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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-140 Sentence denotes A novel role for nitric oxide in the endogenous degradation of heparan sulfate during recycling of glypican-1 in vascular endothelial cells.
TextSentencer_T2 141-247 Sentence denotes We show here that the endothelial cell-line ECV 304 expresses the heparan sulfate proteoglycan glypican-1.
TextSentencer_T3 248-368 Sentence denotes The predominant cellular glycoform carries truncated side-chains and is accompanied by heparan sulfate oligosaccharides.
TextSentencer_T4 369-511 Sentence denotes Treatment with brefeldin A results in accumulation of a glypican proteoglycan with full-size side-chains while the oligosaccharides disappear.
TextSentencer_T5 512-699 Sentence denotes During chase the glypican proteoglycan is converted to partially degraded heparan sulfate chains and chain-truncated proteoglycan, both of which can be captured by treatment with suramin.
TextSentencer_T6 700-864 Sentence denotes The heparan sulfate chains in the intact proteoglycan can be depolymerized by nitrite-dependent cleavage at internally located N-unsubstituted glucosamine moieties.
TextSentencer_T7 865-1026 Sentence denotes Inhibition of NO-synthase or nitrite-deprivation prevents regeneration of intact proteoglycan from truncated precursors as well as formation of oligosaccharides.
TextSentencer_T8 1027-1127 Sentence denotes In nitrite-deprived cells, formation of glypican proteoglycan is restored when NO-donor is supplied.
TextSentencer_T9 1128-1261 Sentence denotes We propose that, in recycling glypican-1, heparan sulfate chains are cleaved at or near glucosamines with unsubstituted amino groups.
TextSentencer_T10 1262-1492 Sentence denotes NO-derived nitrite is then required for the removal of short, nonreducing terminal saccharides containing these N-unsubstituted glucosamine residues from the core protein stubs, facilitating re-synthesis of heparan sulfate chains.
T1 0-140 Sentence denotes A novel role for nitric oxide in the endogenous degradation of heparan sulfate during recycling of glypican-1 in vascular endothelial cells.
T2 141-247 Sentence denotes We show here that the endothelial cell-line ECV 304 expresses the heparan sulfate proteoglycan glypican-1.
T3 248-368 Sentence denotes The predominant cellular glycoform carries truncated side-chains and is accompanied by heparan sulfate oligosaccharides.
T4 369-511 Sentence denotes Treatment with brefeldin A results in accumulation of a glypican proteoglycan with full-size side-chains while the oligosaccharides disappear.
T5 512-699 Sentence denotes During chase the glypican proteoglycan is converted to partially degraded heparan sulfate chains and chain-truncated proteoglycan, both of which can be captured by treatment with suramin.
T6 700-864 Sentence denotes The heparan sulfate chains in the intact proteoglycan can be depolymerized by nitrite-dependent cleavage at internally located N-unsubstituted glucosamine moieties.
T7 865-1026 Sentence denotes Inhibition of NO-synthase or nitrite-deprivation prevents regeneration of intact proteoglycan from truncated precursors as well as formation of oligosaccharides.
T8 1027-1127 Sentence denotes In nitrite-deprived cells, formation of glypican proteoglycan is restored when NO-donor is supplied.
T9 1128-1261 Sentence denotes We propose that, in recycling glypican-1, heparan sulfate chains are cleaved at or near glucosamines with unsubstituted amino groups.
T10 1262-1492 Sentence denotes NO-derived nitrite is then required for the removal of short, nonreducing terminal saccharides containing these N-unsubstituted glucosamine residues from the core protein stubs, facilitating re-synthesis of heparan sulfate chains.
T1 0-140 Sentence denotes A novel role for nitric oxide in the endogenous degradation of heparan sulfate during recycling of glypican-1 in vascular endothelial cells.
T2 141-247 Sentence denotes We show here that the endothelial cell-line ECV 304 expresses the heparan sulfate proteoglycan glypican-1.
T3 248-368 Sentence denotes The predominant cellular glycoform carries truncated side-chains and is accompanied by heparan sulfate oligosaccharides.
T4 369-511 Sentence denotes Treatment with brefeldin A results in accumulation of a glypican proteoglycan with full-size side-chains while the oligosaccharides disappear.
T5 512-699 Sentence denotes During chase the glypican proteoglycan is converted to partially degraded heparan sulfate chains and chain-truncated proteoglycan, both of which can be captured by treatment with suramin.
T6 700-864 Sentence denotes The heparan sulfate chains in the intact proteoglycan can be depolymerized by nitrite-dependent cleavage at internally located N-unsubstituted glucosamine moieties.
T7 865-1026 Sentence denotes Inhibition of NO-synthase or nitrite-deprivation prevents regeneration of intact proteoglycan from truncated precursors as well as formation of oligosaccharides.
T8 1027-1127 Sentence denotes In nitrite-deprived cells, formation of glypican proteoglycan is restored when NO-donor is supplied.
T9 1128-1261 Sentence denotes We propose that, in recycling glypican-1, heparan sulfate chains are cleaved at or near glucosamines with unsubstituted amino groups.
T10 1262-1492 Sentence denotes NO-derived nitrite is then required for the removal of short, nonreducing terminal saccharides containing these N-unsubstituted glucosamine residues from the core protein stubs, facilitating re-synthesis of heparan sulfate chains.

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 63-78 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T2 207-222 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T3 335-350 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T4 586-601 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T5 704-719 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T6 1170-1185 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T7 1469-1484 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 63-70 FMAID:165191 denotes heparan
_T2 63-70 FMAID:67110 denotes heparan
_T3 63-78 FMAID:63023 denotes heparan sulfate
_T4 63-78 FMAID:167405 denotes heparan sulfate
_T5 122-133 FMAID:162384 denotes endothelial
_T6 122-133 FMAID:63916 denotes endothelial
_T7 122-139 FMAID:66772 denotes endothelial cells
_T8 122-139 FMAID:169653 denotes endothelial cells
_T9 122-139 FMAID:69075 denotes endothelial cells
_T10 122-139 FMAID:164926 denotes endothelial cells
_T11 134-139 FMAID:169002 denotes cells
_T12 134-139 FMAID:68646 denotes cells
_T13 163-174 FMAID:63916 denotes endothelial
_T14 163-174 FMAID:162384 denotes endothelial
_T15 163-179 FMAID:164926 denotes endothelial cell
_T16 163-179 FMAID:169653 denotes endothelial cell
_T17 163-179 FMAID:69075 denotes endothelial cell
_T18 163-179 FMAID:66772 denotes endothelial cell
_T19 207-214 FMAID:165191 denotes heparan
_T20 207-214 FMAID:67110 denotes heparan
_T21 207-222 FMAID:167405 denotes heparan sulfate
_T22 207-222 FMAID:63023 denotes heparan sulfate
_T23 207-235 FMAID:196834 denotes heparan sulfate proteoglycan
_T24 207-235 FMAID:82834 denotes heparan sulfate proteoglycan
_T25 223-235 FMAID:167397 denotes proteoglycan
_T26 223-235 FMAID:63015 denotes proteoglycan
_T27 335-342 FMAID:67110 denotes heparan
_T28 335-342 FMAID:165191 denotes heparan
_T29 335-350 FMAID:63023 denotes heparan sulfate
_T30 335-350 FMAID:167405 denotes heparan sulfate
_T31 351-367 FMAID:196731 denotes oligosaccharides
_T32 351-367 FMAID:82742 denotes oligosaccharides
_T33 434-446 FMAID:167397 denotes proteoglycan
_T34 434-446 FMAID:63015 denotes proteoglycan
_T35 484-500 FMAID:82742 denotes oligosaccharides
_T36 484-500 FMAID:196731 denotes oligosaccharides
_T37 538-550 FMAID:63015 denotes proteoglycan
_T38 538-550 FMAID:167397 denotes proteoglycan
_T39 586-593 FMAID:165191 denotes heparan
_T40 586-593 FMAID:67110 denotes heparan
_T41 586-601 FMAID:167405 denotes heparan sulfate
_T42 586-601 FMAID:63023 denotes heparan sulfate
_T43 629-641 FMAID:167397 denotes proteoglycan
_T44 629-641 FMAID:63015 denotes proteoglycan
_T45 704-711 FMAID:67110 denotes heparan
_T46 704-711 FMAID:165191 denotes heparan
_T47 704-719 FMAID:63023 denotes heparan sulfate
_T48 704-719 FMAID:167405 denotes heparan sulfate
_T49 741-753 FMAID:167397 denotes proteoglycan
_T50 741-753 FMAID:63015 denotes proteoglycan
_T51 808-818 FMAID:214710 denotes internally
_T52 843-854 FMAID:82797 denotes glucosamine
_T53 843-854 FMAID:196792 denotes glucosamine
_T54 946-958 FMAID:63015 denotes proteoglycan
_T55 946-958 FMAID:167397 denotes proteoglycan
_T56 1009-1025 FMAID:196731 denotes oligosaccharides
_T57 1009-1025 FMAID:82742 denotes oligosaccharides
_T58 1047-1052 FMAID:169002 denotes cells
_T59 1047-1052 FMAID:68646 denotes cells
_T60 1076-1088 FMAID:167397 denotes proteoglycan
_T61 1076-1088 FMAID:63015 denotes proteoglycan
_T62 1170-1177 FMAID:165191 denotes heparan
_T63 1170-1177 FMAID:67110 denotes heparan
_T64 1170-1185 FMAID:63023 denotes heparan sulfate
_T65 1170-1185 FMAID:167405 denotes heparan sulfate
_T66 1216-1228 FMAID:82797 denotes glucosamines
_T67 1216-1228 FMAID:196792 denotes glucosamines
_T68 1345-1356 FMAID:82744 denotes saccharides
_T69 1345-1356 FMAID:196733 denotes saccharides
_T70 1390-1401 FMAID:82797 denotes glucosamine
_T71 1390-1401 FMAID:196792 denotes glucosamine
_T72 1425-1432 FMAID:67257 denotes protein
_T73 1425-1432 FMAID:165447 denotes protein
_T74 1453-1455 FMAID:178331 denotes re
_T75 1469-1476 FMAID:67110 denotes heparan
_T76 1469-1476 FMAID:165191 denotes heparan
_T77 1469-1484 FMAID:63023 denotes heparan sulfate
_T78 1469-1484 FMAID:167405 denotes heparan sulfate

uniprot-human

Id Subject Object Predicate Lexical cue
T1 99-109 http://www.uniprot.org/uniprot/P35052 denotes glypican-1
T2 236-246 http://www.uniprot.org/uniprot/P35052 denotes glypican-1
T3 1158-1168 http://www.uniprot.org/uniprot/P35052 denotes glypican-1
T4 207-235 http://www.uniprot.org/uniprot/Q9UCB0 denotes heparan sulfate proteoglycan

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 99-109 http://www.uniprot.org/uniprot/Q9QZF2 denotes glypican-1
T2 236-246 http://www.uniprot.org/uniprot/Q9QZF2 denotes glypican-1
T3 1158-1168 http://www.uniprot.org/uniprot/Q9QZF2 denotes glypican-1

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 134-139 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T2 1047-1052 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T3 1254-1260 http://purl.bioontology.org/ontology/STY/T096 denotes groups

GO-BP

Id Subject Object Predicate Lexical cue
T1 48-59 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T2 577-585 http://purl.obolibrary.org/obo/GO_0009056 denotes degraded
T3 48-78 http://purl.obolibrary.org/obo/GO_0030200 denotes degradation of heparan sulfate
T4 207-235 http://purl.obolibrary.org/obo/GO_0030200 denotes heparan sulfate proteoglycan
T5 577-601 http://purl.obolibrary.org/obo/GO_0030200 denotes degraded heparan sulfate
T6 71-78 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T7 215-222 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T8 343-350 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T9 594-601 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T10 712-719 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T11 1178-1185 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T12 1477-1484 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T13 207-235 http://purl.obolibrary.org/obo/GO_0015012 denotes heparan sulfate proteoglycan
T14 1456-1484 http://purl.obolibrary.org/obo/GO_0015012 denotes synthesis of heparan sulfate
T15 207-235 http://purl.obolibrary.org/obo/GO_0030201 denotes heparan sulfate proteoglycan
T16 264-272 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T17 923-935 http://purl.obolibrary.org/obo/GO_0031099 denotes regeneration
T18 996-1005 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T19 1054-1063 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T20 996-1025 http://purl.obolibrary.org/obo/GO_0009312 denotes formation of oligosaccharides
T21 1456-1465 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis

GO-MF

Id Subject Object Predicate Lexical cue
T1 207-235 http://purl.obolibrary.org/obo/GO_0043395 denotes heparan sulfate proteoglycan

GO-CC

Id Subject Object Predicate Lexical cue
T1 134-139 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T2 175-179 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 1420-1424 http://purl.obolibrary.org/obo/GO_0019013 denotes core

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 1336-1344 http://edamontology.org/topic_0749 denotes terminal
T2 1425-1432 http://edamontology.org/topic_0078 denotes protein

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 993-1005 http://edamontology.org/format_1967 denotes as formation
T2 996-1005 http://edamontology.org/operation_0335 denotes formation
T3 996-1005 http://edamontology.org/format_1915 denotes formation
T4 1054-1063 http://edamontology.org/operation_0335 denotes formation
T5 1054-1063 http://edamontology.org/format_1915 denotes formation
T6 1402-1410 http://edamontology.org/data_1756 denotes residues
T7 1425-1432 http://edamontology.org/data_1467 denotes protein
T8 1425-1432 http://edamontology.org/format_1208 denotes protein

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 63-78 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
PD-GlycoEpitope-B_T2 207-222 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
PD-GlycoEpitope-B_T3 335-350 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
PD-GlycoEpitope-B_T4 586-601 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
PD-GlycoEpitope-B_T5 704-719 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
PD-GlycoEpitope-B_T6 1170-1185 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
PD-GlycoEpitope-B_T7 1469-1484 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-140 Sentence denotes A novel role for nitric oxide in the endogenous degradation of heparan sulfate during recycling of glypican-1 in vascular endothelial cells.
T2 141-247 Sentence denotes We show here that the endothelial cell-line ECV 304 expresses the heparan sulfate proteoglycan glypican-1.
T3 248-368 Sentence denotes The predominant cellular glycoform carries truncated side-chains and is accompanied by heparan sulfate oligosaccharides.
T4 369-511 Sentence denotes Treatment with brefeldin A results in accumulation of a glypican proteoglycan with full-size side-chains while the oligosaccharides disappear.
T5 512-699 Sentence denotes During chase the glypican proteoglycan is converted to partially degraded heparan sulfate chains and chain-truncated proteoglycan, both of which can be captured by treatment with suramin.
T6 700-864 Sentence denotes The heparan sulfate chains in the intact proteoglycan can be depolymerized by nitrite-dependent cleavage at internally located N-unsubstituted glucosamine moieties.
T7 865-1026 Sentence denotes Inhibition of NO-synthase or nitrite-deprivation prevents regeneration of intact proteoglycan from truncated precursors as well as formation of oligosaccharides.
T8 1027-1127 Sentence denotes In nitrite-deprived cells, formation of glypican proteoglycan is restored when NO-donor is supplied.
T9 1128-1261 Sentence denotes We propose that, in recycling glypican-1, heparan sulfate chains are cleaved at or near glucosamines with unsubstituted amino groups.
T10 1262-1492 Sentence denotes NO-derived nitrite is then required for the removal of short, nonreducing terminal saccharides containing these N-unsubstituted glucosamine residues from the core protein stubs, facilitating re-synthesis of heparan sulfate chains.

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 63-78 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T2 207-222 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T3 335-350 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T4 586-601 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T5 704-719 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T6 1170-1185 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T7 1469-1484 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 113-139 Body_part denotes vascular endothelial cells http://purl.obolibrary.org/obo/CL_0002139
T2 163-179 Body_part denotes endothelial cell http://purl.obolibrary.org/obo/CL_0000115

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 122-139 Body_part denotes endothelial cells FMA:66772
T2 163-179 Body_part denotes endothelial cell FMA:66772

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 113-139 Body_part denotes vascular endothelial cells http://purl.obolibrary.org/obo/CL_0002139
T2 163-179 Body_part denotes endothelial cell http://purl.obolibrary.org/obo/CL_0000115

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 113-139 Cell denotes vascular endothelial cells http://purl.obolibrary.org/obo/CL:0002139
T2 163-179 Cell denotes endothelial cell http://purl.obolibrary.org/obo/CL:0000115