PubMed:16364460
Annnotations
LitCoin-entities-OrganismTaxon-PD
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 52-63 | OrganismTaxon | denotes | hippocampus | NCBItxid:72046 |
| T2 | 115-119 | OrganismTaxon | denotes | rats | NCBItxid:10118|NCBItxid:10116|NCBItxid:10114 |
| T5 | 277-281 | OrganismTaxon | denotes | Rats | NCBItxid:10118|NCBItxid:10116|NCBItxid:10114 |
| T8 | 363-374 | OrganismTaxon | denotes | hippocampus | NCBItxid:72046 |
| T9 | 1203-1207 | OrganismTaxon | denotes | rats | NCBItxid:10118|NCBItxid:10116|NCBItxid:10114 |
| T12 | 1499-1503 | OrganismTaxon | denotes | rats | NCBItxid:10118|NCBItxid:10116|NCBItxid:10114 |
| T15 | 1584-1595 | OrganismTaxon | denotes | hippocampus | NCBItxid:72046 |
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-120 | Sentence | denotes | Microinjection of ritanserin into the CA1 region of hippocampus improves scopolamine-induced amnesia in adult male rats. |
| T2 | 121-276 | Sentence | denotes | The effect of ritanserin (5-HT2 antagonist) on scopolamine (muscarinic cholinergic antagonist)-induced amnesia in Morris water maze (MWM) was investigated. |
| T3 | 277-375 | Sentence | denotes | Rats were divided into eight groups and bilaterally cannulated into CA1 region of the hippocampus. |
| T4 | 376-740 | Sentence | denotes | One week later, they received repeatedly vehicles (saline, DMSO, saline+DMSO), scopolamine (2 microg/0.5 microl saline/side; 30 min before training), ritanserin (2, 4 and 8 microg/0.5 microl DMSO/side; 20 min before training) and scopolamine (2 microg/0.5 microl; 30 min before ritanserin injection)+ritanserin (4 microg/0.5 microl DMSO) through cannulae each day. |
| T5 | 741-867 | Sentence | denotes | Animals were tested for four consecutive days (4 trial/day) in MWM during which the position of hidden platform was unchanged. |
| T6 | 868-1023 | Sentence | denotes | In the fifth day, the platform was elevated above the water surface in another position to evaluate the function of motor, motivational and visual systems. |
| T7 | 1024-1183 | Sentence | denotes | The results showed a significant increase in escape latencies and traveled distances to find platform in scopolamine-treated group as compared to saline group. |
| T8 | 1184-1327 | Sentence | denotes | Ritanserin-treated rats (4 microg/0.5 microl/side) showed a significant decrease in the mentioned parameters as compared to DMSO-treated group. |
| T9 | 1328-1504 | Sentence | denotes | However, scopolamine and ritanserin co-administration resulted in a significant decrease in escape latencies and traveled distances as compared to the scopolamine-treated rats. |
| T10 | 1505-1637 | Sentence | denotes | Our findings show that microinjection of ritanserin into the CA1 region of the hippocampus improves the scopolamine-induced amnesia. |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 2604 | 18-28 | ChemicalEntity | denotes | ritanserin | MESH:D016713 |
| 2605 | 73-84 | ChemicalEntity | denotes | scopolamine | MESH:D012601 |
| 2606 | 93-100 | DiseaseOrPhenotypicFeature | denotes | amnesia | MESH:D000647 |
| 2607 | 115-119 | OrganismTaxon | denotes | rats | NCBITaxon:10116 |
| 2608 | 135-145 | ChemicalEntity | denotes | ritanserin | MESH:D016713 |
| 2609 | 147-152 | GeneOrGeneProduct | denotes | 5-HT2 | NCBIGene:29595 |
| 2610 | 168-179 | ChemicalEntity | denotes | scopolamine | MESH:D012601 |
| 2611 | 181-203 | GeneOrGeneProduct | denotes | muscarinic cholinergic | NCBIGene:25229 |
| 2612 | 224-231 | DiseaseOrPhenotypicFeature | denotes | amnesia | MESH:D000647 |
| 2613 | 277-281 | OrganismTaxon | denotes | Rats | NCBITaxon:10116 |
| 2614 | 435-439 | ChemicalEntity | denotes | DMSO | MESH:D004121 |
| 2615 | 448-452 | ChemicalEntity | denotes | DMSO | MESH:D004121 |
| 2616 | 455-466 | ChemicalEntity | denotes | scopolamine | MESH:D012601 |
| 2617 | 526-536 | ChemicalEntity | denotes | ritanserin | MESH:D016713 |
| 2618 | 567-571 | ChemicalEntity | denotes | DMSO | MESH:D004121 |
| 2619 | 606-617 | ChemicalEntity | denotes | scopolamine | MESH:D012601 |
| 2620 | 654-664 | ChemicalEntity | denotes | ritanserin | MESH:D016713 |
| 2621 | 676-686 | ChemicalEntity | denotes | ritanserin | MESH:D016713 |
| 2622 | 708-712 | ChemicalEntity | denotes | DMSO | MESH:D004121 |
| 2623 | 1129-1140 | ChemicalEntity | denotes | scopolamine | MESH:D012601 |
| 2624 | 1184-1194 | ChemicalEntity | denotes | Ritanserin | MESH:D016713 |
| 2625 | 1203-1207 | OrganismTaxon | denotes | rats | NCBITaxon:10116 |
| 2626 | 1308-1312 | ChemicalEntity | denotes | DMSO | MESH:D004121 |
| 2627 | 1337-1348 | ChemicalEntity | denotes | scopolamine | MESH:D012601 |
| 2628 | 1353-1363 | ChemicalEntity | denotes | ritanserin | MESH:D016713 |
| 2629 | 1479-1490 | ChemicalEntity | denotes | scopolamine | MESH:D012601 |
| 2630 | 1499-1503 | OrganismTaxon | denotes | rats | NCBITaxon:10116 |
| 2631 | 1546-1556 | ChemicalEntity | denotes | ritanserin | MESH:D016713 |
| 2632 | 1609-1620 | ChemicalEntity | denotes | scopolamine | MESH:D012601 |
| 2633 | 1629-1636 | DiseaseOrPhenotypicFeature | denotes | amnesia | MESH:D000647 |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 147-152 | GeneOrGeneProduct | denotes | 5-HT2 |
| T2 | 495-499 | GeneOrGeneProduct | denotes | side |
| T3 | 572-576 | GeneOrGeneProduct | denotes | side |
| T4 | 928-935 | GeneOrGeneProduct | denotes | surface |
| T5 | 984-989 | GeneOrGeneProduct | denotes | motor |
| T6 | 1229-1233 | GeneOrGeneProduct | denotes | side |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 38-41 | GeneOrGeneProduct | denotes | CA1 |
| T2 | 85-92 | GeneOrGeneProduct | denotes | induced |
| T3 | 110-114 | GeneOrGeneProduct | denotes | male |
| T4 | 147-152 | GeneOrGeneProduct | denotes | 5-HT2 |
| T5 | 153-163 | GeneOrGeneProduct | denotes | antagonist |
| T6 | 204-214 | GeneOrGeneProduct | denotes | antagonist |
| T7 | 216-223 | GeneOrGeneProduct | denotes | induced |
| T8 | 248-252 | GeneOrGeneProduct | denotes | maze |
| T9 | 345-348 | GeneOrGeneProduct | denotes | CA1 |
| T10 | 385-390 | GeneOrGeneProduct | denotes | later |
| T11 | 495-499 | GeneOrGeneProduct | denotes | side |
| T12 | 541-546 | GeneOrGeneProduct | denotes | 4 and |
| T13 | 572-576 | GeneOrGeneProduct | denotes | side |
| T14 | 754-760 | GeneOrGeneProduct | denotes | tested |
| T15 | 928-935 | GeneOrGeneProduct | denotes | surface |
| T16 | 984-989 | GeneOrGeneProduct | denotes | motor |
| T17 | 1112-1116 | GeneOrGeneProduct | denotes | find |
| T18 | 1229-1233 | GeneOrGeneProduct | denotes | side |
| T19 | 1391-1395 | GeneOrGeneProduct | denotes | in a |
| T20 | 1509-1517 | GeneOrGeneProduct | denotes | findings |
| T21 | 1566-1569 | GeneOrGeneProduct | denotes | CA1 |
| T22 | 1621-1628 | GeneOrGeneProduct | denotes | induced |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 93-100 | DiseaseOrPhenotypicFeature | denotes | amnesia | D000647 |
| T2 | 224-231 | DiseaseOrPhenotypicFeature | denotes | amnesia | D000647 |
| T3 | 1629-1636 | DiseaseOrPhenotypicFeature | denotes | amnesia | D000647 |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 147-152 | GeneOrGeneProduct | denotes | 5-HT2 |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 93-100 | DiseaseOrPhenotypicFeature | denotes | amnesia | 0001152 |
| T2 | 224-231 | DiseaseOrPhenotypicFeature | denotes | amnesia | 0001152 |
| T3 | 1629-1636 | DiseaseOrPhenotypicFeature | denotes | amnesia | 0001152 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 93-100 | DiseaseOrPhenotypicFeature | denotes | amnesia | D000647 |
| T2 | 224-231 | DiseaseOrPhenotypicFeature | denotes | amnesia | D000647 |
| T3 | 1629-1636 | DiseaseOrPhenotypicFeature | denotes | amnesia | D000647 |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 93-100 | DiseaseOrPhenotypicFeature | denotes | amnesia | D000647 |
| T2 | 224-231 | DiseaseOrPhenotypicFeature | denotes | amnesia | D000647 |
| T3 | 1629-1636 | DiseaseOrPhenotypicFeature | denotes | amnesia | D000647 |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 18-28 | ChemicalEntity | denotes | ritanserin | D016713|http://purl.obolibrary.org/obo/CHEBI_64195 |
| T3 | 73-84 | ChemicalEntity | denotes | scopolamine | D012601|http://purl.obolibrary.org/obo/CHEBI_16794 |
| T5 | 135-145 | ChemicalEntity | denotes | ritanserin | D016713|http://purl.obolibrary.org/obo/CHEBI_64195 |
| T7 | 168-179 | ChemicalEntity | denotes | scopolamine | D012601|http://purl.obolibrary.org/obo/CHEBI_16794 |
| T9 | 242-247 | ChemicalEntity | denotes | water | D014867|http://purl.obolibrary.org/obo/CHEBI_15377 |
| T11 | 435-439 | ChemicalEntity | denotes | DMSO | D004121|http://purl.obolibrary.org/obo/CHEBI_28262 |
| T13 | 448-452 | ChemicalEntity | denotes | DMSO | D004121|http://purl.obolibrary.org/obo/CHEBI_28262 |
| T15 | 455-466 | ChemicalEntity | denotes | scopolamine | D012601|http://purl.obolibrary.org/obo/CHEBI_16794 |
| T17 | 526-536 | ChemicalEntity | denotes | ritanserin | D016713|http://purl.obolibrary.org/obo/CHEBI_64195 |
| T19 | 567-571 | ChemicalEntity | denotes | DMSO | D004121|http://purl.obolibrary.org/obo/CHEBI_28262 |
| T21 | 606-617 | ChemicalEntity | denotes | scopolamine | D012601|http://purl.obolibrary.org/obo/CHEBI_16794 |
| T23 | 654-664 | ChemicalEntity | denotes | ritanserin | D016713|http://purl.obolibrary.org/obo/CHEBI_64195 |
| T25 | 676-686 | ChemicalEntity | denotes | ritanserin | D016713|http://purl.obolibrary.org/obo/CHEBI_64195 |
| T27 | 708-712 | ChemicalEntity | denotes | DMSO | D004121|http://purl.obolibrary.org/obo/CHEBI_28262 |
| T29 | 922-927 | ChemicalEntity | denotes | water | D014867|http://purl.obolibrary.org/obo/CHEBI_15377 |
| T31 | 1129-1140 | ChemicalEntity | denotes | scopolamine | D012601|http://purl.obolibrary.org/obo/CHEBI_16794 |
| T33 | 1184-1194 | ChemicalEntity | denotes | Ritanserin | D016713|http://purl.obolibrary.org/obo/CHEBI_64195 |
| T35 | 1308-1312 | ChemicalEntity | denotes | DMSO | D004121|http://purl.obolibrary.org/obo/CHEBI_28262 |
| T37 | 1337-1348 | ChemicalEntity | denotes | scopolamine | D012601|http://purl.obolibrary.org/obo/CHEBI_16794 |
| T39 | 1353-1363 | ChemicalEntity | denotes | ritanserin | D016713|http://purl.obolibrary.org/obo/CHEBI_64195 |
| T41 | 1479-1490 | ChemicalEntity | denotes | scopolamine | D012601|http://purl.obolibrary.org/obo/CHEBI_16794 |
| T43 | 1546-1556 | ChemicalEntity | denotes | ritanserin | D016713|http://purl.obolibrary.org/obo/CHEBI_64195 |
| T45 | 1609-1620 | ChemicalEntity | denotes | scopolamine | D012601|http://purl.obolibrary.org/obo/CHEBI_16794 |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 115-119 | OrganismTaxon | denotes | rats |
| T2 | 277-281 | OrganismTaxon | denotes | Rats |
| T3 | 1203-1207 | OrganismTaxon | denotes | rats |
| T4 | 1499-1503 | OrganismTaxon | denotes | rats |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
|---|---|---|---|---|---|---|
| T45 | 1609-1620 | ChemicalEntity | denotes | scopolamine | http://purl.obolibrary.org/obo/CHEBI_16794|D012601 | |
| T43 | 1546-1556 | ChemicalEntity | denotes | ritanserin | http://purl.obolibrary.org/obo/CHEBI_64195|D016713 | |
| T41 | 1479-1490 | ChemicalEntity | denotes | scopolamine | http://purl.obolibrary.org/obo/CHEBI_16794|D012601 | |
| T39 | 1353-1363 | ChemicalEntity | denotes | ritanserin | http://purl.obolibrary.org/obo/CHEBI_64195|D016713 | |
| T37 | 1337-1348 | ChemicalEntity | denotes | scopolamine | http://purl.obolibrary.org/obo/CHEBI_16794|D012601 | |
| T35 | 1308-1312 | ChemicalEntity | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262|D004121 | |
| T33 | 1184-1194 | ChemicalEntity | denotes | Ritanserin | http://purl.obolibrary.org/obo/CHEBI_64195|D016713 | |
| T31 | 1129-1140 | ChemicalEntity | denotes | scopolamine | http://purl.obolibrary.org/obo/CHEBI_16794|D012601 | |
| T29 | 922-927 | ChemicalEntity | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377|D014867 | |
| T27 | 708-712 | ChemicalEntity | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262|D004121 | |
| T25 | 676-686 | ChemicalEntity | denotes | ritanserin | http://purl.obolibrary.org/obo/CHEBI_64195|D016713 | |
| T23 | 654-664 | ChemicalEntity | denotes | ritanserin | http://purl.obolibrary.org/obo/CHEBI_64195|D016713 | |
| T21 | 606-617 | ChemicalEntity | denotes | scopolamine | http://purl.obolibrary.org/obo/CHEBI_16794|D012601 | |
| T19 | 567-571 | ChemicalEntity | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262|D004121 | |
| T17 | 526-536 | ChemicalEntity | denotes | ritanserin | http://purl.obolibrary.org/obo/CHEBI_64195|D016713 | |
| T15 | 455-466 | ChemicalEntity | denotes | scopolamine | http://purl.obolibrary.org/obo/CHEBI_16794|D012601 | |
| T13 | 448-452 | ChemicalEntity | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262|D004121 | |
| T11 | 435-439 | ChemicalEntity | denotes | DMSO | http://purl.obolibrary.org/obo/CHEBI_28262|D004121 | |
| T9 | 242-247 | ChemicalEntity | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377|D014867 | |
| T7 | 168-179 | ChemicalEntity | denotes | scopolamine | http://purl.obolibrary.org/obo/CHEBI_16794|D012601 | |
| T5 | 135-145 | ChemicalEntity | denotes | ritanserin | http://purl.obolibrary.org/obo/CHEBI_64195|D016713 | |
| T3 | 73-84 | ChemicalEntity | denotes | scopolamine | http://purl.obolibrary.org/obo/CHEBI_16794|D012601 | |
| T1 | 18-28 | ChemicalEntity | denotes | ritanserin | http://purl.obolibrary.org/obo/CHEBI_64195|D016713 | |
| T843 | 147-152 | GeneOrGeneProduct | denotes | 5-HT2 | ||
| T90807 | 1629-1636 | DiseaseOrPhenotypicFeature | denotes | amnesia | D000647 | |
| T2 | 224-231 | DiseaseOrPhenotypicFeature | denotes | amnesia | D000647 | |
| T60369 | 93-100 | DiseaseOrPhenotypicFeature | denotes | amnesia | D000647 | |
| T4 | 1499-1503 | OrganismTaxon | denotes | rats | ||
| T88593 | 1203-1207 | OrganismTaxon | denotes | rats | ||
| T60347 | 277-281 | OrganismTaxon | denotes | Rats | ||
| T24525 | 115-119 | OrganismTaxon | denotes | rats |