PubMed:1339443
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 154-161 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T3 | 163-177 | Glycan_Motif | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
| T4 | 170-177 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T6 | 193-207 | Glycan_Motif | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
| T7 | 200-207 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T9 | 616-623 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T11 | 665-679 | Glycan_Motif | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
| T12 | 672-679 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T14 | 754-768 | Glycan_Motif | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
| T15 | 761-768 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-90 | Sentence | denotes | Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. |
| T2 | 91-217 | Sentence | denotes | Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes. |
| T3 | 218-389 | Sentence | denotes | We and others have previously described the isolation of three human alpha (1,3)fucosyltransferase genes which form the basis of a nascent glycosyltransferase gene family. |
| T4 | 390-505 | Sentence | denotes | We now report the molecular cloning and expression of a fourth homologous human alpha (1,3)fucosyltransferase gene. |
| T5 | 506-885 | Sentence | denotes | When transfected into mammalian cells, this fucosyltransferase gene is capable of directing expression of the Lewis x (Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc), sialyl Lewis x (NeuNAc alpha 2-->3Gal beta 1-->4 [Fuc alpha 1-->3]GlcNAc), and difucosyl sialyl Lewis x (NeuNAc alpha 2-->3Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc beta 1-->3 Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc) epitopes. |
| T6 | 886-1045 | Sentence | denotes | The enzyme shares 85% amino acid sequence identity with Fuc-TIII and 89% identity with Fuc-TV but differs substantially in its acceptor substrate requirements. |
| T7 | 1046-1159 | Sentence | denotes | Polymerase chain reaction analyses demonstrate that the gene is syntenic to Fuc-TIII and Fuc-TV on chromosome 19. |
| T8 | 1160-1372 | Sentence | denotes | Southern blot analyses of human genomic DNA demonstrate that these four alpha (1,3)fucosyltransferase genes account for all DNA sequences that cross-hybridize at low stringency with the Fuc-TIII catalytic domain. |
| T9 | 1373-1552 | Sentence | denotes | Using similar methods, a catalytic domain probe from Fuc-TIV identifies a new class of DNA fragments which do not cross-hybridize with the chromosome 19 fucosyltransferase probes. |
| T10 | 1553-1723 | Sentence | denotes | These results extend the molecular definition of a family of human alpha (1,3)fucosyltransferase genes and provide tools for examining fucosyltransferase gene expression. |
| T1 | 0-90 | Sentence | denotes | Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. |
| T2 | 91-217 | Sentence | denotes | Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes. |
| T3 | 218-389 | Sentence | denotes | We and others have previously described the isolation of three human alpha (1,3)fucosyltransferase genes which form the basis of a nascent glycosyltransferase gene family. |
| T4 | 390-505 | Sentence | denotes | We now report the molecular cloning and expression of a fourth homologous human alpha (1,3)fucosyltransferase gene. |
| T5 | 506-885 | Sentence | denotes | When transfected into mammalian cells, this fucosyltransferase gene is capable of directing expression of the Lewis x (Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc), sialyl Lewis x (NeuNAc alpha 2-->3Gal beta 1-->4 [Fuc alpha 1-->3]GlcNAc), and difucosyl sialyl Lewis x (NeuNAc alpha 2-->3Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc beta 1-->3 Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc) epitopes. |
| T6 | 886-1045 | Sentence | denotes | The enzyme shares 85% amino acid sequence identity with Fuc-TIII and 89% identity with Fuc-TV but differs substantially in its acceptor substrate requirements. |
| T7 | 1046-1159 | Sentence | denotes | Polymerase chain reaction analyses demonstrate that the gene is syntenic to Fuc-TIII and Fuc-TV on chromosome 19. |
| T8 | 1160-1372 | Sentence | denotes | Southern blot analyses of human genomic DNA demonstrate that these four alpha (1,3)fucosyltransferase genes account for all DNA sequences that cross-hybridize at low stringency with the Fuc-TIII catalytic domain. |
| T9 | 1373-1552 | Sentence | denotes | Using similar methods, a catalytic domain probe from Fuc-TIV identifies a new class of DNA fragments which do not cross-hybridize with the chromosome 19 fucosyltransferase probes. |
| T10 | 1553-1723 | Sentence | denotes | These results extend the molecular definition of a family of human alpha (1,3)fucosyltransferase genes and provide tools for examining fucosyltransferase gene expression. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 154-161 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T2 | 154-161 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T3 | 163-177 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
| T4 | 170-177 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T5 | 170-177 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T6 | 193-207 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
| T7 | 200-207 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T8 | 200-207 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T9 | 616-623 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T10 | 616-623 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T11 | 665-679 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
| T12 | 672-679 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T13 | 672-679 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T14 | 754-768 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl Lewis x |
| T15 | 761-768 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T16 | 761-768 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 154-161 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T2 | 163-177 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
| T3 | 170-177 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T4 | 193-207 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
| T5 | 200-207 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T6 | 616-623 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T7 | 665-679 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
| T8 | 672-679 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T9 | 754-768 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl Lewis x |
| T10 | 761-768 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
NGLY1-deficiency
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-NGLY1-deficiency-B_T1 | 656-662 | chem:24139 | denotes | GlcNAc |
| PD-NGLY1-deficiency-B_T2 | 731-737 | chem:24139 | denotes | GlcNAc |
| PD-NGLY1-deficiency-B_T3 | 819-825 | chem:24139 | denotes | GlcNAc |
| PD-NGLY1-deficiency-B_T4 | 868-874 | chem:24139 | denotes | GlcNAc |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 154-161 | Glycan | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO |
| T2 | 163-177 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T3 | 193-207 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T4 | 616-623 | Glycan | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO |
| T5 | 665-679 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T6 | 681-687 | Glycan | denotes | NeuNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
| T7 | 754-768 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T8 | 770-776 | Glycan | denotes | NeuNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 154-161 | Glycan | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO |
| T2 | 163-177 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T3 | 193-207 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T4 | 616-623 | Glycan | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO |
| T5 | 665-679 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T6 | 681-687 | Glycan | denotes | NeuNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
| T7 | 754-768 | Glycan | denotes | sialyl Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T8 | 770-776 | Glycan | denotes | NeuNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 154-161 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis x | http://www.glycoepitope.jp/epitopes/EP0011 |
| T2 | 163-177 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T3 | 193-207 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T4 | 616-623 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis x | http://www.glycoepitope.jp/epitopes/EP0011 |
| T5 | 665-679 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T6 | 754-768 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1145-1155 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |
| T2 | 1512-1522 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 154-161 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis x | http://www.glycoepitope.jp/epitopes/EP0011 |
| T2 | 163-177 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T3 | 193-207 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T4 | 616-623 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis x | http://www.glycoepitope.jp/epitopes/EP0011 |
| T5 | 665-679 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T6 | 754-768 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 42-47 | Organism | denotes | human | 9606 |
| T2 | 281-286 | Organism | denotes | human | 9606 |
| T3 | 464-469 | Organism | denotes | human | 9606 |
| T4 | 528-537 | Organism | denotes | mammalian | 40674 |
| T5 | 1186-1191 | Organism | denotes | human | 9606 |
| T6 | 1614-1619 | Organism | denotes | human | 9606 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-90 | Sentence | denotes | Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. |
| T2 | 91-217 | Sentence | denotes | Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes. |
| T3 | 218-389 | Sentence | denotes | We and others have previously described the isolation of three human alpha (1,3)fucosyltransferase genes which form the basis of a nascent glycosyltransferase gene family. |
| T4 | 390-505 | Sentence | denotes | We now report the molecular cloning and expression of a fourth homologous human alpha (1,3)fucosyltransferase gene. |
| T5 | 506-885 | Sentence | denotes | When transfected into mammalian cells, this fucosyltransferase gene is capable of directing expression of the Lewis x (Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc), sialyl Lewis x (NeuNAc alpha 2-->3Gal beta 1-->4 [Fuc alpha 1-->3]GlcNAc), and difucosyl sialyl Lewis x (NeuNAc alpha 2-->3Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc beta 1-->3 Gal beta 1-->4[Fuc alpha 1-->3]GlcNAc) epitopes. |
| T6 | 886-1045 | Sentence | denotes | The enzyme shares 85% amino acid sequence identity with Fuc-TIII and 89% identity with Fuc-TV but differs substantially in its acceptor substrate requirements. |
| T7 | 1046-1159 | Sentence | denotes | Polymerase chain reaction analyses demonstrate that the gene is syntenic to Fuc-TIII and Fuc-TV on chromosome 19. |
| T8 | 1160-1372 | Sentence | denotes | Southern blot analyses of human genomic DNA demonstrate that these four alpha (1,3)fucosyltransferase genes account for all DNA sequences that cross-hybridize at low stringency with the Fuc-TIII catalytic domain. |
| T9 | 1373-1552 | Sentence | denotes | Using similar methods, a catalytic domain probe from Fuc-TIV identifies a new class of DNA fragments which do not cross-hybridize with the chromosome 19 fucosyltransferase probes. |
| T10 | 1553-1723 | Sentence | denotes | These results extend the molecular definition of a family of human alpha (1,3)fucosyltransferase genes and provide tools for examining fucosyltransferase gene expression. |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 1145-1155 | Body_part | denotes | chromosome | FMA:67093 |
| T2 | 1512-1522 | Body_part | denotes | chromosome | FMA:67093 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 42-47 | OrganismTaxon | denotes | human | 9606 |
| T2 | 281-286 | OrganismTaxon | denotes | human | 9606 |
| T3 | 464-469 | OrganismTaxon | denotes | human | 9606 |
| T4 | 1186-1191 | OrganismTaxon | denotes | human | 9606 |
| T5 | 1614-1619 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1145-1155 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |
| T2 | 1512-1522 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |