PubMed:17192049 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/17192049","sourcedb":"PubMed","sourceid":"17192049","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/17192049","text":"Cytochrome p4501A1 gene variants as susceptibility marker for prostate cancer.\nCYP1A1 activates environmental procarcinogens and catalyzes oxidative metabolism of estrogens and is likely to play an important role in the etiology of prostate cancer. To evaluate this phenomenon, the association between two single nucleotide polymorphisms (A to G transition in exon7 leading to amino acid substitution Ile462Val and T3801C at 3'UTR) of CYP1A1 gene in prostate cancer were analyzed in a case-control study of 100 individuals in South Indian population. The estimated relative risk was significantly high for individuals with w1/m1 genotype at 3'UTR of CYP1A1 gene (OR-4.64; 95%CI = 1.51-14.86; P \u003c 0.01) whereas the CYP1A1 Ile/Val genotype (w2/m2) on exon 7 was found to be associated with a decreased risk for prostate cancer (OR-0.17; 95%CI = 0.02-0.89; P=0.03). A Stratified analysis of the genotypes with age of onset and tumor grade showed the w1/m1 genotype to be significantly associated with an early age of onset; however the tumor grades did not have significant association with the variant genotypes. Thus the present study indicates that individuals with the variant w1/m1 genotype exhibit an increased risk while those with w2/m2 genotype exhibit a decreased risk for prostate cancer.","tracks":[{"project":"PubTator4TogoVar","denotations":[{"id":"17192049_0","span":{"begin":401,"end":410},"obj":"ProteinMutation"},{"id":"17192049_1","span":{"begin":721,"end":728},"obj":"ProteinMutation"}],"attributes":[{"id":"17192049_0_ProteinMutation","pred":"proteinmutation","subj":"17192049_0","obj":"rs1048943"},{"id":"17192049_1_ProteinMutation","pred":"proteinmutation","subj":"17192049_1","obj":"rs1048943"},{"subj":"17192049_0","pred":"source","obj":"PubTator4TogoVar"},{"subj":"17192049_1","pred":"source","obj":"PubTator4TogoVar"}]},{"project":"LitCoin-entities","denotations":[{"id":"3792","span":{"begin":0,"end":18},"obj":"GeneOrGeneProduct"},{"id":"3793","span":{"begin":62,"end":77},"obj":"DiseaseOrPhenotypicFeature"},{"id":"3794","span":{"begin":79,"end":85},"obj":"GeneOrGeneProduct"},{"id":"3795","span":{"begin":232,"end":247},"obj":"DiseaseOrPhenotypicFeature"},{"id":"3796","span":{"begin":339,"end":345},"obj":"SequenceVariant"},{"id":"3797","span":{"begin":401,"end":410},"obj":"SequenceVariant"},{"id":"3798","span":{"begin":415,"end":421},"obj":"SequenceVariant"},{"id":"3799","span":{"begin":435,"end":441},"obj":"GeneOrGeneProduct"},{"id":"3800","span":{"begin":450,"end":465},"obj":"DiseaseOrPhenotypicFeature"},{"id":"3801","span":{"begin":650,"end":656},"obj":"GeneOrGeneProduct"},{"id":"3802","span":{"begin":714,"end":720},"obj":"GeneOrGeneProduct"},{"id":"3803","span":{"begin":721,"end":728},"obj":"SequenceVariant"},{"id":"3804","span":{"begin":809,"end":824},"obj":"DiseaseOrPhenotypicFeature"},{"id":"3805","span":{"begin":924,"end":929},"obj":"DiseaseOrPhenotypicFeature"},{"id":"3806","span":{"begin":1033,"end":1038},"obj":"DiseaseOrPhenotypicFeature"},{"id":"3807","span":{"begin":1280,"end":1295},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"db_id","subj":"3792","obj":"NCBIGene:1543"},{"id":"A2","pred":"db_id","subj":"3793","obj":"MESH:D011471"},{"id":"A3","pred":"db_id","subj":"3794","obj":"NCBIGene:1543"},{"id":"A4","pred":"db_id","subj":"3795","obj":"MESH:D011471"},{"id":"A5","pred":"db_id","subj":"3796","obj":"DBSNP:rs1048943"},{"id":"A6","pred":"db_id","subj":"3797","obj":"DBSNP:rs1048943"},{"id":"A7","pred":"db_id","subj":"3798","obj":"g|SUB|T|3801|C"},{"id":"A8","pred":"db_id","subj":"3799","obj":"NCBIGene:1543"},{"id":"A9","pred":"db_id","subj":"3800","obj":"MESH:D011471"},{"id":"A10","pred":"db_id","subj":"3801","obj":"NCBIGene:1543"},{"id":"A11","pred":"db_id","subj":"3802","obj":"NCBIGene:1543"},{"id":"A12","pred":"db_id","subj":"3803","obj":"DBSNP:rs1048943"},{"id":"A13","pred":"db_id","subj":"3804","obj":"MESH:D011471"},{"id":"A14","pred":"db_id","subj":"3805","obj":"MESH:D009369"},{"id":"A15","pred":"db_id","subj":"3806","obj":"MESH:D009369"},{"id":"A16","pred":"db_id","subj":"3807","obj":"MESH:D011471"},{"subj":"3792","pred":"source","obj":"LitCoin-entities"},{"subj":"3793","pred":"source","obj":"LitCoin-entities"},{"subj":"3794","pred":"source","obj":"LitCoin-entities"},{"subj":"3795","pred":"source","obj":"LitCoin-entities"},{"subj":"3796","pred":"source","obj":"LitCoin-entities"},{"subj":"3797","pred":"source","obj":"LitCoin-entities"},{"subj":"3798","pred":"source","obj":"LitCoin-entities"},{"subj":"3799","pred":"source","obj":"LitCoin-entities"},{"subj":"3800","pred":"source","obj":"LitCoin-entities"},{"subj":"3801","pred":"source","obj":"LitCoin-entities"},{"subj":"3802","pred":"source","obj":"LitCoin-entities"},{"subj":"3803","pred":"source","obj":"LitCoin-entities"},{"subj":"3804","pred":"source","obj":"LitCoin-entities"},{"subj":"3805","pred":"source","obj":"LitCoin-entities"},{"subj":"3806","pred":"source","obj":"LitCoin-entities"},{"subj":"3807","pred":"source","obj":"LitCoin-entities"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}]},{"project":"LitCoin-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":78},"obj":"Sentence"},{"id":"T2","span":{"begin":79,"end":248},"obj":"Sentence"},{"id":"T3","span":{"begin":249,"end":550},"obj":"Sentence"},{"id":"T4","span":{"begin":551,"end":862},"obj":"Sentence"},{"id":"T5","span":{"begin":863,"end":1110},"obj":"Sentence"},{"id":"T6","span":{"begin":1111,"end":1296},"obj":"Sentence"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-sentences"},{"subj":"T2","pred":"source","obj":"LitCoin-sentences"},{"subj":"T3","pred":"source","obj":"LitCoin-sentences"},{"subj":"T4","pred":"source","obj":"LitCoin-sentences"},{"subj":"T5","pred":"source","obj":"LitCoin-sentences"},{"subj":"T6","pred":"source","obj":"LitCoin-sentences"}]},{"project":"LitCoin_Mondo","denotations":[{"id":"T1","span":{"begin":62,"end":77},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":71,"end":77},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":232,"end":247},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":241,"end":247},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":450,"end":465},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":459,"end":465},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":809,"end":824},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":818,"end":824},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":1280,"end":1295},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":1289,"end":1295},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A8","pred":"mondo_id","subj":"T8","obj":"0004992"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0008315"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"0004992"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"0008315"},{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0008315"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0004992"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"0008315"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0004992"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"0008315"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"0004992"},{"subj":"T1","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T2","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T3","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T4","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T5","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T6","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T7","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T8","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T9","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T10","pred":"source","obj":"LitCoin_Mondo"}]},{"project":"LitCoin-SeqVar","denotations":[{"id":"T1","span":{"begin":401,"end":410},"obj":"SequenceVariant"},{"id":"T2","span":{"begin":415,"end":421},"obj":"SequenceVariant"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-SeqVar"},{"subj":"T2","pred":"source","obj":"LitCoin-SeqVar"}]},{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T1","span":{"begin":0,"end":10},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":79,"end":85},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":86,"end":95},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":180,"end":186},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":377,"end":387},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":425,"end":430},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":435,"end":441},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":480,"end":484},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":485,"end":489},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":597,"end":601},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":641,"end":646},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":650,"end":656},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":714,"end":720},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":721,"end":724},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":739,"end":741},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":924,"end":929},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":1001,"end":1006},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":1033,"end":1038},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":1236,"end":1238},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"}]},{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T1","span":{"begin":0,"end":10},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":79,"end":85},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":377,"end":387},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":425,"end":430},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":435,"end":441},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":597,"end":601},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":641,"end":646},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":650,"end":656},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":714,"end":720},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":1001,"end":1006},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"}]},{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T1","span":{"begin":62,"end":77},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":232,"end":247},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":450,"end":465},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":809,"end":824},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":924,"end":929},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1033,"end":1038},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":1280,"end":1295},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"originalLabel","subj":"T1","obj":"D011471"},{"id":"A2","pred":"originalLabel","subj":"T2","obj":"D011471"},{"id":"A3","pred":"originalLabel","subj":"T3","obj":"D011471"},{"id":"A4","pred":"originalLabel","subj":"T4","obj":"D011471"},{"id":"A5","pred":"originalLabel","subj":"T5","obj":"D009369"},{"id":"A6","pred":"originalLabel","subj":"T6","obj":"D009369"},{"id":"A7","pred":"originalLabel","subj":"T7","obj":"D011471"},{"subj":"T1","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T2","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T3","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T4","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T5","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T6","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T7","pred":"source","obj":"LitCoin-Disease-MeSH"}]},{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T1","span":{"begin":0,"end":10},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":79,"end":85},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":435,"end":441},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":650,"end":656},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":714,"end":720},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"}]},{"project":"LitCoin_Mondo_095","denotations":[{"id":"T1","span":{"begin":62,"end":77},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":232,"end":247},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":450,"end":465},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":809,"end":824},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":924,"end":929},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1033,"end":1038},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":1280,"end":1295},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0008315"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0008315"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0008315"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0008315"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"0005070"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"0005070"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"0008315"},{"subj":"T1","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T2","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T3","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T4","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T5","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T6","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T7","pred":"source","obj":"LitCoin_Mondo_095"}]},{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T1","span":{"begin":62,"end":77},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":232,"end":247},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":450,"end":465},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":809,"end":824},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":924,"end":929},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1033,"end":1038},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":1280,"end":1295},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"ID:","subj":"T1","obj":"D011471"},{"id":"A2","pred":"ID:","subj":"T2","obj":"D011471"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D011471"},{"id":"A4","pred":"ID:","subj":"T4","obj":"D011471"},{"id":"A5","pred":"ID:","subj":"T5","obj":"D009369"},{"id":"A6","pred":"ID:","subj":"T6","obj":"D009369"},{"id":"A7","pred":"ID:","subj":"T7","obj":"D011471"},{"subj":"T1","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T2","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T3","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T4","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T5","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T6","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T7","pred":"source","obj":"LitCoin-MeSH-Disease-2"}]},{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T1","span":{"begin":62,"end":77},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":232,"end":247},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":450,"end":465},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":809,"end":824},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":924,"end":929},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1033,"end":1038},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":1280,"end":1295},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"#label","subj":"T1","obj":"D011471"},{"id":"A2","pred":"#label","subj":"T2","obj":"D011471"},{"id":"A3","pred":"#label","subj":"T3","obj":"D011471"},{"id":"A4","pred":"#label","subj":"T4","obj":"D011471"},{"id":"A5","pred":"#label","subj":"T5","obj":"D009369"},{"id":"A6","pred":"#label","subj":"T6","obj":"D009369"},{"id":"A7","pred":"#label","subj":"T7","obj":"D011471"},{"subj":"T1","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T2","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T3","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T4","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T5","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T6","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T7","pred":"source","obj":"LitCoin-MONDO_bioort2019"}]},{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T1","span":{"begin":0,"end":10},"obj":"ChemicalEntity"},{"id":"T2","span":{"begin":721,"end":728},"obj":"ChemicalEntity"}],"attributes":[{"id":"A1","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_4056"},{"id":"A2","pred":"ID:","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_74327"},{"subj":"T1","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T2","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"}]},{"project":"LitCoin-training-merged","denotations":[{"id":"T2","span":{"begin":721,"end":728},"obj":"ChemicalEntity"},{"id":"T1","span":{"begin":0,"end":10},"obj":"ChemicalEntity"},{"id":"T5","span":{"begin":714,"end":720},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":650,"end":656},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":435,"end":441},"obj":"GeneOrGeneProduct"},{"id":"T56189","span":{"begin":79,"end":85},"obj":"GeneOrGeneProduct"},{"id":"T20753","span":{"begin":0,"end":10},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":1280,"end":1295},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1033,"end":1038},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T79632","span":{"begin":924,"end":929},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T49358","span":{"begin":809,"end":824},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11620","span":{"begin":450,"end":465},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T42149","span":{"begin":232,"end":247},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T55539","span":{"begin":62,"end":77},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T97576","span":{"begin":415,"end":421},"obj":"SequenceVariant"},{"id":"T16484","span":{"begin":401,"end":410},"obj":"SequenceVariant"}],"attributes":[{"id":"A2","pred":"ID:","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_74327"},{"id":"A1","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_4056"},{"id":"A7","pred":"#label","subj":"T7","obj":"D011471"},{"id":"A6","pred":"#label","subj":"T6","obj":"D009369"},{"id":"A5","pred":"#label","subj":"T79632","obj":"D009369"},{"id":"A4","pred":"#label","subj":"T49358","obj":"D011471"},{"id":"A3","pred":"#label","subj":"T11620","obj":"D011471"},{"id":"A7946","pred":"#label","subj":"T42149","obj":"D011471"},{"id":"A99058","pred":"#label","subj":"T55539","obj":"D011471"},{"subj":"T2","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T1","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T5","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T4","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T3","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T56189","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T20753","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T7","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T6","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T79632","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T49358","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T11620","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T42149","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T55539","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T97576","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T16484","pred":"source","obj":"LitCoin-training-merged"}]},{"project":"DisGeNET","denotations":[{"id":"T0","span":{"begin":643,"end":646},"obj":"gene:8170"},{"id":"T1","span":{"begin":809,"end":824},"obj":"disease:C0376358"},{"id":"T2","span":{"begin":643,"end":646},"obj":"gene:8170"},{"id":"T3","span":{"begin":809,"end":824},"obj":"disease:C0600139"},{"id":"T4","span":{"begin":643,"end":646},"obj":"gene:2837"},{"id":"T5","span":{"begin":809,"end":824},"obj":"disease:C0376358"},{"id":"T6","span":{"begin":643,"end":646},"obj":"gene:2837"},{"id":"T7","span":{"begin":809,"end":824},"obj":"disease:C0600139"},{"id":"T8","span":{"begin":650,"end":656},"obj":"gene:1543"},{"id":"T9","span":{"begin":809,"end":824},"obj":"disease:C0376358"},{"id":"T10","span":{"begin":650,"end":656},"obj":"gene:1543"},{"id":"T11","span":{"begin":809,"end":824},"obj":"disease:C0600139"},{"id":"T12","span":{"begin":714,"end":720},"obj":"gene:1543"},{"id":"T13","span":{"begin":809,"end":824},"obj":"disease:C0376358"},{"id":"T14","span":{"begin":714,"end":720},"obj":"gene:1543"},{"id":"T15","span":{"begin":809,"end":824},"obj":"disease:C0600139"}],"relations":[{"id":"R1","pred":"associated_with","subj":"T0","obj":"T1"},{"id":"R2","pred":"associated_with","subj":"T2","obj":"T3"},{"id":"R3","pred":"associated_with","subj":"T4","obj":"T5"},{"id":"R4","pred":"associated_with","subj":"T6","obj":"T7"},{"id":"R5","pred":"associated_with","subj":"T8","obj":"T9"},{"id":"R6","pred":"associated_with","subj":"T10","obj":"T11"},{"id":"R7","pred":"associated_with","subj":"T12","obj":"T13"},{"id":"R8","pred":"associated_with","subj":"T14","obj":"T15"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"attributes":[{"subj":"T0","pred":"source","obj":"DisGeNET"},{"subj":"T1","pred":"source","obj":"DisGeNET"},{"subj":"T2","pred":"source","obj":"DisGeNET"},{"subj":"T3","pred":"source","obj":"DisGeNET"},{"subj":"T4","pred":"source","obj":"DisGeNET"},{"subj":"T5","pred":"source","obj":"DisGeNET"},{"subj":"T6","pred":"source","obj":"DisGeNET"},{"subj":"T7","pred":"source","obj":"DisGeNET"},{"subj":"T8","pred":"source","obj":"DisGeNET"},{"subj":"T9","pred":"source","obj":"DisGeNET"},{"subj":"T10","pred":"source","obj":"DisGeNET"},{"subj":"T11","pred":"source","obj":"DisGeNET"},{"subj":"T12","pred":"source","obj":"DisGeNET"},{"subj":"T13","pred":"source","obj":"DisGeNET"},{"subj":"T14","pred":"source","obj":"DisGeNET"},{"subj":"T15","pred":"source","obj":"DisGeNET"}]},{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":232,"end":247},"obj":"HP_0012125"},{"id":"T2","span":{"begin":241,"end":247},"obj":"HP_0002664"},{"id":"T3","span":{"begin":450,"end":465},"obj":"HP_0012125"},{"id":"T4","span":{"begin":459,"end":465},"obj":"HP_0002664"},{"id":"T5","span":{"begin":809,"end":824},"obj":"HP_0012125"},{"id":"T6","span":{"begin":818,"end":824},"obj":"HP_0002664"},{"id":"T7","span":{"begin":924,"end":929},"obj":"HP_0002664"},{"id":"T8","span":{"begin":1033,"end":1038},"obj":"HP_0002664"},{"id":"T9","span":{"begin":1280,"end":1295},"obj":"HP_0012125"},{"id":"T10","span":{"begin":1289,"end":1295},"obj":"HP_0002664"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"},{"subj":"T3","pred":"source","obj":"PubmedHPO"},{"subj":"T4","pred":"source","obj":"PubmedHPO"},{"subj":"T5","pred":"source","obj":"PubmedHPO"},{"subj":"T6","pred":"source","obj":"PubmedHPO"},{"subj":"T7","pred":"source","obj":"PubmedHPO"},{"subj":"T8","pred":"source","obj":"PubmedHPO"},{"subj":"T9","pred":"source","obj":"PubmedHPO"},{"subj":"T10","pred":"source","obj":"PubmedHPO"}]},{"project":"tmVarCorpus","denotations":[{"id":"T1","span":{"begin":401,"end":410},"obj":"ProteinMutation:p|SUB|I|462|V"},{"id":"T2","span":{"begin":415,"end":421},"obj":"DNAMutation:g|SUB|T|3801|C"}],"attributes":[{"subj":"T1","pred":"source","obj":"tmVarCorpus"},{"subj":"T2","pred":"source","obj":"tmVarCorpus"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubTator4TogoVar","color":"#a0ec93","default":true},{"id":"LitCoin-entities","color":"#ec93ba"},{"id":"LitCoin-sentences","color":"#93d4ec"},{"id":"LitCoin_Mondo","color":"#ece993"},{"id":"LitCoin-SeqVar","color":"#cf93ec"},{"id":"LitCoin-GeneOrGeneProduct-v0","color":"#93ecb5"},{"id":"LitCoin-GeneOrGeneProduct-v2","color":"#ec9b93"},{"id":"LitCoin-Disease-MeSH","color":"#93a4ec"},{"id":"LitCoin-GeneOrGeneProduct-v3","color":"#beec93"},{"id":"LitCoin_Mondo_095","color":"#ec93d8"},{"id":"LitCoin-MeSH-Disease-2","color":"#93ece6"},{"id":"LitCoin-MONDO_bioort2019","color":"#eccc93"},{"id":"LitCoin-Chemical-MeSH-CHEBI","color":"#b293ec"},{"id":"LitCoin-training-merged","color":"#93ec98"},{"id":"DisGeNET","color":"#ec93a8"},{"id":"PubmedHPO","color":"#93c2ec"},{"id":"tmVarCorpus","color":"#dcec93"}]}]}}