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PubMed:15993867 JSONTXT

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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 1055-1062 Glycan_Motif denotes glucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 88-92 http://purl.obolibrary.org/obo/MAT_0000299 denotes bone
T2 97-106 http://purl.obolibrary.org/obo/MAT_0000189 denotes cartilage
T3 419-423 http://purl.obolibrary.org/obo/MAT_0000299 denotes bone
T4 428-437 http://purl.obolibrary.org/obo/MAT_0000189 denotes cartilage
T5 647-651 http://purl.obolibrary.org/obo/MAT_0000299 denotes bone
T6 656-665 http://purl.obolibrary.org/obo/MAT_0000189 denotes cartilage

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-113 Sentence denotes N-Acyl derivatives of glucosamine as acceptor substrates for galactosyltransferase from bone and cartilage cells.
TextSentencer_T2 114-184 Sentence denotes Glucosamine is commonly used as a nutraceutical by arthritis patients.
TextSentencer_T3 185-284 Sentence denotes However, its mode of action is still unknown, and there is controversy about its clinical efficacy.
TextSentencer_T4 285-368 Sentence denotes Synthetic N-acyl glucosamines (acyl group>2 carbons) comprise a new class of drugs.
TextSentencer_T5 369-525 Sentence denotes We examined these derivatives for their effect in bone and cartilage cells, and for their ability to serve as acceptor substrates for galactosyltransferase.
TextSentencer_T6 526-714 Sentence denotes With the exception of N-benzoylglucosamine, compounds of the series were good substrates for galactosyltransferases from bone and cartilage cells, and for purified enzyme from bovine milk.
TextSentencer_T7 715-930 Sentence denotes When N-butyrylglucosamine (GlcNBu) was added to the cell medium of primary bovine chondrocytes and human osteoblasts, small amounts were found to enter the cells and a radiolabeled metabolite appeared in the medium.
TextSentencer_T8 931-1012 Sentence denotes However, GlcNBu did not appear to be incorporated directly into oligosaccharides.
TextSentencer_T9 1013-1209 Sentence denotes GlcNBu at 1 and 5mM concentrations in the glucose-free cell medium of primary human osteoblasts from osteoarthritis patients did not significantly alter cell proliferation or cell differentiation.
T1 0-113 Sentence denotes N-Acyl derivatives of glucosamine as acceptor substrates for galactosyltransferase from bone and cartilage cells.
T2 114-184 Sentence denotes Glucosamine is commonly used as a nutraceutical by arthritis patients.
T3 185-284 Sentence denotes However, its mode of action is still unknown, and there is controversy about its clinical efficacy.
T4 285-368 Sentence denotes Synthetic N-acyl glucosamines (acyl group>2 carbons) comprise a new class of drugs.
T5 369-525 Sentence denotes We examined these derivatives for their effect in bone and cartilage cells, and for their ability to serve as acceptor substrates for galactosyltransferase.
T6 526-714 Sentence denotes With the exception of N-benzoylglucosamine, compounds of the series were good substrates for galactosyltransferases from bone and cartilage cells, and for purified enzyme from bovine milk.
T7 715-930 Sentence denotes When N-butyrylglucosamine (GlcNBu) was added to the cell medium of primary bovine chondrocytes and human osteoblasts, small amounts were found to enter the cells and a radiolabeled metabolite appeared in the medium.
T8 931-1012 Sentence denotes However, GlcNBu did not appear to be incorporated directly into oligosaccharides.
T9 1013-1209 Sentence denotes GlcNBu at 1 and 5mM concentrations in the glucose-free cell medium of primary human osteoblasts from osteoarthritis patients did not significantly alter cell proliferation or cell differentiation.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 1055-1062 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 165-174 Phenotype denotes arthritis HP:0001369
T2 1114-1128 Phenotype denotes osteoarthritis HP:0002758

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 165-174 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T2 1114-1128 Disease denotes osteoarthritis http://purl.obolibrary.org/obo/MONDO_0005178

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 702-708 OrganismTaxon denotes bovine 9913
T2 790-796 OrganismTaxon denotes bovine 9913
T3 814-819 OrganismTaxon denotes human 9606
T4 1091-1096 OrganismTaxon denotes human 9606

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 88-92 Body_part denotes bone http://purl.obolibrary.org/obo/MAT_0000299
T2 97-106 Body_part denotes cartilage http://purl.obolibrary.org/obo/MAT_0000189
T3 419-423 Body_part denotes bone http://purl.obolibrary.org/obo/MAT_0000299
T4 428-437 Body_part denotes cartilage http://purl.obolibrary.org/obo/MAT_0000189
T5 647-651 Body_part denotes bone http://purl.obolibrary.org/obo/MAT_0000299
T6 656-665 Body_part denotes cartilage http://purl.obolibrary.org/obo/MAT_0000189

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 88-92 Body_part denotes bone http://purl.obolibrary.org/obo/UBERON_0001474|http://purl.obolibrary.org/obo/UBERON_0002481
T3 97-112 Body_part denotes cartilage cells http://purl.obolibrary.org/obo/CL_0000138
T4 419-423 Body_part denotes bone http://purl.obolibrary.org/obo/UBERON_0001474|http://purl.obolibrary.org/obo/UBERON_0002481
T6 428-443 Body_part denotes cartilage cells http://purl.obolibrary.org/obo/CL_0000138
T7 647-651 Body_part denotes bone http://purl.obolibrary.org/obo/UBERON_0001474|http://purl.obolibrary.org/obo/UBERON_0002481
T9 656-671 Body_part denotes cartilage cells http://purl.obolibrary.org/obo/CL_0000138
T10 709-713 Body_part denotes milk http://purl.obolibrary.org/obo/UBERON_0001913
T11 797-809 Body_part denotes chondrocytes http://purl.obolibrary.org/obo/CL_0000138
T12 820-831 Body_part denotes osteoblasts http://purl.obolibrary.org/obo/CL_0000062
T13 1097-1108 Body_part denotes osteoblasts http://purl.obolibrary.org/obo/CL_0000062

Glycosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 97-112 Cell denotes cartilage cells http://purl.obolibrary.org/obo/CL:0000138
T2 428-443 Cell denotes cartilage cells http://purl.obolibrary.org/obo/CL:0000138
T3 656-671 Cell denotes cartilage cells http://purl.obolibrary.org/obo/CL:0000138
T4 797-809 Cell denotes chondrocytes http://purl.obolibrary.org/obo/CL:0000138
T5 820-831 Cell denotes osteoblasts http://purl.obolibrary.org/obo/CL:0000062
T6 1097-1108 Cell denotes osteoblasts http://purl.obolibrary.org/obo/CL:0000062