PubMed:16364460 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/16364460","sourcedb":"PubMed","sourceid":"16364460","source_url":"https://www.ncbi.nlm.nih.gov/pubmed/16364460","text":"Microinjection of ritanserin into the CA1 region of hippocampus improves scopolamine-induced amnesia in adult male rats.\nThe effect of ritanserin (5-HT2 antagonist) on scopolamine (muscarinic cholinergic antagonist)-induced amnesia in Morris water maze (MWM) was investigated. Rats were divided into eight groups and bilaterally cannulated into CA1 region of the hippocampus. One week later, they received repeatedly vehicles (saline, DMSO, saline+DMSO), scopolamine (2 microg/0.5 microl saline/side; 30 min before training), ritanserin (2, 4 and 8 microg/0.5 microl DMSO/side; 20 min before training) and scopolamine (2 microg/0.5 microl; 30 min before ritanserin injection)+ritanserin (4 microg/0.5 microl DMSO) through cannulae each day. Animals were tested for four consecutive days (4 trial/day) in MWM during which the position of hidden platform was unchanged. In the fifth day, the platform was elevated above the water surface in another position to evaluate the function of motor, motivational and visual systems. The results showed a significant increase in escape latencies and traveled distances to find platform in scopolamine-treated group as compared to saline group. Ritanserin-treated rats (4 microg/0.5 microl/side) showed a significant decrease in the mentioned parameters as compared to DMSO-treated group. However, scopolamine and ritanserin co-administration resulted in a significant decrease in escape latencies and traveled distances as compared to the scopolamine-treated rats. Our findings show that microinjection of ritanserin into the CA1 region of the hippocampus improves the scopolamine-induced amnesia.","tracks":[{"project":"LitCoin-entities-OrganismTaxon-PD","denotations":[{"id":"T1","span":{"begin":52,"end":63},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":115,"end":119},"obj":"OrganismTaxon"},{"id":"T5","span":{"begin":277,"end":281},"obj":"OrganismTaxon"},{"id":"T8","span":{"begin":363,"end":374},"obj":"OrganismTaxon"},{"id":"T9","span":{"begin":1203,"end":1207},"obj":"OrganismTaxon"},{"id":"T12","span":{"begin":1499,"end":1503},"obj":"OrganismTaxon"},{"id":"T15","span":{"begin":1584,"end":1595},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"NCBItxid:72046"},{"id":"A2","pred":"db_id","subj":"T2","obj":"NCBItxid:10118"},{"id":"A3","pred":"db_id","subj":"T2","obj":"NCBItxid:10116"},{"id":"A4","pred":"db_id","subj":"T2","obj":"NCBItxid:10114"},{"id":"A5","pred":"db_id","subj":"T5","obj":"NCBItxid:10118"},{"id":"A6","pred":"db_id","subj":"T5","obj":"NCBItxid:10116"},{"id":"A7","pred":"db_id","subj":"T5","obj":"NCBItxid:10114"},{"id":"A8","pred":"db_id","subj":"T8","obj":"NCBItxid:72046"},{"id":"A9","pred":"db_id","subj":"T9","obj":"NCBItxid:10118"},{"id":"A10","pred":"db_id","subj":"T9","obj":"NCBItxid:10116"},{"id":"A11","pred":"db_id","subj":"T9","obj":"NCBItxid:10114"},{"id":"A12","pred":"db_id","subj":"T12","obj":"NCBItxid:10118"},{"id":"A13","pred":"db_id","subj":"T12","obj":"NCBItxid:10116"},{"id":"A14","pred":"db_id","subj":"T12","obj":"NCBItxid:10114"},{"id":"A15","pred":"db_id","subj":"T15","obj":"NCBItxid:72046"},{"subj":"T1","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T2","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T5","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T8","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T9","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T12","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T15","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"}]},{"project":"LitCoin-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":120},"obj":"Sentence"},{"id":"T2","span":{"begin":121,"end":276},"obj":"Sentence"},{"id":"T3","span":{"begin":277,"end":375},"obj":"Sentence"},{"id":"T4","span":{"begin":376,"end":740},"obj":"Sentence"},{"id":"T5","span":{"begin":741,"end":867},"obj":"Sentence"},{"id":"T6","span":{"begin":868,"end":1023},"obj":"Sentence"},{"id":"T7","span":{"begin":1024,"end":1183},"obj":"Sentence"},{"id":"T8","span":{"begin":1184,"end":1327},"obj":"Sentence"},{"id":"T9","span":{"begin":1328,"end":1504},"obj":"Sentence"},{"id":"T10","span":{"begin":1505,"end":1637},"obj":"Sentence"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-sentences"},{"subj":"T2","pred":"source","obj":"LitCoin-sentences"},{"subj":"T3","pred":"source","obj":"LitCoin-sentences"},{"subj":"T4","pred":"source","obj":"LitCoin-sentences"},{"subj":"T5","pred":"source","obj":"LitCoin-sentences"},{"subj":"T6","pred":"source","obj":"LitCoin-sentences"},{"subj":"T7","pred":"source","obj":"LitCoin-sentences"},{"subj":"T8","pred":"source","obj":"LitCoin-sentences"},{"subj":"T9","pred":"source","obj":"LitCoin-sentences"},{"subj":"T10","pred":"source","obj":"LitCoin-sentences"}]},{"project":"LitCoin-entities","denotations":[{"id":"2604","span":{"begin":18,"end":28},"obj":"ChemicalEntity"},{"id":"2605","span":{"begin":73,"end":84},"obj":"ChemicalEntity"},{"id":"2606","span":{"begin":93,"end":100},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2607","span":{"begin":115,"end":119},"obj":"OrganismTaxon"},{"id":"2608","span":{"begin":135,"end":145},"obj":"ChemicalEntity"},{"id":"2609","span":{"begin":147,"end":152},"obj":"GeneOrGeneProduct"},{"id":"2610","span":{"begin":168,"end":179},"obj":"ChemicalEntity"},{"id":"2611","span":{"begin":181,"end":203},"obj":"GeneOrGeneProduct"},{"id":"2612","span":{"begin":224,"end":231},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2613","span":{"begin":277,"end":281},"obj":"OrganismTaxon"},{"id":"2614","span":{"begin":435,"end":439},"obj":"ChemicalEntity"},{"id":"2615","span":{"begin":448,"end":452},"obj":"ChemicalEntity"},{"id":"2616","span":{"begin":455,"end":466},"obj":"ChemicalEntity"},{"id":"2617","span":{"begin":526,"end":536},"obj":"ChemicalEntity"},{"id":"2618","span":{"begin":567,"end":571},"obj":"ChemicalEntity"},{"id":"2619","span":{"begin":606,"end":617},"obj":"ChemicalEntity"},{"id":"2620","span":{"begin":654,"end":664},"obj":"ChemicalEntity"},{"id":"2621","span":{"begin":676,"end":686},"obj":"ChemicalEntity"},{"id":"2622","span":{"begin":708,"end":712},"obj":"ChemicalEntity"},{"id":"2623","span":{"begin":1129,"end":1140},"obj":"ChemicalEntity"},{"id":"2624","span":{"begin":1184,"end":1194},"obj":"ChemicalEntity"},{"id":"2625","span":{"begin":1203,"end":1207},"obj":"OrganismTaxon"},{"id":"2626","span":{"begin":1308,"end":1312},"obj":"ChemicalEntity"},{"id":"2627","span":{"begin":1337,"end":1348},"obj":"ChemicalEntity"},{"id":"2628","span":{"begin":1353,"end":1363},"obj":"ChemicalEntity"},{"id":"2629","span":{"begin":1479,"end":1490},"obj":"ChemicalEntity"},{"id":"2630","span":{"begin":1499,"end":1503},"obj":"OrganismTaxon"},{"id":"2631","span":{"begin":1546,"end":1556},"obj":"ChemicalEntity"},{"id":"2632","span":{"begin":1609,"end":1620},"obj":"ChemicalEntity"},{"id":"2633","span":{"begin":1629,"end":1636},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A12","pred":"db_id","subj":"2615","obj":"MESH:D004121"},{"id":"A19","pred":"db_id","subj":"2622","obj":"MESH:D004121"},{"id":"A23","pred":"db_id","subj":"2626","obj":"MESH:D004121"},{"id":"A8","pred":"db_id","subj":"2611","obj":"NCBIGene:25229"},{"id":"A10","pred":"db_id","subj":"2613","obj":"NCBITaxon:10116"},{"id":"A7","pred":"db_id","subj":"2610","obj":"MESH:D012601"},{"id":"A24","pred":"db_id","subj":"2627","obj":"MESH:D012601"},{"id":"A5","pred":"db_id","subj":"2608","obj":"MESH:D016713"},{"id":"A6","pred":"db_id","subj":"2609","obj":"NCBIGene:29595"},{"id":"A3","pred":"db_id","subj":"2606","obj":"MESH:D000647"},{"id":"A1","pred":"db_id","subj":"2604","obj":"MESH:D016713"},{"id":"A25","pred":"db_id","subj":"2628","obj":"MESH:D016713"},{"id":"A16","pred":"db_id","subj":"2619","obj":"MESH:D012601"},{"id":"A2","pred":"db_id","subj":"2605","obj":"MESH:D012601"},{"id":"A11","pred":"db_id","subj":"2614","obj":"MESH:D004121"},{"id":"A27","pred":"db_id","subj":"2630","obj":"NCBITaxon:10116"},{"id":"A30","pred":"db_id","subj":"2633","obj":"MESH:D000647"},{"id":"A4","pred":"db_id","subj":"2607","obj":"NCBITaxon:10116"},{"id":"A15","pred":"db_id","subj":"2618","obj":"MESH:D004121"},{"id":"A21","pred":"db_id","subj":"2624","obj":"MESH:D016713"},{"id":"A26","pred":"db_id","subj":"2629","obj":"MESH:D012601"},{"id":"A17","pred":"db_id","subj":"2620","obj":"MESH:D016713"},{"id":"A14","pred":"db_id","subj":"2617","obj":"MESH:D016713"},{"id":"A29","pred":"db_id","subj":"2632","obj":"MESH:D012601"},{"id":"A20","pred":"db_id","subj":"2623","obj":"MESH:D012601"},{"id":"A28","pred":"db_id","subj":"2631","obj":"MESH:D016713"},{"id":"A13","pred":"db_id","subj":"2616","obj":"MESH:D012601"},{"id":"A22","pred":"db_id","subj":"2625","obj":"NCBITaxon:10116"},{"id":"A18","pred":"db_id","subj":"2621","obj":"MESH:D016713"},{"id":"A9","pred":"db_id","subj":"2612","obj":"MESH:D000647"},{"subj":"2604","pred":"source","obj":"LitCoin-entities"},{"subj":"2605","pred":"source","obj":"LitCoin-entities"},{"subj":"2606","pred":"source","obj":"LitCoin-entities"},{"subj":"2607","pred":"source","obj":"LitCoin-entities"},{"subj":"2608","pred":"source","obj":"LitCoin-entities"},{"subj":"2609","pred":"source","obj":"LitCoin-entities"},{"subj":"2610","pred":"source","obj":"LitCoin-entities"},{"subj":"2611","pred":"source","obj":"LitCoin-entities"},{"subj":"2612","pred":"source","obj":"LitCoin-entities"},{"subj":"2613","pred":"source","obj":"LitCoin-entities"},{"subj":"2614","pred":"source","obj":"LitCoin-entities"},{"subj":"2615","pred":"source","obj":"LitCoin-entities"},{"subj":"2616","pred":"source","obj":"LitCoin-entities"},{"subj":"2617","pred":"source","obj":"LitCoin-entities"},{"subj":"2618","pred":"source","obj":"LitCoin-entities"},{"subj":"2619","pred":"source","obj":"LitCoin-entities"},{"subj":"2620","pred":"source","obj":"LitCoin-entities"},{"subj":"2621","pred":"source","obj":"LitCoin-entities"},{"subj":"2622","pred":"source","obj":"LitCoin-entities"},{"subj":"2623","pred":"source","obj":"LitCoin-entities"},{"subj":"2624","pred":"source","obj":"LitCoin-entities"},{"subj":"2625","pred":"source","obj":"LitCoin-entities"},{"subj":"2626","pred":"source","obj":"LitCoin-entities"},{"subj":"2627","pred":"source","obj":"LitCoin-entities"},{"subj":"2628","pred":"source","obj":"LitCoin-entities"},{"subj":"2629","pred":"source","obj":"LitCoin-entities"},{"subj":"2630","pred":"source","obj":"LitCoin-entities"},{"subj":"2631","pred":"source","obj":"LitCoin-entities"},{"subj":"2632","pred":"source","obj":"LitCoin-entities"},{"subj":"2633","pred":"source","obj":"LitCoin-entities"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}]},{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T1","span":{"begin":147,"end":152},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":495,"end":499},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":572,"end":576},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":928,"end":935},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":984,"end":989},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":1229,"end":1233},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"}]},{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T1","span":{"begin":38,"end":41},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":85,"end":92},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":110,"end":114},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":147,"end":152},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":153,"end":163},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":204,"end":214},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":216,"end":223},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":248,"end":252},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":345,"end":348},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":385,"end":390},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":495,"end":499},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":541,"end":546},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":572,"end":576},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":754,"end":760},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":928,"end":935},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":984,"end":989},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":1112,"end":1116},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":1229,"end":1233},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":1391,"end":1395},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":1509,"end":1517},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":1566,"end":1569},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":1621,"end":1628},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T21","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T22","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"}]},{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T1","span":{"begin":93,"end":100},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":224,"end":231},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":1629,"end":1636},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"originalLabel","subj":"T1","obj":"D000647"},{"id":"A2","pred":"originalLabel","subj":"T2","obj":"D000647"},{"id":"A3","pred":"originalLabel","subj":"T3","obj":"D000647"},{"subj":"T1","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T2","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T3","pred":"source","obj":"LitCoin-Disease-MeSH"}]},{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T1","span":{"begin":147,"end":152},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"}]},{"project":"LitCoin_Mondo_095","denotations":[{"id":"T1","span":{"begin":93,"end":100},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":224,"end":231},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":1629,"end":1636},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0001152"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0001152"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0001152"},{"subj":"T1","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T2","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T3","pred":"source","obj":"LitCoin_Mondo_095"}]},{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T1","span":{"begin":93,"end":100},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":224,"end":231},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":1629,"end":1636},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"ID:","subj":"T1","obj":"D000647"},{"id":"A2","pred":"ID:","subj":"T2","obj":"D000647"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D000647"},{"subj":"T1","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T2","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T3","pred":"source","obj":"LitCoin-MeSH-Disease-2"}]},{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T1","span":{"begin":93,"end":100},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":224,"end":231},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":1629,"end":1636},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"#label","subj":"T1","obj":"D000647"},{"id":"A2","pred":"#label","subj":"T2","obj":"D000647"},{"id":"A3","pred":"#label","subj":"T3","obj":"D000647"},{"subj":"T1","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T2","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T3","pred":"source","obj":"LitCoin-MONDO_bioort2019"}]},{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T1","span":{"begin":18,"end":28},"obj":"ChemicalEntity"},{"id":"T3","span":{"begin":73,"end":84},"obj":"ChemicalEntity"},{"id":"T5","span":{"begin":135,"end":145},"obj":"ChemicalEntity"},{"id":"T7","span":{"begin":168,"end":179},"obj":"ChemicalEntity"},{"id":"T9","span":{"begin":242,"end":247},"obj":"ChemicalEntity"},{"id":"T11","span":{"begin":435,"end":439},"obj":"ChemicalEntity"},{"id":"T13","span":{"begin":448,"end":452},"obj":"ChemicalEntity"},{"id":"T15","span":{"begin":455,"end":466},"obj":"ChemicalEntity"},{"id":"T17","span":{"begin":526,"end":536},"obj":"ChemicalEntity"},{"id":"T19","span":{"begin":567,"end":571},"obj":"ChemicalEntity"},{"id":"T21","span":{"begin":606,"end":617},"obj":"ChemicalEntity"},{"id":"T23","span":{"begin":654,"end":664},"obj":"ChemicalEntity"},{"id":"T25","span":{"begin":676,"end":686},"obj":"ChemicalEntity"},{"id":"T27","span":{"begin":708,"end":712},"obj":"ChemicalEntity"},{"id":"T29","span":{"begin":922,"end":927},"obj":"ChemicalEntity"},{"id":"T31","span":{"begin":1129,"end":1140},"obj":"ChemicalEntity"},{"id":"T33","span":{"begin":1184,"end":1194},"obj":"ChemicalEntity"},{"id":"T35","span":{"begin":1308,"end":1312},"obj":"ChemicalEntity"},{"id":"T37","span":{"begin":1337,"end":1348},"obj":"ChemicalEntity"},{"id":"T39","span":{"begin":1353,"end":1363},"obj":"ChemicalEntity"},{"id":"T41","span":{"begin":1479,"end":1490},"obj":"ChemicalEntity"},{"id":"T43","span":{"begin":1546,"end":1556},"obj":"ChemicalEntity"},{"id":"T45","span":{"begin":1609,"end":1620},"obj":"ChemicalEntity"}],"attributes":[{"id":"A31","pred":"ID:","subj":"T31","obj":"D012601"},{"id":"A32","pred":"ID:","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A33","pred":"ID:","subj":"T33","obj":"D016713"},{"id":"A34","pred":"ID:","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A23","pred":"ID:","subj":"T23","obj":"D016713"},{"id":"A24","pred":"ID:","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D012601"},{"id":"A4","pred":"ID:","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A35","pred":"ID:","subj":"T35","obj":"D004121"},{"id":"A36","pred":"ID:","subj":"T35","obj":"http://purl.obolibrary.org/obo/CHEBI_28262"},{"id":"A41","pred":"ID:","subj":"T41","obj":"D012601"},{"id":"A42","pred":"ID:","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A19","pred":"ID:","subj":"T19","obj":"D004121"},{"id":"A20","pred":"ID:","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_28262"},{"id":"A27","pred":"ID:","subj":"T27","obj":"D004121"},{"id":"A28","pred":"ID:","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_28262"},{"id":"A29","pred":"ID:","subj":"T29","obj":"D014867"},{"id":"A30","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A9","pred":"ID:","subj":"T9","obj":"D014867"},{"id":"A10","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A39","pred":"ID:","subj":"T39","obj":"D016713"},{"id":"A40","pred":"ID:","subj":"T39","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A7","pred":"ID:","subj":"T7","obj":"D012601"},{"id":"A8","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A1","pred":"ID:","subj":"T1","obj":"D016713"},{"id":"A2","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A15","pred":"ID:","subj":"T15","obj":"D012601"},{"id":"A16","pred":"ID:","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A43","pred":"ID:","subj":"T43","obj":"D016713"},{"id":"A44","pred":"ID:","subj":"T43","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A25","pred":"ID:","subj":"T25","obj":"D016713"},{"id":"A26","pred":"ID:","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A45","pred":"ID:","subj":"T45","obj":"D012601"},{"id":"A46","pred":"ID:","subj":"T45","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A11","pred":"ID:","subj":"T11","obj":"D004121"},{"id":"A12","pred":"ID:","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_28262"},{"id":"A5","pred":"ID:","subj":"T5","obj":"D016713"},{"id":"A6","pred":"ID:","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A13","pred":"ID:","subj":"T13","obj":"D004121"},{"id":"A14","pred":"ID:","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_28262"},{"id":"A21","pred":"ID:","subj":"T21","obj":"D012601"},{"id":"A22","pred":"ID:","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A17","pred":"ID:","subj":"T17","obj":"D016713"},{"id":"A18","pred":"ID:","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A37","pred":"ID:","subj":"T37","obj":"D012601"},{"id":"A38","pred":"ID:","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"subj":"T1","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T3","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T5","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T7","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T9","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T11","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T13","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T15","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T17","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T19","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T21","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T23","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T25","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T27","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T29","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T31","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T33","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T35","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T37","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T39","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T41","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T43","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T45","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"}]},{"project":"LitCoin-NCBITaxon-2","denotations":[{"id":"T1","span":{"begin":115,"end":119},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":277,"end":281},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":1203,"end":1207},"obj":"OrganismTaxon"},{"id":"T4","span":{"begin":1499,"end":1503},"obj":"OrganismTaxon"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-NCBITaxon-2"},{"subj":"T2","pred":"source","obj":"LitCoin-NCBITaxon-2"},{"subj":"T3","pred":"source","obj":"LitCoin-NCBITaxon-2"},{"subj":"T4","pred":"source","obj":"LitCoin-NCBITaxon-2"}]},{"project":"LitCoin-training-merged","denotations":[{"id":"T45","span":{"begin":1609,"end":1620},"obj":"ChemicalEntity"},{"id":"T43","span":{"begin":1546,"end":1556},"obj":"ChemicalEntity"},{"id":"T41","span":{"begin":1479,"end":1490},"obj":"ChemicalEntity"},{"id":"T39","span":{"begin":1353,"end":1363},"obj":"ChemicalEntity"},{"id":"T37","span":{"begin":1337,"end":1348},"obj":"ChemicalEntity"},{"id":"T35","span":{"begin":1308,"end":1312},"obj":"ChemicalEntity"},{"id":"T33","span":{"begin":1184,"end":1194},"obj":"ChemicalEntity"},{"id":"T31","span":{"begin":1129,"end":1140},"obj":"ChemicalEntity"},{"id":"T29","span":{"begin":922,"end":927},"obj":"ChemicalEntity"},{"id":"T27","span":{"begin":708,"end":712},"obj":"ChemicalEntity"},{"id":"T25","span":{"begin":676,"end":686},"obj":"ChemicalEntity"},{"id":"T23","span":{"begin":654,"end":664},"obj":"ChemicalEntity"},{"id":"T21","span":{"begin":606,"end":617},"obj":"ChemicalEntity"},{"id":"T19","span":{"begin":567,"end":571},"obj":"ChemicalEntity"},{"id":"T17","span":{"begin":526,"end":536},"obj":"ChemicalEntity"},{"id":"T15","span":{"begin":455,"end":466},"obj":"ChemicalEntity"},{"id":"T13","span":{"begin":448,"end":452},"obj":"ChemicalEntity"},{"id":"T11","span":{"begin":435,"end":439},"obj":"ChemicalEntity"},{"id":"T9","span":{"begin":242,"end":247},"obj":"ChemicalEntity"},{"id":"T7","span":{"begin":168,"end":179},"obj":"ChemicalEntity"},{"id":"T5","span":{"begin":135,"end":145},"obj":"ChemicalEntity"},{"id":"T3","span":{"begin":73,"end":84},"obj":"ChemicalEntity"},{"id":"T1","span":{"begin":18,"end":28},"obj":"ChemicalEntity"},{"id":"T843","span":{"begin":147,"end":152},"obj":"GeneOrGeneProduct"},{"id":"T90807","span":{"begin":1629,"end":1636},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":224,"end":231},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T60369","span":{"begin":93,"end":100},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":1499,"end":1503},"obj":"OrganismTaxon"},{"id":"T88593","span":{"begin":1203,"end":1207},"obj":"OrganismTaxon"},{"id":"T60347","span":{"begin":277,"end":281},"obj":"OrganismTaxon"},{"id":"T24525","span":{"begin":115,"end":119},"obj":"OrganismTaxon"}],"attributes":[{"id":"A42","pred":"ID:","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A41","pred":"ID:","subj":"T41","obj":"D012601"},{"id":"A2","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A1","pred":"ID:","subj":"T1","obj":"D016713"},{"id":"A44","pred":"ID:","subj":"T43","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A43","pred":"ID:","subj":"T43","obj":"D016713"},{"id":"A39422","pred":"#label","subj":"T2","obj":"D000647"},{"id":"A16","pred":"ID:","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A15","pred":"ID:","subj":"T15","obj":"D012601"},{"id":"A38","pred":"ID:","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A37","pred":"ID:","subj":"T37","obj":"D012601"},{"id":"A22","pred":"ID:","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A21","pred":"ID:","subj":"T21","obj":"D012601"},{"id":"A18","pred":"ID:","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A17","pred":"ID:","subj":"T17","obj":"D016713"},{"id":"A30","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A29","pred":"ID:","subj":"T29","obj":"D014867"},{"id":"A12","pred":"ID:","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_28262"},{"id":"A11","pred":"ID:","subj":"T11","obj":"D004121"},{"id":"A83292","pred":"#label","subj":"T90807","obj":"D000647"},{"id":"A36","pred":"ID:","subj":"T35","obj":"http://purl.obolibrary.org/obo/CHEBI_28262"},{"id":"A35","pred":"ID:","subj":"T35","obj":"D004121"},{"id":"A14","pred":"ID:","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_28262"},{"id":"A13","pred":"ID:","subj":"T13","obj":"D004121"},{"id":"A34","pred":"ID:","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A33","pred":"ID:","subj":"T33","obj":"D016713"},{"id":"A32","pred":"ID:","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A31","pred":"ID:","subj":"T31","obj":"D012601"},{"id":"A10","pred":"ID:","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A9","pred":"ID:","subj":"T9","obj":"D014867"},{"id":"A8","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A7","pred":"ID:","subj":"T7","obj":"D012601"},{"id":"A40","pred":"ID:","subj":"T39","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A39","pred":"ID:","subj":"T39","obj":"D016713"},{"id":"A24","pred":"ID:","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A23","pred":"ID:","subj":"T23","obj":"D016713"},{"id":"A4","pred":"ID:","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D012601"},{"id":"A28084","pred":"#label","subj":"T60369","obj":"D000647"},{"id":"A26","pred":"ID:","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A25","pred":"ID:","subj":"T25","obj":"D016713"},{"id":"A46","pred":"ID:","subj":"T45","obj":"http://purl.obolibrary.org/obo/CHEBI_16794"},{"id":"A45","pred":"ID:","subj":"T45","obj":"D012601"},{"id":"A6","pred":"ID:","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_64195"},{"id":"A5","pred":"ID:","subj":"T5","obj":"D016713"},{"id":"A20","pred":"ID:","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_28262"},{"id":"A19","pred":"ID:","subj":"T19","obj":"D004121"},{"id":"A28","pred":"ID:","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_28262"},{"id":"A27","pred":"ID:","subj":"T27","obj":"D004121"},{"subj":"T45","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T43","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T41","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T39","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T37","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T35","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T33","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T31","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T29","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T27","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T25","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T23","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T21","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T19","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T17","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T15","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T13","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T11","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T9","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T7","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T5","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T3","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T1","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T843","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T90807","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T2","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T60369","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T4","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T88593","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T60347","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T24525","pred":"source","obj":"LitCoin-training-merged"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCoin-entities-OrganismTaxon-PD","color":"#93ece1","default":true},{"id":"LitCoin-sentences","color":"#ecc793"},{"id":"LitCoin-entities","color":"#ad93ec"},{"id":"LitCoin-GeneOrGeneProduct-v2","color":"#93ec93"},{"id":"LitCoin-GeneOrGeneProduct-v0","color":"#ec93ac"},{"id":"LitCoin-Disease-MeSH","color":"#93c6ec"},{"id":"LitCoin-GeneOrGeneProduct-v3","color":"#e0ec93"},{"id":"LitCoin_Mondo_095","color":"#de93ec"},{"id":"LitCoin-MeSH-Disease-2","color":"#93ecc4"},{"id":"LitCoin-MONDO_bioort2019","color":"#ecaa93"},{"id":"LitCoin-Chemical-MeSH-CHEBI","color":"#9396ec"},{"id":"LitCoin-NCBITaxon-2","color":"#b0ec93"},{"id":"LitCoin-training-merged","color":"#ec93ca"}]}]}}