PubMed:14711836
Annnotations
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 129-146 | Cell | denotes | endothelial cells | http://purl.obolibrary.org/obo/CL:0000115 |
| T2 | 321-335 | Cell | denotes | dendritic cell | http://purl.obolibrary.org/obo/CL:0000451|http://purl.obolibrary.org/obo/CL:0001056 |
| T4 | 634-650 | Cell | denotes | endothelial cell | http://purl.obolibrary.org/obo/CL:0000115 |
| T5 | 982-1000 | Cell | denotes | hematopoietic cell | http://purl.obolibrary.org/obo/CL:0000988 |
| T6 | 1014-1046 | Cell | denotes | monocyte-derived dendritic cells | http://purl.obolibrary.org/obo/CL:0011031 |
| T7 | 1014-1022 | Cell | denotes | monocyte | http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054 |
| T9 | 1048-1051 | Cell | denotes | DCs | http://purl.obolibrary.org/obo/CL:0000451 |
| T10 | 1113-1130 | Cell | denotes | endothelial cells | http://purl.obolibrary.org/obo/CL:0000115 |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1210-1217 | Glycan_Motif | denotes | mannose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ |
| T2 | 1231-1237 | Glycan_Motif | denotes | fucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO |
| T3 | 1278-1287 | Glycan_Motif | denotes | galactose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-171 | Sentence | denotes | Characterization of a novel C-type lectin-like gene, LSECtin: demonstration of carbohydrate binding and expression in sinusoidal endothelial cells of liver and lymph node. |
| T2 | 172-450 | Sentence | denotes | A new C-type lectin-like gene encodes 293 amino acids and maps to chromosome 19p13.3 adjacent to the previously described C-type lectin genes, CD23, dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN), and DC-SIGN-related protein (DC-SIGNR). |
| T3 | 451-553 | Sentence | denotes | The four genes form a tight cluster in an insert size of 105 kb and have analogous genomic structures. |
| T4 | 554-860 | Sentence | denotes | The new C-type lectin-like molecule, designated liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin), is a type II integral membrane protein of approximately 40 kDa in size with a single C-type lectin-like domain at the COOH terminus, closest in homology to DC-SIGNR, DC-SIGN, and CD23. |
| T5 | 861-1053 | Sentence | denotes | LSECtin mRNA was only expressed in liver and lymph node among 15 human tissues tested, intriguingly neither expressed on hematopoietic cell lines nor on monocyte-derived dendritic cells (DCs). |
| T6 | 1054-1192 | Sentence | denotes | Moreover, LSECtin is expressed predominantly by sinusoidal endothelial cells of human liver and lymph node and co-expressed with DC-SIGNR. |
| T7 | 1193-1288 | Sentence | denotes | LSECtin binds to mannose, GlcNAc, and fucose in a Ca(2+)-dependent manner but not to galactose. |
| T8 | 1289-1452 | Sentence | denotes | Our results indicate that LSECtin is a novel member of a family of proteins comprising CD23, DC-SIGN, and DC-SIGNR and might function in vivo as a lectin receptor. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1210-1217 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
| T2 | 1231-1237 | https://glytoucan.org/Structures/Glycans/G82576YO | denotes | fucose |
| T3 | 1278-1287 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactose |
| T4 | 1278-1287 | https://glytoucan.org/Structures/Glycans/G68158BT | denotes | galactose |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 150-155 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
| T2 | 160-170 | http://purl.obolibrary.org/obo/MAT_0000197 | denotes | lymph node |
| T3 | 160-170 | http://purl.obolibrary.org/obo/MAT_0000442 | denotes | lymph node |
| T4 | 160-165 | http://purl.obolibrary.org/obo/MAT_0000055 | denotes | lymph |
| T5 | 602-607 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
| T6 | 612-622 | http://purl.obolibrary.org/obo/MAT_0000197 | denotes | lymph node |
| T7 | 612-622 | http://purl.obolibrary.org/obo/MAT_0000442 | denotes | lymph node |
| T8 | 612-617 | http://purl.obolibrary.org/obo/MAT_0000055 | denotes | lymph |
| T9 | 896-901 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
| T10 | 906-916 | http://purl.obolibrary.org/obo/MAT_0000197 | denotes | lymph node |
| T11 | 906-916 | http://purl.obolibrary.org/obo/MAT_0000442 | denotes | lymph node |
| T12 | 906-911 | http://purl.obolibrary.org/obo/MAT_0000055 | denotes | lymph |
| T13 | 1140-1145 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
| T14 | 1150-1160 | http://purl.obolibrary.org/obo/MAT_0000197 | denotes | lymph node |
| T15 | 1150-1160 | http://purl.obolibrary.org/obo/MAT_0000442 | denotes | lymph node |
| T16 | 1150-1155 | http://purl.obolibrary.org/obo/MAT_0000055 | denotes | lymph |
NGLY1-deficiency
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-NGLY1-deficiency-B_T1 | 1219-1225 | chem:24139 | denotes | GlcNAc |
Lectin-Jamboree-small
| Id | Subject | Object | Predicate | Lexical cue | glycosmos_id |
|---|---|---|---|---|---|
| T1 | 401-408 | Lectin | denotes | DC-SIGN | GL_001382 |
| T2 | 415-422 | Lectin | denotes | DC-SIGN | GL_001382 |
| T3 | 842-849 | Lectin | denotes | DC-SIGN | GL_001382 |
| T4 | 1382-1389 | Lectin | denotes | DC-SIGN | GL_001382 |
Lectin-Jamboree-Sentence
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-171 | Sentence | denotes | Characterization of a novel C-type lectin-like gene, LSECtin: demonstration of carbohydrate binding and expression in sinusoidal endothelial cells of liver and lymph node. |
| T2 | 172-450 | Sentence | denotes | A new C-type lectin-like gene encodes 293 amino acids and maps to chromosome 19p13.3 adjacent to the previously described C-type lectin genes, CD23, dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN), and DC-SIGN-related protein (DC-SIGNR). |
| T3 | 451-553 | Sentence | denotes | The four genes form a tight cluster in an insert size of 105 kb and have analogous genomic structures. |
| T4 | 554-860 | Sentence | denotes | The new C-type lectin-like molecule, designated liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin), is a type II integral membrane protein of approximately 40 kDa in size with a single C-type lectin-like domain at the COOH terminus, closest in homology to DC-SIGNR, DC-SIGN, and CD23. |
| T5 | 861-1053 | Sentence | denotes | LSECtin mRNA was only expressed in liver and lymph node among 15 human tissues tested, intriguingly neither expressed on hematopoietic cell lines nor on monocyte-derived dendritic cells (DCs). |
| T6 | 1054-1192 | Sentence | denotes | Moreover, LSECtin is expressed predominantly by sinusoidal endothelial cells of human liver and lymph node and co-expressed with DC-SIGNR. |
| T7 | 1193-1288 | Sentence | denotes | LSECtin binds to mannose, GlcNAc, and fucose in a Ca(2+)-dependent manner but not to galactose. |
| T8 | 1289-1452 | Sentence | denotes | Our results indicate that LSECtin is a novel member of a family of proteins comprising CD23, DC-SIGN, and DC-SIGNR and might function in vivo as a lectin receptor. |
Lectin_function
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 28-41 | GL_000114 | denotes | C-type lectin |
| T2 | 28-41 | GL_000115 | denotes | C-type lectin |
| T3 | 35-41 | GX_000027 | denotes | lectin |
| T4 | 35-41 | GX_000045 | denotes | lectin |
| T5 | 178-191 | GL_000114 | denotes | C-type lectin |
| T6 | 178-191 | GL_000115 | denotes | C-type lectin |
| T7 | 185-191 | GX_000027 | denotes | lectin |
| T8 | 185-191 | GX_000045 | denotes | lectin |
| T9 | 294-307 | GL_000114 | denotes | C-type lectin |
| T10 | 294-307 | GL_000115 | denotes | C-type lectin |
| T11 | 301-307 | GX_000027 | denotes | lectin |
| T12 | 301-307 | GX_000045 | denotes | lectin |
| T13 | 401-408 | GX_000001 | denotes | DC-SIGN |
| T14 | 401-408 | GX_000012 | denotes | DC-SIGN |
| T15 | 401-408 | GX_000016 | denotes | DC-SIGN |
| T16 | 401-408 | GL_001382 | denotes | DC-SIGN |
| T17 | 415-422 | GX_000001 | denotes | DC-SIGN |
| T18 | 415-422 | GX_000012 | denotes | DC-SIGN |
| T19 | 415-422 | GX_000016 | denotes | DC-SIGN |
| T20 | 415-422 | GL_001382 | denotes | DC-SIGN |
| T21 | 562-575 | GL_000114 | denotes | C-type lectin |
| T22 | 562-575 | GL_000115 | denotes | C-type lectin |
| T23 | 569-575 | GX_000027 | denotes | lectin |
| T24 | 569-575 | GX_000045 | denotes | lectin |
| T25 | 651-664 | GL_000114 | denotes | C-type lectin |
| T26 | 651-664 | GL_000115 | denotes | C-type lectin |
| T27 | 658-664 | GX_000027 | denotes | lectin |
| T28 | 658-664 | GX_000045 | denotes | lectin |
| T29 | 761-774 | GL_000114 | denotes | C-type lectin |
| T30 | 761-774 | GL_000115 | denotes | C-type lectin |
| T31 | 768-774 | GX_000027 | denotes | lectin |
| T32 | 768-774 | GX_000045 | denotes | lectin |
| T33 | 842-849 | GX_000001 | denotes | DC-SIGN |
| T34 | 842-849 | GX_000012 | denotes | DC-SIGN |
| T35 | 842-849 | GX_000016 | denotes | DC-SIGN |
| T36 | 842-849 | GL_001382 | denotes | DC-SIGN |
| T37 | 1382-1389 | GX_000001 | denotes | DC-SIGN |
| T38 | 1382-1389 | GX_000012 | denotes | DC-SIGN |
| T39 | 1382-1389 | GX_000016 | denotes | DC-SIGN |
| T40 | 1382-1389 | GL_001382 | denotes | DC-SIGN |
| T41 | 1436-1442 | GX_000027 | denotes | lectin |
| T42 | 1436-1442 | GX_000045 | denotes | lectin |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 926-931 | OrganismTaxon | denotes | human | 9606 |
| T2 | 1134-1139 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 129-146 | Body_part | denotes | endothelial cells | http://purl.obolibrary.org/obo/CL_0000115 |
| T2 | 150-155 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T3 | 160-170 | Body_part | denotes | lymph node | http://purl.obolibrary.org/obo/UBERON_0000029 |
| T4 | 238-248 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |
| T5 | 321-335 | Body_part | denotes | dendritic cell | http://purl.obolibrary.org/obo/CL_0000451 |
| T6 | 602-607 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T7 | 612-622 | Body_part | denotes | lymph node | http://purl.obolibrary.org/obo/UBERON_0000029 |
| T8 | 634-650 | Body_part | denotes | endothelial cell | http://purl.obolibrary.org/obo/CL_0000115 |
| T9 | 698-706 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T12 | 896-901 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T13 | 906-916 | Body_part | denotes | lymph node | http://purl.obolibrary.org/obo/UBERON_0000029 |
| T14 | 982-1000 | Body_part | denotes | hematopoietic cell | http://purl.obolibrary.org/obo/CL_0000988 |
| T15 | 1014-1022 | Body_part | denotes | monocyte | http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054 |
| T17 | 1031-1046 | Body_part | denotes | dendritic cells | http://purl.obolibrary.org/obo/CL_0000451 |
| T18 | 1048-1051 | Body_part | denotes | DCs | http://purl.obolibrary.org/obo/CL_0000451 |
| T19 | 1113-1130 | Body_part | denotes | endothelial cells | http://purl.obolibrary.org/obo/CL_0000115 |
| T20 | 1140-1145 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T21 | 1150-1160 | Body_part | denotes | lymph node | http://purl.obolibrary.org/obo/UBERON_0000029 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 150-155 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T2 | 160-170 | Body_part | denotes | lymph node | http://purl.obolibrary.org/obo/MAT_0000197|http://purl.obolibrary.org/obo/MAT_0000442 |
| T4 | 602-607 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T5 | 612-622 | Body_part | denotes | lymph node | http://purl.obolibrary.org/obo/MAT_0000197|http://purl.obolibrary.org/obo/MAT_0000442 |
| T7 | 896-901 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T8 | 906-916 | Body_part | denotes | lymph node | http://purl.obolibrary.org/obo/MAT_0000197|http://purl.obolibrary.org/obo/MAT_0000442 |
| T10 | 1140-1145 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T11 | 1150-1160 | Body_part | denotes | lymph node | http://purl.obolibrary.org/obo/MAT_0000197|http://purl.obolibrary.org/obo/MAT_0000442 |