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PubMed:10814696 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 5-12 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T2 1496-1503 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T3 1617-1624 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T4 1649-1656 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T5 1678-1684 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose
T6 1729-1736 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 5-12 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T2 1496-1503 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T3 1617-1624 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T4 1649-1656 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T5 1678-1684 Glycan_Motif denotes fucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO
T6 1729-1736 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-118 Sentence denotes High-mannose-type oligosaccharides from human placental arylsulfatase A are core fucosylated as confirmed by MALDI MS.
TextSentencer_T2 119-216 Sentence denotes Despite numerous studies on arylsulfatase A, the structure of its glycans is not well understood.
TextSentencer_T3 217-509 Sentence denotes It has been shown that the concentration of arylsulfatase A increases in the body fluids of patients with some forms of cancer, and the carbohydrate component of arylsulfatase A synthesized in tumor tissues and transformed cells undergoes increased sialylation, phosphorylation and sulfation.
TextSentencer_T4 510-692 Sentence denotes To understand the significance of any changes in the glycosylation of arylsulfatase A in cancer, it is important to know the structure of its carbohydrate component in normal tissue.
TextSentencer_T5 693-969 Sentence denotes In the present study we have analyzed carbohydrate moieties of human placental arylsylfatase A using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) followed by Western blotting on Immobilon P and on-blot deglycosylation using PNGase F for glycan release.
TextSentencer_T6 970-1082 Sentence denotes Profiles of N-glycans were obtained by matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS).
TextSentencer_T7 1083-1290 Sentence denotes Oligosaccharides were sequenced using specific exoglycosidases, and digestion products were analyzed by MALDI MS and the computer matching of the resulting masses with those derived from a sequence database.
TextSentencer_T8 1291-1416 Sentence denotes Fifty picomoles (6 microg) of arylsulfatase A applied to the gel were sufficient to characterize its oligosaccharide content.
TextSentencer_T9 1417-1569 Sentence denotes The results indicated that human placental arylsulfatase A possesses only high-mannose-type oligosaccharides, of which almost half are core fucosylated.
TextSentencer_T10 1570-1685 Sentence denotes In addition, there was a minor species of high-mannose-type glycan bearing six mannose residues with a core fucose.
TextSentencer_T11 1686-1845 Sentence denotes This structure was not expected since high-mannose-type oligosaccharides basically have not been recognized as a substrate for the alpha1,6-fucosyltransferase.
T1 0-118 Sentence denotes High-mannose-type oligosaccharides from human placental arylsulfatase A are core fucosylated as confirmed by MALDI MS.
T2 119-216 Sentence denotes Despite numerous studies on arylsulfatase A, the structure of its glycans is not well understood.
T3 217-509 Sentence denotes It has been shown that the concentration of arylsulfatase A increases in the body fluids of patients with some forms of cancer, and the carbohydrate component of arylsulfatase A synthesized in tumor tissues and transformed cells undergoes increased sialylation, phosphorylation and sulfation.
T4 510-692 Sentence denotes To understand the significance of any changes in the glycosylation of arylsulfatase A in cancer, it is important to know the structure of its carbohydrate component in normal tissue.
T5 693-969 Sentence denotes In the present study we have analyzed carbohydrate moieties of human placental arylsylfatase A using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) followed by Western blotting on Immobilon P and on-blot deglycosylation using PNGase F for glycan release.
T6 970-1082 Sentence denotes Profiles of N-glycans were obtained by matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS).
T7 1083-1290 Sentence denotes Oligosaccharides were sequenced using specific exoglycosidases, and digestion products were analyzed by MALDI MS and the computer matching of the resulting masses with those derived from a sequence database.
T8 1291-1416 Sentence denotes Fifty picomoles (6 microg) of arylsulfatase A applied to the gel were sufficient to characterize its oligosaccharide content.
T9 1417-1569 Sentence denotes The results indicated that human placental arylsulfatase A possesses only high-mannose-type oligosaccharides, of which almost half are core fucosylated.
T10 1570-1685 Sentence denotes In addition, there was a minor species of high-mannose-type glycan bearing six mannose residues with a core fucose.
T11 1686-1845 Sentence denotes This structure was not expected since high-mannose-type oligosaccharides basically have not been recognized as a substrate for the alpha1,6-fucosyltransferase.
T1 0-118 Sentence denotes High-mannose-type oligosaccharides from human placental arylsulfatase A are core fucosylated as confirmed by MALDI MS.
T2 119-216 Sentence denotes Despite numerous studies on arylsulfatase A, the structure of its glycans is not well understood.
T3 217-509 Sentence denotes It has been shown that the concentration of arylsulfatase A increases in the body fluids of patients with some forms of cancer, and the carbohydrate component of arylsulfatase A synthesized in tumor tissues and transformed cells undergoes increased sialylation, phosphorylation and sulfation.
T4 510-692 Sentence denotes To understand the significance of any changes in the glycosylation of arylsulfatase A in cancer, it is important to know the structure of its carbohydrate component in normal tissue.
T5 693-969 Sentence denotes In the present study we have analyzed carbohydrate moieties of human placental arylsylfatase A using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) followed by Western blotting on Immobilon P and on-blot deglycosylation using PNGase F for glycan release.
T6 970-1082 Sentence denotes Profiles of N-glycans were obtained by matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS).
T7 1083-1290 Sentence denotes Oligosaccharides were sequenced using specific exoglycosidases, and digestion products were analyzed by MALDI MS and the computer matching of the resulting masses with those derived from a sequence database.
T8 1291-1416 Sentence denotes Fifty picomoles (6 microg) of arylsulfatase A applied to the gel were sufficient to characterize its oligosaccharide content.
T9 1417-1569 Sentence denotes The results indicated that human placental arylsulfatase A possesses only high-mannose-type oligosaccharides, of which almost half are core fucosylated.
T10 1570-1685 Sentence denotes In addition, there was a minor species of high-mannose-type glycan bearing six mannose residues with a core fucose.
T11 1686-1845 Sentence denotes This structure was not expected since high-mannose-type oligosaccharides basically have not been recognized as a substrate for the alpha1,6-fucosyltransferase.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 5-12 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T2 1496-1503 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T3 1617-1624 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T4 1649-1656 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T5 1678-1684 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose
T6 1729-1736 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 337-343 HP_0002664 denotes cancer
T2 410-415 HP_0002664 denotes tumor
T3 599-605 HP_0002664 denotes cancer

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 5-12 FMAID:196796 denotes mannose
_T2 5-12 FMAID:82801 denotes mannose
_T3 18-34 FMAID:82742 denotes oligosaccharides
_T4 18-34 FMAID:196731 denotes oligosaccharides
_T5 294-298 FMAID:256135 denotes body
_T6 294-298 FMAID:256134 denotes body
_T7 294-305 FMAID:280617 denotes body fluids
_T8 353-365 FMAID:197276 denotes carbohydrate
_T9 353-365 FMAID:82737 denotes carbohydrate
_T10 416-423 FMAID:256050 denotes tissues
_T11 440-445 FMAID:169002 denotes cells
_T12 440-445 FMAID:68646 denotes cells
_T13 652-664 FMAID:197276 denotes carbohydrate
_T14 652-664 FMAID:82737 denotes carbohydrate
_T15 685-691 FMAID:256050 denotes tissue
_T16 731-743 FMAID:197276 denotes carbohydrate
_T17 731-743 FMAID:82737 denotes carbohydrate
_T18 1083-1099 FMAID:82742 denotes Oligosaccharides
_T19 1083-1099 FMAID:196731 denotes Oligosaccharides
_T20 1392-1407 FMAID:196731 denotes oligosaccharide
_T21 1392-1407 FMAID:82742 denotes oligosaccharide
_T22 1496-1503 FMAID:196796 denotes mannose
_T23 1496-1503 FMAID:82801 denotes mannose
_T24 1509-1525 FMAID:82742 denotes oligosaccharides
_T25 1509-1525 FMAID:196731 denotes oligosaccharides
_T26 1617-1624 FMAID:82801 denotes mannose
_T27 1617-1624 FMAID:196796 denotes mannose
_T28 1649-1656 FMAID:82801 denotes mannose
_T29 1649-1656 FMAID:196796 denotes mannose
_T30 1678-1684 FMAID:196784 denotes fucose
_T31 1678-1684 FMAID:82790 denotes fucose
_T32 1729-1736 FMAID:82801 denotes mannose
_T33 1729-1736 FMAID:196796 denotes mannose
_T34 1742-1758 FMAID:82742 denotes oligosaccharides
_T35 1742-1758 FMAID:196731 denotes oligosaccharides

uniprot-human

Id Subject Object Predicate Lexical cue
T1 115-117 http://www.uniprot.org/uniprot/Q99707 denotes MS
T2 1078-1080 http://www.uniprot.org/uniprot/Q99707 denotes MS
T3 1193-1195 http://www.uniprot.org/uniprot/Q99707 denotes MS
T4 147-162 http://www.uniprot.org/uniprot/P15289 denotes arylsulfatase A
T5 853-856 http://www.uniprot.org/uniprot/P20132 denotes SDS
T6 941-947 http://www.uniprot.org/uniprot/Q96IV0 denotes PNGase

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 115-117 http://www.uniprot.org/uniprot/A6H5Y3 denotes MS
T2 1078-1080 http://www.uniprot.org/uniprot/A6H5Y3 denotes MS
T3 1193-1195 http://www.uniprot.org/uniprot/A6H5Y3 denotes MS
T4 147-162 http://www.uniprot.org/uniprot/P50428 denotes arylsulfatase A
T5 941-947 http://www.uniprot.org/uniprot/Q9JI78 denotes PNGase

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 337-343 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T2 416-423 http://purl.bioontology.org/ontology/STY/T024 denotes tissues
T3 440-445 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T4 599-605 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T5 685-691 http://purl.bioontology.org/ontology/STY/T024 denotes tissue
T6 1025-1030 http://purl.bioontology.org/ontology/NCBITAXON/62990 denotes laser

GO-BP

Id Subject Object Predicate Lexical cue
T1 46-55 http://purl.obolibrary.org/obo/GO_0001890 denotes placental
T2 762-771 http://purl.obolibrary.org/obo/GO_0001890 denotes placental
T3 1450-1459 http://purl.obolibrary.org/obo/GO_0001890 denotes placental
T4 81-92 http://purl.obolibrary.org/obo/GO_0036065 denotes fucosylated
T5 1557-1568 http://purl.obolibrary.org/obo/GO_0036065 denotes fucosylated
T6 466-477 http://purl.obolibrary.org/obo/GO_0097503 denotes sialylation
T7 479-494 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T8 499-508 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfation
T9 809-816 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T10 563-576 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T11 941-947 http://purl.obolibrary.org/obo/GO_0000224 denotes PNGase
T12 941-949 http://purl.obolibrary.org/obo/GO_0000224 denotes PNGase F
T13 1151-1160 http://purl.obolibrary.org/obo/GO_0007586 denotes digestion

GO-CC

Id Subject Object Predicate Lexical cue
T1 76-80 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T2 1552-1556 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T3 1673-1677 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T4 440-445 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 416-423 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
T2 685-691 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 40-45 http://edamontology.org/topic_2815 denotes human
T2 136-143 http://edamontology.org/topic_3678 denotes studies
T3 337-343 http://edamontology.org/topic_2640 denotes cancer
T4 353-365 http://edamontology.org/topic_0152 denotes carbohydrate
T5 599-605 http://edamontology.org/topic_2640 denotes cancer
T6 652-664 http://edamontology.org/topic_0152 denotes carbohydrate
T7 708-713 http://edamontology.org/topic_3678 denotes study
T8 731-743 http://edamontology.org/topic_0152 denotes carbohydrate
T9 756-761 http://edamontology.org/topic_2815 denotes human
T10 1053-1070 http://edamontology.org/topic_0134 denotes mass spectrometry
T11 1053-1070 http://edamontology.org/topic_3520 denotes mass spectrometry
T12 1105-1114 http://edamontology.org/topic_3168 denotes sequenced
T13 1105-1114 http://edamontology.org/topic_0080 denotes sequenced
T14 1272-1280 http://edamontology.org/topic_3168 denotes sequence
T15 1272-1280 http://edamontology.org/topic_0080 denotes sequence
T16 1272-1289 http://edamontology.org/topic_3041 denotes sequence database
T17 1272-1289 http://edamontology.org/topic_0080 denotes sequence database
T18 1281-1289 http://edamontology.org/topic_3489 denotes database
T19 1444-1449 http://edamontology.org/topic_2815 denotes human

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 168-177 http://edamontology.org/data_0883 denotes structure
T2 244-257 http://edamontology.org/data_2140 denotes concentration
T3 635-644 http://edamontology.org/data_0883 denotes structure
T4 678-684 http://edamontology.org/operation_3435 denotes normal
T5 1009-1015 http://edamontology.org/data_2082 denotes matrix
T6 1053-1070 http://edamontology.org/data_2536 denotes mass spectrometry
T7 1053-1070 http://edamontology.org/data_3147 denotes mass spectrometry
T8 1105-1114 http://edamontology.org/data_2044 denotes sequenced
T9 1105-1114 http://edamontology.org/operation_3218 denotes sequenced
T10 1213-1221 http://edamontology.org/format_1990 denotes matching
T11 1272-1280 http://edamontology.org/data_2044 denotes sequence
T12 1272-1280 http://edamontology.org/operation_3218 denotes sequence
T13 1272-1289 http://edamontology.org/data_1057 denotes sequence database
T14 1272-1289 http://edamontology.org/data_0857 denotes sequence database
T15 1272-1289 http://edamontology.org/data_2925 denotes sequence database
T16 1281-1289 http://edamontology.org/data_0581 denotes database
T17 1657-1665 http://edamontology.org/data_1756 denotes residues
T18 1691-1700 http://edamontology.org/data_0883 denotes structure

NGLY1-deficiency

Id Subject Object Predicate Lexical cue
PD-NGLY1-deficiency-B_T1 941-947 hgnc:17646 denotes PNGase

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 0-12 http://rdf.glycoinfo.org/glycan/G00028MO denotes High-mannose
T2 1491-1503 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose
T3 1612-1624 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose
T4 1724-1736 http://rdf.glycoinfo.org/glycan/G00028MO denotes high-mannose
T5 982-991 http://rdf.glycoinfo.org/glycan/G00027MO denotes N-glycans

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 416-423 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T2 685-691 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T3 46-55 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placental
PD-UBERON-AE-B_T4 762-771 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placental
PD-UBERON-AE-B_T5 1450-1459 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placental

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 337-343 Phenotype denotes cancer HP:0002664
T2 410-415 Phenotype denotes tumor HP:0002664
T3 599-605 Phenotype denotes cancer HP:0002664

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 337-343 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T2 410-415 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T3 599-605 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 40-45 OrganismTaxon denotes human 9606
T2 756-761 OrganismTaxon denotes human 9606
T3 1444-1449 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 294-305 Body_part denotes body fluids http://purl.obolibrary.org/obo/UBERON_0006314
T2 685-691 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479