PubMed:15112280 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/15112280","sourcedb":"PubMed","sourceid":"15112280","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/15112280","text":"Characterization of FAMPAC, a newly identified human pancreatic carcinoma cell line with a hereditary background.\nBACKGROUND: A novel pancreatic carcinoma cell line, FAMPAC, was identified from investigation of poorly differentiated pancreatic adenocarcinoma cells found in a patient with a familial predisposition to pancreatic carcinoma. A gene responsible for familial pancreatic carcinoma has not been identified to date.\nMETHODS: The FAMPAC cell line was characterized by its morphology, growth rate, tumorigenicity, and chromosomal analysis. Three known tumor suppressor genes, p16/CDKN2, BRCA2, and p53, all of which are important in the development of pancreatic carcinoma and frequently are involved in a variety of cancer syndromes, were analyzed.\nRESULTS: FAMPAC cells grew as an adhering monolayer in culture medium supplemented with 10% fetal bovine serum and formed tumors rapidly in nude mice. The doubling time ranged from 24 to 48 hours. Karyotype analysis demonstrated the complexity of chromosomal deletions and rearrangements. The cells were negative for ductal differentiation markers such as cytokeratin 7 and MUC1, indicating poor differentiation. Analysis of FAMPAC cells revealed overexpression of the mutated p53 gene (exon 5, codon 175: CGC --\u003e CAC), the presence of a homozygous deletion in the p16 gene, and the presence of wild-type BRCA2 in the tested hot spots.\nCONCLUSIONS: To the authors' knowledge, FAMPAC is the first established human pancreatic carcinoma cell line associated with a familial background. FAMPAC is a tumorigenic cell line with a complex molecular pattern of mutations. These findings may be useful in understanding the mechanisms responsible for the development of sporadic or hereditary forms of pancreatic carcinoma.","tracks":[{"project":"performance-test","denotations":[{"id":"PD-UBERON-AE-B_T1","span":{"begin":863,"end":868},"obj":"http://purl.obolibrary.org/obo/UBERON_0001977"}],"attributes":[{"subj":"PD-UBERON-AE-B_T1","pred":"source","obj":"performance-test"}]},{"project":"DisGeNET","denotations":[{"id":"T0","span":{"begin":595,"end":600},"obj":"gene:675"},{"id":"T1","span":{"begin":725,"end":731},"obj":"disease:C1306459"},{"id":"T2","span":{"begin":595,"end":600},"obj":"gene:675"},{"id":"T3","span":{"begin":725,"end":731},"obj":"disease:C0006826"},{"id":"T4","span":{"begin":595,"end":600},"obj":"gene:675"},{"id":"T5","span":{"begin":660,"end":680},"obj":"disease:C0235974"},{"id":"T6","span":{"begin":588,"end":593},"obj":"gene:1029"},{"id":"T7","span":{"begin":725,"end":731},"obj":"disease:C1306459"},{"id":"T8","span":{"begin":588,"end":593},"obj":"gene:1017"},{"id":"T9","span":{"begin":660,"end":680},"obj":"disease:C0235974"},{"id":"T10","span":{"begin":588,"end":593},"obj":"gene:1029"},{"id":"T11","span":{"begin":660,"end":680},"obj":"disease:C0235974"},{"id":"T12","span":{"begin":588,"end":593},"obj":"gene:1029"},{"id":"T13","span":{"begin":725,"end":731},"obj":"disease:C0006826"},{"id":"T14","span":{"begin":588,"end":593},"obj":"gene:1017"},{"id":"T15","span":{"begin":725,"end":731},"obj":"disease:C1306459"},{"id":"T16","span":{"begin":588,"end":593},"obj":"gene:1017"},{"id":"T17","span":{"begin":725,"end":731},"obj":"disease:C0006826"},{"id":"T18","span":{"begin":1363,"end":1368},"obj":"gene:675"},{"id":"T19","span":{"begin":1383,"end":1392},"obj":"disease:C0263214"},{"id":"T20","span":{"begin":1272,"end":1275},"obj":"gene:788"},{"id":"T21","span":{"begin":1383,"end":1392},"obj":"disease:C0263214"},{"id":"T22","span":{"begin":1272,"end":1275},"obj":"gene:760"},{"id":"T23","span":{"begin":1383,"end":1392},"obj":"disease:C0263214"},{"id":"T24","span":{"begin":1235,"end":1238},"obj":"gene:7157"},{"id":"T25","span":{"begin":1383,"end":1392},"obj":"disease:C0263214"}],"relations":[{"id":"R1","pred":"associated_with","subj":"T0","obj":"T1"},{"id":"R2","pred":"associated_with","subj":"T2","obj":"T3"},{"id":"R3","pred":"associated_with","subj":"T4","obj":"T5"},{"id":"R4","pred":"associated_with","subj":"T6","obj":"T7"},{"id":"R5","pred":"associated_with","subj":"T8","obj":"T9"},{"id":"R6","pred":"associated_with","subj":"T10","obj":"T11"},{"id":"R7","pred":"associated_with","subj":"T12","obj":"T13"},{"id":"R8","pred":"associated_with","subj":"T14","obj":"T15"},{"id":"R9","pred":"associated_with","subj":"T16","obj":"T17"},{"id":"R10","pred":"associated_with","subj":"T18","obj":"T19"},{"id":"R11","pred":"associated_with","subj":"T20","obj":"T21"},{"id":"R12","pred":"associated_with","subj":"T22","obj":"T23"},{"id":"R13","pred":"associated_with","subj":"T24","obj":"T25"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"attributes":[{"subj":"T0","pred":"source","obj":"DisGeNET"},{"subj":"T1","pred":"source","obj":"DisGeNET"},{"subj":"T2","pred":"source","obj":"DisGeNET"},{"subj":"T3","pred":"source","obj":"DisGeNET"},{"subj":"T4","pred":"source","obj":"DisGeNET"},{"subj":"T5","pred":"source","obj":"DisGeNET"},{"subj":"T6","pred":"source","obj":"DisGeNET"},{"subj":"T7","pred":"source","obj":"DisGeNET"},{"subj":"T8","pred":"source","obj":"DisGeNET"},{"subj":"T9","pred":"source","obj":"DisGeNET"},{"subj":"T10","pred":"source","obj":"DisGeNET"},{"subj":"T11","pred":"source","obj":"DisGeNET"},{"subj":"T12","pred":"source","obj":"DisGeNET"},{"subj":"T13","pred":"source","obj":"DisGeNET"},{"subj":"T14","pred":"source","obj":"DisGeNET"},{"subj":"T15","pred":"source","obj":"DisGeNET"},{"subj":"T16","pred":"source","obj":"DisGeNET"},{"subj":"T17","pred":"source","obj":"DisGeNET"},{"subj":"T18","pred":"source","obj":"DisGeNET"},{"subj":"T19","pred":"source","obj":"DisGeNET"},{"subj":"T20","pred":"source","obj":"DisGeNET"},{"subj":"T21","pred":"source","obj":"DisGeNET"},{"subj":"T22","pred":"source","obj":"DisGeNET"},{"subj":"T23","pred":"source","obj":"DisGeNET"},{"subj":"T24","pred":"source","obj":"DisGeNET"},{"subj":"T25","pred":"source","obj":"DisGeNET"}]},{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":113},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":114,"end":125},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":126,"end":339},"obj":"Sentence"},{"id":"TextSentencer_T4","span":{"begin":340,"end":425},"obj":"Sentence"},{"id":"TextSentencer_T5","span":{"begin":426,"end":434},"obj":"Sentence"},{"id":"TextSentencer_T6","span":{"begin":435,"end":547},"obj":"Sentence"},{"id":"TextSentencer_T7","span":{"begin":548,"end":757},"obj":"Sentence"},{"id":"TextSentencer_T8","span":{"begin":758,"end":908},"obj":"Sentence"},{"id":"TextSentencer_T9","span":{"begin":909,"end":954},"obj":"Sentence"},{"id":"TextSentencer_T10","span":{"begin":955,"end":1046},"obj":"Sentence"},{"id":"TextSentencer_T11","span":{"begin":1047,"end":1170},"obj":"Sentence"},{"id":"TextSentencer_T12","span":{"begin":1171,"end":1393},"obj":"Sentence"},{"id":"TextSentencer_T13","span":{"begin":1394,"end":1406},"obj":"Sentence"},{"id":"TextSentencer_T14","span":{"begin":1407,"end":1541},"obj":"Sentence"},{"id":"TextSentencer_T15","span":{"begin":1542,"end":1622},"obj":"Sentence"},{"id":"TextSentencer_T16","span":{"begin":1623,"end":1772},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":113},"obj":"Sentence"},{"id":"T2","span":{"begin":114,"end":125},"obj":"Sentence"},{"id":"T3","span":{"begin":126,"end":339},"obj":"Sentence"},{"id":"T4","span":{"begin":340,"end":425},"obj":"Sentence"},{"id":"T5","span":{"begin":426,"end":434},"obj":"Sentence"},{"id":"T6","span":{"begin":435,"end":547},"obj":"Sentence"},{"id":"T7","span":{"begin":548,"end":757},"obj":"Sentence"},{"id":"T8","span":{"begin":758,"end":908},"obj":"Sentence"},{"id":"T9","span":{"begin":909,"end":954},"obj":"Sentence"},{"id":"T10","span":{"begin":955,"end":1046},"obj":"Sentence"},{"id":"T11","span":{"begin":1047,"end":1170},"obj":"Sentence"},{"id":"T12","span":{"begin":1171,"end":1393},"obj":"Sentence"},{"id":"T13","span":{"begin":1394,"end":1406},"obj":"Sentence"},{"id":"T14","span":{"begin":1407,"end":1541},"obj":"Sentence"},{"id":"T15","span":{"begin":1542,"end":1622},"obj":"Sentence"},{"id":"T16","span":{"begin":1623,"end":1772},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"TextSentencer_T1","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T2","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T3","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T4","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T5","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T6","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T7","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T8","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T9","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T10","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T11","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T12","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T13","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T14","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T15","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T16","pred":"source","obj":"sentences"},{"subj":"T1","pred":"source","obj":"sentences"},{"subj":"T2","pred":"source","obj":"sentences"},{"subj":"T3","pred":"source","obj":"sentences"},{"subj":"T4","pred":"source","obj":"sentences"},{"subj":"T5","pred":"source","obj":"sentences"},{"subj":"T6","pred":"source","obj":"sentences"},{"subj":"T7","pred":"source","obj":"sentences"},{"subj":"T8","pred":"source","obj":"sentences"},{"subj":"T9","pred":"source","obj":"sentences"},{"subj":"T10","pred":"source","obj":"sentences"},{"subj":"T11","pred":"source","obj":"sentences"},{"subj":"T12","pred":"source","obj":"sentences"},{"subj":"T13","pred":"source","obj":"sentences"},{"subj":"T14","pred":"source","obj":"sentences"},{"subj":"T15","pred":"source","obj":"sentences"},{"subj":"T16","pred":"source","obj":"sentences"}]},{"project":"PubCasesHPO","denotations":[{"id":"AB1","span":{"begin":145,"end":154},"obj":"HP:0030731"},{"id":"TI1","span":{"begin":64,"end":73},"obj":"HP:0030731"},{"id":"AB2","span":{"begin":233,"end":258},"obj":"HP:0006725"},{"id":"AB3","span":{"begin":329,"end":338},"obj":"HP:0030731"},{"id":"AB4","span":{"begin":383,"end":392},"obj":"HP:0030731"},{"id":"AB5","span":{"begin":671,"end":680},"obj":"HP:0030731"},{"id":"AB6","span":{"begin":1483,"end":1492},"obj":"HP:0030731"},{"id":"AB7","span":{"begin":1762,"end":1771},"obj":"HP:0030731"}],"attributes":[{"subj":"AB1","pred":"source","obj":"PubCasesHPO"},{"subj":"TI1","pred":"source","obj":"PubCasesHPO"},{"subj":"AB2","pred":"source","obj":"PubCasesHPO"},{"subj":"AB3","pred":"source","obj":"PubCasesHPO"},{"subj":"AB4","pred":"source","obj":"PubCasesHPO"},{"subj":"AB5","pred":"source","obj":"PubCasesHPO"},{"subj":"AB6","pred":"source","obj":"PubCasesHPO"},{"subj":"AB7","pred":"source","obj":"PubCasesHPO"}]},{"project":"PubCasesORDO","denotations":[{"id":"AB1","span":{"begin":363,"end":392},"obj":"ORDO:1333"}],"namespaces":[{"prefix":"ORDO","uri":"http://www.orpha.net/ORDO/Orphanet_"}],"attributes":[{"subj":"AB1","pred":"source","obj":"PubCasesORDO"}]},{"project":"DisGeNET5_gene_disease","denotations":[{"id":"15112280-4#40#45#gene1017","span":{"begin":588,"end":593},"obj":"gene1017"},{"id":"15112280-4#40#45#gene1029","span":{"begin":588,"end":593},"obj":"gene1029"},{"id":"15112280-4#47#52#gene675","span":{"begin":595,"end":600},"obj":"gene675"},{"id":"15112280-4#112#132#diseaseC0235974","span":{"begin":660,"end":680},"obj":"diseaseC0235974"},{"id":"15112280-9#64#67#gene7157","span":{"begin":1235,"end":1238},"obj":"gene7157"},{"id":"15112280-9#101#104#gene760","span":{"begin":1272,"end":1275},"obj":"gene760"},{"id":"15112280-9#101#104#gene788","span":{"begin":1272,"end":1275},"obj":"gene788"},{"id":"15112280-9#192#197#gene675","span":{"begin":1363,"end":1368},"obj":"gene675"},{"id":"15112280-9#216#221#diseaseC0015230","span":{"begin":1387,"end":1392},"obj":"diseaseC0015230"},{"id":"15112280-9#216#221#diseaseC0848332","span":{"begin":1387,"end":1392},"obj":"diseaseC0848332"},{"id":"15112280-9#216#221#diseaseC0015230","span":{"begin":1387,"end":1392},"obj":"diseaseC0015230"},{"id":"15112280-9#216#221#diseaseC0848332","span":{"begin":1387,"end":1392},"obj":"diseaseC0848332"},{"id":"15112280-9#216#221#diseaseC0015230","span":{"begin":1387,"end":1392},"obj":"diseaseC0015230"},{"id":"15112280-9#216#221#diseaseC0848332","span":{"begin":1387,"end":1392},"obj":"diseaseC0848332"},{"id":"15112280-9#216#221#diseaseC0015230","span":{"begin":1387,"end":1392},"obj":"diseaseC0015230"},{"id":"15112280-9#216#221#diseaseC0848332","span":{"begin":1387,"end":1392},"obj":"diseaseC0848332"}],"relations":[{"id":"40#45#gene1017112#132#diseaseC0235974","pred":"associated_with","subj":"15112280-4#40#45#gene1017","obj":"15112280-4#112#132#diseaseC0235974"},{"id":"40#45#gene1029112#132#diseaseC0235974","pred":"associated_with","subj":"15112280-4#40#45#gene1029","obj":"15112280-4#112#132#diseaseC0235974"},{"id":"47#52#gene675112#132#diseaseC0235974","pred":"associated_with","subj":"15112280-4#47#52#gene675","obj":"15112280-4#112#132#diseaseC0235974"},{"id":"64#67#gene7157216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#64#67#gene7157","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"64#67#gene7157216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#64#67#gene7157","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"64#67#gene7157216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#64#67#gene7157","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"64#67#gene7157216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#64#67#gene7157","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"64#67#gene7157216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#64#67#gene7157","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"64#67#gene7157216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#64#67#gene7157","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"64#67#gene7157216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#64#67#gene7157","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"64#67#gene7157216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#64#67#gene7157","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"101#104#gene760216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#101#104#gene760","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"101#104#gene760216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#101#104#gene760","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"101#104#gene760216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#101#104#gene760","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"101#104#gene760216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#101#104#gene760","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"101#104#gene760216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#101#104#gene760","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"101#104#gene760216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#101#104#gene760","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"101#104#gene760216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#101#104#gene760","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"101#104#gene760216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#101#104#gene760","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"101#104#gene788216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#101#104#gene788","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"101#104#gene788216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#101#104#gene788","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"101#104#gene788216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#101#104#gene788","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"101#104#gene788216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#101#104#gene788","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"101#104#gene788216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#101#104#gene788","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"101#104#gene788216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#101#104#gene788","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"101#104#gene788216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#101#104#gene788","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"101#104#gene788216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#101#104#gene788","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"192#197#gene675216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#192#197#gene675","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"192#197#gene675216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#192#197#gene675","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"192#197#gene675216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#192#197#gene675","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"192#197#gene675216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#192#197#gene675","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"192#197#gene675216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#192#197#gene675","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"192#197#gene675216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#192#197#gene675","obj":"15112280-9#216#221#diseaseC0848332"},{"id":"192#197#gene675216#221#diseaseC0015230","pred":"associated_with","subj":"15112280-9#192#197#gene675","obj":"15112280-9#216#221#diseaseC0015230"},{"id":"192#197#gene675216#221#diseaseC0848332","pred":"associated_with","subj":"15112280-9#192#197#gene675","obj":"15112280-9#216#221#diseaseC0848332"}],"attributes":[{"subj":"15112280-4#40#45#gene1017","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-4#40#45#gene1029","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-4#47#52#gene675","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-4#112#132#diseaseC0235974","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-9#64#67#gene7157","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-9#101#104#gene760","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-9#101#104#gene788","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-9#192#197#gene675","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-9#216#221#diseaseC0015230","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-9#216#221#diseaseC0848332","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-9#216#221#diseaseC0015230","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-9#216#221#diseaseC0848332","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-9#216#221#diseaseC0015230","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-9#216#221#diseaseC0848332","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-9#216#221#diseaseC0015230","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"15112280-9#216#221#diseaseC0848332","pred":"source","obj":"DisGeNET5_gene_disease"}]},{"project":"PubMed_Structured_Abstracts","denotations":[{"id":"T1","span":{"begin":126,"end":425},"obj":"BACKGROUND"},{"id":"T2","span":{"begin":435,"end":757},"obj":"METHODS"},{"id":"T3","span":{"begin":767,"end":1393},"obj":"RESULTS"},{"id":"T4","span":{"begin":1407,"end":1772},"obj":"CONCLUSIONS"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubMed_Structured_Abstracts"},{"subj":"T2","pred":"source","obj":"PubMed_Structured_Abstracts"},{"subj":"T3","pred":"source","obj":"PubMed_Structured_Abstracts"},{"subj":"T4","pred":"source","obj":"PubMed_Structured_Abstracts"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"performance-test","color":"#a593ec","default":true},{"id":"DisGeNET","color":"#9aec93"},{"id":"sentences","color":"#ec93b4"},{"id":"PubCasesHPO","color":"#93ceec"},{"id":"PubCasesORDO","color":"#e8ec93"},{"id":"DisGeNET5_gene_disease","color":"#d593ec"},{"id":"PubMed_Structured_Abstracts","color":"#93ecbb"}]}]}}