PubMed:16252083 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/16252083","sourcedb":"PubMed","sourceid":"16252083","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/16252083","text":"Polymorphisms of the DNA mismatch repair gene HMSH2 in breast cancer occurence and progression.\nThe response of the cell to DNA damage and its ability to maintain genomic stability by DNA repair are crucial in preventing cancer initiation and progression. Therefore, polymorphism of DNA repair genes may affect the process of carcinogenesis. The importance of genetic variability of the components of mismatch repair (MMR) genes is well documented in colorectal cancer, but little is known about its role in breast cancer. hMSH2 is one of the crucial proteins of MMR. We performed a case-control study to test the association between two polymorphisms in the hMSH2 gene: an A --\u003e G transition at 127 position producing an Asn --\u003e Ser substitution at codon 127 (the Asn127Ser polymorphism) and a G --\u003e A transition at 1032 position resulting in a Gly --\u003e Asp change at codon 322 (the Gly322Asp polymorphism) and breast cancer risk and cancer progression. Genotypes were determined in DNA from peripheral blood lymphocytes of 150 breast cancer patients and 150 age-matched women (controls) by restriction fragment length polymorphism and allele-specific PCR. We did not observe any correlation between studied polymorphisms and breast cancer progression evaluated by node-metastasis, tumor size and Bloom-Richardson grading. A strong association between breast cancer occurrence and the Gly/Gly phenotype of the Gly322Asp polymorphism (odds ratio 8.39; 95% confidence interval 1.44-48.8) was found. Therefore, MMR may play a role in the breast carcinogenesis and the Gly322Asp polymorphism of the hMSH2 gene may be considered as a potential marker in breast cancer.","tracks":[{"project":"PubTator4TogoVar","denotations":[{"id":"16252083_0","span":{"begin":722,"end":759},"obj":"ProteinMutation"},{"id":"16252083_1","span":{"begin":846,"end":877},"obj":"ProteinMutation"},{"id":"16252083_2","span":{"begin":1385,"end":1392},"obj":"ProteinMutation"}],"attributes":[{"id":"16252083_0_ProteinMutation","pred":"proteinmutation","subj":"16252083_0","obj":"rs17217772"},{"id":"16252083_1_ProteinMutation","pred":"proteinmutation","subj":"16252083_1","obj":"rs4987188"},{"id":"16252083_2_ProteinMutation","pred":"proteinmutation","subj":"16252083_2","obj":"rs4987188"},{"subj":"16252083_0","pred":"source","obj":"PubTator4TogoVar"},{"subj":"16252083_1","pred":"source","obj":"PubTator4TogoVar"},{"subj":"16252083_2","pred":"source","obj":"PubTator4TogoVar"}]},{"project":"LitCoin-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":95},"obj":"Sentence"},{"id":"T2","span":{"begin":96,"end":255},"obj":"Sentence"},{"id":"T3","span":{"begin":256,"end":341},"obj":"Sentence"},{"id":"T4","span":{"begin":342,"end":567},"obj":"Sentence"},{"id":"T5","span":{"begin":568,"end":953},"obj":"Sentence"},{"id":"T6","span":{"begin":954,"end":1156},"obj":"Sentence"},{"id":"T7","span":{"begin":1157,"end":1322},"obj":"Sentence"},{"id":"T8","span":{"begin":1323,"end":1496},"obj":"Sentence"},{"id":"T9","span":{"begin":1497,"end":1663},"obj":"Sentence"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-sentences"},{"subj":"T2","pred":"source","obj":"LitCoin-sentences"},{"subj":"T3","pred":"source","obj":"LitCoin-sentences"},{"subj":"T4","pred":"source","obj":"LitCoin-sentences"},{"subj":"T5","pred":"source","obj":"LitCoin-sentences"},{"subj":"T6","pred":"source","obj":"LitCoin-sentences"},{"subj":"T7","pred":"source","obj":"LitCoin-sentences"},{"subj":"T8","pred":"source","obj":"LitCoin-sentences"},{"subj":"T9","pred":"source","obj":"LitCoin-sentences"}]},{"project":"LitCoin-entities-OrganismTaxon-PD","denotations":[{"id":"T1","span":{"begin":750,"end":755},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":868,"end":873},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"NCBItxid:79338"},{"id":"A2","pred":"db_id","subj":"T2","obj":"NCBItxid:79338"},{"subj":"T1","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"},{"subj":"T2","pred":"source","obj":"LitCoin-entities-OrganismTaxon-PD"}]},{"project":"LitCoin-entities","denotations":[{"id":"2434","span":{"begin":25,"end":40},"obj":"GeneOrGeneProduct"},{"id":"2435","span":{"begin":46,"end":51},"obj":"GeneOrGeneProduct"},{"id":"2436","span":{"begin":55,"end":68},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2437","span":{"begin":221,"end":238},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2438","span":{"begin":326,"end":340},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2439","span":{"begin":401,"end":416},"obj":"GeneOrGeneProduct"},{"id":"2440","span":{"begin":418,"end":421},"obj":"GeneOrGeneProduct"},{"id":"2441","span":{"begin":451,"end":468},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2442","span":{"begin":508,"end":521},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2443","span":{"begin":523,"end":528},"obj":"GeneOrGeneProduct"},{"id":"2444","span":{"begin":563,"end":566},"obj":"GeneOrGeneProduct"},{"id":"2445","span":{"begin":659,"end":664},"obj":"GeneOrGeneProduct"},{"id":"2446","span":{"begin":674,"end":708},"obj":"SequenceVariant"},{"id":"2447","span":{"begin":722,"end":759},"obj":"SequenceVariant"},{"id":"2448","span":{"begin":765,"end":774},"obj":"SequenceVariant"},{"id":"2449","span":{"begin":795,"end":830},"obj":"SequenceVariant"},{"id":"2450","span":{"begin":846,"end":877},"obj":"SequenceVariant"},{"id":"2451","span":{"begin":883,"end":892},"obj":"SequenceVariant"},{"id":"2452","span":{"begin":911,"end":924},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2453","span":{"begin":934,"end":940},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2454","span":{"begin":1028,"end":1041},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2455","span":{"begin":1042,"end":1050},"obj":"OrganismTaxon"},{"id":"2456","span":{"begin":1071,"end":1076},"obj":"OrganismTaxon"},{"id":"2457","span":{"begin":1226,"end":1239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2458","span":{"begin":1282,"end":1287},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2459","span":{"begin":1352,"end":1365},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2460","span":{"begin":1410,"end":1419},"obj":"SequenceVariant"},{"id":"2461","span":{"begin":1508,"end":1511},"obj":"GeneOrGeneProduct"},{"id":"2462","span":{"begin":1535,"end":1556},"obj":"DiseaseOrPhenotypicFeature"},{"id":"2463","span":{"begin":1565,"end":1574},"obj":"SequenceVariant"},{"id":"2464","span":{"begin":1595,"end":1600},"obj":"GeneOrGeneProduct"},{"id":"2465","span":{"begin":1649,"end":1662},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"db_id","subj":"2434","obj":"NCBIGene:4436"},{"id":"A2","pred":"db_id","subj":"2435","obj":"NCBIGene:4436"},{"id":"A3","pred":"db_id","subj":"2436","obj":"MESH:D001943"},{"id":"A4","pred":"db_id","subj":"2437","obj":"MESH:D009369"},{"id":"A5","pred":"db_id","subj":"2438","obj":"MESH:D063646"},{"id":"A6","pred":"db_id","subj":"2439","obj":"NCBIGene:4436"},{"id":"A7","pred":"db_id","subj":"2440","obj":"NCBIGene:4436"},{"id":"A8","pred":"db_id","subj":"2441","obj":"MESH:D015179"},{"id":"A9","pred":"db_id","subj":"2442","obj":"MESH:D001943"},{"id":"A10","pred":"db_id","subj":"2443","obj":"NCBIGene:4436"},{"id":"A11","pred":"db_id","subj":"2444","obj":"NCBIGene:4436"},{"id":"A12","pred":"db_id","subj":"2445","obj":"NCBIGene:4436"},{"id":"A13","pred":"db_id","subj":"2446","obj":"DBSNP:rs17217772"},{"id":"A14","pred":"db_id","subj":"2447","obj":"DBSNP:rs17217772"},{"id":"A15","pred":"db_id","subj":"2448","obj":"DBSNP:rs17217772"},{"id":"A16","pred":"db_id","subj":"2449","obj":"DBSNP:rs4987188"},{"id":"A17","pred":"db_id","subj":"2450","obj":"DBSNP:rs4987188"},{"id":"A18","pred":"db_id","subj":"2451","obj":"DBSNP:rs4987188"},{"id":"A19","pred":"db_id","subj":"2452","obj":"MESH:D001943"},{"id":"A20","pred":"db_id","subj":"2453","obj":"MESH:D009369"},{"id":"A21","pred":"db_id","subj":"2454","obj":"MESH:D001943"},{"id":"A22","pred":"db_id","subj":"2455","obj":"NCBITaxon:9606"},{"id":"A23","pred":"db_id","subj":"2456","obj":"NCBITaxon:9606"},{"id":"A24","pred":"db_id","subj":"2457","obj":"MESH:D001943"},{"id":"A25","pred":"db_id","subj":"2458","obj":"MESH:D009369"},{"id":"A26","pred":"db_id","subj":"2459","obj":"MESH:D001943"},{"id":"A27","pred":"db_id","subj":"2460","obj":"DBSNP:rs4987188"},{"id":"A28","pred":"db_id","subj":"2461","obj":"NCBIGene:4436"},{"id":"A29","pred":"db_id","subj":"2462","obj":"MESH:D001943"},{"id":"A30","pred":"db_id","subj":"2463","obj":"DBSNP:rs4987188"},{"id":"A31","pred":"db_id","subj":"2464","obj":"NCBIGene:4436"},{"id":"A32","pred":"db_id","subj":"2465","obj":"MESH:D001943"},{"subj":"2434","pred":"source","obj":"LitCoin-entities"},{"subj":"2435","pred":"source","obj":"LitCoin-entities"},{"subj":"2436","pred":"source","obj":"LitCoin-entities"},{"subj":"2437","pred":"source","obj":"LitCoin-entities"},{"subj":"2438","pred":"source","obj":"LitCoin-entities"},{"subj":"2439","pred":"source","obj":"LitCoin-entities"},{"subj":"2440","pred":"source","obj":"LitCoin-entities"},{"subj":"2441","pred":"source","obj":"LitCoin-entities"},{"subj":"2442","pred":"source","obj":"LitCoin-entities"},{"subj":"2443","pred":"source","obj":"LitCoin-entities"},{"subj":"2444","pred":"source","obj":"LitCoin-entities"},{"subj":"2445","pred":"source","obj":"LitCoin-entities"},{"subj":"2446","pred":"source","obj":"LitCoin-entities"},{"subj":"2447","pred":"source","obj":"LitCoin-entities"},{"subj":"2448","pred":"source","obj":"LitCoin-entities"},{"subj":"2449","pred":"source","obj":"LitCoin-entities"},{"subj":"2450","pred":"source","obj":"LitCoin-entities"},{"subj":"2451","pred":"source","obj":"LitCoin-entities"},{"subj":"2452","pred":"source","obj":"LitCoin-entities"},{"subj":"2453","pred":"source","obj":"LitCoin-entities"},{"subj":"2454","pred":"source","obj":"LitCoin-entities"},{"subj":"2455","pred":"source","obj":"LitCoin-entities"},{"subj":"2456","pred":"source","obj":"LitCoin-entities"},{"subj":"2457","pred":"source","obj":"LitCoin-entities"},{"subj":"2458","pred":"source","obj":"LitCoin-entities"},{"subj":"2459","pred":"source","obj":"LitCoin-entities"},{"subj":"2460","pred":"source","obj":"LitCoin-entities"},{"subj":"2461","pred":"source","obj":"LitCoin-entities"},{"subj":"2462","pred":"source","obj":"LitCoin-entities"},{"subj":"2463","pred":"source","obj":"LitCoin-entities"},{"subj":"2464","pred":"source","obj":"LitCoin-entities"},{"subj":"2465","pred":"source","obj":"LitCoin-entities"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}]},{"project":"LitCoin_Mondo","denotations":[{"id":"T1","span":{"begin":55,"end":68},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":62,"end":68},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":221,"end":227},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":451,"end":468},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":462,"end":468},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":508,"end":521},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":515,"end":521},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":911,"end":924},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":918,"end":924},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":934,"end":940},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":1028,"end":1041},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":1035,"end":1041},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T13","span":{"begin":1226,"end":1239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T14","span":{"begin":1233,"end":1239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T15","span":{"begin":1352,"end":1365},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T16","span":{"begin":1359,"end":1365},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T17","span":{"begin":1649,"end":1662},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T18","span":{"begin":1656,"end":1662},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A18","pred":"mondo_id","subj":"T18","obj":"0004992"},{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0007254"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0005575"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"0007254"},{"id":"A15","pred":"mondo_id","subj":"T15","obj":"0007254"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"0004992"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"0004992"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"0004992"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"0004992"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"0004992"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0004992"},{"id":"A17","pred":"mondo_id","subj":"T17","obj":"0007254"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"0007254"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"0007254"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"0007254"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"0004992"},{"id":"A16","pred":"mondo_id","subj":"T16","obj":"0004992"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"0004992"},{"subj":"T1","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T2","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T3","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T4","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T5","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T6","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T7","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T8","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T9","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T10","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T11","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T12","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T13","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T14","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T15","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T16","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T17","pred":"source","obj":"LitCoin_Mondo"},{"subj":"T18","pred":"source","obj":"LitCoin_Mondo"}]},{"project":"LitCoin-SeqVar","denotations":[{"id":"T1","span":{"begin":765,"end":774},"obj":"SequenceVariant"},{"id":"T2","span":{"begin":883,"end":892},"obj":"SequenceVariant"},{"id":"T3","span":{"begin":1410,"end":1419},"obj":"SequenceVariant"},{"id":"T4","span":{"begin":1565,"end":1574},"obj":"SequenceVariant"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-SeqVar"},{"subj":"T2","pred":"source","obj":"LitCoin-SeqVar"},{"subj":"T3","pred":"source","obj":"LitCoin-SeqVar"},{"subj":"T4","pred":"source","obj":"LitCoin-SeqVar"}]},{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T1","span":{"begin":21,"end":40},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":46,"end":51},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":116,"end":120},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":128,"end":134},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":184,"end":194},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":228,"end":238},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":283,"end":293},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":315,"end":322},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":474,"end":480},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":523,"end":528},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":551,"end":559},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":583,"end":587},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":605,"end":609},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":659,"end":664},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":671,"end":681},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":722,"end":725},"obj":"GeneOrGeneProduct"},{"id":"T17","span":{"begin":730,"end":733},"obj":"GeneOrGeneProduct"},{"id":"T18","span":{"begin":841,"end":845},"obj":"GeneOrGeneProduct"},{"id":"T19","span":{"begin":969,"end":979},"obj":"GeneOrGeneProduct"},{"id":"T20","span":{"begin":1009,"end":1020},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":1265,"end":1269},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":1282,"end":1287},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":1288,"end":1292},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":1297,"end":1302},"obj":"GeneOrGeneProduct"},{"id":"T25","span":{"begin":1595,"end":1600},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T12","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T13","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T14","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T15","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T16","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T17","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T18","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T19","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T20","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T21","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T22","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T23","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T24","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"},{"subj":"T25","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v0"}]},{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T1","span":{"begin":21,"end":40},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":46,"end":51},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":116,"end":120},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":184,"end":194},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":283,"end":293},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":474,"end":480},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":523,"end":528},"obj":"GeneOrGeneProduct"},{"id":"T8","span":{"begin":659,"end":664},"obj":"GeneOrGeneProduct"},{"id":"T9","span":{"begin":1009,"end":1020},"obj":"GeneOrGeneProduct"},{"id":"T10","span":{"begin":1297,"end":1302},"obj":"GeneOrGeneProduct"},{"id":"T11","span":{"begin":1595,"end":1600},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T7","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T8","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T9","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T10","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"},{"subj":"T11","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v2"}]},{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T1","span":{"begin":55,"end":68},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":163,"end":180},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":221,"end":227},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":326,"end":340},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":451,"end":468},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":508,"end":521},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":911,"end":924},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":934,"end":940},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":1028,"end":1041},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":1226,"end":1239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":1270,"end":1280},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":1282,"end":1287},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T13","span":{"begin":1352,"end":1365},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T14","span":{"begin":1542,"end":1556},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T15","span":{"begin":1649,"end":1662},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A7","pred":"originalLabel","subj":"T7","obj":"D001943"},{"id":"A9","pred":"originalLabel","subj":"T9","obj":"D001943"},{"id":"A1","pred":"originalLabel","subj":"T1","obj":"D001943"},{"id":"A14","pred":"originalLabel","subj":"T14","obj":"D063646"},{"id":"A6","pred":"originalLabel","subj":"T6","obj":"D001943"},{"id":"A11","pred":"originalLabel","subj":"T11","obj":"D009362"},{"id":"A3","pred":"originalLabel","subj":"T3","obj":"D009369"},{"id":"A8","pred":"originalLabel","subj":"T8","obj":"D009369"},{"id":"A12","pred":"originalLabel","subj":"T12","obj":"D009369"},{"id":"A15","pred":"originalLabel","subj":"T15","obj":"D001943"},{"id":"A5","pred":"originalLabel","subj":"T5","obj":"D015179"},{"id":"A10","pred":"originalLabel","subj":"T10","obj":"D001943"},{"id":"A4","pred":"originalLabel","subj":"T4","obj":"D063646"},{"id":"A13","pred":"originalLabel","subj":"T13","obj":"D001943"},{"id":"A2","pred":"originalLabel","subj":"T2","obj":"D042822"},{"subj":"T1","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T2","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T3","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T4","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T5","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T6","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T7","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T8","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T9","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T10","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T11","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T12","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T13","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T14","pred":"source","obj":"LitCoin-Disease-MeSH"},{"subj":"T15","pred":"source","obj":"LitCoin-Disease-MeSH"}]},{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T1","span":{"begin":21,"end":40},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":46,"end":51},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":523,"end":528},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":659,"end":664},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":1297,"end":1302},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":1595,"end":1600},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T2","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T3","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T4","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T5","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"},{"subj":"T6","pred":"source","obj":"LitCoin-GeneOrGeneProduct-v3"}]},{"project":"LitCoin_Mondo_095","denotations":[{"id":"T1","span":{"begin":55,"end":68},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":451,"end":468},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":508,"end":521},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":911,"end":924},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":1028,"end":1041},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":1226,"end":1239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T13","span":{"begin":1282,"end":1287},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T14","span":{"begin":1352,"end":1365},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T16","span":{"begin":1649,"end":1662},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A13","pred":"mondo_id","subj":"T13","obj":"0005070"},{"id":"A16","pred":"mondo_id","subj":"T16","obj":"0007254"},{"id":"A17","pred":"mondo_id","subj":"T16","obj":"0004989"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"0007254"},{"id":"A10","pred":"mondo_id","subj":"T9","obj":"0004989"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"0024331"},{"id":"A4","pred":"mondo_id","subj":"T3","obj":"0005575"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"0007254"},{"id":"A15","pred":"mondo_id","subj":"T14","obj":"0004989"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"0007254"},{"id":"A12","pred":"mondo_id","subj":"T11","obj":"0004989"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"0007254"},{"id":"A8","pred":"mondo_id","subj":"T7","obj":"0004989"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"0007254"},{"id":"A6","pred":"mondo_id","subj":"T5","obj":"0004989"},{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0007254"},{"id":"A2","pred":"mondo_id","subj":"T1","obj":"0004989"},{"subj":"T1","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T3","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T5","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T7","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T9","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T11","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T13","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T14","pred":"source","obj":"LitCoin_Mondo_095"},{"subj":"T16","pred":"source","obj":"LitCoin_Mondo_095"}]},{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T1","span":{"begin":55,"end":68},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":163,"end":180},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":221,"end":227},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":326,"end":340},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":451,"end":468},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":508,"end":521},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":911,"end":924},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":934,"end":940},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":1028,"end":1041},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":1226,"end":1239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":1270,"end":1280},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":1282,"end":1287},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T13","span":{"begin":1352,"end":1365},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T14","span":{"begin":1542,"end":1556},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T15","span":{"begin":1649,"end":1662},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"ID:","subj":"T1","obj":"D001943"},{"id":"A10","pred":"ID:","subj":"T10","obj":"D001943"},{"id":"A9","pred":"ID:","subj":"T9","obj":"D001943"},{"id":"A5","pred":"ID:","subj":"T5","obj":"D015179"},{"id":"A11","pred":"ID:","subj":"T11","obj":"D009362"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D009369"},{"id":"A7","pred":"ID:","subj":"T7","obj":"D001943"},{"id":"A15","pred":"ID:","subj":"T15","obj":"D001943"},{"id":"A2","pred":"ID:","subj":"T2","obj":"D042822"},{"id":"A8","pred":"ID:","subj":"T8","obj":"D009369"},{"id":"A14","pred":"ID:","subj":"T14","obj":"D063646"},{"id":"A6","pred":"ID:","subj":"T6","obj":"D001943"},{"id":"A4","pred":"ID:","subj":"T4","obj":"D063646"},{"id":"A13","pred":"ID:","subj":"T13","obj":"D001943"},{"id":"A12","pred":"ID:","subj":"T12","obj":"D009369"},{"subj":"T1","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T2","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T3","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T4","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T5","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T6","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T7","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T8","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T9","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T10","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T11","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T12","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T13","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T14","pred":"source","obj":"LitCoin-MeSH-Disease-2"},{"subj":"T15","pred":"source","obj":"LitCoin-MeSH-Disease-2"}]},{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T1","span":{"begin":55,"end":68},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":163,"end":180},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":221,"end":227},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":326,"end":340},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":451,"end":468},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":508,"end":521},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":911,"end":924},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":934,"end":940},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":1028,"end":1041},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T10","span":{"begin":1226,"end":1239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T11","span":{"begin":1282,"end":1287},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":1352,"end":1365},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T13","span":{"begin":1542,"end":1556},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T14","span":{"begin":1649,"end":1662},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A3","pred":"#label","subj":"T3","obj":"D009369"},{"id":"A9","pred":"#label","subj":"T9","obj":"D001943"},{"id":"A12","pred":"#label","subj":"T12","obj":"D001943"},{"id":"A14","pred":"#label","subj":"T14","obj":"D001943"},{"id":"A10","pred":"#label","subj":"T10","obj":"D001943"},{"id":"A2","pred":"#label","subj":"T2","obj":"D042822"},{"id":"A6","pred":"#label","subj":"T6","obj":"D001943"},{"id":"A7","pred":"#label","subj":"T7","obj":"D001943"},{"id":"A13","pred":"#label","subj":"T13","obj":"D063646"},{"id":"A4","pred":"#label","subj":"T4","obj":"D063646"},{"id":"A1","pred":"#label","subj":"T1","obj":"D001943"},{"id":"A8","pred":"#label","subj":"T8","obj":"D009369"},{"id":"A11","pred":"#label","subj":"T11","obj":"D009369"},{"id":"A5","pred":"#label","subj":"T5","obj":"D015179"},{"subj":"T1","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T2","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T3","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T4","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T5","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T6","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T7","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T8","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T9","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T10","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T11","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T12","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T13","pred":"source","obj":"LitCoin-MONDO_bioort2019"},{"subj":"T14","pred":"source","obj":"LitCoin-MONDO_bioort2019"}]},{"project":"LitCoin-NCBITaxon-2","denotations":[{"id":"T1","span":{"begin":1042,"end":1050},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":1071,"end":1076},"obj":"OrganismTaxon"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCoin-NCBITaxon-2"},{"subj":"T2","pred":"source","obj":"LitCoin-NCBITaxon-2"}]},{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T1","span":{"begin":722,"end":725},"obj":"ChemicalEntity"},{"id":"T4","span":{"begin":730,"end":733},"obj":"ChemicalEntity"},{"id":"T6","span":{"begin":846,"end":849},"obj":"ChemicalEntity"},{"id":"T7","span":{"begin":854,"end":857},"obj":"ChemicalEntity"},{"id":"T10","span":{"begin":1385,"end":1388},"obj":"ChemicalEntity"},{"id":"T11","span":{"begin":1389,"end":1392},"obj":"ChemicalEntity"}],"attributes":[{"id":"A1","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_50347"},{"id":"A2","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_22653"},{"id":"A3","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_17196"},{"id":"A4","pred":"ID:","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_29999"},{"id":"A5","pred":"ID:","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_17115"},{"id":"A6","pred":"ID:","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_15428"},{"id":"A7","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_29958"},{"id":"A8","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_22660"},{"id":"A9","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_17053"},{"id":"A10","pred":"ID:","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_15428"},{"id":"A11","pred":"ID:","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_15428"},{"subj":"T1","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T4","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T6","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T7","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T10","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"},{"subj":"T11","pred":"source","obj":"LitCoin-Chemical-MeSH-CHEBI"}]},{"project":"LitCoin-training-merged","denotations":[{"id":"T11","span":{"begin":1389,"end":1392},"obj":"ChemicalEntity"},{"id":"T10","span":{"begin":1385,"end":1388},"obj":"ChemicalEntity"},{"id":"T7","span":{"begin":854,"end":857},"obj":"ChemicalEntity"},{"id":"T6","span":{"begin":846,"end":849},"obj":"ChemicalEntity"},{"id":"T4","span":{"begin":730,"end":733},"obj":"ChemicalEntity"},{"id":"T1","span":{"begin":722,"end":725},"obj":"ChemicalEntity"},{"id":"T60117","span":{"begin":1595,"end":1600},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":1297,"end":1302},"obj":"GeneOrGeneProduct"},{"id":"T37804","span":{"begin":659,"end":664},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":523,"end":528},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":46,"end":51},"obj":"GeneOrGeneProduct"},{"id":"T15107","span":{"begin":21,"end":40},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":1649,"end":1662},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T13","span":{"begin":1542,"end":1556},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T12","span":{"begin":1352,"end":1365},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T70260","span":{"begin":1282,"end":1287},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T95228","span":{"begin":1226,"end":1239},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":1028,"end":1041},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":934,"end":940},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T26934","span":{"begin":911,"end":924},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T83118","span":{"begin":508,"end":521},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T64134","span":{"begin":451,"end":468},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3305","span":{"begin":326,"end":340},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T23407","span":{"begin":221,"end":227},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T54787","span":{"begin":163,"end":180},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T78331","span":{"begin":55,"end":68},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T66454","span":{"begin":1071,"end":1076},"obj":"OrganismTaxon"},{"id":"T82406","span":{"begin":1042,"end":1050},"obj":"OrganismTaxon"},{"id":"T79477","span":{"begin":1565,"end":1574},"obj":"SequenceVariant"},{"id":"T33166","span":{"begin":1410,"end":1419},"obj":"SequenceVariant"},{"id":"T5825","span":{"begin":883,"end":892},"obj":"SequenceVariant"},{"id":"T64918","span":{"begin":765,"end":774},"obj":"SequenceVariant"}],"attributes":[{"id":"A11","pred":"ID:","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_15428"},{"id":"A10","pred":"ID:","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_15428"},{"id":"A9","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_17053"},{"id":"A8","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_22660"},{"id":"A7","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_29958"},{"id":"A6","pred":"ID:","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_15428"},{"id":"A5","pred":"ID:","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_17115"},{"id":"A4","pred":"ID:","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_29999"},{"id":"A3","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_17196"},{"id":"A2","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_22653"},{"id":"A1","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_50347"},{"id":"A14","pred":"#label","subj":"T14","obj":"D001943"},{"id":"A13","pred":"#label","subj":"T13","obj":"D063646"},{"id":"A12","pred":"#label","subj":"T12","obj":"D001943"},{"id":"A35657","pred":"#label","subj":"T70260","obj":"D009369"},{"id":"A41651","pred":"#label","subj":"T95228","obj":"D001943"},{"id":"A94176","pred":"#label","subj":"T9","obj":"D001943"},{"id":"A1478","pred":"#label","subj":"T8","obj":"D009369"},{"id":"A38131","pred":"#label","subj":"T26934","obj":"D001943"},{"id":"A15535","pred":"#label","subj":"T83118","obj":"D001943"},{"id":"A14255","pred":"#label","subj":"T64134","obj":"D015179"},{"id":"A45946","pred":"#label","subj":"T3305","obj":"D063646"},{"id":"A80072","pred":"#label","subj":"T23407","obj":"D009369"},{"id":"A45746","pred":"#label","subj":"T54787","obj":"D042822"},{"id":"A35321","pred":"#label","subj":"T78331","obj":"D001943"},{"subj":"T11","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T10","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T7","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T6","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T4","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T1","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T60117","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T5","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T37804","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T3","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T2","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T15107","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T14","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T13","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T12","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T70260","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T95228","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T9","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T8","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T26934","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T83118","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T64134","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T3305","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T23407","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T54787","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T78331","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T66454","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T82406","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T79477","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T33166","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T5825","pred":"source","obj":"LitCoin-training-merged"},{"subj":"T64918","pred":"source","obj":"LitCoin-training-merged"}]},{"project":"DisGeNET5_variant_disease","denotations":[{"id":"16252083-4#315#324#geners4987188","span":{"begin":883,"end":892},"obj":"geners4987188"},{"id":"16252083-4#197#206#geners17217772","span":{"begin":765,"end":774},"obj":"geners17217772"},{"id":"16252083-4#366#384#diseaseC0178874","span":{"begin":934,"end":952},"obj":"diseaseC0178874"},{"id":"16252083-4#343#356#diseaseC0006142","span":{"begin":911,"end":924},"obj":"diseaseC0006142"},{"id":"16252083-4#343#356#diseaseC0678222","span":{"begin":911,"end":924},"obj":"diseaseC0678222"},{"id":"16252083-4#366#384#diseaseC0178874","span":{"begin":934,"end":952},"obj":"diseaseC0178874"},{"id":"16252083-8#68#77#geners4987188","span":{"begin":1565,"end":1574},"obj":"geners4987188"},{"id":"16252083-8#45#59#diseaseC0596263","span":{"begin":1542,"end":1556},"obj":"diseaseC0596263"},{"id":"16252083-8#152#165#diseaseC0006142","span":{"begin":1649,"end":1662},"obj":"diseaseC0006142"},{"id":"16252083-8#152#165#diseaseC0678222","span":{"begin":1649,"end":1662},"obj":"diseaseC0678222"}],"relations":[{"id":"315#324#geners4987188366#384#diseaseC0178874","pred":"associated_with","subj":"16252083-4#315#324#geners4987188","obj":"16252083-4#366#384#diseaseC0178874"},{"id":"315#324#geners4987188343#356#diseaseC0006142","pred":"associated_with","subj":"16252083-4#315#324#geners4987188","obj":"16252083-4#343#356#diseaseC0006142"},{"id":"315#324#geners4987188343#356#diseaseC0678222","pred":"associated_with","subj":"16252083-4#315#324#geners4987188","obj":"16252083-4#343#356#diseaseC0678222"},{"id":"315#324#geners4987188366#384#diseaseC0178874","pred":"associated_with","subj":"16252083-4#315#324#geners4987188","obj":"16252083-4#366#384#diseaseC0178874"},{"id":"197#206#geners17217772366#384#diseaseC0178874","pred":"associated_with","subj":"16252083-4#197#206#geners17217772","obj":"16252083-4#366#384#diseaseC0178874"},{"id":"197#206#geners17217772343#356#diseaseC0006142","pred":"associated_with","subj":"16252083-4#197#206#geners17217772","obj":"16252083-4#343#356#diseaseC0006142"},{"id":"197#206#geners17217772343#356#diseaseC0678222","pred":"associated_with","subj":"16252083-4#197#206#geners17217772","obj":"16252083-4#343#356#diseaseC0678222"},{"id":"197#206#geners17217772366#384#diseaseC0178874","pred":"associated_with","subj":"16252083-4#197#206#geners17217772","obj":"16252083-4#366#384#diseaseC0178874"},{"id":"68#77#geners498718845#59#diseaseC0596263","pred":"associated_with","subj":"16252083-8#68#77#geners4987188","obj":"16252083-8#45#59#diseaseC0596263"},{"id":"68#77#geners4987188152#165#diseaseC0006142","pred":"associated_with","subj":"16252083-8#68#77#geners4987188","obj":"16252083-8#152#165#diseaseC0006142"},{"id":"68#77#geners4987188152#165#diseaseC0678222","pred":"associated_with","subj":"16252083-8#68#77#geners4987188","obj":"16252083-8#152#165#diseaseC0678222"}],"attributes":[{"subj":"16252083-4#315#324#geners4987188","pred":"source","obj":"DisGeNET5_variant_disease"},{"subj":"16252083-4#197#206#geners17217772","pred":"source","obj":"DisGeNET5_variant_disease"},{"subj":"16252083-4#366#384#diseaseC0178874","pred":"source","obj":"DisGeNET5_variant_disease"},{"subj":"16252083-4#343#356#diseaseC0006142","pred":"source","obj":"DisGeNET5_variant_disease"},{"subj":"16252083-4#343#356#diseaseC0678222","pred":"source","obj":"DisGeNET5_variant_disease"},{"subj":"16252083-4#366#384#diseaseC0178874","pred":"source","obj":"DisGeNET5_variant_disease"},{"subj":"16252083-8#68#77#geners4987188","pred":"source","obj":"DisGeNET5_variant_disease"},{"subj":"16252083-8#45#59#diseaseC0596263","pred":"source","obj":"DisGeNET5_variant_disease"},{"subj":"16252083-8#152#165#diseaseC0006142","pred":"source","obj":"DisGeNET5_variant_disease"},{"subj":"16252083-8#152#165#diseaseC0678222","pred":"source","obj":"DisGeNET5_variant_disease"}]},{"project":"DisGeNET5_gene_disease","denotations":[{"id":"16252083-0#46#51#gene4436","span":{"begin":46,"end":51},"obj":"gene4436"},{"id":"16252083-0#55#68#diseaseC0006142","span":{"begin":55,"end":68},"obj":"diseaseC0006142"},{"id":"16252083-0#55#68#diseaseC0678222","span":{"begin":55,"end":68},"obj":"diseaseC0678222"},{"id":"16252083-3#76#79#gene4360","span":{"begin":418,"end":421},"obj":"gene4360"},{"id":"16252083-3#109#126#diseaseC0009402","span":{"begin":451,"end":468},"obj":"diseaseC0009402"},{"id":"16252083-3#109#126#diseaseC1527249","span":{"begin":451,"end":468},"obj":"diseaseC1527249"},{"id":"16252083-3#166#179#diseaseC0006142","span":{"begin":508,"end":521},"obj":"diseaseC0006142"},{"id":"16252083-3#166#179#diseaseC0678222","span":{"begin":508,"end":521},"obj":"diseaseC0678222"},{"id":"16252083-4#91#96#gene4436","span":{"begin":659,"end":664},"obj":"gene4436"},{"id":"16252083-4#366#384#diseaseC0178874","span":{"begin":934,"end":952},"obj":"diseaseC0178874"},{"id":"16252083-8#98#103#gene4436","span":{"begin":1595,"end":1600},"obj":"gene4436"},{"id":"16252083-8#45#59#diseaseC0596263","span":{"begin":1542,"end":1556},"obj":"diseaseC0596263"}],"relations":[{"id":"46#51#gene443655#68#diseaseC0006142","pred":"associated_with","subj":"16252083-0#46#51#gene4436","obj":"16252083-0#55#68#diseaseC0006142"},{"id":"46#51#gene443655#68#diseaseC0678222","pred":"associated_with","subj":"16252083-0#46#51#gene4436","obj":"16252083-0#55#68#diseaseC0678222"},{"id":"76#79#gene4360109#126#diseaseC0009402","pred":"associated_with","subj":"16252083-3#76#79#gene4360","obj":"16252083-3#109#126#diseaseC0009402"},{"id":"76#79#gene4360109#126#diseaseC1527249","pred":"associated_with","subj":"16252083-3#76#79#gene4360","obj":"16252083-3#109#126#diseaseC1527249"},{"id":"76#79#gene4360166#179#diseaseC0006142","pred":"associated_with","subj":"16252083-3#76#79#gene4360","obj":"16252083-3#166#179#diseaseC0006142"},{"id":"76#79#gene4360166#179#diseaseC0678222","pred":"associated_with","subj":"16252083-3#76#79#gene4360","obj":"16252083-3#166#179#diseaseC0678222"},{"id":"91#96#gene4436366#384#diseaseC0178874","pred":"associated_with","subj":"16252083-4#91#96#gene4436","obj":"16252083-4#366#384#diseaseC0178874"},{"id":"98#103#gene443645#59#diseaseC0596263","pred":"associated_with","subj":"16252083-8#98#103#gene4436","obj":"16252083-8#45#59#diseaseC0596263"}],"attributes":[{"subj":"16252083-0#46#51#gene4436","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"16252083-0#55#68#diseaseC0006142","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"16252083-0#55#68#diseaseC0678222","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"16252083-3#76#79#gene4360","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"16252083-3#109#126#diseaseC0009402","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"16252083-3#109#126#diseaseC1527249","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"16252083-3#166#179#diseaseC0006142","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"16252083-3#166#179#diseaseC0678222","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"16252083-4#91#96#gene4436","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"16252083-4#366#384#diseaseC0178874","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"16252083-8#98#103#gene4436","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"16252083-8#45#59#diseaseC0596263","pred":"source","obj":"DisGeNET5_gene_disease"}]},{"project":"tmVarCorpus","denotations":[{"id":"T1","span":{"begin":674,"end":708},"obj":"DNAMutation:|SUB|A|CODON127|G"},{"id":"T2","span":{"begin":722,"end":759},"obj":"ProteinMutation:p|SUB|N|127|S"},{"id":"T3","span":{"begin":765,"end":774},"obj":"ProteinMutation:p|SUB|N|127|S"},{"id":"T4","span":{"begin":795,"end":830},"obj":"DNAMutation:g|SUB|G|1032|A"},{"id":"T5","span":{"begin":846,"end":877},"obj":"ProteinMutation:p|SUB|G|322|D"},{"id":"T6","span":{"begin":883,"end":892},"obj":"ProteinMutation:p|SUB|G|322|D"},{"id":"T7","span":{"begin":1410,"end":1419},"obj":"ProteinMutation:p|SUB|G|322|D"},{"id":"T8","span":{"begin":1565,"end":1574},"obj":"ProteinMutation:p|SUB|G|322|D"}],"attributes":[{"subj":"T1","pred":"source","obj":"tmVarCorpus"},{"subj":"T2","pred":"source","obj":"tmVarCorpus"},{"subj":"T3","pred":"source","obj":"tmVarCorpus"},{"subj":"T4","pred":"source","obj":"tmVarCorpus"},{"subj":"T5","pred":"source","obj":"tmVarCorpus"},{"subj":"T6","pred":"source","obj":"tmVarCorpus"},{"subj":"T7","pred":"source","obj":"tmVarCorpus"},{"subj":"T8","pred":"source","obj":"tmVarCorpus"}]},{"project":"DisGeNET","denotations":[{"id":"T0","span":{"begin":1595,"end":1600},"obj":"gene:4436"},{"id":"T1","span":{"begin":1649,"end":1662},"obj":"disease:C0006142"},{"id":"T2","span":{"begin":1595,"end":1600},"obj":"gene:4436"},{"id":"T3","span":{"begin":1649,"end":1662},"obj":"disease:C0678222"}],"relations":[{"id":"R1","pred":"associated_with","subj":"T0","obj":"T1"},{"id":"R2","pred":"associated_with","subj":"T2","obj":"T3"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"attributes":[{"subj":"T0","pred":"source","obj":"DisGeNET"},{"subj":"T1","pred":"source","obj":"DisGeNET"},{"subj":"T2","pred":"source","obj":"DisGeNET"},{"subj":"T3","pred":"source","obj":"DisGeNET"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubTator4TogoVar","color":"#d093ec","default":true},{"id":"LitCoin-sentences","color":"#93ecb6"},{"id":"LitCoin-entities-OrganismTaxon-PD","color":"#ec9c93"},{"id":"LitCoin-entities","color":"#93a3ec"},{"id":"LitCoin_Mondo","color":"#beec93"},{"id":"LitCoin-SeqVar","color":"#ec93d8"},{"id":"LitCoin-GeneOrGeneProduct-v0","color":"#93ece6"},{"id":"LitCoin-GeneOrGeneProduct-v2","color":"#eccc93"},{"id":"LitCoin-Disease-MeSH","color":"#b293ec"},{"id":"LitCoin-GeneOrGeneProduct-v3","color":"#93ec98"},{"id":"LitCoin_Mondo_095","color":"#ec93a7"},{"id":"LitCoin-MeSH-Disease-2","color":"#93c1ec"},{"id":"LitCoin-MONDO_bioort2019","color":"#dbec93"},{"id":"LitCoin-NCBITaxon-2","color":"#e293ec"},{"id":"LitCoin-Chemical-MeSH-CHEBI","color":"#93ecc8"},{"id":"LitCoin-training-merged","color":"#ecae93"},{"id":"DisGeNET5_variant_disease","color":"#9493ec"},{"id":"DisGeNET5_gene_disease","color":"#abec93"},{"id":"tmVarCorpus","color":"#ec93c5"},{"id":"DisGeNET","color":"#93dfec"}]}]}}