PubMed:10673652 JSONTXT

{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":123,"end":137},"obj":"HP_0002955"},{"id":"T2","span":{"begin":169,"end":184},"obj":"HP_0100280"},{"id":"T3","span":{"begin":374,"end":388},"obj":"HP_0002955"},{"id":"T4","span":{"begin":397,"end":412},"obj":"HP_0100280"}],"text":"Oral staphylococcal mucositis: A new clinical entity in orofacial granulomatosis and Crohn's disease.\nOBJECTIVE: Orofacial granulomatosis and the oral manifestations of Crohn's disease comprise many clinical features, of which stomatitis is one. The purpose of this study was to establish a role for Staphylococcus aureus in mucositis affecting some patients with orofacial granulomatosis or oral Crohn's disease.\nSTUDY DESIGN: Four patients (2 with orofacial granulomatosis and 2 with oral Crohn's disease), from a total of 450 patients examined over 10 years, had stomatitis involving the entire oral mucosa, from which S aureus was cultured by the oral rinse technique. These patients were treated with flucloxacillin or erythromycin.\nRESULTS: A heavy growth of S aureus was isolated from the mouth of each patient. All 4 patients responded to treatment with flucloxacillin or erythromycin.\nCONCLUSIONS: S aureus is a potential cause of panstomatitis in patients with orofacial granulomatosis or Crohn's disease. This infection responds rapidly to antimicrobial treatment."}

{"project":"disease_gene_microbe_small","denotations":[{"id":"T0","span":{"begin":20,"end":29},"obj":"DOID:0080178"},{"id":"T1","span":{"begin":85,"end":100},"obj":"DOID:8778"},{"id":"T2","span":{"begin":170,"end":185},"obj":"DOID:8778"},{"id":"T3","span":{"begin":228,"end":238},"obj":"DOID:9637"},{"id":"T4","span":{"begin":326,"end":335},"obj":"DOID:0080178"},{"id":"T5","span":{"begin":398,"end":413},"obj":"DOID:8778"},{"id":"T6","span":{"begin":492,"end":507},"obj":"DOID:8778"},{"id":"T7","span":{"begin":567,"end":577},"obj":"DOID:9637"},{"id":"T8","span":{"begin":1000,"end":1015},"obj":"DOID:8778"},{"id":"T9","span":{"begin":5,"end":19},"obj":"taxonomy:1279"},{"id":"T10","span":{"begin":301,"end":322},"obj":"taxonomy:1280"},{"id":"T11","span":{"begin":623,"end":631},"obj":"taxonomy:1280"},{"id":"T12","span":{"begin":766,"end":774},"obj":"taxonomy:1280"},{"id":"T13","span":{"begin":908,"end":916},"obj":"taxonomy:1280"}],"namespaces":[{"prefix":"DOID","uri":"http://disease-ontology.org/term/DOID:"},{"prefix":"taxonomy","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info\u0026id="}],"text":"Oral staphylococcal mucositis: A new clinical entity in orofacial granulomatosis and Crohn's disease.\nOBJECTIVE: Orofacial granulomatosis and the oral manifestations of Crohn's disease comprise many clinical features, of which stomatitis is one. The purpose of this study was to establish a role for Staphylococcus aureus in mucositis affecting some patients with orofacial granulomatosis or oral Crohn's disease.\nSTUDY DESIGN: Four patients (2 with orofacial granulomatosis and 2 with oral Crohn's disease), from a total of 450 patients examined over 10 years, had stomatitis involving the entire oral mucosa, from which S aureus was cultured by the oral rinse technique. These patients were treated with flucloxacillin or erythromycin.\nRESULTS: A heavy growth of S aureus was isolated from the mouth of each patient. All 4 patients responded to treatment with flucloxacillin or erythromycin.\nCONCLUSIONS: S aureus is a potential cause of panstomatitis in patients with orofacial granulomatosis or Crohn's disease. This infection responds rapidly to antimicrobial treatment."}

{"project":"PubCasesHPO","denotations":[{"id":"AB1","span":{"begin":123,"end":137},"obj":"HP:0002955"},{"id":"AB2","span":{"begin":169,"end":184},"obj":"HP:0100280"},{"id":"TI1","span":{"begin":66,"end":80},"obj":"HP:0002955"},{"id":"TI2","span":{"begin":85,"end":100},"obj":"HP:0100280"},{"id":"AB3","span":{"begin":227,"end":237},"obj":"HP:0010280"},{"id":"AB4","span":{"begin":374,"end":388},"obj":"HP:0002955"},{"id":"AB5","span":{"begin":397,"end":412},"obj":"HP:0100280"},{"id":"AB6","span":{"begin":460,"end":474},"obj":"HP:0002955"},{"id":"AB7","span":{"begin":491,"end":506},"obj":"HP:0100280"},{"id":"AB8","span":{"begin":566,"end":576},"obj":"HP:0010280"},{"id":"AB9","span":{"begin":981,"end":995},"obj":"HP:0002955"},{"id":"AB10","span":{"begin":999,"end":1014},"obj":"HP:0100280"}],"text":"Oral staphylococcal mucositis: A new clinical entity in orofacial granulomatosis and Crohn's disease.\nOBJECTIVE: Orofacial granulomatosis and the oral manifestations of Crohn's disease comprise many clinical features, of which stomatitis is one. The purpose of this study was to establish a role for Staphylococcus aureus in mucositis affecting some patients with orofacial granulomatosis or oral Crohn's disease.\nSTUDY DESIGN: Four patients (2 with orofacial granulomatosis and 2 with oral Crohn's disease), from a total of 450 patients examined over 10 years, had stomatitis involving the entire oral mucosa, from which S aureus was cultured by the oral rinse technique. These patients were treated with flucloxacillin or erythromycin.\nRESULTS: A heavy growth of S aureus was isolated from the mouth of each patient. All 4 patients responded to treatment with flucloxacillin or erythromycin.\nCONCLUSIONS: S aureus is a potential cause of panstomatitis in patients with orofacial granulomatosis or Crohn's disease. This infection responds rapidly to antimicrobial treatment."}