PubMed:15749661
Annnotations
PubTator4TogoVar
Id | Subject | Object | Predicate | Lexical cue | proteinmutation |
---|---|---|---|---|---|
15749661_0 | 21-26 | ProteinMutation | denotes | L490R | rs80338886 |
15749661_1 | 169-174 | ProteinMutation | denotes | C282Y | rs1800562 |
15749661_2 | 886-891 | ProteinMutation | denotes | L490R | rs80338886 |
15749661_3 | 968-973 | ProteinMutation | denotes | I238M | rs34242818 |
15749661_4 | 1011-1016 | ProteinMutation | denotes | L490R | rs80338886 |
15749661_5 | 1050-1055 | ProteinMutation | denotes | L490R | rs80338886 |
15749661_6 | 1060-1065 | ProteinMutation | denotes | I238M | rs34242818 |
LitCoin-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-115 | Sentence | denotes | Two novel mutations, L490R and V561X, of the transferrin receptor 2 gene in Japanese patients with hemochromatosis. |
T2 | 116-142 | Sentence | denotes | BACKGROUND AND OBJECTIVES: |
T3 | 143-299 | Sentence | denotes | The low prevalence of the C282Y mutation of the HFE gene in Japan means that the genetic background of hemochromatosis in Japanese patients remains unclear. |
T4 | 300-433 | Sentence | denotes | In a previous report, we showed that 3 patients from one family had an AVAQ 594-597 deletion of the transferrin receptor (TfR2) gene. |
T5 | 434-519 | Sentence | denotes | This suggests that the TfR2 gene is involved in hemochromatosis in Japanese patients. |
T6 | 520-539 | Sentence | denotes | DESIGN AND METHODS: |
T7 | 540-623 | Sentence | denotes | Nine patients clinically diagnosed with hemochromatosis were included in the study. |
T8 | 624-699 | Sentence | denotes | DNA was extracted from whole blood samples collected with informed consent. |
T9 | 700-788 | Sentence | denotes | The HFE and TfR2 genes were analyzed by sequencing the coding region and splicing sites. |
T10 | 789-797 | Sentence | denotes | RESULTS: |
T11 | 798-838 | Sentence | denotes | There were no mutations in the HFE gene. |
T12 | 839-940 | Sentence | denotes | In the TfR2 gene, 2 novel mutations, 1469T->G (L490R) and 1665delC (V561X), were found in 2 patients. |
T13 | 941-1017 | Sentence | denotes | A known variation, 714C-> (I238M), was also found in the patient with L490R. |
T14 | 1018-1144 | Sentence | denotes | The patient homozygous for both L490R and I238M presented with a mild manifestation of hemochromatosis at the age of 41 years. |
T15 | 1145-1281 | Sentence | denotes | His liver was cirrhotic with parenchymal iron deposits and the result of a glucose tolerance test was compatible with diabetes mellitus. |
T16 | 1282-1432 | Sentence | denotes | The patient homozygous for V561X had severe iron overload with the triad of cirrhosis, diabetes mellitus and skin pigmentation at the age of 58 years. |
T17 | 1433-1464 | Sentence | denotes | INTERPRETATION AND CONCLUSIONS: |
T18 | 1465-1605 | Sentence | denotes | Taken together with the previous report, 5 of our 12 patients with hemochromatosis manifesting in middle age had mutations in the TfR2 gene. |
T19 | 1606-1678 | Sentence | denotes | Thus, TfR2 plays a role in the pathogenesis of hemochromatosis in Japan. |
LitCoin-entities
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
1495 | 21-26 | SequenceVariant | denotes | L490R | DBSNP:rs80338886 |
1496 | 31-36 | SequenceVariant | denotes | V561X | DBSNP:rs80338887 |
1497 | 45-67 | GeneOrGeneProduct | denotes | transferrin receptor 2 | NCBIGene:7036 |
1498 | 85-93 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
1499 | 99-114 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | MESH:D006432 |
1500 | 169-174 | SequenceVariant | denotes | C282Y | DBSNP:rs1800562 |
1501 | 191-194 | GeneOrGeneProduct | denotes | HFE | NCBIGene:3077 |
1502 | 246-261 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | MESH:D006432 |
1503 | 274-282 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
1504 | 339-347 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
1505 | 371-392 | SequenceVariant | denotes | AVAQ 594-597 deletion | p|DEL|594_597|AVAQ |
1506 | 400-420 | GeneOrGeneProduct | denotes | transferrin receptor | NCBIGene:7036 |
1507 | 422-426 | GeneOrGeneProduct | denotes | TfR2 | NCBIGene:7036 |
1508 | 457-461 | GeneOrGeneProduct | denotes | TfR2 | NCBIGene:7036 |
1509 | 482-497 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | MESH:D006432 |
1510 | 510-518 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
1511 | 545-553 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
1512 | 580-595 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | MESH:D006432 |
1513 | 704-707 | GeneOrGeneProduct | denotes | HFE | NCBIGene:3077 |
1514 | 712-716 | GeneOrGeneProduct | denotes | TfR2 | NCBIGene:7036 |
1515 | 829-832 | GeneOrGeneProduct | denotes | HFE | NCBIGene:3077 |
1516 | 846-850 | GeneOrGeneProduct | denotes | TfR2 | NCBIGene:7036 |
1517 | 876-884 | SequenceVariant | denotes | 1469T->G | DBSNP:rs80338886 |
1518 | 886-891 | SequenceVariant | denotes | L490R | DBSNP:rs80338886 |
1519 | 897-905 | SequenceVariant | denotes | 1665delC | DBSNP:rs80338887 |
1520 | 907-912 | SequenceVariant | denotes | V561X | DBSNP:rs80338887 |
1521 | 931-939 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
1522 | 960-964 | SequenceVariant | denotes | 714C | DBSNP:rs34242818 |
1523 | 968-973 | SequenceVariant | denotes | I238M | DBSNP:rs34242818 |
1524 | 998-1005 | OrganismTaxon | denotes | patient | NCBITaxon:9606 |
1525 | 1011-1016 | SequenceVariant | denotes | L490R | DBSNP:rs80338886 |
1526 | 1022-1029 | OrganismTaxon | denotes | patient | NCBITaxon:9606 |
1527 | 1050-1055 | SequenceVariant | denotes | L490R | DBSNP:rs80338886 |
1528 | 1060-1065 | SequenceVariant | denotes | I238M | DBSNP:rs34242818 |
1529 | 1105-1120 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | MESH:D006432 |
1530 | 1159-1168 | DiseaseOrPhenotypicFeature | denotes | cirrhotic | MESH:D008103 |
1531 | 1186-1190 | ChemicalEntity | denotes | iron | MESH:D007501 |
1532 | 1220-1227 | ChemicalEntity | denotes | glucose | MESH:D005947 |
1533 | 1263-1280 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | MESH:D003920 |
1534 | 1286-1293 | OrganismTaxon | denotes | patient | NCBITaxon:9606 |
1535 | 1309-1314 | SequenceVariant | denotes | V561X | DBSNP:rs80338887 |
1536 | 1326-1339 | DiseaseOrPhenotypicFeature | denotes | iron overload | MESH:D019190 |
1537 | 1358-1367 | DiseaseOrPhenotypicFeature | denotes | cirrhosis | MESH:D008103 |
1538 | 1369-1386 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | MESH:D003920 |
1539 | 1391-1408 | DiseaseOrPhenotypicFeature | denotes | skin pigmentation | MESH:D010859 |
1540 | 1518-1526 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
1541 | 1532-1547 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | MESH:D006432 |
1542 | 1595-1599 | GeneOrGeneProduct | denotes | TfR2 | NCBIGene:7036 |
1543 | 1612-1616 | GeneOrGeneProduct | denotes | TfR2 | NCBIGene:7036 |
1544 | 1653-1668 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | MESH:D006432 |
LitCoin_Mondo
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 1263-1280 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | 0005015 |
T2 | 1369-1386 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | 0005015 |
LitCoin-SeqVar
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 21-26 | SequenceVariant | denotes | L490R |
T2 | 31-36 | SequenceVariant | denotes | V561X |
T3 | 169-174 | SequenceVariant | denotes | C282Y |
T4 | 384-399 | SequenceVariant | denotes | deletion of the |
T5 | 876-881 | SequenceVariant | denotes | 1469T |
T6 | 886-891 | SequenceVariant | denotes | L490R |
T7 | 897-905 | SequenceVariant | denotes | 1665delC |
T8 | 907-912 | SequenceVariant | denotes | V561X |
T9 | 960-964 | SequenceVariant | denotes | 714C |
T10 | 968-973 | SequenceVariant | denotes | I238M |
T11 | 1011-1016 | SequenceVariant | denotes | L490R |
T12 | 1050-1055 | SequenceVariant | denotes | L490R |
T13 | 1060-1065 | SequenceVariant | denotes | I238M |
T14 | 1309-1314 | SequenceVariant | denotes | V561X |
LitCoin-GeneOrGeneProduct-v0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T15 | 712-716 | GeneOrGeneProduct | denotes | TfR2 |
T1 | 4-9 | GeneOrGeneProduct | denotes | novel |
T2 | 10-19 | GeneOrGeneProduct | denotes | mutations |
T3 | 45-67 | GeneOrGeneProduct | denotes | transferrin receptor 2 |
T4 | 99-114 | GeneOrGeneProduct | denotes | hemochromatosis |
T5 | 175-183 | GeneOrGeneProduct | denotes | mutation |
T6 | 246-261 | GeneOrGeneProduct | denotes | hemochromatosis |
T7 | 291-298 | GeneOrGeneProduct | denotes | unclear |
T8 | 400-420 | GeneOrGeneProduct | denotes | transferrin receptor |
T9 | 422-426 | GeneOrGeneProduct | denotes | TfR2 |
T10 | 457-461 | GeneOrGeneProduct | denotes | TfR2 |
T11 | 482-497 | GeneOrGeneProduct | denotes | hemochromatosis |
T12 | 527-538 | GeneOrGeneProduct | denotes | AND METHODS |
T13 | 540-544 | GeneOrGeneProduct | denotes | Nine |
T14 | 580-595 | GeneOrGeneProduct | denotes | hemochromatosis |
T16 | 773-781 | GeneOrGeneProduct | denotes | splicing |
T17 | 809-821 | GeneOrGeneProduct | denotes | no mutations |
T18 | 846-850 | GeneOrGeneProduct | denotes | TfR2 |
T19 | 851-858 | GeneOrGeneProduct | denotes | gene, 2 |
T20 | 859-864 | GeneOrGeneProduct | denotes | novel |
T21 | 865-874 | GeneOrGeneProduct | denotes | mutations |
T22 | 926-930 | GeneOrGeneProduct | denotes | in 2 |
T33 | 1426-1431 | GeneOrGeneProduct | denotes | years |
T23 | 1105-1120 | GeneOrGeneProduct | denotes | hemochromatosis |
T24 | 1138-1143 | GeneOrGeneProduct | denotes | years |
T25 | 1149-1154 | GeneOrGeneProduct | denotes | liver |
T26 | 1186-1190 | GeneOrGeneProduct | denotes | iron |
T27 | 1228-1237 | GeneOrGeneProduct | denotes | tolerance |
T28 | 1238-1242 | GeneOrGeneProduct | denotes | test |
T29 | 1263-1271 | GeneOrGeneProduct | denotes | diabetes |
T30 | 1326-1330 | GeneOrGeneProduct | denotes | iron |
T31 | 1369-1377 | GeneOrGeneProduct | denotes | diabetes |
T32 | 1391-1395 | GeneOrGeneProduct | denotes | skin |
T34 | 1532-1547 | GeneOrGeneProduct | denotes | hemochromatosis |
T35 | 1578-1587 | GeneOrGeneProduct | denotes | mutations |
T36 | 1595-1599 | GeneOrGeneProduct | denotes | TfR2 |
T37 | 1612-1616 | GeneOrGeneProduct | denotes | TfR2 |
T38 | 1653-1668 | GeneOrGeneProduct | denotes | hemochromatosis |
LitCoin-GeneOrGeneProduct-v2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 4-9 | GeneOrGeneProduct | denotes | novel |
T2 | 45-67 | GeneOrGeneProduct | denotes | transferrin receptor 2 |
T3 | 99-114 | GeneOrGeneProduct | denotes | hemochromatosis |
T4 | 246-261 | GeneOrGeneProduct | denotes | hemochromatosis |
T5 | 291-298 | GeneOrGeneProduct | denotes | unclear |
T6 | 400-420 | GeneOrGeneProduct | denotes | transferrin receptor |
T7 | 482-497 | GeneOrGeneProduct | denotes | hemochromatosis |
T8 | 580-595 | GeneOrGeneProduct | denotes | hemochromatosis |
T9 | 851-858 | GeneOrGeneProduct | denotes | gene, 2 |
T10 | 859-864 | GeneOrGeneProduct | denotes | novel |
T11 | 1105-1120 | GeneOrGeneProduct | denotes | hemochromatosis |
T12 | 1149-1154 | GeneOrGeneProduct | denotes | liver |
T13 | 1263-1271 | GeneOrGeneProduct | denotes | diabetes |
T14 | 1369-1377 | GeneOrGeneProduct | denotes | diabetes |
T15 | 1532-1547 | GeneOrGeneProduct | denotes | hemochromatosis |
T16 | 1653-1668 | GeneOrGeneProduct | denotes | hemochromatosis |
LitCoin-Disease-MeSH
Id | Subject | Object | Predicate | Lexical cue | originalLabel |
---|---|---|---|---|---|
T1 | 99-114 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T2 | 246-261 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T3 | 482-497 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T4 | 580-595 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T5 | 1105-1120 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T6 | 1159-1168 | DiseaseOrPhenotypicFeature | denotes | cirrhotic | DISEASE |
T7 | 1263-1280 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | D003920 |
T8 | 1326-1339 | DiseaseOrPhenotypicFeature | denotes | iron overload | D019190 |
T9 | 1358-1367 | DiseaseOrPhenotypicFeature | denotes | cirrhosis | D005355 |
T10 | 1369-1386 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | D003920 |
T11 | 1532-1547 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T12 | 1653-1668 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
LitCoin-GeneOrGeneProduct-v3
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 45-67 | GeneOrGeneProduct | denotes | transferrin receptor 2 |
T2 | 400-420 | GeneOrGeneProduct | denotes | transferrin receptor |
T3 | 851-858 | GeneOrGeneProduct | denotes | gene, 2 |
LitCoin_Mondo_095
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 99-114 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | 0006507 |
T2 | 246-261 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | 0006507 |
T3 | 482-497 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | 0006507 |
T4 | 580-595 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | 0006507 |
T5 | 1105-1120 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | 0006507 |
T6 | 1263-1280 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | 0005015 |
T7 | 1358-1367 | DiseaseOrPhenotypicFeature | denotes | cirrhosis | 0005155 |
T8 | 1369-1386 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | 0005015 |
T9 | 1391-1395 | DiseaseOrPhenotypicFeature | denotes | skin | 0002531 |
T10 | 1532-1547 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | 0006507 |
T11 | 1653-1668 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | 0006507 |
LitCoin-MeSH-Disease-2
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 99-114 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T2 | 246-261 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T3 | 482-497 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T4 | 580-595 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T5 | 1105-1120 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T6 | 1159-1168 | DiseaseOrPhenotypicFeature | denotes | cirrhotic | DISEASE |
T7 | 1263-1280 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | D003920 |
T8 | 1326-1339 | DiseaseOrPhenotypicFeature | denotes | iron overload | D019190 |
T9 | 1358-1367 | DiseaseOrPhenotypicFeature | denotes | cirrhosis | D005355 |
T10 | 1369-1386 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | D003920 |
T11 | 1391-1408 | DiseaseOrPhenotypicFeature | denotes | skin pigmentation | DISEASE |
T12 | 1532-1547 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T13 | 1653-1668 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
LitCoin-MONDO_bioort2019
Id | Subject | Object | Predicate | Lexical cue | #label |
---|---|---|---|---|---|
T1 | 99-114 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T2 | 246-261 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T3 | 482-497 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T4 | 580-595 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T5 | 1105-1120 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T6 | 1159-1168 | DiseaseOrPhenotypicFeature | denotes | cirrhotic | DISEASE |
T7 | 1263-1280 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | D003920 |
T8 | 1326-1339 | DiseaseOrPhenotypicFeature | denotes | iron overload | D019190 |
T9 | 1358-1367 | DiseaseOrPhenotypicFeature | denotes | cirrhosis | D005355 |
T10 | 1369-1386 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | D003920 |
T11 | 1391-1408 | DiseaseOrPhenotypicFeature | denotes | skin pigmentation | DISEASE |
T12 | 1532-1547 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
T13 | 1653-1668 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 |
LitCoin-Chemical-MeSH-CHEBI
Id | Subject | Object | Predicate | Lexical cue | ID: |
---|---|---|---|---|---|
T1 | 1186-1190 | ChemicalEntity | denotes | iron | D007501|http://purl.obolibrary.org/obo/CHEBI_18248 |
T3 | 1220-1227 | ChemicalEntity | denotes | glucose | D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234 |
T6 | 1326-1330 | ChemicalEntity | denotes | iron | D007501|http://purl.obolibrary.org/obo/CHEBI_18248 |
LitCoin-NCBITaxon-2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 85-93 | OrganismTaxon | denotes | patients |
T2 | 274-282 | OrganismTaxon | denotes | patients |
T3 | 339-347 | OrganismTaxon | denotes | patients |
T4 | 510-518 | OrganismTaxon | denotes | patients |
T5 | 545-553 | OrganismTaxon | denotes | patients |
T6 | 931-939 | OrganismTaxon | denotes | patients |
T7 | 998-1005 | OrganismTaxon | denotes | patient |
T8 | 1022-1029 | OrganismTaxon | denotes | patient |
T9 | 1286-1293 | OrganismTaxon | denotes | patient |
T10 | 1518-1526 | OrganismTaxon | denotes | patients |
LitCoin-training-merged
Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
---|---|---|---|---|---|---|
T6 | 1326-1330 | ChemicalEntity | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248|D007501 | |
T3 | 1220-1227 | ChemicalEntity | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947 | |
T1 | 1186-1190 | ChemicalEntity | denotes | iron | http://purl.obolibrary.org/obo/CHEBI_18248|D007501 | |
T82976 | 851-858 | GeneOrGeneProduct | denotes | gene, 2 | ||
T2 | 400-420 | GeneOrGeneProduct | denotes | transferrin receptor | ||
T2016 | 45-67 | GeneOrGeneProduct | denotes | transferrin receptor 2 | ||
T13 | 1653-1668 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 | |
T12 | 1532-1547 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 | |
T11 | 1391-1408 | DiseaseOrPhenotypicFeature | denotes | skin pigmentation | DISEASE | |
T10 | 1369-1386 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | D003920 | |
T9 | 1358-1367 | DiseaseOrPhenotypicFeature | denotes | cirrhosis | D005355 | |
T8 | 1326-1339 | DiseaseOrPhenotypicFeature | denotes | iron overload | D019190 | |
T7 | 1263-1280 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | D003920 | |
T23640 | 1159-1168 | DiseaseOrPhenotypicFeature | denotes | cirrhotic | DISEASE | |
T5 | 1105-1120 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 | |
T4 | 580-595 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 | |
T97309 | 482-497 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 | |
T52898 | 246-261 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 | |
T55300 | 99-114 | DiseaseOrPhenotypicFeature | denotes | hemochromatosis | D006432 | |
T99738 | 1518-1526 | OrganismTaxon | denotes | patients | ||
T72565 | 1286-1293 | OrganismTaxon | denotes | patient | ||
T6192 | 1022-1029 | OrganismTaxon | denotes | patient | ||
T82401 | 998-1005 | OrganismTaxon | denotes | patient | ||
T56613 | 931-939 | OrganismTaxon | denotes | patients | ||
T30199 | 545-553 | OrganismTaxon | denotes | patients | ||
T50389 | 510-518 | OrganismTaxon | denotes | patients | ||
T40430 | 339-347 | OrganismTaxon | denotes | patients | ||
T25154 | 274-282 | OrganismTaxon | denotes | patients | ||
T51052 | 85-93 | OrganismTaxon | denotes | patients | ||
T14 | 1309-1314 | SequenceVariant | denotes | V561X | ||
T24456 | 1060-1065 | SequenceVariant | denotes | I238M | ||
T56720 | 1050-1055 | SequenceVariant | denotes | L490R | ||
T1932 | 1011-1016 | SequenceVariant | denotes | L490R | ||
T92726 | 968-973 | SequenceVariant | denotes | I238M | ||
T86165 | 960-964 | SequenceVariant | denotes | 714C | ||
T23684 | 907-912 | SequenceVariant | denotes | V561X | ||
T35022 | 897-905 | SequenceVariant | denotes | 1665delC | ||
T86180 | 886-891 | SequenceVariant | denotes | L490R | ||
T91771 | 876-881 | SequenceVariant | denotes | 1469T | ||
T56457 | 384-399 | SequenceVariant | denotes | deletion of the | ||
T25728 | 169-174 | SequenceVariant | denotes | C282Y | ||
T21389 | 31-36 | SequenceVariant | denotes | V561X | ||
T25393 | 21-26 | SequenceVariant | denotes | L490R |
DisGeNET5_variant_disease
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
15749661-1#26#31#geners1800562 | 169-174 | geners1800562 | denotes | C282Y |
15749661-1#103#118#diseaseC0018995 | 246-261 | diseaseC0018995 | denotes | hemochromatosis |
15749661-1#103#118#diseaseC3469186 | 246-261 | diseaseC3469186 | denotes | hemochromatosis |
15749661-10#32#37#geners80338886 | 1050-1055 | geners80338886 | denotes | L490R |
15749661-10#42#47#geners34242818 | 1060-1065 | geners34242818 | denotes | I238M |
15749661-10#87#102#diseaseC0018995 | 1105-1120 | diseaseC0018995 | denotes | hemochromatosis |
15749661-10#87#102#diseaseC3469186 | 1105-1120 | diseaseC3469186 | denotes | hemochromatosis |
15749661-10#87#102#diseaseC0018995 | 1105-1120 | diseaseC0018995 | denotes | hemochromatosis |
15749661-10#87#102#diseaseC3469186 | 1105-1120 | diseaseC3469186 | denotes | hemochromatosis |
26#31#geners1800562103#118#diseaseC0018995 | 15749661-1#26#31#geners1800562 | 15749661-1#103#118#diseaseC0018995 | associated_with | C282Y,hemochromatosis |
26#31#geners1800562103#118#diseaseC3469186 | 15749661-1#26#31#geners1800562 | 15749661-1#103#118#diseaseC3469186 | associated_with | C282Y,hemochromatosis |
32#37#geners8033888687#102#diseaseC0018995 | 15749661-10#32#37#geners80338886 | 15749661-10#87#102#diseaseC0018995 | associated_with | L490R,hemochromatosis |
32#37#geners8033888687#102#diseaseC3469186 | 15749661-10#32#37#geners80338886 | 15749661-10#87#102#diseaseC3469186 | associated_with | L490R,hemochromatosis |
32#37#geners8033888687#102#diseaseC0018995 | 15749661-10#32#37#geners80338886 | 15749661-10#87#102#diseaseC0018995 | associated_with | L490R,hemochromatosis |
32#37#geners8033888687#102#diseaseC3469186 | 15749661-10#32#37#geners80338886 | 15749661-10#87#102#diseaseC3469186 | associated_with | L490R,hemochromatosis |
42#47#geners3424281887#102#diseaseC0018995 | 15749661-10#42#47#geners34242818 | 15749661-10#87#102#diseaseC0018995 | associated_with | I238M,hemochromatosis |
42#47#geners3424281887#102#diseaseC3469186 | 15749661-10#42#47#geners34242818 | 15749661-10#87#102#diseaseC3469186 | associated_with | I238M,hemochromatosis |
42#47#geners3424281887#102#diseaseC0018995 | 15749661-10#42#47#geners34242818 | 15749661-10#87#102#diseaseC0018995 | associated_with | I238M,hemochromatosis |
42#47#geners3424281887#102#diseaseC3469186 | 15749661-10#42#47#geners34242818 | 15749661-10#87#102#diseaseC3469186 | associated_with | I238M,hemochromatosis |
DisGeNET5_gene_disease
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
15749661-0#45#67#gene7036 | 45-67 | gene7036 | denotes | transferrin receptor 2 |
15749661-0#99#114#diseaseC0018995 | 99-114 | diseaseC0018995 | denotes | hemochromatosis |
15749661-0#99#114#diseaseC3469186 | 99-114 | diseaseC3469186 | denotes | hemochromatosis |
15749661-1#48#51#gene3077 | 191-194 | gene3077 | denotes | HFE |
15749661-1#103#118#diseaseC0018995 | 246-261 | diseaseC0018995 | denotes | hemochromatosis |
15749661-1#103#118#diseaseC3469186 | 246-261 | diseaseC3469186 | denotes | hemochromatosis |
45#67#gene703699#114#diseaseC0018995 | 15749661-0#45#67#gene7036 | 15749661-0#99#114#diseaseC0018995 | associated_with | transferrin receptor 2,hemochromatosis |
45#67#gene703699#114#diseaseC3469186 | 15749661-0#45#67#gene7036 | 15749661-0#99#114#diseaseC3469186 | associated_with | transferrin receptor 2,hemochromatosis |
48#51#gene3077103#118#diseaseC0018995 | 15749661-1#48#51#gene3077 | 15749661-1#103#118#diseaseC0018995 | associated_with | HFE,hemochromatosis |
48#51#gene3077103#118#diseaseC3469186 | 15749661-1#48#51#gene3077 | 15749661-1#103#118#diseaseC3469186 | associated_with | HFE,hemochromatosis |
tmVarCorpus
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 21-26 | ProteinMutation:p|SUB|L|490|R | denotes | L490R |
T2 | 31-36 | ProteinMutation:p|SUB|V|561|X | denotes | V561X |
T3 | 169-174 | ProteinMutation:p|SUB|C|282|Y | denotes | C282Y |
T4 | 876-884 | DNAMutation:c|SUB|T|1469|G | denotes | 1469T->G |
T5 | 886-891 | ProteinMutation:p|SUB|L|490|R | denotes | L490R |
T6 | 897-905 | DNAMutation:c|DEL|1665|C | denotes | 1665delC |
T7 | 907-912 | ProteinMutation:p|SUB|V|561|X | denotes | V561X |
T8 | 968-973 | ProteinMutation:p|SUB|I|238|M | denotes | I238M |
T9 | 1011-1016 | ProteinMutation:p|SUB|L|490|R | denotes | L490R |
T10 | 1050-1055 | ProteinMutation:p|SUB|L|490|R | denotes | L490R |
T11 | 1060-1065 | ProteinMutation:p|SUB|I|238|M | denotes | I238M |
T12 | 1309-1314 | ProteinMutation:p|SUB|V|561|X | denotes | V561X |
DisGeNET
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T0 | 1612-1616 | gene:7036 | denotes | TfR2 |
T1 | 1653-1668 | disease:C0018995 | denotes | hemochromatosis |
R1 | T0 | T1 | associated_with | TfR2,hemochromatosis |