PubMed:16428802
Annnotations
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1507-1512 | http://purl.obolibrary.org/obo/MAT_0000526 | denotes | colon |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1507-1519 | HP_0003003 | denotes | colon cancer |
| T2 | 1507-1519 | HP_0100273 | denotes | colon cancer |
| T3 | 1513-1519 | HP_0002664 | denotes | cancer |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 110-141 | http://www.uniprot.org/uniprot/Q06430 | denotes | N-acetylglucosaminyltransferase |
| T2 | 422-453 | http://www.uniprot.org/uniprot/Q06430 | denotes | N-acetylglucosaminyltransferase |
| T3 | 110-141 | http://www.uniprot.org/uniprot/Q8N0V5 | denotes | N-acetylglucosaminyltransferase |
| T4 | 422-453 | http://www.uniprot.org/uniprot/Q8N0V5 | denotes | N-acetylglucosaminyltransferase |
| T5 | 110-141 | http://www.uniprot.org/uniprot/Q8NFS9 | denotes | N-acetylglucosaminyltransferase |
| T6 | 422-453 | http://www.uniprot.org/uniprot/Q8NFS9 | denotes | N-acetylglucosaminyltransferase |
| T7 | 924-935 | http://www.uniprot.org/uniprot/P02787 | denotes | transferrin |
| T8 | 1147-1165 | http://www.uniprot.org/uniprot/P16278 | denotes | beta-galactosidase |
| T9 | 1248-1251 | http://www.uniprot.org/uniprot/P20132 | denotes | SDS |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 110-141 | http://www.uniprot.org/uniprot/P97402 | denotes | N-acetylglucosaminyltransferase |
| T2 | 422-453 | http://www.uniprot.org/uniprot/P97402 | denotes | N-acetylglucosaminyltransferase |
| T3 | 924-935 | http://www.uniprot.org/uniprot/Q63915 | denotes | transferrin |
| T4 | 1147-1165 | http://www.uniprot.org/uniprot/P23780 | denotes | beta-galactosidase |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1147-1151 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T2 | 1147-1151 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T3 | 1513-1519 | http://purl.bioontology.org/ontology/NCBITAXON/6754 | denotes | cancer |
| T4 | 1520-1525 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 110-144 | http://purl.obolibrary.org/obo/GO_0047253 | denotes | N-acetylglucosaminyltransferase VI |
| T2 | 422-456 | http://purl.obolibrary.org/obo/GO_0047253 | denotes | N-acetylglucosaminyltransferase VI |
| T3 | 207-220 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 236-240 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T2 | 1520-1525 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3 | 236-248 | http://purl.obolibrary.org/obo/GO_0009986 | denotes | cell surface |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1103-1108 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
| T2 | 1507-1512 | http://purl.obolibrary.org/obo/UBERON_0001155 | denotes | colon |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 357-363 | http://edamontology.org/topic_0154 | denotes | target |
| T2 | 708-713 | http://edamontology.org/topic_2815 | denotes | Human |
| T3 | 902-907 | http://edamontology.org/topic_2815 | denotes | human |
| T4 | 1083-1091 | http://edamontology.org/topic_0078 | denotes | proteins |
| T5 | 1097-1102 | http://edamontology.org/topic_2815 | denotes | human |
| T6 | 1367-1374 | http://edamontology.org/topic_0078 | denotes | protein |
| T7 | 1501-1506 | http://edamontology.org/topic_2815 | denotes | human |
| T8 | 1513-1519 | http://edamontology.org/topic_2640 | denotes | cancer |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 11-20 | http://edamontology.org/operation_2423 | denotes | detection |
| T2 | 341-352 | http://edamontology.org/data_2576 | denotes | To identify |
| T3 | 341-352 | http://edamontology.org/data_0977 | denotes | To identify |
| T4 | 344-352 | http://edamontology.org/data_2611 | denotes | identify |
| T5 | 344-352 | http://edamontology.org/data_0842 | denotes | identify |
| T6 | 612-621 | http://edamontology.org/data_0883 | denotes | structure |
| T7 | 612-625 | http://edamontology.org/operation_1848 | denotes | structure for |
| T8 | 756-759 | http://edamontology.org/format_3693 | denotes | AGP |
| T9 | 1006-1015 | http://edamontology.org/data_0883 | denotes | structure |
| T10 | 1083-1091 | http://edamontology.org/data_1467 | denotes | proteins |
| T11 | 1083-1091 | http://edamontology.org/format_1208 | denotes | proteins |
| T12 | 1175-1183 | http://edamontology.org/operation_2423 | denotes | detected |
| T13 | 1209-1219 | http://edamontology.org/data_2611 | denotes | identified |
| T14 | 1209-1219 | http://edamontology.org/data_0842 | denotes | identified |
| T15 | 1223-1226 | http://edamontology.org/format_3693 | denotes | AGP |
| T16 | 1258-1271 | http://edamontology.org/operation_2246 | denotes | demonstrating |
| T17 | 1358-1364 | http://edamontology.org/operation_2423 | denotes | detect |
| T18 | 1367-1374 | http://edamontology.org/format_1208 | denotes | protein |
| T19 | 1367-1374 | http://edamontology.org/data_1467 | denotes | protein |
NGLY1-deficiency
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-NGLY1-deficiency-B_T1 | 508-514 | chem:24139 | denotes | GlcNAc |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 16428802-7#130#133#gene3930 | 1457-1460 | gene3930 | denotes | PHA |
| 16428802-7#180#192#diseaseC0007102 | 1507-1519 | diseaseC0007102 | denotes | colon cancer |
| 16428802-7#180#192#diseaseC0699790 | 1507-1519 | diseaseC0699790 | denotes | colon cancer |
| 130#133#gene3930180#192#diseaseC0007102 | 16428802-7#130#133#gene3930 | 16428802-7#180#192#diseaseC0007102 | associated_with | PHA,colon cancer |
| 130#133#gene3930180#192#diseaseC0699790 | 16428802-7#130#133#gene3930 | 16428802-7#180#192#diseaseC0699790 | associated_with | PHA,colon cancer |
GlycoBiology-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1507-1512 | http://purl.obolibrary.org/obo/MAT_0000526 | denotes | colon |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-145 | Sentence | denotes | A specific detection of GlcNAcbeta1-6Manalpha1 branches in N-linked glycoproteins based on the specificity of N-acetylglucosaminyltransferase VI. |
| TextSentencer_T2 | 146-340 | Sentence | denotes | Malignant transformation is often accompanied by an aberrant glycosylation profile of the cell surface-in particular, the production of GlcNAcbeta1-6Manalpha1 branches in N-linked glycoproteins. |
| TextSentencer_T3 | 341-515 | Sentence | denotes | To identify the target glycoproteins, we show a method using recombinant chicken N-acetylglucosaminyltransferase VI (GnT VI) and radiolabeled uridine (5'-)diphosphate-GlcNAc. |
| TextSentencer_T4 | 516-707 | Sentence | denotes | The assay exploits the fact that GnT VI has a strict requirement for the GlcNAcbeta1-6Manalpha1 structure for activity, when a pyridylaminated free N-glycan is used as the acceptor substrate. |
| TextSentencer_T5 | 708-1074 | Sentence | denotes | Human asialo-agalacto alpha1-acid glycoprotein (AGP), which is known to contain GlcNAcbeta1-6Manalpha1 branches in its N-linked glycan chains, was radiolabeled when reacted with GnT VI, whereas human asialo-agalacto transferrin and bovine fetuin, neither of which contains a GlcNAcbeta1-6Manalpha1 structure were not, thus corroborating the specificity of the assay. |
| TextSentencer_T6 | 1075-1200 | Sentence | denotes | Several proteins from human serum after pretreatment with sialidase and beta-galactosidase could be detected using the assay. |
| TextSentencer_T7 | 1201-1326 | Sentence | denotes | One was identified as AGP from its mobility on SDS-PAGE, demonstrating the potential of this assay even with crude materials. |
| TextSentencer_T8 | 1327-1526 | Sentence | denotes | Furthermore, this method could detect a protein that was also positively stained with leukoagglutinating phytohemagglutinin (L(4)-PHA) using glycoproteins prepared from WiDr human colon cancer cells. |
| TextSentencer_T9 | 1527-1641 | Sentence | denotes | This method should provide a useful complement to the current method, which relies on the specificity of L(4)-PHA. |
| T1 | 0-145 | Sentence | denotes | A specific detection of GlcNAcbeta1-6Manalpha1 branches in N-linked glycoproteins based on the specificity of N-acetylglucosaminyltransferase VI. |
| T2 | 146-340 | Sentence | denotes | Malignant transformation is often accompanied by an aberrant glycosylation profile of the cell surface-in particular, the production of GlcNAcbeta1-6Manalpha1 branches in N-linked glycoproteins. |
| T3 | 341-515 | Sentence | denotes | To identify the target glycoproteins, we show a method using recombinant chicken N-acetylglucosaminyltransferase VI (GnT VI) and radiolabeled uridine (5'-)diphosphate-GlcNAc. |
| T4 | 516-707 | Sentence | denotes | The assay exploits the fact that GnT VI has a strict requirement for the GlcNAcbeta1-6Manalpha1 structure for activity, when a pyridylaminated free N-glycan is used as the acceptor substrate. |
| T5 | 708-1074 | Sentence | denotes | Human asialo-agalacto alpha1-acid glycoprotein (AGP), which is known to contain GlcNAcbeta1-6Manalpha1 branches in its N-linked glycan chains, was radiolabeled when reacted with GnT VI, whereas human asialo-agalacto transferrin and bovine fetuin, neither of which contains a GlcNAcbeta1-6Manalpha1 structure were not, thus corroborating the specificity of the assay. |
| T6 | 1075-1200 | Sentence | denotes | Several proteins from human serum after pretreatment with sialidase and beta-galactosidase could be detected using the assay. |
| T7 | 1201-1326 | Sentence | denotes | One was identified as AGP from its mobility on SDS-PAGE, demonstrating the potential of this assay even with crude materials. |
| T8 | 1327-1526 | Sentence | denotes | Furthermore, this method could detect a protein that was also positively stained with leukoagglutinating phytohemagglutinin (L(4)-PHA) using glycoproteins prepared from WiDr human colon cancer cells. |
| T9 | 1527-1641 | Sentence | denotes | This method should provide a useful complement to the current method, which relies on the specificity of L(4)-PHA. |
| T1 | 0-145 | Sentence | denotes | A specific detection of GlcNAcbeta1-6Manalpha1 branches in N-linked glycoproteins based on the specificity of N-acetylglucosaminyltransferase VI. |
| T2 | 146-340 | Sentence | denotes | Malignant transformation is often accompanied by an aberrant glycosylation profile of the cell surface-in particular, the production of GlcNAcbeta1-6Manalpha1 branches in N-linked glycoproteins. |
| T3 | 341-515 | Sentence | denotes | To identify the target glycoproteins, we show a method using recombinant chicken N-acetylglucosaminyltransferase VI (GnT VI) and radiolabeled uridine (5'-)diphosphate-GlcNAc. |
| T4 | 516-707 | Sentence | denotes | The assay exploits the fact that GnT VI has a strict requirement for the GlcNAcbeta1-6Manalpha1 structure for activity, when a pyridylaminated free N-glycan is used as the acceptor substrate. |
| T5 | 708-1074 | Sentence | denotes | Human asialo-agalacto alpha1-acid glycoprotein (AGP), which is known to contain GlcNAcbeta1-6Manalpha1 branches in its N-linked glycan chains, was radiolabeled when reacted with GnT VI, whereas human asialo-agalacto transferrin and bovine fetuin, neither of which contains a GlcNAcbeta1-6Manalpha1 structure were not, thus corroborating the specificity of the assay. |
| T6 | 1075-1200 | Sentence | denotes | Several proteins from human serum after pretreatment with sialidase and beta-galactosidase could be detected using the assay. |
| T7 | 1201-1326 | Sentence | denotes | One was identified as AGP from its mobility on SDS-PAGE, demonstrating the potential of this assay even with crude materials. |
| T8 | 1327-1526 | Sentence | denotes | Furthermore, this method could detect a protein that was also positively stained with leukoagglutinating phytohemagglutinin (L(4)-PHA) using glycoproteins prepared from WiDr human colon cancer cells. |
| T9 | 1527-1641 | Sentence | denotes | This method should provide a useful complement to the current method, which relies on the specificity of L(4)-PHA. |
GlycoBiology-Motifs
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 664-672 | http://rdf.glycoinfo.org/glycan/G00027MO | denotes | N-glycan |
GlyTouCan-IUPAC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| GlycanIUPAC_T1 | 508-514 | "http://rdf.glycoinfo.org/glycan/G26693XF" | denotes | GlcNAc |
| GlycanIUPAC_T2 | 508-514 | "http://rdf.glycoinfo.org/glycan/G01864SU" | denotes | GlcNAc |
| GlycanIUPAC_T3 | 508-514 | "http://rdf.glycoinfo.org/glycan/G17605FD" | denotes | GlcNAc |
| GlycanIUPAC_T4 | 508-514 | "http://rdf.glycoinfo.org/glycan/G41950LU" | denotes | GlcNAc |
| GlycanIUPAC_T5 | 508-514 | "http://rdf.glycoinfo.org/glycan/G57195RJ" | denotes | GlcNAc |
| GlycanIUPAC_T6 | 508-514 | "http://rdf.glycoinfo.org/glycan/G85391SA" | denotes | GlcNAc |
| GlycanIUPAC_T7 | 508-514 | "http://rdf.glycoinfo.org/glycan/G89565QL" | denotes | GlcNAc |
| GlycanIUPAC_T8 | 508-514 | "http://rdf.glycoinfo.org/glycan/G80869MR" | denotes | GlcNAc |
| GlycanIUPAC_T9 | 508-514 | "http://rdf.glycoinfo.org/glycan/G55978NL" | denotes | GlcNAc |
| GlycanIUPAC_T10 | 508-514 | "http://rdf.glycoinfo.org/glycan/G54644LT" | denotes | GlcNAc |
| GlycanIUPAC_T11 | 508-514 | "http://rdf.glycoinfo.org/glycan/G25694UG" | denotes | GlcNAc |
| GlycanIUPAC_T12 | 508-514 | "http://rdf.glycoinfo.org/glycan/G25126RB" | denotes | GlcNAc |
| GlycanIUPAC_T13 | 508-514 | "http://rdf.glycoinfo.org/glycan/G51848AD" | denotes | GlcNAc |
| GlycanIUPAC_T14 | 508-514 | "http://rdf.glycoinfo.org/glycan/G94667GM" | denotes | GlcNAc |
| GlycanIUPAC_T15 | 508-514 | "http://rdf.glycoinfo.org/glycan/G30124BO" | denotes | GlcNAc |
| GlycanIUPAC_T16 | 508-514 | "http://rdf.glycoinfo.org/glycan/G82777EZ" | denotes | GlcNAc |
| GlycanIUPAC_T17 | 508-514 | "http://rdf.glycoinfo.org/glycan/G10151YZ" | denotes | GlcNAc |
| GlycanIUPAC_T18 | 508-514 | "http://rdf.glycoinfo.org/glycan/G17585ZM" | denotes | GlcNAc |
| GlycanIUPAC_T19 | 508-514 | "http://rdf.glycoinfo.org/glycan/G04411CJ" | denotes | GlcNAc |
| GlycanIUPAC_T20 | 508-514 | "http://rdf.glycoinfo.org/glycan/G38254HJ" | denotes | GlcNAc |
| GlycanIUPAC_T21 | 508-514 | "http://rdf.glycoinfo.org/glycan/G75188FS" | denotes | GlcNAc |
| GlycanIUPAC_T22 | 508-514 | "http://rdf.glycoinfo.org/glycan/G70374VG" | denotes | GlcNAc |
| GlycanIUPAC_T23 | 508-514 | "http://rdf.glycoinfo.org/glycan/G45176LJ" | denotes | GlcNAc |
| GlycanIUPAC_T24 | 508-514 | "http://rdf.glycoinfo.org/glycan/G30874VW" | denotes | GlcNAc |
| GlycanIUPAC_T25 | 508-514 | "http://rdf.glycoinfo.org/glycan/G69333MI" | denotes | GlcNAc |
| GlycanIUPAC_T26 | 508-514 | "http://rdf.glycoinfo.org/glycan/G10676XO" | denotes | GlcNAc |
| GlycanIUPAC_T27 | 508-514 | "http://rdf.glycoinfo.org/glycan/G14843DJ" | denotes | GlcNAc |
| GlycanIUPAC_T28 | 508-514 | "http://rdf.glycoinfo.org/glycan/G47546FR" | denotes | GlcNAc |
| GlycanIUPAC_T29 | 508-514 | "http://rdf.glycoinfo.org/glycan/G73695ZM" | denotes | GlcNAc |
| GlycanIUPAC_T30 | 508-514 | "http://rdf.glycoinfo.org/glycan/G31923TJ" | denotes | GlcNAc |
| GlycanIUPAC_T31 | 508-514 | "http://rdf.glycoinfo.org/glycan/G60519EP" | denotes | GlcNAc |
| GlycanIUPAC_T32 | 508-514 | "http://rdf.glycoinfo.org/glycan/G07933IA" | denotes | GlcNAc |
| GlycanIUPAC_T33 | 508-514 | "http://rdf.glycoinfo.org/glycan/G40745NH" | denotes | GlcNAc |
| GlycanIUPAC_T34 | 508-514 | "http://rdf.glycoinfo.org/glycan/G54496YV" | denotes | GlcNAc |
| GlycanIUPAC_T35 | 508-514 | "http://rdf.glycoinfo.org/glycan/G62953SQ" | denotes | GlcNAc |
| GlycanIUPAC_T36 | 508-514 | "http://rdf.glycoinfo.org/glycan/G70070AY" | denotes | GlcNAc |
| GlycanIUPAC_T37 | 508-514 | "http://rdf.glycoinfo.org/glycan/G78792WC" | denotes | GlcNAc |
| GlycanIUPAC_T38 | 508-514 | "http://rdf.glycoinfo.org/glycan/G25238AV" | denotes | GlcNAc |
| GlycanIUPAC_T39 | 508-514 | "http://rdf.glycoinfo.org/glycan/G40510DP" | denotes | GlcNAc |
| GlycanIUPAC_T40 | 508-514 | "http://rdf.glycoinfo.org/glycan/G61120TK" | denotes | GlcNAc |
| GlycanIUPAC_T41 | 508-514 | "http://rdf.glycoinfo.org/glycan/G41342KV" | denotes | GlcNAc |
| GlycanIUPAC_T42 | 508-514 | "http://rdf.glycoinfo.org/glycan/G90703NA" | denotes | GlcNAc |
| GlycanIUPAC_T43 | 508-514 | "http://rdf.glycoinfo.org/glycan/G01591HR" | denotes | GlcNAc |
| GlycanIUPAC_T44 | 508-514 | "http://rdf.glycoinfo.org/glycan/G56520XN" | denotes | GlcNAc |
| GlycanIUPAC_T45 | 508-514 | "http://rdf.glycoinfo.org/glycan/G81830JX" | denotes | GlcNAc |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 1103-1108 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
| PD-UBERON-AE-B_T2 | 1507-1512 | http://purl.obolibrary.org/obo/UBERON_0001155 | denotes | colon |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 1457-1460 | gene:3930 | denotes | PHA |
| T1 | 1507-1519 | disease:C0007102 | denotes | colon cancer |
| T2 | 1457-1460 | gene:3930 | denotes | PHA |
| T3 | 1507-1519 | disease:C0699790 | denotes | colon cancer |
| R1 | T0 | T1 | associated_with | PHA,colon cancer |
| R2 | T2 | T3 | associated_with | PHA,colon cancer |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1507-1512 | Body_part | denotes | colon | http://purl.obolibrary.org/obo/MAT_0000526 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 1457-1460 | Disease | denotes | PHA | http://purl.obolibrary.org/obo/MONDO_0007710|http://purl.obolibrary.org/obo/MONDO_0008214 |
| T3 | 1507-1519 | Disease | denotes | colon cancer | http://purl.obolibrary.org/obo/MONDO_0021063 |
| T4 | 1637-1640 | Disease | denotes | PHA | http://purl.obolibrary.org/obo/MONDO_0007710|http://purl.obolibrary.org/obo/MONDO_0008214 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 708-713 | OrganismTaxon | denotes | Human | 9606 |
| T2 | 902-907 | OrganismTaxon | denotes | human | 9606 |
| T3 | 940-946 | OrganismTaxon | denotes | bovine | 9913 |
| T4 | 1097-1102 | OrganismTaxon | denotes | human | 9606 |
| T5 | 1501-1506 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1507-1512 | Body_part | denotes | colon | http://purl.obolibrary.org/obo/UBERON_0001155 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 1507-1519 | Phenotype | denotes | colon cancer | HP:0003003 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 1513-1525 | Cell | denotes | cancer cells | http://purl.obolibrary.org/obo/CL:0001064 |