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PubMed:17192049 JSONTXT

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PubTator4TogoVar

Id Subject Object Predicate Lexical cue proteinmutation
17192049_0 401-410 ProteinMutation denotes Ile462Val rs1048943
17192049_1 721-728 ProteinMutation denotes Ile/Val rs1048943

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
3792 0-18 GeneOrGeneProduct denotes Cytochrome p4501A1 NCBIGene:1543
3793 62-77 DiseaseOrPhenotypicFeature denotes prostate cancer MESH:D011471
3794 79-85 GeneOrGeneProduct denotes CYP1A1 NCBIGene:1543
3795 232-247 DiseaseOrPhenotypicFeature denotes prostate cancer MESH:D011471
3796 339-345 SequenceVariant denotes A to G DBSNP:rs1048943
3797 401-410 SequenceVariant denotes Ile462Val DBSNP:rs1048943
3798 415-421 SequenceVariant denotes T3801C g|SUB|T|3801|C
3799 435-441 GeneOrGeneProduct denotes CYP1A1 NCBIGene:1543
3800 450-465 DiseaseOrPhenotypicFeature denotes prostate cancer MESH:D011471
3801 650-656 GeneOrGeneProduct denotes CYP1A1 NCBIGene:1543
3802 714-720 GeneOrGeneProduct denotes CYP1A1 NCBIGene:1543
3803 721-728 SequenceVariant denotes Ile/Val DBSNP:rs1048943
3804 809-824 DiseaseOrPhenotypicFeature denotes prostate cancer MESH:D011471
3805 924-929 DiseaseOrPhenotypicFeature denotes tumor MESH:D009369
3806 1033-1038 DiseaseOrPhenotypicFeature denotes tumor MESH:D009369
3807 1280-1295 DiseaseOrPhenotypicFeature denotes prostate cancer MESH:D011471

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-78 Sentence denotes Cytochrome p4501A1 gene variants as susceptibility marker for prostate cancer.
T2 79-248 Sentence denotes CYP1A1 activates environmental procarcinogens and catalyzes oxidative metabolism of estrogens and is likely to play an important role in the etiology of prostate cancer.
T3 249-550 Sentence denotes To evaluate this phenomenon, the association between two single nucleotide polymorphisms (A to G transition in exon7 leading to amino acid substitution Ile462Val and T3801C at 3'UTR) of CYP1A1 gene in prostate cancer were analyzed in a case-control study of 100 individuals in South Indian population.
T4 551-862 Sentence denotes The estimated relative risk was significantly high for individuals with w1/m1 genotype at 3'UTR of CYP1A1 gene (OR-4.64; 95%CI = 1.51-14.86; P < 0.01) whereas the CYP1A1 Ile/Val genotype (w2/m2) on exon 7 was found to be associated with a decreased risk for prostate cancer (OR-0.17; 95%CI = 0.02-0.89; P=0.03).
T5 863-1110 Sentence denotes A Stratified analysis of the genotypes with age of onset and tumor grade showed the w1/m1 genotype to be significantly associated with an early age of onset; however the tumor grades did not have significant association with the variant genotypes.
T6 1111-1296 Sentence denotes Thus the present study indicates that individuals with the variant w1/m1 genotype exhibit an increased risk while those with w2/m2 genotype exhibit a decreased risk for prostate cancer.

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 62-77 DiseaseOrPhenotypicFeature denotes prostate cancer 0008315
T2 71-77 DiseaseOrPhenotypicFeature denotes cancer 0004992
T3 232-247 DiseaseOrPhenotypicFeature denotes prostate cancer 0008315
T4 241-247 DiseaseOrPhenotypicFeature denotes cancer 0004992
T5 450-465 DiseaseOrPhenotypicFeature denotes prostate cancer 0008315
T6 459-465 DiseaseOrPhenotypicFeature denotes cancer 0004992
T7 809-824 DiseaseOrPhenotypicFeature denotes prostate cancer 0008315
T8 818-824 DiseaseOrPhenotypicFeature denotes cancer 0004992
T9 1280-1295 DiseaseOrPhenotypicFeature denotes prostate cancer 0008315
T10 1289-1295 DiseaseOrPhenotypicFeature denotes cancer 0004992

LitCoin-SeqVar

Id Subject Object Predicate Lexical cue
T1 401-410 SequenceVariant denotes Ile462Val
T2 415-421 SequenceVariant denotes T3801C

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 0-10 GeneOrGeneProduct denotes Cytochrome
T2 79-85 GeneOrGeneProduct denotes CYP1A1
T3 86-95 GeneOrGeneProduct denotes activates
T4 180-186 GeneOrGeneProduct denotes likely
T5 377-387 GeneOrGeneProduct denotes amino acid
T6 425-430 GeneOrGeneProduct denotes 3'UTR
T7 435-441 GeneOrGeneProduct denotes CYP1A1
T8 480-484 GeneOrGeneProduct denotes in a
T9 485-489 GeneOrGeneProduct denotes case
T10 597-601 GeneOrGeneProduct denotes high
T11 641-646 GeneOrGeneProduct denotes 3'UTR
T12 650-656 GeneOrGeneProduct denotes CYP1A1
T13 714-720 GeneOrGeneProduct denotes CYP1A1
T14 721-724 GeneOrGeneProduct denotes Ile
T15 739-741 GeneOrGeneProduct denotes w2
T16 924-929 GeneOrGeneProduct denotes tumor
T17 1001-1006 GeneOrGeneProduct denotes early
T18 1033-1038 GeneOrGeneProduct denotes tumor
T19 1236-1238 GeneOrGeneProduct denotes w2

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 0-10 GeneOrGeneProduct denotes Cytochrome
T2 79-85 GeneOrGeneProduct denotes CYP1A1
T3 377-387 GeneOrGeneProduct denotes amino acid
T4 425-430 GeneOrGeneProduct denotes 3'UTR
T5 435-441 GeneOrGeneProduct denotes CYP1A1
T6 597-601 GeneOrGeneProduct denotes high
T7 641-646 GeneOrGeneProduct denotes 3'UTR
T8 650-656 GeneOrGeneProduct denotes CYP1A1
T9 714-720 GeneOrGeneProduct denotes CYP1A1
T10 1001-1006 GeneOrGeneProduct denotes early

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 62-77 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T2 232-247 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T3 450-465 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T4 809-824 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T5 924-929 DiseaseOrPhenotypicFeature denotes tumor D009369
T6 1033-1038 DiseaseOrPhenotypicFeature denotes tumor D009369
T7 1280-1295 DiseaseOrPhenotypicFeature denotes prostate cancer D011471

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 0-10 GeneOrGeneProduct denotes Cytochrome
T2 79-85 GeneOrGeneProduct denotes CYP1A1
T3 435-441 GeneOrGeneProduct denotes CYP1A1
T4 650-656 GeneOrGeneProduct denotes CYP1A1
T5 714-720 GeneOrGeneProduct denotes CYP1A1

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 62-77 DiseaseOrPhenotypicFeature denotes prostate cancer 0008315
T2 232-247 DiseaseOrPhenotypicFeature denotes prostate cancer 0008315
T3 450-465 DiseaseOrPhenotypicFeature denotes prostate cancer 0008315
T4 809-824 DiseaseOrPhenotypicFeature denotes prostate cancer 0008315
T5 924-929 DiseaseOrPhenotypicFeature denotes tumor 0005070
T6 1033-1038 DiseaseOrPhenotypicFeature denotes tumor 0005070
T7 1280-1295 DiseaseOrPhenotypicFeature denotes prostate cancer 0008315

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 62-77 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T2 232-247 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T3 450-465 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T4 809-824 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T5 924-929 DiseaseOrPhenotypicFeature denotes tumor D009369
T6 1033-1038 DiseaseOrPhenotypicFeature denotes tumor D009369
T7 1280-1295 DiseaseOrPhenotypicFeature denotes prostate cancer D011471

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 62-77 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T2 232-247 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T3 450-465 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T4 809-824 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T5 924-929 DiseaseOrPhenotypicFeature denotes tumor D009369
T6 1033-1038 DiseaseOrPhenotypicFeature denotes tumor D009369
T7 1280-1295 DiseaseOrPhenotypicFeature denotes prostate cancer D011471

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 0-10 ChemicalEntity denotes Cytochrome http://purl.obolibrary.org/obo/CHEBI_4056
T2 721-728 ChemicalEntity denotes Ile/Val http://purl.obolibrary.org/obo/CHEBI_74327

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T2 721-728 ChemicalEntity denotes Ile/Val http://purl.obolibrary.org/obo/CHEBI_74327
T1 0-10 ChemicalEntity denotes Cytochrome http://purl.obolibrary.org/obo/CHEBI_4056
T5 714-720 GeneOrGeneProduct denotes CYP1A1
T4 650-656 GeneOrGeneProduct denotes CYP1A1
T3 435-441 GeneOrGeneProduct denotes CYP1A1
T56189 79-85 GeneOrGeneProduct denotes CYP1A1
T20753 0-10 GeneOrGeneProduct denotes Cytochrome
T7 1280-1295 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T6 1033-1038 DiseaseOrPhenotypicFeature denotes tumor D009369
T79632 924-929 DiseaseOrPhenotypicFeature denotes tumor D009369
T49358 809-824 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T11620 450-465 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T42149 232-247 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T55539 62-77 DiseaseOrPhenotypicFeature denotes prostate cancer D011471
T97576 415-421 SequenceVariant denotes T3801C
T16484 401-410 SequenceVariant denotes Ile462Val

DisGeNET

Id Subject Object Predicate Lexical cue
T0 643-646 gene:8170 denotes UTR
T1 809-824 disease:C0376358 denotes prostate cancer
T2 643-646 gene:8170 denotes UTR
T3 809-824 disease:C0600139 denotes prostate cancer
T4 643-646 gene:2837 denotes UTR
T5 809-824 disease:C0376358 denotes prostate cancer
T6 643-646 gene:2837 denotes UTR
T7 809-824 disease:C0600139 denotes prostate cancer
T8 650-656 gene:1543 denotes CYP1A1
T9 809-824 disease:C0376358 denotes prostate cancer
T10 650-656 gene:1543 denotes CYP1A1
T11 809-824 disease:C0600139 denotes prostate cancer
T12 714-720 gene:1543 denotes CYP1A1
T13 809-824 disease:C0376358 denotes prostate cancer
T14 714-720 gene:1543 denotes CYP1A1
T15 809-824 disease:C0600139 denotes prostate cancer
R1 T0 T1 associated_with UTR,prostate cancer
R2 T2 T3 associated_with UTR,prostate cancer
R3 T4 T5 associated_with UTR,prostate cancer
R4 T6 T7 associated_with UTR,prostate cancer
R5 T8 T9 associated_with CYP1A1,prostate cancer
R6 T10 T11 associated_with CYP1A1,prostate cancer
R7 T12 T13 associated_with CYP1A1,prostate cancer
R8 T14 T15 associated_with CYP1A1,prostate cancer

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 232-247 HP_0012125 denotes prostate cancer
T2 241-247 HP_0002664 denotes cancer
T3 450-465 HP_0012125 denotes prostate cancer
T4 459-465 HP_0002664 denotes cancer
T5 809-824 HP_0012125 denotes prostate cancer
T6 818-824 HP_0002664 denotes cancer
T7 924-929 HP_0002664 denotes tumor
T8 1033-1038 HP_0002664 denotes tumor
T9 1280-1295 HP_0012125 denotes prostate cancer
T10 1289-1295 HP_0002664 denotes cancer

tmVarCorpus

Id Subject Object Predicate Lexical cue
T1 401-410 ProteinMutation:p|SUB|I|462|V denotes Ile462Val
T2 415-421 DNAMutation:g|SUB|T|3801|C denotes T3801C