PubMed:10988255 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/10988255","sourcedb":"PubMed","sourceid":"10988255","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/10988255","text":"Phosphorylcholine-containing N-glycans of Trichinella spiralis: identification of multiantennary lacdiNAc structures.\nAlthough the presence of phosphorylcholine (PC) in Trichinella spiralis is well established, the precise structure of the PC-bearing molecules is not known. In this paper, we report structural studies of N-glycans released from T.spiralis affinity-purified antigens by peptide N-glycosidase F. Three classes of N-glycan structures were observed: high mannose type structures; those which had been fully trimmed to the trimannosyl core and were sub-stoichiometrically fucosylated; and those with a trimannosyl core, with and without core fucosylation, carrying between one and eight N-acetylhexosamine residues. Of the three classes of glycans, only the last was found to be substituted with detectable levels of 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