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LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-83 Sentence denotes Valproate-induced chorea and encephalopathy in atypical nonketotic hyperglycinemia.
T2 84-276 Sentence denotes Nonketotic hyperglycinemia is a disorder of amino acid metabolism in which a defect in the glycine cleavage system leads to an accumulation of glycine in the brain and other body compartments.
T3 277-415 Sentence denotes In the classical form it presents as neonatal apnea, intractable seizures, and hypotonia, followed by significant psychomotor retardation.
T4 416-540 Sentence denotes An important subset of children with nonketotic hyperglycinemia are atypical variants who present in a heterogeneous manner.
T5 541-781 Sentence denotes This report describes a patient with mild language delay and mental retardation, who was found to have nonketotic hyperglycinemia following her presentation with acute encephalopathy and chorea shortly after initiation of valproate therapy.

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
3621 565-572 OrganismTaxon denotes patient NCBITaxon:9606
3608 0-9 ChemicalEntity denotes Valproate MESH:D014635
3609 18-24 DiseaseOrPhenotypicFeature denotes chorea MESH:D002819
3610 29-43 DiseaseOrPhenotypicFeature denotes encephalopathy MESH:D001927
3611 56-82 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia MESH:D020158
3612 84-110 DiseaseOrPhenotypicFeature denotes Nonketotic hyperglycinemia MESH:D020158
3613 116-149 DiseaseOrPhenotypicFeature denotes disorder of amino acid metabolism MESH:D000592
3614 175-182 ChemicalEntity denotes glycine MESH:D005998
3615 227-234 ChemicalEntity denotes glycine MESH:D005998
3616 323-328 DiseaseOrPhenotypicFeature denotes apnea MESH:D001049
3617 342-350 DiseaseOrPhenotypicFeature denotes seizures MESH:D012640
3618 356-365 DiseaseOrPhenotypicFeature denotes hypotonia MESH:D009123
3619 391-414 DiseaseOrPhenotypicFeature denotes psychomotor retardation MESH:D011596
3620 453-479 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia MESH:D020158
3622 583-597 DiseaseOrPhenotypicFeature denotes language delay MESH:D007805
3623 602-620 DiseaseOrPhenotypicFeature denotes mental retardation MESH:D008607
3624 644-670 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia MESH:D020158
3625 709-723 DiseaseOrPhenotypicFeature denotes encephalopathy MESH:D001927
3626 728-734 DiseaseOrPhenotypicFeature denotes chorea MESH:D002819
3627 763-772 ChemicalEntity denotes valproate MESH:D014635

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 47-55 GeneOrGeneProduct denotes atypical
T2 56-82 GeneOrGeneProduct denotes nonketotic hyperglycinemia
T3 84-110 GeneOrGeneProduct denotes Nonketotic hyperglycinemia
T4 128-138 GeneOrGeneProduct denotes amino acid
T5 242-247 GeneOrGeneProduct denotes brain
T6 252-257 GeneOrGeneProduct denotes other
T7 342-350 GeneOrGeneProduct denotes seizures
T8 453-479 GeneOrGeneProduct denotes nonketotic hyperglycinemia
T9 484-492 GeneOrGeneProduct denotes atypical
T10 644-670 GeneOrGeneProduct denotes nonketotic hyperglycinemia

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 10-17 GeneOrGeneProduct denotes induced
T2 47-55 GeneOrGeneProduct denotes atypical
T3 56-82 GeneOrGeneProduct denotes nonketotic hyperglycinemia
T4 84-110 GeneOrGeneProduct denotes Nonketotic hyperglycinemia
T5 128-138 GeneOrGeneProduct denotes amino acid
T6 161-167 GeneOrGeneProduct denotes defect
T7 242-247 GeneOrGeneProduct denotes brain
T8 252-257 GeneOrGeneProduct denotes other
T9 342-350 GeneOrGeneProduct denotes seizures
T10 453-479 GeneOrGeneProduct denotes nonketotic hyperglycinemia
T11 484-492 GeneOrGeneProduct denotes atypical
T12 514-518 GeneOrGeneProduct denotes in a
T13 644-670 GeneOrGeneProduct denotes nonketotic hyperglycinemia
T14 749-759 GeneOrGeneProduct denotes initiation

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 18-24 DiseaseOrPhenotypicFeature denotes chorea D002819
T2 29-43 DiseaseOrPhenotypicFeature denotes encephalopathy D001927
T3 56-82 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia D020158
T4 84-110 DiseaseOrPhenotypicFeature denotes Nonketotic hyperglycinemia D020158
T5 323-328 DiseaseOrPhenotypicFeature denotes apnea D001049
T6 342-350 DiseaseOrPhenotypicFeature denotes seizures D012640
T7 356-365 DiseaseOrPhenotypicFeature denotes hypotonia D009123
T8 391-414 DiseaseOrPhenotypicFeature denotes psychomotor retardation DISEASE
T9 453-479 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia D020158
T10 583-597 DiseaseOrPhenotypicFeature denotes language delay D007805
T11 602-620 DiseaseOrPhenotypicFeature denotes mental retardation D008607
T12 644-670 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia D020158
T13 709-723 DiseaseOrPhenotypicFeature denotes encephalopathy D001927
T14 728-734 DiseaseOrPhenotypicFeature denotes chorea D002819

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 128-149 GeneOrGeneProduct denotes amino acid metabolism

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 47-82 DiseaseOrPhenotypicFeature denotes atypical nonketotic hyperglycinemia 0015010
T2 84-110 DiseaseOrPhenotypicFeature denotes Nonketotic hyperglycinemia 0011612
T3 116-149 DiseaseOrPhenotypicFeature denotes disorder of amino acid metabolism 0037871
T4 161-167 DiseaseOrPhenotypicFeature denotes defect 0008568
T5 453-479 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia 0011612
T6 602-620 DiseaseOrPhenotypicFeature denotes mental retardation 0001071
T7 644-670 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia 0011612

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 18-24 DiseaseOrPhenotypicFeature denotes chorea D002819
T2 29-43 DiseaseOrPhenotypicFeature denotes encephalopathy D001927
T3 56-82 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia D020158
T4 84-110 DiseaseOrPhenotypicFeature denotes Nonketotic hyperglycinemia D020158
T5 116-149 DiseaseOrPhenotypicFeature denotes disorder of amino acid metabolism DISEASE
T6 323-328 DiseaseOrPhenotypicFeature denotes apnea D001049
T7 342-350 DiseaseOrPhenotypicFeature denotes seizures D012640
T8 356-365 DiseaseOrPhenotypicFeature denotes hypotonia D009123
T9 391-414 DiseaseOrPhenotypicFeature denotes psychomotor retardation DISEASE
T10 453-479 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia D020158
T11 583-597 DiseaseOrPhenotypicFeature denotes language delay D007805
T12 602-620 DiseaseOrPhenotypicFeature denotes mental retardation D008607
T13 644-670 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia D020158
T14 709-723 DiseaseOrPhenotypicFeature denotes encephalopathy D001927
T15 728-734 DiseaseOrPhenotypicFeature denotes chorea D002819

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 18-24 DiseaseOrPhenotypicFeature denotes chorea D002819
T2 29-43 DiseaseOrPhenotypicFeature denotes encephalopathy D001927
T3 56-82 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia D020158
T4 84-110 DiseaseOrPhenotypicFeature denotes Nonketotic hyperglycinemia D020158
T5 116-149 DiseaseOrPhenotypicFeature denotes disorder of amino acid metabolism DISEASE
T6 323-328 DiseaseOrPhenotypicFeature denotes apnea D001049
T7 342-350 DiseaseOrPhenotypicFeature denotes seizures D012640
T8 356-365 DiseaseOrPhenotypicFeature denotes hypotonia D009123
T9 391-414 DiseaseOrPhenotypicFeature denotes psychomotor retardation DISEASE
T10 453-479 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia D020158
T11 583-597 DiseaseOrPhenotypicFeature denotes language delay D007805
T12 602-620 DiseaseOrPhenotypicFeature denotes mental retardation D008607
T13 644-670 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia D020158
T14 709-723 DiseaseOrPhenotypicFeature denotes encephalopathy D001927
T15 728-734 DiseaseOrPhenotypicFeature denotes chorea D002819

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 0-9 ChemicalEntity denotes Valproate D014635|http://purl.obolibrary.org/obo/CHEBI_60654
T3 175-198 ChemicalEntity denotes glycine cleavage system C064525
T4 227-234 ChemicalEntity denotes glycine http://purl.obolibrary.org/obo/CHEBI_57305|http://purl.obolibrary.org/obo/CHEBI_29947|http://purl.obolibrary.org/obo/CHEBI_15428
T7 763-772 ChemicalEntity denotes valproate D014635|http://purl.obolibrary.org/obo/CHEBI_60654

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 565-572 OrganismTaxon denotes patient

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T7 763-772 ChemicalEntity denotes valproate http://purl.obolibrary.org/obo/CHEBI_60654|D014635
T4 227-234 ChemicalEntity denotes glycine http://purl.obolibrary.org/obo/CHEBI_15428|http://purl.obolibrary.org/obo/CHEBI_29947|http://purl.obolibrary.org/obo/CHEBI_57305
T3 175-198 ChemicalEntity denotes glycine cleavage system C064525
T1 0-9 ChemicalEntity denotes Valproate http://purl.obolibrary.org/obo/CHEBI_60654|D014635
T30192 128-149 GeneOrGeneProduct denotes amino acid metabolism
T15 728-734 DiseaseOrPhenotypicFeature denotes chorea D002819
T14 709-723 DiseaseOrPhenotypicFeature denotes encephalopathy D001927
T13 644-670 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia D020158
T12 602-620 DiseaseOrPhenotypicFeature denotes mental retardation D008607
T11 583-597 DiseaseOrPhenotypicFeature denotes language delay D007805
T10 453-479 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia D020158
T9 391-414 DiseaseOrPhenotypicFeature denotes psychomotor retardation DISEASE
T8 356-365 DiseaseOrPhenotypicFeature denotes hypotonia D009123
T91145 342-350 DiseaseOrPhenotypicFeature denotes seizures D012640
T6 323-328 DiseaseOrPhenotypicFeature denotes apnea D001049
T5 116-149 DiseaseOrPhenotypicFeature denotes disorder of amino acid metabolism DISEASE
T11424 84-110 DiseaseOrPhenotypicFeature denotes Nonketotic hyperglycinemia D020158
T9389 56-82 DiseaseOrPhenotypicFeature denotes nonketotic hyperglycinemia D020158
T2 29-43 DiseaseOrPhenotypicFeature denotes encephalopathy D001927
T92845 18-24 DiseaseOrPhenotypicFeature denotes chorea D002819
T14241 565-572 OrganismTaxon denotes patient

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 84-110 HP_0008288 denotes Nonketotic hyperglycinemia
T2 95-110 HP_0002154 denotes hyperglycinemia
T3 116-149 HP_0004337 denotes disorder of amino acid metabolism
T4 128-167 HP_0004337 denotes amino acid metabolism in which a defect
T5 139-167 HP_0001939 denotes metabolism in which a defect
T6 139-182 HP_0010895 denotes metabolism in which a defect in the glycine
T7 323-328 HP_0002104 denotes apnea
T8 342-350 HP_0001250 denotes seizures
T9 356-365 HP_0001252 denotes hypotonia
T10 391-414 HP_0001263 denotes psychomotor retardation
T11 453-479 HP_0008288 denotes nonketotic hyperglycinemia
T12 464-479 HP_0002154 denotes hyperglycinemia
T13 583-597 HP_0000750 denotes language delay
T14 602-620 HP_0001249 denotes mental retardation
T15 644-670 HP_0008288 denotes nonketotic hyperglycinemia
T16 655-670 HP_0002154 denotes hyperglycinemia
T17 703-723 HP_0006846 denotes acute encephalopathy
T18 709-723 HP_0001298 denotes encephalopathy
T19 728-734 HP_0002072 denotes chorea

PubCasesHPO

Id Subject Object Predicate Lexical cue
AB1 84-110 HP:0008288 denotes Nonketotic hyperglycinemia
TI1 29-43 HP:0001298 denotes encephalopathy
TI2 56-82 HP:0008288 denotes nonketotic hyperglycinemia
AB2 323-328 HP:0002104 denotes apnea
AB3 342-350 HP:0001250 denotes seizures
AB4 453-479 HP:0008288 denotes nonketotic hyperglycinemia
AB5 644-670 HP:0008288 denotes nonketotic hyperglycinemia
AB6 703-723 HP:0006846 denotes acute encephalopathy
AB7 728-734 HP:0002072 denotes chorea