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PubMed:11719522 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-169 Sentence denotes Molecular cloning and characterization of the human diacylglycerol kinase beta (DGKbeta) gene: alternative splicing generates DGKbeta isotypes with different properties.
T2 170-329 Sentence denotes Diacylglycerol kinases are key modulators of levels of diacylglycerol, a second messenger involved in a variety of cellular responses to extracellular stimuli.
T3 330-424 Sentence denotes A number of diacylglycerol kinases encoded by separate genes are present in mammalian genomes.
T4 425-693 Sentence denotes We have cloned cDNAs encoding several isoforms of the human homologue of the rat diacylglycerol kinase beta gene and characterized two such isoforms that differ at their carboxyl terminus through alternative splicing and the usage of different polyadenylation signals.
T5 694-956 Sentence denotes Quantitative analysis of gene expression in a panel of human tissue cDNAs revealed that transcripts corresponding to both isoforms are co-expressed in central nervous system tissues and in the uterus, with one variant being expressed at relatively higher levels.
T6 957-1207 Sentence denotes As green fluorescent protein fusions, the two isoforms displayed localization to different subcellular compartments, with one variant being associated with the plasma membrane, while the other isoform was predominantly localized within the cytoplasm.
T7 1208-1314 Sentence denotes Differences were also observed in their subcellular localization in response to phorbol ester stimulation.
T8 1315-1419 Sentence denotes Enzymatic assays demonstrated that the two isoforms display comparable diacylglycerol kinase activities.
T9 1420-1628 Sentence denotes Therefore, the human diacylglycerol kinase beta gene can generate several enzyme isoforms, which can display different expression levels and subcellular localization but similar enzymatic activities in vitro.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 845-867 http://purl.obolibrary.org/obo/MAT_0000457 denotes central nervous system
T2 853-867 http://purl.obolibrary.org/obo/MAT_0000026 denotes nervous system
T3 887-893 http://purl.obolibrary.org/obo/MAT_0000127 denotes uterus

FSU-PRGE

Id Subject Object Predicate Lexical cue
T1 52-78 protein denotes diacylglycerol kinase beta
T2 80-87 protein denotes DGKbeta
T3 126-133 protein denotes DGKbeta
T4 170-192 protein denotes Diacylglycerol kinases
T5 342-364 protein denotes diacylglycerol kinases
T6 506-532 protein denotes diacylglycerol kinase beta
T7 960-985 protein denotes green fluorescent protein
T8 1386-1407 protein denotes diacylglycerol kinase
T9 1441-1467 protein denotes diacylglycerol kinase beta

PIR-corpus2

Id Subject Object Predicate Lexical cue
T1 52-73 protein denotes diacylglycerol kinase
T2 126-142 protein denotes DGKbeta isotypes
T3 170-192 protein denotes Diacylglycerol kinases
T4 342-364 protein denotes diacylglycerol kinases
T5 506-520 protein denotes diacylglycerol
T6 1386-1407 protein denotes diacylglycerol kinase
T7 1441-1467 protein denotes diacylglycerol kinase beta
T8 46-73 long_form denotes human diacylglycerol kinase
T12 502-520 long_form denotes rat diacylglycerol
T14 1435-1440 long_form denotes human

PIR-corpus1

Id Subject Object Predicate Lexical cue
T1 126-142 protein denotes DGKbeta isotypes
T2 170-192 protein denotes Diacylglycerol kinases
T3 342-364 protein denotes diacylglycerol kinases
T4 960-985 protein denotes green fluorescent protein
T5 1386-1407 protein denotes diacylglycerol kinase
T6 1494-1509 protein denotes enzyme isoforms

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 845-867 Body_part denotes central nervous system http://purl.obolibrary.org/obo/MAT_0000457
T2 887-893 Body_part denotes uterus http://purl.obolibrary.org/obo/MAT_0000127

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 46-51 OrganismTaxon denotes human 9606
T2 479-484 OrganismTaxon denotes human 9606
T3 502-505 OrganismTaxon denotes rat 10114|10116
T5 749-754 OrganismTaxon denotes human 9606
T6 1435-1440 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 307-320 Body_part denotes extracellular http://purl.obolibrary.org/obo/GO_0005576
T2 755-761 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T3 845-867 Body_part denotes central nervous system http://purl.obolibrary.org/obo/UBERON_0001017
T4 887-893 Body_part denotes uterus http://purl.obolibrary.org/obo/UBERON_0000995|http://purl.obolibrary.org/obo/UBERON_0006834
T6 1117-1132 Body_part denotes plasma membrane http://purl.obolibrary.org/obo/GO_0005886
T7 1197-1206 Body_part denotes cytoplasm http://purl.obolibrary.org/obo/GO_0005737