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PubMed:12379519 / 0-1011 JSONTXT

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DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
12379519-2#143#148#gene4312 479-484 gene4312 denotes MMP 1
12379519-2#161#172#gene1513 497-508 gene1513 denotes cathepsin-K
12379519-2#236#242#gene7077 572-578 gene7077 denotes TIMP-2
12379519-2#100#109#diseaseC0003864 436-445 diseaseC0003864 denotes arthritis
143#148#gene4312100#109#diseaseC0003864 12379519-2#143#148#gene4312 12379519-2#100#109#diseaseC0003864 associated_with MMP 1,arthritis
161#172#gene1513100#109#diseaseC0003864 12379519-2#161#172#gene1513 12379519-2#100#109#diseaseC0003864 associated_with cathepsin-K,arthritis
236#242#gene7077100#109#diseaseC0003864 12379519-2#236#242#gene7077 12379519-2#100#109#diseaseC0003864 associated_with TIMP-2,arthritis

PubMed_Structured_Abstracts

Id Subject Object Predicate Lexical cue
T1 149-324 BACKGROUND denotes Matrix metalloproteinases (MMPs) have a pivotal role in the destruction of cartilage in rheumatoid arthritis (RA), which is mediated by the fibroblast-like synoviocytes (FLS).
T2 336-586 OBJECTIVE denotes To examine the in vitro invasiveness of synoviocytes obtained from inflamed joints of patients with arthritis in relation to the expression of MMP 1-14, 17, 19, cathepsin-K, the tissue inhibitors of matrix metalloproteinases TIMP-1 and TIMP-2 by FLS.