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GlyCosmos6-Glycan-Motif-Image

Id	Subject	Object	Predicate	Lexical cue	image
T1	162-177	Glycan_Motif	denotes	keratan sulfate	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82109MW
T2	179-181	Glycan_Motif	denotes	KS	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82109MW

Glycosmos6-GlycoEpitope

Id	Subject	Object	Predicate	Lexical cue
T1	162-177	http://www.glycoepitope.jp/epitopes/EP0085	denotes	keratan sulfate
T2	179-181	http://www.glycoepitope.jp/epitopes/EP0085	denotes	KS

sentences

Id	Subject	Object	Predicate	Lexical cue
TextSentencer_T1	0-55	Sentence	denotes	Roles of lumican and keratocan on corneal transparency.
TextSentencer_T2	56-215	Sentence	denotes	Lumican and keratocan are members of the small leucine-rich proteoglycan (SLRP) family, and are the major keratan sulfate (KS) proteoglycans in corneal stroma.
TextSentencer_T3	216-366	Sentence	denotes	Both lumican and keratocan are essential for normal cornea morphogenesis during embryonic development and maintenance of corneal topography in adults.
TextSentencer_T4	367-680	Sentence	denotes	This is attributed to their bi-functional characteristic (protein moiety binding collagen fibrils to regulate collagen fibril diameters, and highly charged glycosaminoglycan (GAG) chains extending out to regulate interfibrillar spacings) that contributes to their regulatory role in extracellular matrix assembly.
TextSentencer_T5	681-876	Sentence	denotes	The absence of lumican leads to formation of cloudy corneas in homozygous knockout mice due to altered collagenous matrix characterized by larger fibril diameters and disorganized fibril spacing.
TextSentencer_T6	877-1005	Sentence	denotes	In contrast, keratocan knockout mice exhibit thin but clear cornea with insignificant alteration of stromal collaegenous matrix.
TextSentencer_T7	1006-1098	Sentence	denotes	Mutations of keratocan cause cornea plana in human, which is often associated with glaucoma.
TextSentencer_T8	1099-1230	Sentence	denotes	These observations suggest that lumican and keratocan have different roles in regulating formation of stromal extracellular matrix.
TextSentencer_T9	1231-1471	Sentence	denotes	Experimental evidence indicates that lumican may have additional biological functions, such as modulation of cell migration and epithelium-mesenchyme transition in wound healing and tumorgenesis, besides regulating collagen fibrillogenesis.
T1	0-55	Sentence	denotes	Roles of lumican and keratocan on corneal transparency.
T2	56-215	Sentence	denotes	Lumican and keratocan are members of the small leucine-rich proteoglycan (SLRP) family, and are the major keratan sulfate (KS) proteoglycans in corneal stroma.
T3	216-366	Sentence	denotes	Both lumican and keratocan are essential for normal cornea morphogenesis during embryonic development and maintenance of corneal topography in adults.
T4	367-680	Sentence	denotes	This is attributed to their bi-functional characteristic (protein moiety binding collagen fibrils to regulate collagen fibril diameters, and highly charged glycosaminoglycan (GAG) chains extending out to regulate interfibrillar spacings) that contributes to their regulatory role in extracellular matrix assembly.
T5	681-876	Sentence	denotes	The absence of lumican leads to formation of cloudy corneas in homozygous knockout mice due to altered collagenous matrix characterized by larger fibril diameters and disorganized fibril spacing.
T6	877-1005	Sentence	denotes	In contrast, keratocan knockout mice exhibit thin but clear cornea with insignificant alteration of stromal collaegenous matrix.
T7	1006-1098	Sentence	denotes	Mutations of keratocan cause cornea plana in human, which is often associated with glaucoma.
T8	1099-1230	Sentence	denotes	These observations suggest that lumican and keratocan have different roles in regulating formation of stromal extracellular matrix.
T9	1231-1471	Sentence	denotes	Experimental evidence indicates that lumican may have additional biological functions, such as modulation of cell migration and epithelium-mesenchyme transition in wound healing and tumorgenesis, besides regulating collagen fibrillogenesis.

GlyCosmos6-Glycan-Motif-Structure

Id	Subject	Object	Predicate	Lexical cue
T1	162-177	https://glytoucan.org/Structures/Glycans/G82109MW	denotes	keratan sulfate

PubmedHPO

Id	Subject	Object	Predicate	Lexical cue
T1	726-740	HP_0007759	denotes	cloudy corneas
T2	922-943	HP_0100689	denotes	thin but clear cornea
T3	1035-1047	HP_0007720	denotes	cornea plana
T4	1089-1097	HP_0000501	denotes	glaucoma

DisGeNET5_gene_disease

Id	Subject	Object	Predicate	Lexical cue
12975606-6#13#22#gene11081	1019-1028	gene11081	denotes	keratocan
12975606-6#29#41#diseaseC0344529	1035-1047	diseaseC0344529	denotes	cornea plana
13#22#gene1108129#41#diseaseC0344529	12975606-6#13#22#gene11081	12975606-6#29#41#diseaseC0344529	associated_with	keratocan,cornea plana

DisGeNET

Id	Subject	Object	Predicate	Lexical cue
T0	1019-1028	gene:11081	denotes	keratocan
T1	1035-1047	disease:C0344529	denotes	cornea plana
T2	1019-1028	gene:11081	denotes	keratocan
T3	1089-1097	disease:C0017601	denotes	glaucoma
R1	T0	T1	associated_with	keratocan,cornea plana
R2	T2	T3	associated_with	keratocan,glaucoma

HP-phenotype

Id	Subject	Object	Predicate	Lexical cue	hp_id
T1	726-740	Phenotype	denotes	cloudy corneas	HP:0007759
T2	1035-1047	Phenotype	denotes	cornea plana	HP:0007720
T3	1089-1097	Phenotype	denotes	glaucoma	HP:0000501

mondo_disease

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T1	1035-1047	Disease	denotes	cornea plana	http://purl.obolibrary.org/obo/MONDO_0000733
T2	1089-1097	Disease	denotes	glaucoma	http://purl.obolibrary.org/obo/MONDO_0005041
T3	1395-1400	Disease	denotes	wound	http://purl.obolibrary.org/obo/MONDO_0021178

Glycan-GlyCosmos

Id	Subject	Object	Predicate	Lexical cue	image
T1	162-177	Glycan	denotes	keratan sulfate	https://api.glycosmos.org/wurcs2image/latest/png/binary/G82109MW
T2	179-181	Glycan	denotes	KS	https://api.glycosmos.org/wurcs2image/latest/png/binary/G82109MW

GlyCosmos-GlycoEpitope

Id	Subject	Object	Predicate	Lexical cue	glycoepitope_id
T1	162-177	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	keratan sulfate	http://www.glycoepitope.jp/epitopes/EP0085
T2	179-181	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	KS	http://www.glycoepitope.jp/epitopes/EP0085

GlyCosmos15-HP

Id	Subject	Object	Predicate	Lexical cue	hp_id
T1	726-740	Phenotype	denotes	cloudy corneas	HP:0007759
T2	1035-1047	Phenotype	denotes	cornea plana	HP:0007720
T3	1089-1097	Phenotype	denotes	glaucoma	HP:0000501

GlyCosmos15-MONDO

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T1	1035-1047	Disease	denotes	cornea plana	http://purl.obolibrary.org/obo/MONDO_0000733
T2	1089-1097	Disease	denotes	glaucoma	http://purl.obolibrary.org/obo/MONDO_0005041
T3	1395-1400	Disease	denotes	wound	http://purl.obolibrary.org/obo/MONDO_0021178

GlyCosmos15-NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	764-768	OrganismTaxon	denotes	mice	10088
T2	909-913	OrganismTaxon	denotes	mice	10088
T3	1051-1056	OrganismTaxon	denotes	human	9606
T4	1089-1097	OrganismTaxon	denotes	glaucoma	5882

GlyCosmos15-UBERON

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	200-214	Body_part	denotes	corneal stroma	http://purl.obolibrary.org/obo/UBERON_0001777
T2	268-274	Body_part	denotes	cornea	http://purl.obolibrary.org/obo/UBERON_0000964
T3	486-492	Body_part	denotes	fibril	http://purl.obolibrary.org/obo/GO_0099512
T4	650-670	Body_part	denotes	extracellular matrix	http://purl.obolibrary.org/obo/GO_0031012
T5	733-740	Body_part	denotes	corneas	http://purl.obolibrary.org/obo/UBERON_0000964
T6	827-833	Body_part	denotes	fibril	http://purl.obolibrary.org/obo/GO_0099512
T7	861-867	Body_part	denotes	fibril	http://purl.obolibrary.org/obo/GO_0099512
T8	937-943	Body_part	denotes	cornea	http://purl.obolibrary.org/obo/UBERON_0000964
T9	1035-1041	Body_part	denotes	cornea	http://purl.obolibrary.org/obo/UBERON_0000964
T10	1209-1229	Body_part	denotes	extracellular matrix	http://purl.obolibrary.org/obo/GO_0031012
T11	1345-1369	Body_part	denotes	migration and epithelium	http://purl.obolibrary.org/obo/UBERON_0007573
T12	1370-1380	Body_part	denotes	mesenchyme	http://purl.obolibrary.org/obo/UBERON_0003104

sentences

Id	Subject	Object	Predicate	Lexical cue
TextSentencer_T1	0-55	Sentence	denotes	Roles of lumican and keratocan on corneal transparency.
TextSentencer_T2	56-215	Sentence	denotes	Lumican and keratocan are members of the small leucine-rich proteoglycan (SLRP) family, and are the major keratan sulfate (KS) proteoglycans in corneal stroma.
TextSentencer_T3	216-366	Sentence	denotes	Both lumican and keratocan are essential for normal cornea morphogenesis during embryonic development and maintenance of corneal topography in adults.
TextSentencer_T4	367-680	Sentence	denotes	This is attributed to their bi-functional characteristic (protein moiety binding collagen fibrils to regulate collagen fibril diameters, and highly charged glycosaminoglycan (GAG) chains extending out to regulate interfibrillar spacings) that contributes to their regulatory role in extracellular matrix assembly.
TextSentencer_T5	681-876	Sentence	denotes	The absence of lumican leads to formation of cloudy corneas in homozygous knockout mice due to altered collagenous matrix characterized by larger fibril diameters and disorganized fibril spacing.
TextSentencer_T6	877-1005	Sentence	denotes	In contrast, keratocan knockout mice exhibit thin but clear cornea with insignificant alteration of stromal collaegenous matrix.
TextSentencer_T7	1006-1098	Sentence	denotes	Mutations of keratocan cause cornea plana in human, which is often associated with glaucoma.
TextSentencer_T8	1099-1230	Sentence	denotes	These observations suggest that lumican and keratocan have different roles in regulating formation of stromal extracellular matrix.
TextSentencer_T9	1231-1471	Sentence	denotes	Experimental evidence indicates that lumican may have additional biological functions, such as modulation of cell migration and epithelium-mesenchyme transition in wound healing and tumorgenesis, besides regulating collagen fibrillogenesis.
T1	0-55	Sentence	denotes	Roles of lumican and keratocan on corneal transparency.
T2	56-215	Sentence	denotes	Lumican and keratocan are members of the small leucine-rich proteoglycan (SLRP) family, and are the major keratan sulfate (KS) proteoglycans in corneal stroma.
T3	216-366	Sentence	denotes	Both lumican and keratocan are essential for normal cornea morphogenesis during embryonic development and maintenance of corneal topography in adults.
T4	367-680	Sentence	denotes	This is attributed to their bi-functional characteristic (protein moiety binding collagen fibrils to regulate collagen fibril diameters, and highly charged glycosaminoglycan (GAG) chains extending out to regulate interfibrillar spacings) that contributes to their regulatory role in extracellular matrix assembly.
T5	681-876	Sentence	denotes	The absence of lumican leads to formation of cloudy corneas in homozygous knockout mice due to altered collagenous matrix characterized by larger fibril diameters and disorganized fibril spacing.
T6	877-1005	Sentence	denotes	In contrast, keratocan knockout mice exhibit thin but clear cornea with insignificant alteration of stromal collaegenous matrix.
T7	1006-1098	Sentence	denotes	Mutations of keratocan cause cornea plana in human, which is often associated with glaucoma.
T8	1099-1230	Sentence	denotes	These observations suggest that lumican and keratocan have different roles in regulating formation of stromal extracellular matrix.
T9	1231-1471	Sentence	denotes	Experimental evidence indicates that lumican may have additional biological functions, such as modulation of cell migration and epithelium-mesenchyme transition in wound healing and tumorgenesis, besides regulating collagen fibrillogenesis.

GlyCosmos15-Sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-55	Sentence	denotes	Roles of lumican and keratocan on corneal transparency.
T2	56-215	Sentence	denotes	Lumican and keratocan are members of the small leucine-rich proteoglycan (SLRP) family, and are the major keratan sulfate (KS) proteoglycans in corneal stroma.
T3	216-366	Sentence	denotes	Both lumican and keratocan are essential for normal cornea morphogenesis during embryonic development and maintenance of corneal topography in adults.
T4	367-680	Sentence	denotes	This is attributed to their bi-functional characteristic (protein moiety binding collagen fibrils to regulate collagen fibril diameters, and highly charged glycosaminoglycan (GAG) chains extending out to regulate interfibrillar spacings) that contributes to their regulatory role in extracellular matrix assembly.
T5	681-876	Sentence	denotes	The absence of lumican leads to formation of cloudy corneas in homozygous knockout mice due to altered collagenous matrix characterized by larger fibril diameters and disorganized fibril spacing.
T6	877-1005	Sentence	denotes	In contrast, keratocan knockout mice exhibit thin but clear cornea with insignificant alteration of stromal collaegenous matrix.
T7	1006-1098	Sentence	denotes	Mutations of keratocan cause cornea plana in human, which is often associated with glaucoma.
T8	1099-1230	Sentence	denotes	These observations suggest that lumican and keratocan have different roles in regulating formation of stromal extracellular matrix.
T9	1231-1471	Sentence	denotes	Experimental evidence indicates that lumican may have additional biological functions, such as modulation of cell migration and epithelium-mesenchyme transition in wound healing and tumorgenesis, besides regulating collagen fibrillogenesis.

GlyCosmos15-Glycan

Id	Subject	Object	Predicate	Lexical cue	image
T1	162-177	Glycan	denotes	keratan sulfate	https://api.glycosmos.org/wurcs2image/latest/png/binary/G82109MW
T2	179-181	Glycan	denotes	KS	https://api.glycosmos.org/wurcs2image/latest/png/binary/G82109MW

GlyCosmos15-GlycoEpitope

Id	Subject	Object	Predicate	Lexical cue	glycoepitope_id
T1	162-177	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	keratan sulfate	http://www.glycoepitope.jp/epitopes/EP0085
T2	179-181	http://purl.jp/bio/12/glyco/glycan#Glycan_epitope	denotes	KS	http://www.glycoepitope.jp/epitopes/EP0085

NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	764-768	OrganismTaxon	denotes	mice	10088
T2	909-913	OrganismTaxon	denotes	mice	10088
T3	1051-1056	OrganismTaxon	denotes	human	9606
T4	1089-1097	OrganismTaxon	denotes	glaucoma	5882

Anatomy-UBERON

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	200-214	Body_part	denotes	corneal stroma	http://purl.obolibrary.org/obo/UBERON_0001777
T2	268-274	Body_part	denotes	cornea	http://purl.obolibrary.org/obo/UBERON_0000964
T3	486-492	Body_part	denotes	fibril	http://purl.obolibrary.org/obo/GO_0099512
T4	650-670	Body_part	denotes	extracellular matrix	http://purl.obolibrary.org/obo/GO_0031012
T5	733-740	Body_part	denotes	corneas	http://purl.obolibrary.org/obo/UBERON_0000964
T6	827-833	Body_part	denotes	fibril	http://purl.obolibrary.org/obo/GO_0099512
T7	861-867	Body_part	denotes	fibril	http://purl.obolibrary.org/obo/GO_0099512
T8	937-943	Body_part	denotes	cornea	http://purl.obolibrary.org/obo/UBERON_0000964
T9	1035-1041	Body_part	denotes	cornea	http://purl.obolibrary.org/obo/UBERON_0000964
T10	1209-1229	Body_part	denotes	extracellular matrix	http://purl.obolibrary.org/obo/GO_0031012
T11	1345-1369	Body_part	denotes	migration and epithelium	http://purl.obolibrary.org/obo/UBERON_0007573
T12	1370-1380	Body_part	denotes	mesenchyme	http://purl.obolibrary.org/obo/UBERON_0003104