PubMed:11341997
Annnotations
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T5 | 1454-1467 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/MAT_0000303 |
| T1 | 91-96 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/MAT_0000035 |
| T2 | 372-380 | Body_part | denotes | arterial | http://purl.obolibrary.org/obo/MAT_0000034 |
| T3 | 860-873 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/MAT_0000303 |
| T4 | 886-899 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/MAT_0000303 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 54-77 | Phenotype | denotes | atherosclerotic lesions | HP:0031678 |
| T2 | 138-147 | Phenotype | denotes | foam cell | HP:0003651 |
| T3 | 446-469 | Phenotype | denotes | atherosclerotic lesions | HP:0031678 |
| T4 | 483-493 | Phenotype | denotes | foam cells | HP:0003651 |
| T5 | 622-632 | Phenotype | denotes | foam cells | HP:0003651 |
| T6 | 737-747 | Phenotype | denotes | foam cells | HP:0003651 |
| T7 | 1021-1031 | Phenotype | denotes | foam cells | HP:0003651 |
| T8 | 1077-1087 | Phenotype | denotes | foam cells | HP:0003651 |
| T9 | 1129-1139 | Phenotype | denotes | foam cells | HP:0003651 |
| T10 | 1333-1343 | Phenotype | denotes | foam cells | HP:0003651 |
| T11 | 1604-1614 | Phenotype | denotes | foam cells | HP:0003651 |
| T12 | 1711-1720 | Phenotype | denotes | foam cell | HP:0003651 |
| T13 | 1816-1826 | Phenotype | denotes | foam cells | HP:0003651 |
| T14 | 1852-1875 | Phenotype | denotes | atherosclerotic lesions | HP:0031678 |
| T15 | 2043-2066 | Phenotype | denotes | atherosclerotic lesions | HP:0031678 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 32-35 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T2 | 131-134 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T3 | 285-288 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T4 | 312-315 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T5 | 424-427 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T6 | 699-702 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T7 | 1102-1105 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T8 | 1551-1554 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T9 | 1649-1652 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T10 | 1907-1910 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T11 | 1969-1972 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 54-77 | Phenotype | denotes | atherosclerotic lesions | HP:0031678 |
| T2 | 138-147 | Phenotype | denotes | foam cell | HP:0003651 |
| T3 | 446-469 | Phenotype | denotes | atherosclerotic lesions | HP:0031678 |
| T4 | 483-493 | Phenotype | denotes | foam cells | HP:0003651 |
| T5 | 622-632 | Phenotype | denotes | foam cells | HP:0003651 |
| T6 | 737-747 | Phenotype | denotes | foam cells | HP:0003651 |
| T7 | 1021-1031 | Phenotype | denotes | foam cells | HP:0003651 |
| T8 | 1077-1087 | Phenotype | denotes | foam cells | HP:0003651 |
| T9 | 1129-1139 | Phenotype | denotes | foam cells | HP:0003651 |
| T10 | 1333-1343 | Phenotype | denotes | foam cells | HP:0003651 |
| T11 | 1604-1614 | Phenotype | denotes | foam cells | HP:0003651 |
| T12 | 1711-1720 | Phenotype | denotes | foam cell | HP:0003651 |
| T13 | 1816-1826 | Phenotype | denotes | foam cells | HP:0003651 |
| T14 | 1852-1875 | Phenotype | denotes | atherosclerotic lesions | HP:0031678 |
| T15 | 2043-2066 | Phenotype | denotes | atherosclerotic lesions | HP:0031678 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 91-96 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/UBERON_0000947 |
| T2 | 372-387 | Body_part | denotes | arterial intima | http://purl.obolibrary.org/obo/UBERON_0005740 |
| T3 | 832-843 | Body_part | denotes | macrophages | http://purl.obolibrary.org/obo/CL_0000235 |
| T4 | 860-879 | Body_part | denotes | smooth muscle cells | http://purl.obolibrary.org/obo/CL_0000192 |
| T5 | 886-899 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/UBERON_0001135 |
| T6 | 1160-1168 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T9 | 1173-1185 | Body_part | denotes | myofilaments | http://purl.obolibrary.org/obo/GO_0036379 |
| T10 | 1228-1237 | Body_part | denotes | lysosomes | http://purl.obolibrary.org/obo/GO_0005764 |
| T11 | 1258-1280 | Body_part | denotes | morphological features | http://purl.obolibrary.org/obo/UBERON_0034768 |
| T12 | 1308-1318 | Body_part | denotes | macrophage | http://purl.obolibrary.org/obo/CL_0000235 |
| T13 | 1360-1372 | Body_part | denotes | myofilaments | http://purl.obolibrary.org/obo/GO_0036379 |
| T14 | 1396-1404 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T17 | 1431-1439 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T20 | 1454-1472 | Body_part | denotes | smooth muscle cell | http://purl.obolibrary.org/obo/CL_0000192 |
| T21 | 1762-1770 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T24 | 1893-1906 | Body_part | denotes | extracellular | http://purl.obolibrary.org/obo/GO_0005576 |
| T25 | 1943-1958 | Body_part | denotes | extracellularly | http://purl.obolibrary.org/obo/GO_0005576 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 85-90 | OrganismTaxon | denotes | human | 9606 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 138-147 | Cell | denotes | foam cell | http://purl.obolibrary.org/obo/CL:0000891 |
| T2 | 483-493 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T3 | 622-632 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T4 | 737-747 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T5 | 832-843 | Cell | denotes | macrophages | http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394 |
| T7 | 860-879 | Cell | denotes | smooth muscle cells | http://purl.obolibrary.org/obo/CL:0000192 |
| T8 | 1021-1031 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T9 | 1077-1087 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T10 | 1129-1139 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T11 | 1154-1159 | Cell | denotes | basal | http://purl.obolibrary.org/obo/CL:0002324 |
| T12 | 1308-1318 | Cell | denotes | macrophage | http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394 |
| T14 | 1333-1343 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T15 | 1390-1395 | Cell | denotes | basal | http://purl.obolibrary.org/obo/CL:0002324 |
| T16 | 1454-1472 | Cell | denotes | smooth muscle cell | http://purl.obolibrary.org/obo/CL:0000192 |
| T17 | 1461-1472 | Cell | denotes | muscle cell | http://purl.obolibrary.org/obo/CL:0000187 |
| T18 | 1604-1614 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T19 | 1711-1720 | Cell | denotes | foam cell | http://purl.obolibrary.org/obo/CL:0000891 |
| T20 | 1816-1826 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T5 | 1454-1467 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/MAT_0000303 |
| T1 | 91-96 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/MAT_0000035 |
| T2 | 372-380 | Body_part | denotes | arterial | http://purl.obolibrary.org/obo/MAT_0000034 |
| T3 | 860-873 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/MAT_0000303 |
| T4 | 886-899 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/MAT_0000303 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-97 | Sentence | denotes | Phenotype determination of anti-GM3 positive cells in atherosclerotic lesions of the human aorta. |
| T2 | 98-158 | Sentence | denotes | Hypothetical role of ganglioside GM3 in foam cell formation. |
| T3 | 159-388 | Sentence | denotes | Earlier we reported that atherosclerotic plaques contain cells which were specifically and very intensively stained with anti-GM3 antibodies although no GM3 positive cells were detected in the normal non-diseased arterial intima. |
| T4 | 389-532 | Sentence | denotes | Because of their lipid inclusions, GM3 positive cells in atherosclerotic lesions seemed to be foam cells but their origin needed clarification. |
| T5 | 533-656 | Sentence | denotes | Using an immunohistochemical technique in the present work, we showed that some of these foam cells contained CD68 antigen. |
| T6 | 657-1032 | Sentence | denotes | However, the most intense accumulation of GM3 occurred in the areas composed of foam cells which did not stain with any cell type-specific antibodies, including antibodies to macrophages (anti-CD68) and smooth muscle cells (anti-smooth muscle alpha-actin), perhaps, because the cell type-specific antigens were lost during the transformation of intimal cells into foam cells. |
| T7 | 1033-1326 | Sentence | denotes | Ultrastructural analysis of the areas where foam cells overexpressed GM3 demonstrated that some foam cells lacked both a basal membrane and myofilaments but contained a large number of secondary lysosomes and phagolysosomes, morphological features which might indicate their macrophage origin. |
| T8 | 1327-1480 | Sentence | denotes | Other foam cells contained a few myofilaments and fragments of basal membrane around their plasmalemmal membrane, suggesting a smooth muscle cell origin. |
| T9 | 1481-1615 | Sentence | denotes | These observations indicate that accumulation of excessive amounts of GM3 occurs in different cell types transforming into foam cells. |
| T10 | 1616-1731 | Sentence | denotes | We suggest that up-regulation of GM3 synthesis in intimal cells might be an essential event in foam cell formation. |
| T11 | 1732-1924 | Sentence | denotes | Shedding of a large number of membrane-bound microvesicles from the cell surface of foam cells was observed in areas of atherosclerotic lesions corresponding to extracellular GM3 accumulation. |
| T12 | 1925-2067 | Sentence | denotes | We speculate that extracellularly localised GM3 might affect the differentiation and modification of intimal cells in atherosclerotic lesions. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 32-35 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T2 | 131-134 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T3 | 285-288 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T4 | 312-315 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T5 | 424-427 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T6 | 699-702 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T7 | 1102-1105 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T8 | 1551-1554 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T9 | 1649-1652 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T10 | 1907-1910 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T11 | 1969-1972 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 85-90 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 91-96 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/UBERON_0000947 |
| T2 | 372-387 | Body_part | denotes | arterial intima | http://purl.obolibrary.org/obo/UBERON_0005740 |
| T3 | 832-843 | Body_part | denotes | macrophages | http://purl.obolibrary.org/obo/CL_0000235 |
| T4 | 860-879 | Body_part | denotes | smooth muscle cells | http://purl.obolibrary.org/obo/CL_0000192 |
| T5 | 886-899 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/UBERON_0001135 |
| T6 | 1160-1168 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T9 | 1173-1185 | Body_part | denotes | myofilaments | http://purl.obolibrary.org/obo/GO_0036379 |
| T10 | 1228-1237 | Body_part | denotes | lysosomes | http://purl.obolibrary.org/obo/GO_0005764 |
| T11 | 1258-1280 | Body_part | denotes | morphological features | http://purl.obolibrary.org/obo/UBERON_0034768 |
| T12 | 1308-1318 | Body_part | denotes | macrophage | http://purl.obolibrary.org/obo/CL_0000235 |
| T13 | 1360-1372 | Body_part | denotes | myofilaments | http://purl.obolibrary.org/obo/GO_0036379 |
| T14 | 1396-1404 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T17 | 1431-1439 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T20 | 1454-1472 | Body_part | denotes | smooth muscle cell | http://purl.obolibrary.org/obo/CL_0000192 |
| T21 | 1762-1770 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T24 | 1893-1906 | Body_part | denotes | extracellular | http://purl.obolibrary.org/obo/GO_0005576 |
| T25 | 1943-1958 | Body_part | denotes | extracellularly | http://purl.obolibrary.org/obo/GO_0005576 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 138-147 | Cell | denotes | foam cell | http://purl.obolibrary.org/obo/CL:0000891 |
| T2 | 483-493 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T3 | 622-632 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T4 | 737-747 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T5 | 832-843 | Cell | denotes | macrophages | http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394 |
| T7 | 860-879 | Cell | denotes | smooth muscle cells | http://purl.obolibrary.org/obo/CL:0000192 |
| T8 | 1021-1031 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T9 | 1077-1087 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T10 | 1129-1139 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T11 | 1154-1159 | Cell | denotes | basal | http://purl.obolibrary.org/obo/CL:0002324 |
| T12 | 1308-1318 | Cell | denotes | macrophage | http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394 |
| T14 | 1333-1343 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T15 | 1390-1395 | Cell | denotes | basal | http://purl.obolibrary.org/obo/CL:0002324 |
| T16 | 1454-1472 | Cell | denotes | smooth muscle cell | http://purl.obolibrary.org/obo/CL:0000192 |
| T17 | 1461-1472 | Cell | denotes | muscle cell | http://purl.obolibrary.org/obo/CL:0000187 |
| T18 | 1604-1614 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |
| T19 | 1711-1720 | Cell | denotes | foam cell | http://purl.obolibrary.org/obo/CL:0000891 |
| T20 | 1816-1826 | Cell | denotes | foam cells | http://purl.obolibrary.org/obo/CL:0000891 |