PubMed:10673652 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/10673652","sourcedb":"PubMed","sourceid":"10673652","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/10673652","text":"Oral staphylococcal mucositis: A new clinical entity in orofacial granulomatosis and Crohn's disease.\nOBJECTIVE: Orofacial granulomatosis and the oral manifestations of Crohn's disease comprise many clinical features, of which stomatitis is one. The purpose of this study was to establish a role for Staphylococcus aureus in mucositis affecting some patients with orofacial granulomatosis or oral Crohn's disease.\nSTUDY DESIGN: Four patients (2 with orofacial granulomatosis and 2 with oral Crohn's disease), from a total of 450 patients examined over 10 years, had stomatitis involving the entire oral mucosa, from which S aureus was cultured by the oral rinse technique. These patients were treated with flucloxacillin or erythromycin.\nRESULTS: A heavy growth of S aureus was isolated from the mouth of each patient. All 4 patients responded to treatment with flucloxacillin or erythromycin.\nCONCLUSIONS: S aureus is a potential cause of panstomatitis in patients with orofacial granulomatosis or Crohn's disease. 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