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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 45-59 Glycan_Motif denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T2 52-59 Glycan_Motif denotes Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO
T4 128-142 Glycan_Motif denotes Sialyl Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T5 135-142 Glycan_Motif denotes Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO
T7 144-150 Glycan_Motif denotes sLe(x) https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T8 363-369 Glycan_Motif denotes sLe(x) https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T9 386-392 Glycan_Motif denotes Neu5Ac https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T10 798-804 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T11 901-907 Glycan_Motif denotes core 1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO
T12 1000-1006 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T13 1161-1167 Glycan_Motif denotes Neu5Ac https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 45-59 https://glytoucan.org/Structures/Glycans/G00054MO denotes sialyl Lewis x
T2 52-59 https://glytoucan.org/Structures/Glycans/G00051MO denotes Lewis x
T3 52-59 https://glytoucan.org/Structures/Glycans/G01187XC denotes Lewis x
T4 128-142 https://glytoucan.org/Structures/Glycans/G00054MO denotes Sialyl Lewis x
T5 135-142 https://glytoucan.org/Structures/Glycans/G00051MO denotes Lewis x
T6 135-142 https://glytoucan.org/Structures/Glycans/G01187XC denotes Lewis x
T7 144-150 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLe(x)
T8 363-369 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLe(x)
T9 386-392 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac
T10 901-907 https://glytoucan.org/Structures/Glycans/G00031MO denotes core 1
T11 1161-1167 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-127 Sentence denotes Complete enzymic synthesis of the mucin-type sialyl Lewis x epitope, involved in the interaction between PSGL-1 and P-selectin.
TextSentencer_T2 128-223 Sentence denotes Sialyl Lewis x (sLe(x)) is an established selectin ligand occurring on N- and O-linked glycans.
TextSentencer_T3 224-553 Sentence denotes Using a completely enzymic approach starting from p-nitrophenyl N-acetyl-alpha-D-galactosaminide (GalNAc(alpha1-pNp as core substrate, the sLe(x)-oligosaccharide Neu5Ac(alpha2-3)Gal(beta1-4)[Fuc(alpha1-3)]GlcNAc(beta1-6)[Gal(bet a1-3)]GalNAc(alpha1-pNp, representing the O-linked form, was synthesized in an overall yield of 32%.
TextSentencer_T4 554-735 Sentence denotes In a first step, Gal(beta1-3)GalNAc(alpha1-pNp was prepared in a yield of 52% using UDP-Gal and an enriched preparation of beta3-galactosyltransferase (EC 2.4.1.122) from rat liver.
TextSentencer_T5 736-995 Sentence denotes UDP-GlcNAc and a recombinant affinity-purified preparation of core 2 beta6-N-acetylglucosaminyltransferase (EC 2.4.1.102) fused to Protein A were used to branch the core 1 structure, affording GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc(alpha1-pNp in a yield of >85%.
TextSentencer_T6 996-1397 Sentence denotes The core 2 structure was galactosylated using UDP-Gal and purified human milk beta4-galactosyltransferase 1 (EC 2.4.1.38) (yield of >85%), then sialylated using CMP-Neu5Ac and purified recombinant alpha3-sialyltransferase 3 (EC 2.4.99.X) (yield of 87%), and finally fucosylated using GDP-Fuc and recombinant human alpha3-fucosyltransferase 6 (EC 2.4.1.152) produced in Pichia pastoris (yield of 100%).
TextSentencer_T7 1398-1443 Sentence denotes Overall 1.5 micromol of product was prepared.
TextSentencer_T8 1444-1547 Sentence denotes MALDI TOF mass spectra, and 1D and 2D TOCSY and ROESY 1H NMR analysis confirmed the obtained structure.
T1 0-127 Sentence denotes Complete enzymic synthesis of the mucin-type sialyl Lewis x epitope, involved in the interaction between PSGL-1 and P-selectin.
T2 128-223 Sentence denotes Sialyl Lewis x (sLe(x)) is an established selectin ligand occurring on N- and O-linked glycans.
T3 224-553 Sentence denotes Using a completely enzymic approach starting from p-nitrophenyl N-acetyl-alpha-D-galactosaminide (GalNAc(alpha1-pNp as core substrate, the sLe(x)-oligosaccharide Neu5Ac(alpha2-3)Gal(beta1-4)[Fuc(alpha1-3)]GlcNAc(beta1-6)[Gal(bet a1-3)]GalNAc(alpha1-pNp, representing the O-linked form, was synthesized in an overall yield of 32%.
T4 554-735 Sentence denotes In a first step, Gal(beta1-3)GalNAc(alpha1-pNp was prepared in a yield of 52% using UDP-Gal and an enriched preparation of beta3-galactosyltransferase (EC 2.4.1.122) from rat liver.
T5 736-995 Sentence denotes UDP-GlcNAc and a recombinant affinity-purified preparation of core 2 beta6-N-acetylglucosaminyltransferase (EC 2.4.1.102) fused to Protein A were used to branch the core 1 structure, affording GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc(alpha1-pNp in a yield of >85%.
T6 996-1397 Sentence denotes The core 2 structure was galactosylated using UDP-Gal and purified human milk beta4-galactosyltransferase 1 (EC 2.4.1.38) (yield of >85%), then sialylated using CMP-Neu5Ac and purified recombinant alpha3-sialyltransferase 3 (EC 2.4.99.X) (yield of 87%), and finally fucosylated using GDP-Fuc and recombinant human alpha3-fucosyltransferase 6 (EC 2.4.1.152) produced in Pichia pastoris (yield of 100%).
T7 1398-1443 Sentence denotes Overall 1.5 micromol of product was prepared.
T8 1444-1547 Sentence denotes MALDI TOF mass spectra, and 1D and 2D TOCSY and ROESY 1H NMR analysis confirmed the obtained structure.

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 45-59 http://www.glycoepitope.jp/epitopes/EP0012 denotes sialyl Lewis x
T2 52-59 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x
T3 128-142 http://www.glycoepitope.jp/epitopes/EP0012 denotes Sialyl Lewis x
T4 135-142 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 729-734 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver

NGLY1-deficiency

Id Subject Object Predicate Lexical cue
PD-NGLY1-deficiency-B_T1 429-435 chem:24139 denotes GlcNAc
PD-NGLY1-deficiency-B_T2 740-746 chem:24139 denotes GlcNAc
PD-NGLY1-deficiency-B_T3 929-935 chem:24139 denotes GlcNAc

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 729-734 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 144-147 Phenotype denotes sLe HP:0002725
T2 363-366 Phenotype denotes sLe HP:0002725

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 45-59 Glycan denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO
T2 128-142 Glycan denotes Sialyl Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO
T3 322-328 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T4 386-392 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T5 459-465 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T6 583-589 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T7 798-804 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T8 901-907 Glycan denotes core 1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO
T9 958-964 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T10 1000-1006 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T11 1161-1167 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 725-728 OrganismTaxon denotes rat 10114|10116
T3 1063-1068 OrganismTaxon denotes human 9606
T4 1304-1309 OrganismTaxon denotes human 9606
T5 1365-1380 OrganismTaxon denotes Pichia pastoris 4922

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 729-734 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T2 1069-1073 Body_part denotes milk http://purl.obolibrary.org/obo/UBERON_0001913

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 729-734 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-127 Sentence denotes Complete enzymic synthesis of the mucin-type sialyl Lewis x epitope, involved in the interaction between PSGL-1 and P-selectin.
TextSentencer_T2 128-223 Sentence denotes Sialyl Lewis x (sLe(x)) is an established selectin ligand occurring on N- and O-linked glycans.
TextSentencer_T3 224-553 Sentence denotes Using a completely enzymic approach starting from p-nitrophenyl N-acetyl-alpha-D-galactosaminide (GalNAc(alpha1-pNp as core substrate, the sLe(x)-oligosaccharide Neu5Ac(alpha2-3)Gal(beta1-4)[Fuc(alpha1-3)]GlcNAc(beta1-6)[Gal(bet a1-3)]GalNAc(alpha1-pNp, representing the O-linked form, was synthesized in an overall yield of 32%.
TextSentencer_T4 554-735 Sentence denotes In a first step, Gal(beta1-3)GalNAc(alpha1-pNp was prepared in a yield of 52% using UDP-Gal and an enriched preparation of beta3-galactosyltransferase (EC 2.4.1.122) from rat liver.
TextSentencer_T5 736-995 Sentence denotes UDP-GlcNAc and a recombinant affinity-purified preparation of core 2 beta6-N-acetylglucosaminyltransferase (EC 2.4.1.102) fused to Protein A were used to branch the core 1 structure, affording GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc(alpha1-pNp in a yield of >85%.
TextSentencer_T6 996-1397 Sentence denotes The core 2 structure was galactosylated using UDP-Gal and purified human milk beta4-galactosyltransferase 1 (EC 2.4.1.38) (yield of >85%), then sialylated using CMP-Neu5Ac and purified recombinant alpha3-sialyltransferase 3 (EC 2.4.99.X) (yield of 87%), and finally fucosylated using GDP-Fuc and recombinant human alpha3-fucosyltransferase 6 (EC 2.4.1.152) produced in Pichia pastoris (yield of 100%).
TextSentencer_T7 1398-1443 Sentence denotes Overall 1.5 micromol of product was prepared.
TextSentencer_T8 1444-1547 Sentence denotes MALDI TOF mass spectra, and 1D and 2D TOCSY and ROESY 1H NMR analysis confirmed the obtained structure.
T1 0-127 Sentence denotes Complete enzymic synthesis of the mucin-type sialyl Lewis x epitope, involved in the interaction between PSGL-1 and P-selectin.
T2 128-223 Sentence denotes Sialyl Lewis x (sLe(x)) is an established selectin ligand occurring on N- and O-linked glycans.
T3 224-553 Sentence denotes Using a completely enzymic approach starting from p-nitrophenyl N-acetyl-alpha-D-galactosaminide (GalNAc(alpha1-pNp as core substrate, the sLe(x)-oligosaccharide Neu5Ac(alpha2-3)Gal(beta1-4)[Fuc(alpha1-3)]GlcNAc(beta1-6)[Gal(bet a1-3)]GalNAc(alpha1-pNp, representing the O-linked form, was synthesized in an overall yield of 32%.
T4 554-735 Sentence denotes In a first step, Gal(beta1-3)GalNAc(alpha1-pNp was prepared in a yield of 52% using UDP-Gal and an enriched preparation of beta3-galactosyltransferase (EC 2.4.1.122) from rat liver.
T5 736-995 Sentence denotes UDP-GlcNAc and a recombinant affinity-purified preparation of core 2 beta6-N-acetylglucosaminyltransferase (EC 2.4.1.102) fused to Protein A were used to branch the core 1 structure, affording GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc(alpha1-pNp in a yield of >85%.
T6 996-1397 Sentence denotes The core 2 structure was galactosylated using UDP-Gal and purified human milk beta4-galactosyltransferase 1 (EC 2.4.1.38) (yield of >85%), then sialylated using CMP-Neu5Ac and purified recombinant alpha3-sialyltransferase 3 (EC 2.4.99.X) (yield of 87%), and finally fucosylated using GDP-Fuc and recombinant human alpha3-fucosyltransferase 6 (EC 2.4.1.152) produced in Pichia pastoris (yield of 100%).
T7 1398-1443 Sentence denotes Overall 1.5 micromol of product was prepared.
T8 1444-1547 Sentence denotes MALDI TOF mass spectra, and 1D and 2D TOCSY and ROESY 1H NMR analysis confirmed the obtained structure.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-127 Sentence denotes Complete enzymic synthesis of the mucin-type sialyl Lewis x epitope, involved in the interaction between PSGL-1 and P-selectin.
T2 128-223 Sentence denotes Sialyl Lewis x (sLe(x)) is an established selectin ligand occurring on N- and O-linked glycans.
T3 224-553 Sentence denotes Using a completely enzymic approach starting from p-nitrophenyl N-acetyl-alpha-D-galactosaminide (GalNAc(alpha1-pNp as core substrate, the sLe(x)-oligosaccharide Neu5Ac(alpha2-3)Gal(beta1-4)[Fuc(alpha1-3)]GlcNAc(beta1-6)[Gal(bet a1-3)]GalNAc(alpha1-pNp, representing the O-linked form, was synthesized in an overall yield of 32%.
T4 554-735 Sentence denotes In a first step, Gal(beta1-3)GalNAc(alpha1-pNp was prepared in a yield of 52% using UDP-Gal and an enriched preparation of beta3-galactosyltransferase (EC 2.4.1.122) from rat liver.
T5 736-995 Sentence denotes UDP-GlcNAc and a recombinant affinity-purified preparation of core 2 beta6-N-acetylglucosaminyltransferase (EC 2.4.1.102) fused to Protein A were used to branch the core 1 structure, affording GlcNAc(beta1-6)[Gal(beta1-3)]GalNAc(alpha1-pNp in a yield of >85%.
T6 996-1397 Sentence denotes The core 2 structure was galactosylated using UDP-Gal and purified human milk beta4-galactosyltransferase 1 (EC 2.4.1.38) (yield of >85%), then sialylated using CMP-Neu5Ac and purified recombinant alpha3-sialyltransferase 3 (EC 2.4.99.X) (yield of 87%), and finally fucosylated using GDP-Fuc and recombinant human alpha3-fucosyltransferase 6 (EC 2.4.1.152) produced in Pichia pastoris (yield of 100%).
T7 1398-1443 Sentence denotes Overall 1.5 micromol of product was prepared.
T8 1444-1547 Sentence denotes MALDI TOF mass spectra, and 1D and 2D TOCSY and ROESY 1H NMR analysis confirmed the obtained structure.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 45-59 Glycan denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO
T2 128-142 Glycan denotes Sialyl Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO
T3 322-328 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T4 386-392 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T5 459-465 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T6 583-589 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T7 798-804 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T8 901-907 Glycan denotes core 1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO
T9 958-964 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T10 1000-1006 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T11 1161-1167 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 45-59 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl Lewis x http://www.glycoepitope.jp/epitopes/EP0012
T2 128-142 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Sialyl Lewis x http://www.glycoepitope.jp/epitopes/EP0012

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 725-728 OrganismTaxon denotes rat 10114|10116
T3 1063-1068 OrganismTaxon denotes human 9606
T4 1304-1309 OrganismTaxon denotes human 9606
T5 1365-1380 OrganismTaxon denotes Pichia pastoris 4922

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 45-59 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl Lewis x http://www.glycoepitope.jp/epitopes/EP0012
T2 128-142 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Sialyl Lewis x http://www.glycoepitope.jp/epitopes/EP0012

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 729-734 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T2 1069-1073 Body_part denotes milk http://purl.obolibrary.org/obo/UBERON_0001913