PubMed:17092940 / 1885-2149 JSONTXT

{"project":"GlyCosmos6-Glycan-Motif-Image","denotations":[{"id":"T10","span":{"begin":93,"end":95},"obj":"Glycan_Motif"}],"attributes":[{"id":"A10","pred":"image","subj":"T10","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00017MO"}],"text":"Taken together, our findings strongly suggest that N-WASP plays a pivotal role in regulating HA-mediated CD44-ErbB2 interaction, beta-catenin signaling, and actin cytoskeleton functions that are required for tumor-specific behaviors and ovarian cancer progression."}

{"project":"sentences","denotations":[{"id":"T9","span":{"begin":0,"end":264},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Taken together, our findings strongly suggest that N-WASP plays a pivotal role in regulating HA-mediated CD44-ErbB2 interaction, beta-catenin signaling, and actin cytoskeleton functions that are required for tumor-specific behaviors and ovarian cancer progression."}

{"project":"DisGeNET","denotations":[{"id":"T28","span":{"begin":110,"end":115},"obj":"gene:2064"},{"id":"T29","span":{"begin":237,"end":251},"obj":"disease:C1140680"},{"id":"T30","span":{"begin":110,"end":115},"obj":"gene:2064"},{"id":"T31","span":{"begin":237,"end":251},"obj":"disease:C0029925"}],"relations":[{"id":"R15","pred":"associated_with","subj":"T28","obj":"T29"},{"id":"R16","pred":"associated_with","subj":"T30","obj":"T31"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"text":"Taken together, our findings strongly suggest that N-WASP plays a pivotal role in regulating HA-mediated CD44-ErbB2 interaction, beta-catenin signaling, and actin cytoskeleton functions that are required for tumor-specific behaviors and ovarian cancer progression."}

{"project":"PubmedHPO","denotations":[{"id":"T6","span":{"begin":208,"end":213},"obj":"HP_0002664"},{"id":"T7","span":{"begin":237,"end":251},"obj":"HP_0100615"},{"id":"T8","span":{"begin":245,"end":251},"obj":"HP_0002664"},{"id":"T6","span":{"begin":208,"end":213},"obj":"HP_0002664"},{"id":"T7","span":{"begin":237,"end":251},"obj":"HP_0100615"},{"id":"T8","span":{"begin":245,"end":251},"obj":"HP_0002664"}],"text":"Taken together, our findings strongly suggest that N-WASP plays a pivotal role in regulating HA-mediated CD44-ErbB2 interaction, beta-catenin signaling, and actin cytoskeleton functions that are required for tumor-specific behaviors and ovarian cancer progression."}

{"project":"DisGeNET5_gene_disease","denotations":[{"id":"17092940-8#105#109#gene960","span":{"begin":105,"end":109},"obj":"gene960"},{"id":"17092940-8#110#115#gene2064","span":{"begin":110,"end":115},"obj":"gene2064"},{"id":"17092940-8#237#251#diseaseC0029925","span":{"begin":237,"end":251},"obj":"diseaseC0029925"},{"id":"17092940-8#237#251#diseaseC1140680","span":{"begin":237,"end":251},"obj":"diseaseC1140680"},{"id":"17092940-8#237#251#diseaseC0029925","span":{"begin":237,"end":251},"obj":"diseaseC0029925"},{"id":"17092940-8#237#251#diseaseC1140680","span":{"begin":237,"end":251},"obj":"diseaseC1140680"}],"relations":[{"id":"105#109#gene960237#251#diseaseC0029925","pred":"associated_with","subj":"17092940-8#105#109#gene960","obj":"17092940-8#237#251#diseaseC0029925"},{"id":"105#109#gene960237#251#diseaseC1140680","pred":"associated_with","subj":"17092940-8#105#109#gene960","obj":"17092940-8#237#251#diseaseC1140680"},{"id":"105#109#gene960237#251#diseaseC0029925","pred":"associated_with","subj":"17092940-8#105#109#gene960","obj":"17092940-8#237#251#diseaseC0029925"},{"id":"105#109#gene960237#251#diseaseC1140680","pred":"associated_with","subj":"17092940-8#105#109#gene960","obj":"17092940-8#237#251#diseaseC1140680"},{"id":"110#115#gene2064237#251#diseaseC0029925","pred":"associated_with","subj":"17092940-8#110#115#gene2064","obj":"17092940-8#237#251#diseaseC0029925"},{"id":"110#115#gene2064237#251#diseaseC1140680","pred":"associated_with","subj":"17092940-8#110#115#gene2064","obj":"17092940-8#237#251#diseaseC1140680"},{"id":"110#115#gene2064237#251#diseaseC0029925","pred":"associated_with","subj":"17092940-8#110#115#gene2064","obj":"17092940-8#237#251#diseaseC0029925"},{"id":"110#115#gene2064237#251#diseaseC1140680","pred":"associated_with","subj":"17092940-8#110#115#gene2064","obj":"17092940-8#237#251#diseaseC1140680"}],"text":"Taken together, our findings strongly suggest that N-WASP plays a pivotal role in regulating HA-mediated CD44-ErbB2 interaction, beta-catenin signaling, and actin cytoskeleton functions that are required for tumor-specific behaviors and ovarian cancer progression."}

{"project":"mondo_disease","denotations":[{"id":"T7","span":{"begin":208,"end":213},"obj":"Disease"},{"id":"T8","span":{"begin":237,"end":251},"obj":"Disease"}],"attributes":[{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005070"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0008170"}],"text":"Taken together, our findings strongly suggest that N-WASP plays a pivotal role in regulating HA-mediated CD44-ErbB2 interaction, beta-catenin signaling, and actin cytoskeleton functions that are required for tumor-specific behaviors and ovarian cancer progression."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T3","span":{"begin":157,"end":175},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/GO_0015629"}],"text":"Taken together, our findings strongly suggest that N-WASP plays a pivotal role in regulating HA-mediated CD44-ErbB2 interaction, beta-catenin signaling, and actin cytoskeleton functions that are required for tumor-specific behaviors and ovarian cancer progression."}

{"project":"GlyCosmos15-HP","denotations":[{"id":"T5","span":{"begin":208,"end":213},"obj":"Phenotype"},{"id":"T6","span":{"begin":237,"end":251},"obj":"Phenotype"}],"attributes":[{"id":"A5","pred":"hp_id","subj":"T5","obj":"HP:0002664"},{"id":"A6","pred":"hp_id","subj":"T6","obj":"HP:0100615"}],"namespaces":[{"prefix":"HP","uri":"http://purl.obolibrary.org/obo/HP_"}],"text":"Taken together, our findings strongly suggest that N-WASP plays a pivotal role in regulating HA-mediated CD44-ErbB2 interaction, beta-catenin signaling, and actin cytoskeleton functions that are required for tumor-specific behaviors and ovarian cancer progression."}