PubMed:16445950 / 1051-1377 JSONTXT

{"project":"Inflammaging","denotations":[{"id":"T8","span":{"begin":0,"end":326},"obj":"Sentence"},{"id":"T8","span":{"begin":0,"end":326},"obj":"Sentence"}],"text":"Our data suggest another possible explanation for the ability of Donepezil [diethyl(3,5-di-ter-butyl-4-hydroxybenzyl)phosphonate] to delay the progression of AD; in fact, Donepezil may modulate MCP-1 and IL-4 production, which may reflect a general shift towards type Th0/Th2 cytokines which could be protective in AD disease."}

{"project":"DisGeNET","denotations":[{"id":"T0","span":{"begin":194,"end":199},"obj":"gene:6347"},{"id":"T1","span":{"begin":315,"end":317},"obj":"disease:C0002395"},{"id":"T2","span":{"begin":204,"end":208},"obj":"gene:3565"},{"id":"T3","span":{"begin":315,"end":317},"obj":"disease:C0002395"}],"relations":[{"id":"R1","pred":"associated_with","subj":"T0","obj":"T1"},{"id":"R2","pred":"associated_with","subj":"T2","obj":"T3"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"text":"Our data suggest another possible explanation for the ability of Donepezil [diethyl(3,5-di-ter-butyl-4-hydroxybenzyl)phosphonate] to delay the progression of AD; in fact, Donepezil may modulate MCP-1 and IL-4 production, which may reflect a general shift towards type Th0/Th2 cytokines which could be protective in AD disease."}

{"project":"DisGeNET5_gene_disease","denotations":[{"id":"16445950-7#204#208#gene3565","span":{"begin":204,"end":208},"obj":"gene3565"},{"id":"16445950-7#315#317#diseaseC0002395","span":{"begin":315,"end":317},"obj":"diseaseC0002395"}],"relations":[{"id":"204#208#gene3565315#317#diseaseC0002395","pred":"associated_with","subj":"16445950-7#204#208#gene3565","obj":"16445950-7#315#317#diseaseC0002395"}],"text":"Our data suggest another possible explanation for the ability of Donepezil [diethyl(3,5-di-ter-butyl-4-hydroxybenzyl)phosphonate] to delay the progression of AD; in fact, Donepezil may modulate MCP-1 and IL-4 production, which may reflect a general shift towards type Th0/Th2 cytokines which could be protective in AD disease."}