> top > docs > PubMed:1349016 > annotations

PubMed:1349016 JSONTXT

Annnotations TAB JSON ListView MergeView

sentences

Id Subject Object Predicate Lexical cue
T1 0-131 Sentence denotes Stable expression of HB24, a diverged human homeobox gene, in T lymphocytes induces genes involved in T cell activation and growth.
T2 132-306 Sentence denotes A diverged homeobox gene, HB24, which is known to be induced following lymphocyte activation, was introduced into Jurkat T cells under the control of a constitutive promoter.
T3 307-460 Sentence denotes Stable transfectants of HB24 were established that expressed high levels of HB24 mRNA and possessed an altered phenotype suggestive of activated T cells.
T4 461-713 Sentence denotes A number of genes known to be induced following T cell activation and associated with cell growth were increased in the transfectants, including c-fos, c-myc, c-myb, HLA-DR, lck, NF-kappa B, interleukin-2 and interleukin-2 receptor alpha (IL-2R alpha).
T5 714-1014 Sentence denotes Analysis of IL-2R alpha expression by transient transfection of IL-2R alpha promoter constructs into the HB24 transfectants revealed constitutive expression (about 60% of phytohemagglutinin- and phorbol ester-activated Jurkat cells) that was dependent on the kappa B site in the IL-2R alpha promoter.
T6 1015-1160 Sentence denotes Furthermore, as a consequence of the increased HB24 mRNA levels, the Jurkat HB24 transfectants proliferated more rapidly than control cell lines.
T7 1161-1346 Sentence denotes Thus, stable expression of HB24 confers an activation phenotype on a human T cell line, implicating this gene as an important transcriptional factor during T cell activation and growth.
T1 0-131 Sentence denotes Stable expression of HB24, a diverged human homeobox gene, in T lymphocytes induces genes involved in T cell activation and growth.
T2 132-306 Sentence denotes A diverged homeobox gene, HB24, which is known to be induced following lymphocyte activation, was introduced into Jurkat T cells under the control of a constitutive promoter.
T3 307-460 Sentence denotes Stable transfectants of HB24 were established that expressed high levels of HB24 mRNA and possessed an altered phenotype suggestive of activated T cells.
T4 461-713 Sentence denotes A number of genes known to be induced following T cell activation and associated with cell growth were increased in the transfectants, including c-fos, c-myc, c-myb, HLA-DR, lck, NF-kappa B, interleukin-2 and interleukin-2 receptor alpha (IL-2R alpha).
T5 714-1014 Sentence denotes Analysis of IL-2R alpha expression by transient transfection of IL-2R alpha promoter constructs into the HB24 transfectants revealed constitutive expression (about 60% of phytohemagglutinin- and phorbol ester-activated Jurkat cells) that was dependent on the kappa B site in the IL-2R alpha promoter.
T6 1015-1160 Sentence denotes Furthermore, as a consequence of the increased HB24 mRNA levels, the Jurkat HB24 transfectants proliferated more rapidly than control cell lines.
T7 1161-1346 Sentence denotes Thus, stable expression of HB24 confers an activation phenotype on a human T cell line, implicating this gene as an important transcriptional factor during T cell activation and growth.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 21-25 DNA denotes HB24
T2 29-57 DNA denotes diverged human homeobox gene
T3 134-156 DNA denotes diverged homeobox gene
T4 158-162 DNA denotes HB24
T5 246-260 cell_line denotes Jurkat T cells
T6 284-305 DNA denotes constitutive promoter
T7 331-335 DNA denotes HB24
T8 383-392 RNA denotes HB24 mRNA
T9 442-459 cell_type denotes activated T cells
T10 581-594 cell_line denotes transfectants
T11 606-611 DNA denotes c-fos
T12 613-618 DNA denotes c-myc
T13 620-625 DNA denotes c-myb
T14 627-633 DNA denotes HLA-DR
T15 635-638 DNA denotes lck
T16 640-650 protein denotes NF-kappa B
T17 652-665 DNA denotes interleukin-2
T18 670-698 DNA denotes interleukin-2 receptor alpha
T19 700-711 DNA denotes IL-2R alpha
T20 726-737 protein denotes IL-2R alpha
T21 778-809 DNA denotes IL-2R alpha promoter constructs
T22 819-837 cell_line denotes HB24 transfectants
T23 885-945 cell_line denotes phytohemagglutinin- and phorbol ester-activated Jurkat cells
T24 973-985 DNA denotes kappa B site
T25 993-1013 DNA denotes IL-2R alpha promoter
T26 1062-1071 RNA denotes HB24 mRNA
T27 1084-1109 cell_line denotes Jurkat HB24 transfectants
T28 1141-1159 cell_line denotes control cell lines
T29 1188-1192 DNA denotes HB24
T30 1230-1247 cell_line denotes human T cell line
T31 1287-1309 protein denotes transcriptional factor

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-131 Sentence denotes Stable expression of HB24, a diverged human homeobox gene, in T lymphocytes induces genes involved in T cell activation and growth.
S2 132-306 Sentence denotes A diverged homeobox gene, HB24, which is known to be induced following lymphocyte activation, was introduced into Jurkat T cells under the control of a constitutive promoter.
S3 307-460 Sentence denotes Stable transfectants of HB24 were established that expressed high levels of HB24 mRNA and possessed an altered phenotype suggestive of activated T cells.
S4 461-713 Sentence denotes A number of genes known to be induced following T cell activation and associated with cell growth were increased in the transfectants, including c-fos, c-myc, c-myb, HLA-DR, lck, NF-kappa B, interleukin-2 and interleukin-2 receptor alpha (IL-2R alpha).
S5 714-1014 Sentence denotes Analysis of IL-2R alpha expression by transient transfection of IL-2R alpha promoter constructs into the HB24 transfectants revealed constitutive expression (about 60% of phytohemagglutinin- and phorbol ester-activated Jurkat cells) that was dependent on the kappa B site in the IL-2R alpha promoter.
S6 1015-1160 Sentence denotes Furthermore, as a consequence of the increased HB24 mRNA levels, the Jurkat HB24 transfectants proliferated more rapidly than control cell lines.
S7 1161-1346 Sentence denotes Thus, stable expression of HB24 confers an activation phenotype on a human T cell line, implicating this gene as an important transcriptional factor during T cell activation and growth.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 21-25 NP denotes HB24
C2 27-57 NP denotes a diverged human homeobox gene
C3 62-75 NP denotes T lymphocytes
C4 102-130 NP denotes T cell activation and growth
C5 132-156 NP denotes A diverged homeobox gene
C6 158-162 NP denotes HB24
C7 164-169 NP denotes which
C8 246-260 NP denotes Jurkat T cells
C10 331-335 NP denotes HB24
C9 307-335 NP denotes Stable transfectants of HB24
C11 368-392 NP denotes high levels of HB24 mRNA
C12 577-594 NP denotes the transfectants
C13 670-712 NP denotes interleukin-2 receptor alpha (IL-2R alpha)
C14 726-748 NP denotes IL-2R alpha expression
C15 778-809 NP denotes IL-2R alpha promoter constructs
C16 815-837 NP denotes the HB24 transfectants
C17 989-1013 NP denotes the IL-2R alpha promoter
C18 1048-1078 NP denotes the increased HB24 mRNA levels
C19 1080-1109 NP denotes the Jurkat HB24 transfectants
C20 1188-1192 NP denotes HB24
C21 1261-1270 NP denotes this gene
C22 1317-1345 NP denotes T cell activation and growth
R1 C2 C1 coref-appos a diverged human homeobox gene,HB24
R2 C5 C2 coref-ident A diverged homeobox gene,a diverged human homeobox gene
R3 C6 C5 coref-appos HB24,A diverged homeobox gene
R4 C7 C6 coref-relat which,HB24
R5 C8 C3 coref-other Jurkat T cells,T lymphocytes
R6 C10 C6 coref-ident HB24,HB24
R7 C12 C9 coref-ident the transfectants,Stable transfectants of HB24
R8 C14 C13 coref-other IL-2R alpha expression,interleukin-2 receptor alpha (IL-2R alpha)
R9 C16 C12 coref-ident the HB24 transfectants,the transfectants
R10 C17 C15 coref-other the IL-2R alpha promoter,IL-2R alpha promoter constructs
R11 C18 C11 coref-other the increased HB24 mRNA levels,high levels of HB24 mRNA
R12 C19 C16 coref-other the Jurkat HB24 transfectants,the HB24 transfectants
R13 C20 C10 coref-ident HB24,HB24
R14 C21 C20 coref-ident this gene,HB24
R15 C22 C4 coref-ident T cell activation and growth,T cell activation and growth

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 21-25 DNA_domain_or_region denotes HB24
T2 29-57 DNA_family_or_group denotes diverged human homeobox gene
T3 134-156 DNA_family_or_group denotes diverged homeobox gene
T4 158-162 DNA_domain_or_region denotes HB24
T5 203-224 other_name denotes lymphocyte activation
T6 246-260 cell_line denotes Jurkat T cells
T7 284-305 DNA_domain_or_region denotes constitutive promoter
T8 331-335 DNA_domain_or_region denotes HB24
T9 383-392 RNA_molecule denotes HB24 mRNA
T10 442-459 cell_type denotes activated T cells
T11 509-526 other_name denotes T cell activation
T12 547-558 other_name denotes cell growth
T13 581-594 cell_line denotes transfectants
T14 606-611 DNA_domain_or_region denotes c-fos
T15 613-618 DNA_domain_or_region denotes c-myc
T16 620-625 DNA_domain_or_region denotes c-myb
T17 627-633 DNA_domain_or_region denotes HLA-DR
T18 635-638 DNA_domain_or_region denotes lck
T19 640-650 protein_molecule denotes NF-kappa B
T20 652-665 DNA_domain_or_region denotes interleukin-2
T21 670-698 DNA_domain_or_region denotes interleukin-2 receptor alpha
T22 700-711 DNA_domain_or_region denotes IL-2R alpha
T23 726-737 protein_molecule denotes IL-2R alpha
T24 752-774 other_name denotes transient transfection
T25 778-809 DNA_molecule denotes IL-2R alpha promoter constructs
T26 819-823 DNA_domain_or_region denotes HB24
T27 847-870 other_name denotes constitutive expression
T28 973-985 DNA_domain_or_region denotes kappa B site
T29 993-1013 DNA_domain_or_region denotes IL-2R alpha promoter
T30 1062-1071 RNA_molecule denotes HB24 mRNA
T31 1084-1090 cell_line denotes Jurkat
T32 1091-1095 DNA_domain_or_region denotes HB24
T33 1141-1159 cell_line denotes control cell lines
T34 1188-1192 DNA_domain_or_region denotes HB24
T35 1204-1224 other_name denotes activation phenotype
T36 1230-1247 cell_line denotes human T cell line
T37 1287-1309 protein_molecule denotes transcriptional factor

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 38-43 OrganismTaxon denotes human 9606
T2 1230-1235 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 62-75 Body_part denotes T lymphocytes http://purl.obolibrary.org/obo/CL_0000084
T2 102-108 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T3 203-213 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T4 509-515 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T5 1236-1242 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T6 1317-1323 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 62-75 Cell denotes T lymphocytes http://purl.obolibrary.org/obo/CL:0000084
T2 102-108 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T3 203-213 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T4 253-260 Cell denotes T cells http://purl.obolibrary.org/obo/CL:0000084
T5 452-459 Cell denotes T cells http://purl.obolibrary.org/obo/CL:0000084
T6 509-515 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T7 1236-1242 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T8 1317-1323 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084