PubMed:14707483
Annnotations
GlyCosmos6-Glycan-Motif-Image
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 0-7 | Glycan_Motif | denotes | Heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
T3 | 97-104 | Glycan_Motif | denotes | Heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
T5 | 252-259 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
T7 | 353-360 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
T9 | 625-632 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
T11 | 697-704 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
T13 | 873-880 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
T15 | 909-916 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
GlyCosmos6-Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-7 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | Heparin |
T2 | 0-7 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | Heparin |
T3 | 97-104 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | Heparin |
T4 | 97-104 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | Heparin |
T5 | 252-259 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
T6 | 252-259 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
T7 | 353-360 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
T8 | 353-360 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
T9 | 625-632 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
T10 | 625-632 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
T11 | 697-704 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
T12 | 697-704 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
T13 | 873-880 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
T14 | 873-880 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
T15 | 909-916 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
T16 | 909-916 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
TextSentencer_T1 | 0-96 | Sentence | denotes | Heparin inhibits the reconstituted plasma membrane Ca(2+)-ATPase from porcine brain synaptosome. |
TextSentencer_T2 | 97-219 | Sentence | denotes | Heparin has been shown to be involved in the regulation of cellular Ca(2+) by binding to many proteins with high affinity. |
TextSentencer_T3 | 220-328 | Sentence | denotes | Here we examined the effects of heparin on the plasma membrane Ca(2+)-ATPase from porcine brain synaptosome. |
TextSentencer_T4 | 329-463 | Sentence | denotes | Our results showed that heparin dramatically inhibited the ATP hydrolysis and Ca(2+) uptake in the presence and absence of calmodulin. |
TextSentencer_T5 | 464-644 | Sentence | denotes | Together with controlled proteolysis by trypsin, we concluded that the calmodulin-binding domain of the plasma membrane Ca(2+)-ATPase was less important for the heparin inhibition. |
TextSentencer_T6 | 645-716 | Sentence | denotes | Excess phosphatidylserine was able to eliminate the heparin inhibition. |
TextSentencer_T7 | 717-881 | Sentence | denotes | We observed that Ca(2+) affinity kept no obvious changes, but the ATP affinity of plasma membrane Ca(2+)-ATPase was apparently decreased in the presence of heparin. |
TextSentencer_T8 | 882-981 | Sentence | denotes | Our results indicated that heparin had little effects on ATP or Ca(2+) binding sites of the enzyme. |
T1 | 0-96 | Sentence | denotes | Heparin inhibits the reconstituted plasma membrane Ca(2+)-ATPase from porcine brain synaptosome. |
T2 | 97-219 | Sentence | denotes | Heparin has been shown to be involved in the regulation of cellular Ca(2+) by binding to many proteins with high affinity. |
T3 | 220-328 | Sentence | denotes | Here we examined the effects of heparin on the plasma membrane Ca(2+)-ATPase from porcine brain synaptosome. |
T4 | 329-463 | Sentence | denotes | Our results showed that heparin dramatically inhibited the ATP hydrolysis and Ca(2+) uptake in the presence and absence of calmodulin. |
T5 | 464-644 | Sentence | denotes | Together with controlled proteolysis by trypsin, we concluded that the calmodulin-binding domain of the plasma membrane Ca(2+)-ATPase was less important for the heparin inhibition. |
T6 | 645-716 | Sentence | denotes | Excess phosphatidylserine was able to eliminate the heparin inhibition. |
T7 | 717-881 | Sentence | denotes | We observed that Ca(2+) affinity kept no obvious changes, but the ATP affinity of plasma membrane Ca(2+)-ATPase was apparently decreased in the presence of heparin. |
T8 | 882-981 | Sentence | denotes | Our results indicated that heparin had little effects on ATP or Ca(2+) binding sites of the enzyme. |
Glycosmos6-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 78-83 | http://purl.obolibrary.org/obo/MAT_0000098 | denotes | brain |
T2 | 310-315 | http://purl.obolibrary.org/obo/MAT_0000098 | denotes | brain |
Anatomy-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 35-50 | Body_part | denotes | plasma membrane | http://purl.obolibrary.org/obo/GO_0005886 |
T2 | 78-83 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
T4 | 267-282 | Body_part | denotes | plasma membrane | http://purl.obolibrary.org/obo/GO_0005886 |
T5 | 310-315 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
T7 | 568-583 | Body_part | denotes | plasma membrane | http://purl.obolibrary.org/obo/GO_0005886 |
T8 | 799-814 | Body_part | denotes | plasma membrane | http://purl.obolibrary.org/obo/GO_0005886 |
Anatomy-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 78-83 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
T2 | 310-315 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |