PubMed:10783264 JSONTXT

{"project":"ggdb-test","denotations":[{"id":"T1","span":{"begin":855,"end":861},"obj":"https://acgg.asia/db/ggdb/info/gg157"}],"text":"Cloning and chromosomal mapping of human glucuronyltransferase involved in biosynthesis of the HNK-1 carbohydrate epitope.\nThe HNK-1 carbohydrate is expressed on various cell adhesion molecules in the nervous system and is suggested to play a role in cell-cell and cell-substrate interactions. Here we describe the isolation of a cDNA encoding human glucuronyltransferase (GlcAT-P), which is a key enzyme in the biosynthesis of the HNK-1 carbohydrate. The primary structure deduced from the cDNA sequence predicted a type II transmembrane protein of 334 amino acids. Human GlcAT-P was 98.2% identical with rat GlcAT-P in amino acid sequence, the exception being the length of the cytoplasmic tail. Northern blot analysis indicated that human GlcAT-P is expressed mainly in the brain. There is a single copy of the human GlcAT-P gene (HGMW-approved symbol B3GAT1), and it was mapped to chromosome 11q25."}

{"project":"GGDB-2020","denotations":[{"id":"T1","span":{"begin":855,"end":861},"obj":"https://acgg.asia/db/ggdb/info/gg157"}],"text":"Cloning and chromosomal mapping of human glucuronyltransferase involved in biosynthesis of the HNK-1 carbohydrate epitope.\nThe HNK-1 carbohydrate is expressed on various cell adhesion molecules in the nervous system and is suggested to play a role in cell-cell and cell-substrate interactions. Here we describe the isolation of a cDNA encoding human glucuronyltransferase (GlcAT-P), which is a key enzyme in the biosynthesis of the HNK-1 carbohydrate. The primary structure deduced from the cDNA sequence predicted a type II transmembrane protein of 334 amino acids. Human GlcAT-P was 98.2% identical with rat GlcAT-P in amino acid sequence, the exception being the length of the cytoplasmic tail. Northern blot analysis indicated that human GlcAT-P is expressed mainly in the brain. There is a single copy of the human GlcAT-P gene (HGMW-approved symbol B3GAT1), and it was mapped to chromosome 11q25."}

{"project":"glycogenes","denotations":[{"id":"PD-GlycoGenes20190927-B_T1","span":{"begin":373,"end":380},"obj":"https://acgg.asia/db/ggdb/info/gg157"},{"id":"PD-GlycoGenes20190927-B_T2","span":{"begin":522,"end":524},"obj":"https://acgg.asia/db/ggdb/info/gg111"},{"id":"PD-GlycoGenes20190927-B_T3","span":{"begin":573,"end":580},"obj":"https://acgg.asia/db/ggdb/info/gg157"},{"id":"PD-GlycoGenes20190927-B_T4","span":{"begin":610,"end":617},"obj":"https://acgg.asia/db/ggdb/info/gg157"},{"id":"PD-GlycoGenes20190927-B_T5","span":{"begin":742,"end":749},"obj":"https://acgg.asia/db/ggdb/info/gg157"},{"id":"PD-GlycoGenes20190927-B_T6","span":{"begin":820,"end":827},"obj":"https://acgg.asia/db/ggdb/info/gg157"},{"id":"PD-GlycoGenes20190927-B_T7","span":{"begin":848,"end":854},"obj":"url"},{"id":"PD-GlycoGenes20190927-B_T8","span":{"begin":855,"end":861},"obj":"https://acgg.asia/db/ggdb/info/gg157"}],"text":"Cloning and chromosomal mapping of human glucuronyltransferase involved in biosynthesis of the HNK-1 carbohydrate epitope.\nThe HNK-1 carbohydrate is expressed on various cell adhesion molecules in the nervous system and is suggested to play a role in cell-cell and cell-substrate interactions. Here we describe the isolation of a cDNA encoding human glucuronyltransferase (GlcAT-P), which is a key enzyme in the biosynthesis of the HNK-1 carbohydrate. The primary structure deduced from the cDNA sequence predicted a type II transmembrane protein of 334 amino acids. Human GlcAT-P was 98.2% identical with rat GlcAT-P in amino acid sequence, the exception being the length of the cytoplasmic tail. Northern blot analysis indicated that human GlcAT-P is expressed mainly in the brain. There is a single copy of the human GlcAT-P gene (HGMW-approved symbol B3GAT1), and it was mapped to chromosome 11q25."}