/dtejc) measurement, based on brachial artery flow changes, as compared to standard 12-lead ECG, for detecting dobutamine-induced myocardial ischemia, using Tc99m-Sestamibi single-photon emission computed tomography as the gold standard of comparison to assess the presence or absence of ischemia.
T6 616-624 Sentence denotes METHODS:
T7 625-713 Sentence denotes The study group comprised 40 patients undergoing Sestamibi-SPECT/dobutamine stress test.
T8 714-816 Sentence denotes Simultaneous measurements of ECG and brachial artery dP/dtejc were performed at each dobutamine level.
T9 817-908 Sentence denotes In 19 of the 40 patients perfusion defects compatible with ischemia were detected on SPECT.
T10 909-1147 Sentence denotes The increase in dP/dtejc during infusion of dobutamine in this group was severely impaired as compared to the non-ischemic group. dP/dtejc outcome was combined with the ECG results, giving an ECG-enhanced value, and compared to ECG alone.
T11 1148-1156 Sentence denotes RESULTS:
T12 1157-1353 Sentence denotes The sensitivity improved dramatically from 16% to 79%, positive predictive value increased from 60% to 68% and negative predictive value from 54% to 78%, and specificity decreased from 90% to 67%.
T13 1354-1366 Sentence denotes CONCLUSIONS:
T14 1367-1625 Sentence denotes If ECG alone is used for specificity, the combination with dP/dtejc improved the sensitivity of the test and could be a cost-savings alternative to cardiac imaging or perfusion studies to detect myocardial ischemia, especially in patients unable to exercise.

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
4104 79-89 ChemicalEntity denotes dobutamine MESH:D004280
4105 98-117 DiseaseOrPhenotypicFeature denotes myocardial ischemia MESH:D017202
4106 191-201 ChemicalEntity denotes dobutamine MESH:D004280
4107 210-229 DiseaseOrPhenotypicFeature denotes myocardial ischemia MESH:D017202
4108 429-439 ChemicalEntity denotes dobutamine MESH:D004280
4109 448-467 DiseaseOrPhenotypicFeature denotes myocardial ischemia MESH:D017202
4110 606-614 DiseaseOrPhenotypicFeature denotes ischemia MESH:D007511
4111 654-662 OrganismTaxon denotes patients NCBITaxon:9606
4112 690-700 ChemicalEntity denotes dobutamine MESH:D004280
4113 799-809 ChemicalEntity denotes dobutamine MESH:D004280
4114 833-841 OrganismTaxon denotes patients NCBITaxon:9606
4115 876-884 DiseaseOrPhenotypicFeature denotes ischemia MESH:D007511
4116 953-963 ChemicalEntity denotes dobutamine MESH:D004280
4117 1562-1581 DiseaseOrPhenotypicFeature denotes myocardial ischemia MESH:D017202
4118 1597-1605 OrganismTaxon denotes patients NCBITaxon:9606

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 98-117 DiseaseOrPhenotypicFeature denotes myocardial ischemia 0024644
T2 210-229 DiseaseOrPhenotypicFeature denotes myocardial ischemia 0024644
T3 448-467 DiseaseOrPhenotypicFeature denotes myocardial ischemia 0024644
T4 1562-1581 DiseaseOrPhenotypicFeature denotes myocardial ischemia 0024644

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 541-545 GeneOrGeneProduct denotes gold

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 90-97 GeneOrGeneProduct denotes induced
T2 151-156 GeneOrGeneProduct denotes has a
T3 202-209 GeneOrGeneProduct denotes induced
T4 274-279 GeneOrGeneProduct denotes value
T5 339-344 GeneOrGeneProduct denotes based
T6 440-447 GeneOrGeneProduct denotes induced
T7 541-545 GeneOrGeneProduct denotes gold
T8 616-623 GeneOrGeneProduct denotes METHODS
T9 708-712 GeneOrGeneProduct denotes test
T10 817-822 GeneOrGeneProduct denotes In 19
T11 852-859 GeneOrGeneProduct denotes defects
T12 1114-1119 GeneOrGeneProduct denotes value
T13 1221-1231 GeneOrGeneProduct denotes predictive
T14 1232-1237 GeneOrGeneProduct denotes value
T15 1277-1287 GeneOrGeneProduct denotes predictive
T16 1288-1293 GeneOrGeneProduct denotes value
T17 1467-1471 GeneOrGeneProduct denotes test
T18 1487-1491 GeneOrGeneProduct denotes cost

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 98-117 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T2 210-229 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T3 448-467 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T4 606-614 DiseaseOrPhenotypicFeature denotes ischemia D007511
T5 876-884 DiseaseOrPhenotypicFeature denotes ischemia D007511
T6 1023-1031 DiseaseOrPhenotypicFeature denotes ischemic DISEASE
T7 1562-1581 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 541-545 GeneOrGeneProduct denotes gold

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 98-117 DiseaseOrPhenotypicFeature denotes myocardial ischemia 0024644
T2 166-177 DiseaseOrPhenotypicFeature denotes sensitivity 0000605
T3 210-229 DiseaseOrPhenotypicFeature denotes myocardial ischemia 0024644
T4 448-467 DiseaseOrPhenotypicFeature denotes myocardial ischemia 0024644
T5 606-614 DiseaseOrPhenotypicFeature denotes ischemia 0005053
T6 876-884 DiseaseOrPhenotypicFeature denotes ischemia 0005053
T7 1161-1172 DiseaseOrPhenotypicFeature denotes sensitivity 0000605
T8 1448-1459 DiseaseOrPhenotypicFeature denotes sensitivity 0000605
T9 1562-1581 DiseaseOrPhenotypicFeature denotes myocardial ischemia 0024644

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 98-117 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T2 210-229 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T3 448-467 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T4 606-614 DiseaseOrPhenotypicFeature denotes ischemia D007511
T5 876-884 DiseaseOrPhenotypicFeature denotes ischemia D007511
T6 1023-1031 DiseaseOrPhenotypicFeature denotes ischemic DISEASE
T7 1562-1581 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 98-117 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T2 210-229 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T3 448-467 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T4 606-614 DiseaseOrPhenotypicFeature denotes ischemia D007511
T5 876-884 DiseaseOrPhenotypicFeature denotes ischemia D007511
T6 1023-1031 DiseaseOrPhenotypicFeature denotes ischemic DISEASE
T7 1562-1581 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 654-662 OrganismTaxon denotes patients
T2 833-841 OrganismTaxon denotes patients
T3 1597-1605 OrganismTaxon denotes patients

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 79-89 ChemicalEntity denotes dobutamine D004280|http://purl.obolibrary.org/obo/CHEBI_4670
T3 191-201 ChemicalEntity denotes dobutamine D004280|http://purl.obolibrary.org/obo/CHEBI_4670
T5 405-409 ChemicalEntity denotes lead D007854
T6 410-413 ChemicalEntity denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255
T7 429-439 ChemicalEntity denotes dobutamine D004280|http://purl.obolibrary.org/obo/CHEBI_4670
T9 541-545 ChemicalEntity denotes gold D006046|http://purl.obolibrary.org/obo/CHEBI_30050|http://purl.obolibrary.org/obo/CHEBI_29287
T12 690-700 ChemicalEntity denotes dobutamine D004280|http://purl.obolibrary.org/obo/CHEBI_4670
T14 743-746 ChemicalEntity denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255
T15 799-809 ChemicalEntity denotes dobutamine D004280|http://purl.obolibrary.org/obo/CHEBI_4670
T17 953-963 ChemicalEntity denotes dobutamine D004280|http://purl.obolibrary.org/obo/CHEBI_4670
T19 1078-1081 ChemicalEntity denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255
T20 1101-1104 ChemicalEntity denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255
T21 1137-1140 ChemicalEntity denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255
T22 1370-1373 ChemicalEntity denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T22 1370-1373 ChemicalEntity denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255
T21 1137-1140 ChemicalEntity denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255
T20 1101-1104 ChemicalEntity denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255
T19 1078-1081 ChemicalEntity denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255
T17 953-963 ChemicalEntity denotes dobutamine http://purl.obolibrary.org/obo/CHEBI_4670|D004280
T15 799-809 ChemicalEntity denotes dobutamine http://purl.obolibrary.org/obo/CHEBI_4670|D004280
T14 743-746 ChemicalEntity denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255
T12 690-700 ChemicalEntity denotes dobutamine http://purl.obolibrary.org/obo/CHEBI_4670|D004280
T9 541-545 ChemicalEntity denotes gold http://purl.obolibrary.org/obo/CHEBI_29287|http://purl.obolibrary.org/obo/CHEBI_30050|D006046
T7 429-439 ChemicalEntity denotes dobutamine http://purl.obolibrary.org/obo/CHEBI_4670|D004280
T6 410-413 ChemicalEntity denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255
T5 405-409 ChemicalEntity denotes lead D007854
T3 191-201 ChemicalEntity denotes dobutamine http://purl.obolibrary.org/obo/CHEBI_4670|D004280
T1 79-89 ChemicalEntity denotes dobutamine http://purl.obolibrary.org/obo/CHEBI_4670|D004280
T43625 541-545 GeneOrGeneProduct denotes gold
T34519 1562-1581 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T33969 1023-1031 DiseaseOrPhenotypicFeature denotes ischemic DISEASE
T56614 876-884 DiseaseOrPhenotypicFeature denotes ischemia D007511
T4 606-614 DiseaseOrPhenotypicFeature denotes ischemia D007511
T33131 448-467 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T2 210-229 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T48866 98-117 DiseaseOrPhenotypicFeature denotes myocardial ischemia D017202
T44149 1597-1605 OrganismTaxon denotes patients
T72067 833-841 OrganismTaxon denotes patients
T38278 654-662 OrganismTaxon denotes patients