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PubMed:15864433 JSONTXT

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ngly1-sample8

Id Subject Object Predicate Lexical cue
T1 788-811 GO:0006517 denotes protein deglycosylation

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 978-985 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 978-985 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose

NGLY1-deficiency

Id Subject Object Predicate Lexical cue
PD-NGLY1-deficiency-B_T1 22-55 hgnc:24622 denotes endo-beta-N-acetylglucosaminidase
PD-NGLY1-deficiency-B_T2 140-173 hgnc:24622 denotes Endo-beta-N-acetylglucosaminidase
PD-NGLY1-deficiency-B_T3 884-918 hgnc:24622 denotes endo- beta-N-acetylglucosaminidase

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-139 Sentence denotes Mutational studies on endo-beta-N-acetylglucosaminidase D which hydrolyzes core portion of asparagine-linked complex type oligosaccharides.
TextSentencer_T2 140-371 Sentence denotes Endo-beta-N-acetylglucosaminidase D (Endo D) produced by Streptococcus pneumoniae hydrolyzes the di-N-acetylchitobiose structure in the core of complex-type asparagine-linked oligosaccharides, and has a molecular weight of 180 kDa.
TextSentencer_T3 372-521 Sentence denotes A truncated Endo D of 102 kDa in which 134 N-terminal amino acids and 599 C-terminal amino acids were deleted, still retained the enzymatic activity.
TextSentencer_T4 522-699 Sentence denotes The truncated Endo D has specificity indistinguishable from the intact enzyme, and also acted on the core structure of asparagine-linked oligosaccharides attached to intact IgG.
TextSentencer_T5 700-812 Sentence denotes Because of its lower molecular weight, the truncated enzyme may be useful as a tool for protein deglycosylation.
TextSentencer_T6 813-1008 Sentence denotes The entire region of the truncated Endo D had 32% sequence identity to endo- beta-N-acetylglucosaminidase BH (Endo BH) from Bacillus halodurans, which acted on high-mannose type oligosaccharides.
TextSentencer_T7 1009-1084 Sentence denotes Chimeric constructs of the truncated Endo D and Endo BH showed no activity.
TextSentencer_T8 1085-1198 Sentence denotes Glutamic acid 324 (E 324) in Endo D is conserved in Endo BH and Endo M, and is an essential amino acid in Endo M.
TextSentencer_T9 1199-1242 Sentence denotes Mutation of E324 abolished Endo D activity.
TextSentencer_T10 1243-1367 Sentence denotes The specificity of Endo D for complex type oligosaccharides is probably defined by multiple domains in the Endo D structure.
T1 0-139 Sentence denotes Mutational studies on endo-beta-N-acetylglucosaminidase D which hydrolyzes core portion of asparagine-linked complex type oligosaccharides.
T2 140-371 Sentence denotes Endo-beta-N-acetylglucosaminidase D (Endo D) produced by Streptococcus pneumoniae hydrolyzes the di-N-acetylchitobiose structure in the core of complex-type asparagine-linked oligosaccharides, and has a molecular weight of 180 kDa.
T3 372-521 Sentence denotes A truncated Endo D of 102 kDa in which 134 N-terminal amino acids and 599 C-terminal amino acids were deleted, still retained the enzymatic activity.
T4 522-699 Sentence denotes The truncated Endo D has specificity indistinguishable from the intact enzyme, and also acted on the core structure of asparagine-linked oligosaccharides attached to intact IgG.
T5 700-812 Sentence denotes Because of its lower molecular weight, the truncated enzyme may be useful as a tool for protein deglycosylation.
T6 813-1008 Sentence denotes The entire region of the truncated Endo D had 32% sequence identity to endo- beta-N-acetylglucosaminidase BH (Endo BH) from Bacillus halodurans, which acted on high-mannose type oligosaccharides.
T7 1009-1084 Sentence denotes Chimeric constructs of the truncated Endo D and Endo BH showed no activity.
T8 1085-1198 Sentence denotes Glutamic acid 324 (E 324) in Endo D is conserved in Endo BH and Endo M, and is an essential amino acid in Endo M.
T9 1199-1242 Sentence denotes Mutation of E324 abolished Endo D activity.
T10 1243-1367 Sentence denotes The specificity of Endo D for complex type oligosaccharides is probably defined by multiple domains in the Endo D structure.

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 197-221 Disease denotes Streptococcus pneumoniae http://purl.obolibrary.org/obo/MONDO_0005972

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 197-221 OrganismTaxon denotes Streptococcus pneumoniae 1313
T2 937-945 OrganismTaxon denotes Bacillus 1386|55087

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 211-221 Phenotype denotes pneumoniae HP:0002090