PubMed:12122022
Annnotations
Glycan-Motif
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1044-1051 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1044-1051 | Glycan_Motif | denotes | mannose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-182 | Sentence | denotes | Molecular analysis of a novel family of complex glycoinositolphosphoryl ceramides from Cryptococcus neoformans: structural differences between encapsulated and acapsular yeast forms. |
| TextSentencer_T2 | 183-385 | Sentence | denotes | Complex glycoinositolphosphoryl ceramides (GIPCs) have been purified from a pathogenic encapsulated wild-type (WT) strain of Cryptococcus neoformans var. neoformans and from an acapsular mutant (Cap67). |
| TextSentencer_T3 | 386-602 | Sentence | denotes | The structures of the GIPCs were determined by a combination of tandem mass spectrometry, nuclear magnetic resonance spectroscopy, methylation analysis, gas chromatography-mass spectrometry, and chemical degradation. |
| TextSentencer_T4 | 603-1097 | Sentence | denotes | The main GIPC from the WT strain had the structure Manp(alpha1-3)[Xylp(beta1-2)] Manp(alpha1-4)Galp(beta1-6)Manp(alpha1-2)Ins-1-phosphoryl ceramide (GIPC A), whereas the compounds from the acapsular mutant were more heterogeneous in their glycan chains, and variants with Manp(alpha1-6) (GIPC B), Manp(alpha1-6) Manp(alpha1-6) (GIPC C), and Manp(alpha1-2)Manp(alpha1-6)Manp(alpha1-6) (GIPC D) substituents linked to the nonreducing terminal mannose residue found in the WT GIPC A were abundant. |
| TextSentencer_T5 | 1098-1415 | Sentence | denotes | The ceramide moieties of C. neoformans GIPCs were composed of a C(18) phytosphingosine long-chain base mainly N-acylated with 2-hydroxy-tetracosanoic acid in the WT GIPC while in the acapsular Cap67 mutant GIPCs, as well as 2-hydroxy-tetracosanoic acid, the unusual 2,3-dihydroxy-tetracosanoic acid was characterized. |
| TextSentencer_T6 | 1416-1548 | Sentence | denotes | In addition, structural analysis revealed that the amount of GIPC in the WT cells was fourfold less of that in the acapsular mutant. |
| T1 | 0-182 | Sentence | denotes | Molecular analysis of a novel family of complex glycoinositolphosphoryl ceramides from Cryptococcus neoformans: structural differences between encapsulated and acapsular yeast forms. |
| T2 | 183-385 | Sentence | denotes | Complex glycoinositolphosphoryl ceramides (GIPCs) have been purified from a pathogenic encapsulated wild-type (WT) strain of Cryptococcus neoformans var. neoformans and from an acapsular mutant (Cap67). |
| T3 | 386-602 | Sentence | denotes | The structures of the GIPCs were determined by a combination of tandem mass spectrometry, nuclear magnetic resonance spectroscopy, methylation analysis, gas chromatography-mass spectrometry, and chemical degradation. |
| T4 | 603-1097 | Sentence | denotes | The main GIPC from the WT strain had the structure Manp(alpha1-3)[Xylp(beta1-2)] Manp(alpha1-4)Galp(beta1-6)Manp(alpha1-2)Ins-1-phosphoryl ceramide (GIPC A), whereas the compounds from the acapsular mutant were more heterogeneous in their glycan chains, and variants with Manp(alpha1-6) (GIPC B), Manp(alpha1-6) Manp(alpha1-6) (GIPC C), and Manp(alpha1-2)Manp(alpha1-6)Manp(alpha1-6) (GIPC D) substituents linked to the nonreducing terminal mannose residue found in the WT GIPC A were abundant. |
| T5 | 1098-1415 | Sentence | denotes | The ceramide moieties of C. neoformans GIPCs were composed of a C(18) phytosphingosine long-chain base mainly N-acylated with 2-hydroxy-tetracosanoic acid in the WT GIPC while in the acapsular Cap67 mutant GIPCs, as well as 2-hydroxy-tetracosanoic acid, the unusual 2,3-dihydroxy-tetracosanoic acid was characterized. |
| T6 | 1416-1548 | Sentence | denotes | In addition, structural analysis revealed that the amount of GIPC in the WT cells was fourfold less of that in the acapsular mutant. |
| T1 | 0-182 | Sentence | denotes | Molecular analysis of a novel family of complex glycoinositolphosphoryl ceramides from Cryptococcus neoformans: structural differences between encapsulated and acapsular yeast forms. |
| T2 | 183-385 | Sentence | denotes | Complex glycoinositolphosphoryl ceramides (GIPCs) have been purified from a pathogenic encapsulated wild-type (WT) strain of Cryptococcus neoformans var. neoformans and from an acapsular mutant (Cap67). |
| T3 | 386-602 | Sentence | denotes | The structures of the GIPCs were determined by a combination of tandem mass spectrometry, nuclear magnetic resonance spectroscopy, methylation analysis, gas chromatography-mass spectrometry, and chemical degradation. |
| T4 | 603-1097 | Sentence | denotes | The main GIPC from the WT strain had the structure Manp(alpha1-3)[Xylp(beta1-2)] Manp(alpha1-4)Galp(beta1-6)Manp(alpha1-2)Ins-1-phosphoryl ceramide (GIPC A), whereas the compounds from the acapsular mutant were more heterogeneous in their glycan chains, and variants with Manp(alpha1-6) (GIPC B), Manp(alpha1-6) Manp(alpha1-6) (GIPC C), and Manp(alpha1-2)Manp(alpha1-6)Manp(alpha1-6) (GIPC D) substituents linked to the nonreducing terminal mannose residue found in the WT GIPC A were abundant. |
| T5 | 1098-1415 | Sentence | denotes | The ceramide moieties of C. neoformans GIPCs were composed of a C(18) phytosphingosine long-chain base mainly N-acylated with 2-hydroxy-tetracosanoic acid in the WT GIPC while in the acapsular Cap67 mutant GIPCs, as well as 2-hydroxy-tetracosanoic acid, the unusual 2,3-dihydroxy-tetracosanoic acid was characterized. |
| T6 | 1416-1548 | Sentence | denotes | In addition, structural analysis revealed that the amount of GIPC in the WT cells was fourfold less of that in the acapsular mutant. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1044-1051 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
GlycoBiology-PACDB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 87-110 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC642 | denotes | Cryptococcus neoformans |
| _T2 | 87-110 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC759 | denotes | Cryptococcus neoformans |
| _T3 | 87-110 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC597 | denotes | Cryptococcus neoformans |
| _T4 | 308-331 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC642 | denotes | Cryptococcus neoformans |
| _T5 | 308-331 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC759 | denotes | Cryptococcus neoformans |
| _T6 | 308-331 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC597 | denotes | Cryptococcus neoformans |
| _T7 | 308-347 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC074 | denotes | Cryptococcus neoformans var. neoformans |
| _T8 | 308-347 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC067 | denotes | Cryptococcus neoformans var. neoformans |
| _T9 | 308-347 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC753 | denotes | Cryptococcus neoformans var. neoformans |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 539-542 | FMAID:85816 | denotes | gas |
| _T2 | 607-611 | FMAID:214734 | denotes | main |
| _T3 | 773-782 | FMAID:67745 | denotes | compounds |
| _T4 | 773-782 | FMAID:165656 | denotes | compounds |
| _T5 | 1044-1051 | FMAID:82801 | denotes | mannose |
| _T6 | 1044-1051 | FMAID:196796 | denotes | mannose |
| _T7 | 1492-1497 | FMAID:68646 | denotes | cells |
| _T8 | 1492-1497 | FMAID:169002 | denotes | cells |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 612-616 | http://www.uniprot.org/uniprot/O14908 | denotes | GIPC |
| T2 | 752-756 | http://www.uniprot.org/uniprot/O14908 | denotes | GIPC |
| T3 | 891-895 | http://www.uniprot.org/uniprot/O14908 | denotes | GIPC |
| T4 | 931-935 | http://www.uniprot.org/uniprot/O14908 | denotes | GIPC |
| T5 | 988-992 | http://www.uniprot.org/uniprot/O14908 | denotes | GIPC |
| T6 | 1076-1080 | http://www.uniprot.org/uniprot/O14908 | denotes | GIPC |
| T7 | 1263-1267 | http://www.uniprot.org/uniprot/O14908 | denotes | GIPC |
| T8 | 1477-1481 | http://www.uniprot.org/uniprot/O14908 | denotes | GIPC |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 332-335 | http://www.uniprot.org/uniprot/Q9Z1Q9 | denotes | var |
| T2 | 654-658 | http://www.uniprot.org/uniprot/Q00PI9 | denotes | Manp |
| T3 | 684-688 | http://www.uniprot.org/uniprot/Q00PI9 | denotes | Manp |
| T4 | 711-715 | http://www.uniprot.org/uniprot/Q00PI9 | denotes | Manp |
| T5 | 875-879 | http://www.uniprot.org/uniprot/Q00PI9 | denotes | Manp |
| T6 | 900-904 | http://www.uniprot.org/uniprot/Q00PI9 | denotes | Manp |
| T7 | 915-919 | http://www.uniprot.org/uniprot/Q00PI9 | denotes | Manp |
| T8 | 944-948 | http://www.uniprot.org/uniprot/Q00PI9 | denotes | Manp |
| T9 | 958-962 | http://www.uniprot.org/uniprot/Q00PI9 | denotes | Manp |
| T10 | 972-976 | http://www.uniprot.org/uniprot/Q00PI9 | denotes | Manp |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 87-99 | http://purl.bioontology.org/ontology/NCBITAXON/89915 | denotes | Cryptococcus |
| T2 | 87-99 | http://purl.bioontology.org/ontology/NCBITAXON/107441 | denotes | Cryptococcus |
| T3 | 87-99 | http://purl.bioontology.org/ontology/NCBITAXON/106841 | denotes | Cryptococcus |
| T4 | 87-99 | http://purl.bioontology.org/ontology/NCBITAXON/561281 | denotes | Cryptococcus |
| T5 | 87-99 | http://purl.bioontology.org/ontology/NCBITAXON/104409 | denotes | Cryptococcus |
| T6 | 87-99 | http://purl.bioontology.org/ontology/NCBITAXON/214992 | denotes | Cryptococcus |
| T7 | 308-320 | http://purl.bioontology.org/ontology/NCBITAXON/561281 | denotes | Cryptococcus |
| T8 | 308-320 | http://purl.bioontology.org/ontology/NCBITAXON/104409 | denotes | Cryptococcus |
| T9 | 308-320 | http://purl.bioontology.org/ontology/NCBITAXON/89915 | denotes | Cryptococcus |
| T10 | 308-320 | http://purl.bioontology.org/ontology/NCBITAXON/106841 | denotes | Cryptococcus |
| T11 | 308-320 | http://purl.bioontology.org/ontology/NCBITAXON/107441 | denotes | Cryptococcus |
| T12 | 308-320 | http://purl.bioontology.org/ontology/NCBITAXON/214992 | denotes | Cryptococcus |
| T13 | 819-832 | http://purl.bioontology.org/ontology/NCBITAXON/1113441 | denotes | heterogeneous |
| T14 | 819-832 | http://purl.bioontology.org/ontology/NCBITAXON/691256 | denotes | heterogeneous |
| T15 | 1492-1497 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 517-528 | http://purl.obolibrary.org/obo/GO_0032259 | denotes | methylation |
| T2 | 539-542 | http://purl.obolibrary.org/obo/GO_0034005 | denotes | gas |
| T3 | 590-601 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | degradation |
| T4 | 731-741 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphoryl |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1492-1497 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 170-175 | http://edamontology.org/topic_2817 | denotes | yeast |
| T2 | 170-175 | http://edamontology.org/topic_0782 | denotes | yeast |
| T3 | 259-269 | http://edamontology.org/topic_0783 | denotes | pathogenic |
| T4 | 457-474 | http://edamontology.org/topic_0134 | denotes | mass spectrometry |
| T5 | 457-474 | http://edamontology.org/topic_3520 | denotes | mass spectrometry |
| T6 | 476-502 | http://edamontology.org/topic_3444 | denotes | nuclear magnetic resonance |
| T7 | 476-515 | http://edamontology.org/topic_0593 | denotes | nuclear magnetic resonance spectroscopy |
| T8 | 503-515 | http://edamontology.org/topic_0593 | denotes | spectroscopy |
| T9 | 558-575 | http://edamontology.org/topic_0134 | denotes | mass spectrometry |
| T10 | 558-575 | http://edamontology.org/topic_3520 | denotes | mass spectrometry |
| T11 | 1035-1043 | http://edamontology.org/topic_0749 | denotes | terminal |
| T12 | 1429-1448 | http://edamontology.org/topic_0081 | denotes | structural analysis |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-18 | http://edamontology.org/operation_2948 | denotes | Molecular analysis |
| T2 | 0-18 | http://edamontology.org/operation_3351 | denotes | Molecular analysis |
| T3 | 10-18 | http://edamontology.org/operation_2945 | denotes | analysis |
| T4 | 112-122 | http://edamontology.org/data_0883 | denotes | structural |
| T5 | 259-269 | http://edamontology.org/data_3718 | denotes | pathogenic |
| T6 | 390-400 | http://edamontology.org/data_0883 | denotes | structures |
| T7 | 457-474 | http://edamontology.org/data_2536 | denotes | mass spectrometry |
| T8 | 457-474 | http://edamontology.org/data_3147 | denotes | mass spectrometry |
| T9 | 517-537 | http://edamontology.org/operation_3204 | denotes | methylation analysis |
| T10 | 529-537 | http://edamontology.org/operation_2945 | denotes | analysis |
| T11 | 558-575 | http://edamontology.org/data_3147 | denotes | mass spectrometry |
| T12 | 558-575 | http://edamontology.org/data_2536 | denotes | mass spectrometry |
| T13 | 644-653 | http://edamontology.org/data_0883 | denotes | structure |
| T14 | 1052-1059 | http://edamontology.org/data_1756 | denotes | residue |
| T15 | 1429-1439 | http://edamontology.org/data_0883 | denotes | structural |
| T16 | 1429-1448 | http://edamontology.org/operation_2480 | denotes | structural analysis |
| T17 | 1440-1448 | http://edamontology.org/operation_2945 | denotes | analysis |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 87-110 | OrganismTaxon | denotes | Cryptococcus neoformans | 5207 |
| T2 | 308-347 | OrganismTaxon | denotes | Cryptococcus neoformans var. neoformans | 40410 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 170-181 | Cell | denotes | yeast forms | http://purl.obolibrary.org/obo/CL:0000334 |