PubMed:10938272 / 813-1110 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/10938272","sourcedb":"PubMed","sourceid":"10938272","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/10938272","text":"Quinidine-treated MCF-7 cells showed elevated p21(WAF1), hypophosphorylation and suppression of retinoblastoma protein, and down-regulation of cyclin D1, similar to the cell cycle response observed with cells induced to differentiate by histone deacetylase inhibitors, trichostatin A, and trapoxin","tracks":[{"project":"PubmedHPO","denotations":[{"id":"T4","span":{"begin":96,"end":110},"obj":"HP_0009919"}],"attributes":[{"subj":"T4","pred":"source","obj":"PubmedHPO"}]},{"project":"bionlp-st-epi-2011-training","denotations":[{"id":"T5","span":{"begin":46,"end":49},"obj":"Protein"},{"id":"T6","span":{"begin":50,"end":54},"obj":"Protein"},{"id":"T7","span":{"begin":96,"end":110},"obj":"Protein"},{"id":"T8","span":{"begin":143,"end":152},"obj":"Protein"},{"id":"T9","span":{"begin":237,"end":244},"obj":"Protein"}],"attributes":[{"subj":"T5","pred":"source","obj":"bionlp-st-epi-2011-training"},{"subj":"T6","pred":"source","obj":"bionlp-st-epi-2011-training"},{"subj":"T7","pred":"source","obj":"bionlp-st-epi-2011-training"},{"subj":"T8","pred":"source","obj":"bionlp-st-epi-2011-training"},{"subj":"T9","pred":"source","obj":"bionlp-st-epi-2011-training"}]},{"project":"2015-BEL-Sample-2","denotations":[{"id":"BEL:20024938","span":{"begin":0,"end":297},"obj":"a(CHEBI:quinidine) decreases p(HGNC:CCND1)"},{"id":"BEL:20024940","span":{"begin":0,"end":297},"obj":"a(CHEBI:quinidine) increases p(HGNC:CDKN1A)"},{"id":"BEL:20024942","span":{"begin":0,"end":297},"obj":"a(CHEBI:quinidine) decreases p(HGNC:RB1)"},{"id":"BEL:20024944","span":{"begin":0,"end":297},"obj":"a(CHEBI:quinidine) decreases p(HGNC:RB1,pmod(P))"}],"attributes":[{"subj":"BEL:20024938","pred":"source","obj":"2015-BEL-Sample-2"},{"subj":"BEL:20024940","pred":"source","obj":"2015-BEL-Sample-2"},{"subj":"BEL:20024942","pred":"source","obj":"2015-BEL-Sample-2"},{"subj":"BEL:20024944","pred":"source","obj":"2015-BEL-Sample-2"}]},{"project":"HP-phenotype","denotations":[{"id":"T3","span":{"begin":96,"end":110},"obj":"Phenotype"}],"attributes":[{"id":"A3","pred":"hp_id","subj":"T3","obj":"HP:0009919"},{"subj":"T3","pred":"source","obj":"HP-phenotype"}],"namespaces":[{"prefix":"HP","uri":"http://purl.obolibrary.org/obo/HP_"}]},{"project":"mondo_disease","denotations":[{"id":"T5","span":{"begin":96,"end":110},"obj":"Disease"}],"attributes":[{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0008380"},{"subj":"T5","pred":"source","obj":"mondo_disease"}]},{"project":"Anatomy-UBERON","denotations":[{"id":"T6","span":{"begin":169,"end":179},"obj":"Body_part"}],"attributes":[{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/UBERON_2000098"},{"subj":"T6","pred":"source","obj":"Anatomy-UBERON"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubmedHPO","color":"#aa93ec","default":true},{"id":"bionlp-st-epi-2011-training","color":"#96ec93"},{"id":"2015-BEL-Sample-2","color":"#ec93b0"},{"id":"HP-phenotype","color":"#93caec"},{"id":"mondo_disease","color":"#e4ec93"},{"id":"Anatomy-UBERON","color":"#da93ec"}]}]}}