PubMed:10570220
Annnotations
GlyCosmos15-Species
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 68 | 1458-1466 | Species | denotes | HIV-1LAI | |
| 73 | 1661-1666 | Species | denotes | HIV-1 | 11676 |
Glycan-Motif
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 411-418 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T2 | 411-418 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T3 | 422-433 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T4 | 759-766 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T5 | 759-766 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T6 | 771-782 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T7 | 1035-1042 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T8 | 1035-1042 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T9 | 1046-1057 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T10 | 1103-1110 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
| T11 | 1236-1243 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T12 | 1236-1243 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T13 | 1256-1263 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
| T14 | 1367-1374 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T15 | 1367-1374 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T16 | 1376-1387 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T17 | 1588-1595 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T18 | 1588-1595 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 411-418 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
| T3 | 422-433 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T4 | 759-766 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
| T6 | 771-782 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T7 | 1035-1042 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
| T9 | 1046-1057 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T10 | 1103-1110 | Glycan_Motif | denotes | mannose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ |
| T11 | 1236-1243 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
| T13 | 1256-1263 | Glycan_Motif | denotes | mannose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ |
| T14 | 1367-1374 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
| T16 | 1376-1387 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T17 | 1588-1595 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 411-418 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T2 | 411-418 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T3 | 422-433 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T4 | 759-766 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T5 | 759-766 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T6 | 771-782 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T7 | 1035-1042 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T8 | 1035-1042 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T9 | 1046-1057 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T10 | 1103-1110 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
| T11 | 1236-1243 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T12 | 1236-1243 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T13 | 1256-1263 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
| T14 | 1367-1374 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T15 | 1367-1374 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T16 | 1376-1387 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T17 | 1588-1595 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T18 | 1588-1595 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 422-433 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T2 | 771-782 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T3 | 1046-1057 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T4 | 1376-1387 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 11-28 | FMAID:63011 | denotes | glycosaminoglycan |
| _T2 | 11-28 | FMAID:167395 | denotes | glycosaminoglycan |
| _T3 | 51-63 | FMAID:83624 | denotes | stromal cell |
| _T4 | 51-63 | FMAID:197708 | denotes | stromal cell |
| _T5 | 111-123 | FMAID:200942 | denotes | cell surface |
| _T6 | 111-123 | FMAID:212684 | denotes | cell surface |
| _T7 | 116-123 | FMAID:50594 | denotes | surface |
| _T8 | 116-123 | FMAID:146300 | denotes | surface |
| _T9 | 124-142 | FMAID:63011 | denotes | glycosaminoglycans |
| _T10 | 124-142 | FMAID:167395 | denotes | glycosaminoglycans |
| _T11 | 144-148 | FMAID:167404 | denotes | GAGs |
| _T12 | 181-193 | FMAID:197708 | denotes | stromal cell |
| _T13 | 181-193 | FMAID:83624 | denotes | stromal cell |
| _T14 | 231-243 | FMAID:198000 | denotes | lymphoid CEM |
| _T15 | 231-243 | FMAID:84065 | denotes | lymphoid CEM |
| _T16 | 247-256 | FMAID:62864 | denotes | monocytic |
| _T17 | 247-256 | FMAID:167164 | denotes | monocytic |
| _T18 | 262-267 | FMAID:169002 | denotes | cells |
| _T19 | 262-267 | FMAID:68646 | denotes | cells |
| _T20 | 297-302 | FMAID:169002 | denotes | cells |
| _T21 | 297-302 | FMAID:68646 | denotes | cells |
| _T22 | 411-418 | FMAID:167420 | denotes | heparin |
| _T23 | 411-418 | FMAID:82839 | denotes | heparin |
| _T24 | 422-441 | FMAID:82837 | denotes | chondroitin sulfate |
| _T25 | 422-441 | FMAID:196838 | denotes | chondroitin sulfate |
| _T26 | 505-510 | FMAID:68646 | denotes | cells |
| _T27 | 505-510 | FMAID:169002 | denotes | cells |
| _T28 | 639-643 | FMAID:167404 | denotes | GAGs |
| _T29 | 676-681 | FMAID:169002 | denotes | cells |
| _T30 | 676-681 | FMAID:68646 | denotes | cells |
| _T31 | 759-766 | FMAID:167420 | denotes | heparin |
| _T32 | 759-766 | FMAID:82839 | denotes | heparin |
| _T33 | 771-790 | FMAID:82837 | denotes | chondroitin sulfate |
| _T34 | 771-790 | FMAID:196838 | denotes | chondroitin sulfate |
| _T35 | 858-863 | FMAID:169002 | denotes | cells |
| _T36 | 858-863 | FMAID:68646 | denotes | cells |
| _T37 | 882-886 | FMAID:167404 | denotes | GAGs |
| _T38 | 975-980 | FMAID:169002 | denotes | cells |
| _T39 | 975-980 | FMAID:68646 | denotes | cells |
| _T40 | 1035-1042 | FMAID:167420 | denotes | heparin |
| _T41 | 1035-1042 | FMAID:82839 | denotes | heparin |
| _T42 | 1046-1065 | FMAID:196838 | denotes | chondroitin sulfate |
| _T43 | 1046-1065 | FMAID:82837 | denotes | chondroitin sulfate |
| _T44 | 1097-1101 | FMAID:167404 | denotes | GAGs |
| _T45 | 1103-1110 | FMAID:196796 | denotes | mannose |
| _T46 | 1103-1110 | FMAID:82801 | denotes | mannose |
| _T47 | 1183-1188 | FMAID:68646 | denotes | cells |
| _T48 | 1183-1188 | FMAID:169002 | denotes | cells |
| _T49 | 1236-1243 | FMAID:82839 | denotes | heparin |
| _T50 | 1236-1243 | FMAID:167420 | denotes | heparin |
| _T51 | 1256-1263 | FMAID:196796 | denotes | mannose |
| _T52 | 1256-1263 | FMAID:82801 | denotes | mannose |
| _T53 | 1367-1374 | FMAID:167420 | denotes | heparin |
| _T54 | 1367-1374 | FMAID:82839 | denotes | heparin |
| _T55 | 1376-1395 | FMAID:196838 | denotes | chondroitin sulfate |
| _T56 | 1376-1395 | FMAID:82837 | denotes | chondroitin sulfate |
| _T57 | 1485-1497 | FMAID:197276 | denotes | carbohydrate |
| _T58 | 1485-1497 | FMAID:82737 | denotes | carbohydrate |
| _T59 | 1573-1577 | FMAID:167404 | denotes | GAGs |
| _T60 | 1588-1595 | FMAID:167420 | denotes | heparin |
| _T61 | 1588-1595 | FMAID:82839 | denotes | heparin |
| _T62 | 1701-1705 | FMAID:167404 | denotes | GAGs |
| _T63 | 1725-1737 | FMAID:200942 | denotes | cell surface |
| _T64 | 1725-1737 | FMAID:212684 | denotes | cell surface |
| _T65 | 1730-1737 | FMAID:146300 | denotes | surface |
| _T66 | 1730-1737 | FMAID:50594 | denotes | surface |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 225-228 | http://www.uniprot.org/uniprot/P01730 | denotes | CD4 |
| T2 | 324-338 | http://www.uniprot.org/uniprot/P34059 | denotes | chondroitinase |
| T3 | 724-738 | http://www.uniprot.org/uniprot/P34059 | denotes | chondroitinase |
| T4 | 1439-1444 | http://www.uniprot.org/uniprot/Q14624 | denotes | gp120 |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 225-228 | http://www.uniprot.org/uniprot/P06332 | denotes | CD4 |
| T2 | 324-338 | http://www.uniprot.org/uniprot/Q571E4 | denotes | chondroitinase |
| T3 | 724-738 | http://www.uniprot.org/uniprot/Q571E4 | denotes | chondroitinase |
| T4 | 1667-1670 | http://www.uniprot.org/uniprot/P11370 | denotes | Env |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 262-267 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T2 | 297-302 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T3 | 505-510 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T4 | 676-681 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T5 | 858-863 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T6 | 975-980 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T7 | 1183-1188 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-92 | Sentence | denotes | Glycan and glycosaminoglycan binding properties of stromal cell-derived factor (SDF)-1alpha. |
| TextSentencer_T2 | 93-402 | Sentence | denotes | We show here that cell surface glycosaminoglycans (GAGs) are involved in the binding of stromal cell-derived factor (SDF)-1alpha to CD4(+)lymphoid CEM or monocytic U937 cells, inasmuch as pretreating the cells with heparitinase or chondroitinase inhibits SDF-1alpha binding by 40-41% and 31-35%, respectively. |
| TextSentencer_T3 | 403-587 | Sentence | denotes | Soluble heparin or chondroitin sulfate partially but significantly inhibits SDF-1alpha binding to the cells by 45-52% and 42-56%, respectively, while dextran has no significant effect. |
| TextSentencer_T4 | 588-682 | Sentence | denotes | Taken together, these results indicate the role of GAGs in SDF-1alpha attachment to the cells. |
| TextSentencer_T5 | 683-919 | Sentence | denotes | However, the effects of heparitinase and chondroitinase as well as those of heparin and chondroitin sulfate are not additive, which suggests that SDF-1alpha may attach to the cells through different GAGs, and also through other ligands. |
| TextSentencer_T6 | 920-991 | Sentence | denotes | Soluble mannan also inhibits SDF-1alpha binding to the cells by 30-33%. |
| TextSentencer_T7 | 992-1078 | Sentence | denotes | Additivity between this effect and that of heparin or chondroitin sulfate is observed. |
| TextSentencer_T8 | 1079-1189 | Sentence | denotes | Therefore, beside GAGs, mannose-containing species may also be involved in SDF-1alpha attachment to the cells. |
| TextSentencer_T9 | 1190-1408 | Sentence | denotes | Accordingly, SDF-1alpha specifically binds to heparin-agarose and mannose-divinylsulfone agarose affinity matrices, and these interactions are inhibited respectively by soluble heparin, chondroitin sulfate, and mannan. |
| TextSentencer_T10 | 1409-1596 | Sentence | denotes | We have previously shown that gp120 of X4 strain HIV-1LAI presents specific carbohydrate-binding properties for mannosylated derivatives, including mannan, and for GAGs including heparin. |
| TextSentencer_T11 | 1597-1738 | Sentence | denotes | The present data therefore indicate that, in the same manner as HIV-1 Env, SDF-1alpha can interact with GAGs and glycans at the cell surface. |
| T1 | 0-92 | Sentence | denotes | Glycan and glycosaminoglycan binding properties of stromal cell-derived factor (SDF)-1alpha. |
| T2 | 93-402 | Sentence | denotes | We show here that cell surface glycosaminoglycans (GAGs) are involved in the binding of stromal cell-derived factor (SDF)-1alpha to CD4(+)lymphoid CEM or monocytic U937 cells, inasmuch as pretreating the cells with heparitinase or chondroitinase inhibits SDF-1alpha binding by 40-41% and 31-35%, respectively. |
| T3 | 403-587 | Sentence | denotes | Soluble heparin or chondroitin sulfate partially but significantly inhibits SDF-1alpha binding to the cells by 45-52% and 42-56%, respectively, while dextran has no significant effect. |
| T4 | 588-682 | Sentence | denotes | Taken together, these results indicate the role of GAGs in SDF-1alpha attachment to the cells. |
| T5 | 683-919 | Sentence | denotes | However, the effects of heparitinase and chondroitinase as well as those of heparin and chondroitin sulfate are not additive, which suggests that SDF-1alpha may attach to the cells through different GAGs, and also through other ligands. |
| T6 | 920-991 | Sentence | denotes | Soluble mannan also inhibits SDF-1alpha binding to the cells by 30-33%. |
| T7 | 992-1078 | Sentence | denotes | Additivity between this effect and that of heparin or chondroitin sulfate is observed. |
| T8 | 1079-1189 | Sentence | denotes | Therefore, beside GAGs, mannose-containing species may also be involved in SDF-1alpha attachment to the cells. |
| T9 | 1190-1408 | Sentence | denotes | Accordingly, SDF-1alpha specifically binds to heparin-agarose and mannose-divinylsulfone agarose affinity matrices, and these interactions are inhibited respectively by soluble heparin, chondroitin sulfate, and mannan. |
| T10 | 1409-1596 | Sentence | denotes | We have previously shown that gp120 of X4 strain HIV-1LAI presents specific carbohydrate-binding properties for mannosylated derivatives, including mannan, and for GAGs including heparin. |
| T11 | 1597-1738 | Sentence | denotes | The present data therefore indicate that, in the same manner as HIV-1 Env, SDF-1alpha can interact with GAGs and glycans at the cell surface. |
| T1 | 0-92 | Sentence | denotes | Glycan and glycosaminoglycan binding properties of stromal cell-derived factor (SDF)-1alpha. |
| T2 | 93-402 | Sentence | denotes | We show here that cell surface glycosaminoglycans (GAGs) are involved in the binding of stromal cell-derived factor (SDF)-1alpha to CD4(+)lymphoid CEM or monocytic U937 cells, inasmuch as pretreating the cells with heparitinase or chondroitinase inhibits SDF-1alpha binding by 40-41% and 31-35%, respectively. |
| T3 | 403-587 | Sentence | denotes | Soluble heparin or chondroitin sulfate partially but significantly inhibits SDF-1alpha binding to the cells by 45-52% and 42-56%, respectively, while dextran has no significant effect. |
| T4 | 588-682 | Sentence | denotes | Taken together, these results indicate the role of GAGs in SDF-1alpha attachment to the cells. |
| T5 | 683-919 | Sentence | denotes | However, the effects of heparitinase and chondroitinase as well as those of heparin and chondroitin sulfate are not additive, which suggests that SDF-1alpha may attach to the cells through different GAGs, and also through other ligands. |
| T6 | 920-991 | Sentence | denotes | Soluble mannan also inhibits SDF-1alpha binding to the cells by 30-33%. |
| T7 | 992-1078 | Sentence | denotes | Additivity between this effect and that of heparin or chondroitin sulfate is observed. |
| T8 | 1079-1189 | Sentence | denotes | Therefore, beside GAGs, mannose-containing species may also be involved in SDF-1alpha attachment to the cells. |
| T9 | 1190-1408 | Sentence | denotes | Accordingly, SDF-1alpha specifically binds to heparin-agarose and mannose-divinylsulfone agarose affinity matrices, and these interactions are inhibited respectively by soluble heparin, chondroitin sulfate, and mannan. |
| T10 | 1409-1596 | Sentence | denotes | We have previously shown that gp120 of X4 strain HIV-1LAI presents specific carbohydrate-binding properties for mannosylated derivatives, including mannan, and for GAGs including heparin. |
| T11 | 1597-1738 | Sentence | denotes | The present data therefore indicate that, in the same manner as HIV-1 Env, SDF-1alpha can interact with GAGs and glycans at the cell surface. |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 324-338 | http://purl.obolibrary.org/obo/GO_0043890 | denotes | chondroitinase |
| T2 | 724-738 | http://purl.obolibrary.org/obo/GO_0043890 | denotes | chondroitinase |
| T3 | 434-441 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulfate |
| T4 | 783-790 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulfate |
| T5 | 1058-1065 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulfate |
| T6 | 1388-1395 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulfate |
| T7 | 1521-1533 | http://purl.obolibrary.org/obo/GO_0097502 | denotes | mannosylated |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 11-36 | http://purl.obolibrary.org/obo/GO_0005539 | denotes | glycosaminoglycan binding |
| T2 | 29-36 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T3 | 170-177 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T4 | 359-366 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T5 | 490-497 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T6 | 960-967 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binding |
| T7 | 1227-1232 | http://purl.obolibrary.org/obo/GO_0070026 | denotes | binds |
| T8 | 29-36 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T9 | 170-177 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T10 | 359-366 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T11 | 490-497 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T12 | 960-967 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binding |
| T13 | 1227-1232 | http://purl.obolibrary.org/obo/GO_0003680 | denotes | binds |
| T14 | 29-36 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T15 | 170-177 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T16 | 359-366 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T17 | 490-497 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T18 | 960-967 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binding |
| T19 | 1227-1232 | http://purl.obolibrary.org/obo/GO_0017091 | denotes | binds |
| T20 | 29-36 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T21 | 170-177 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T22 | 359-366 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T23 | 490-497 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T24 | 960-967 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
| T25 | 1227-1232 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binds |
| T26 | 911-918 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | ligands |
| T27 | 1227-1243 | http://purl.obolibrary.org/obo/GO_0008201 | denotes | binds to heparin |
| T28 | 1485-1505 | http://purl.obolibrary.org/obo/GO_0030246 | denotes | carbohydrate-binding |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 59-63 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T2 | 111-115 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3 | 189-193 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T4 | 262-267 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T5 | 297-302 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T6 | 505-510 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T7 | 676-681 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T8 | 858-863 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T9 | 975-980 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T10 | 1183-1188 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T11 | 111-123 | http://purl.obolibrary.org/obo/GO_0009986 | denotes | cell surface |
| T12 | 1725-1737 | http://purl.obolibrary.org/obo/GO_0009986 | denotes | cell surface |
GlycoBiology-Motifs
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 411-418 | http://rdf.glycoinfo.org/glycan/G54161DR | denotes | heparin |
| T2 | 759-766 | http://rdf.glycoinfo.org/glycan/G54161DR | denotes | heparin |
| T3 | 1035-1042 | http://rdf.glycoinfo.org/glycan/G54161DR | denotes | heparin |
| T4 | 1236-1243 | http://rdf.glycoinfo.org/glycan/G54161DR | denotes | heparin |
| T5 | 1367-1374 | http://rdf.glycoinfo.org/glycan/G54161DR | denotes | heparin |
| T6 | 1588-1595 | http://rdf.glycoinfo.org/glycan/G54161DR | denotes | heparin |
| T7 | 422-433 | http://rdf.glycoinfo.org/glycan/G00018MO | denotes | chondroitin |
| T8 | 771-782 | http://rdf.glycoinfo.org/glycan/G00018MO | denotes | chondroitin |
| T9 | 1046-1057 | http://rdf.glycoinfo.org/glycan/G00018MO | denotes | chondroitin |
| T10 | 1376-1387 | http://rdf.glycoinfo.org/glycan/G00018MO | denotes | chondroitin |
| T11 | 422-441 | http://rdf.glycoinfo.org/glycan/G00018MO | denotes | chondroitin sulfate |
| T12 | 771-790 | http://rdf.glycoinfo.org/glycan/G00018MO | denotes | chondroitin sulfate |
| T13 | 1046-1065 | http://rdf.glycoinfo.org/glycan/G00018MO | denotes | chondroitin sulfate |
| T14 | 1376-1395 | http://rdf.glycoinfo.org/glycan/G00018MO | denotes | chondroitin sulfate |
GlycoBiology-Epitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoEpitope-B_T1 | 422-433 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| PD-GlycoEpitope-B_T2 | 771-782 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| PD-GlycoEpitope-B_T3 | 1046-1057 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| PD-GlycoEpitope-B_T4 | 1376-1387 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| PD-GlycoEpitope-B_T5 | 517-519 | http://www.glycoepitope.jp/epitopes/AN0785 | denotes | 52 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 422-433 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T2 | 771-782 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T3 | 1046-1057 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T4 | 1376-1387 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 422-433 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T2 | 771-782 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T3 | 1046-1057 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T4 | 1376-1387 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 422-433 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T2 | 771-782 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T3 | 1046-1057 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T4 | 1376-1387 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 51-63 | Cell | denotes | stromal cell | http://purl.obolibrary.org/obo/CL:0000499 |
| T2 | 181-193 | Cell | denotes | stromal cell | http://purl.obolibrary.org/obo/CL:0000499 |
| T3 | 247-256 | Cell | denotes | monocytic | http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054 |
| T5 | 658-681 | Cell | denotes | attachment to the cells | http://purl.obolibrary.org/obo/CL:0000386 |
| T6 | 1165-1188 | Cell | denotes | attachment to the cells | http://purl.obolibrary.org/obo/CL:0000386 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 51-63 | Body_part | denotes | stromal cell | http://purl.obolibrary.org/obo/CL_0000499 |
| T2 | 181-193 | Body_part | denotes | stromal cell | http://purl.obolibrary.org/obo/CL_0000499 |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 422-433 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T2 | 771-782 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T3 | 1046-1057 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T4 | 1376-1387 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-92 | Sentence | denotes | Glycan and glycosaminoglycan binding properties of stromal cell-derived factor (SDF)-1alpha. |
| T2 | 93-402 | Sentence | denotes | We show here that cell surface glycosaminoglycans (GAGs) are involved in the binding of stromal cell-derived factor (SDF)-1alpha to CD4(+)lymphoid CEM or monocytic U937 cells, inasmuch as pretreating the cells with heparitinase or chondroitinase inhibits SDF-1alpha binding by 40-41% and 31-35%, respectively. |
| T3 | 403-587 | Sentence | denotes | Soluble heparin or chondroitin sulfate partially but significantly inhibits SDF-1alpha binding to the cells by 45-52% and 42-56%, respectively, while dextran has no significant effect. |
| T4 | 588-682 | Sentence | denotes | Taken together, these results indicate the role of GAGs in SDF-1alpha attachment to the cells. |
| T5 | 683-919 | Sentence | denotes | However, the effects of heparitinase and chondroitinase as well as those of heparin and chondroitin sulfate are not additive, which suggests that SDF-1alpha may attach to the cells through different GAGs, and also through other ligands. |
| T6 | 920-991 | Sentence | denotes | Soluble mannan also inhibits SDF-1alpha binding to the cells by 30-33%. |
| T7 | 992-1078 | Sentence | denotes | Additivity between this effect and that of heparin or chondroitin sulfate is observed. |
| T8 | 1079-1189 | Sentence | denotes | Therefore, beside GAGs, mannose-containing species may also be involved in SDF-1alpha attachment to the cells. |
| T9 | 1190-1408 | Sentence | denotes | Accordingly, SDF-1alpha specifically binds to heparin-agarose and mannose-divinylsulfone agarose affinity matrices, and these interactions are inhibited respectively by soluble heparin, chondroitin sulfate, and mannan. |
| T10 | 1409-1596 | Sentence | denotes | We have previously shown that gp120 of X4 strain HIV-1LAI presents specific carbohydrate-binding properties for mannosylated derivatives, including mannan, and for GAGs including heparin. |
| T11 | 1597-1738 | Sentence | denotes | The present data therefore indicate that, in the same manner as HIV-1 Env, SDF-1alpha can interact with GAGs and glycans at the cell surface. |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 111-123 | Body_part | denotes | cell surface | FMA:67653 |
| T2 | 247-256 | Body_part | denotes | monocytic | FMA:62864 |
| T3 | 1458-1461 | Body_part | denotes | HIV | FMA:278683 |
| T4 | 1661-1664 | Body_part | denotes | HIV | FMA:278683 |
| T5 | 1725-1737 | Body_part | denotes | cell surface | FMA:67653 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 51-63 | Body_part | denotes | stromal cell | http://purl.obolibrary.org/obo/CL_0000499 |
| T2 | 181-193 | Body_part | denotes | stromal cell | http://purl.obolibrary.org/obo/CL_0000499 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 51-63 | Cell | denotes | stromal cell | http://purl.obolibrary.org/obo/CL:0000499 |
| T2 | 181-193 | Cell | denotes | stromal cell | http://purl.obolibrary.org/obo/CL:0000499 |
| T3 | 247-256 | Cell | denotes | monocytic | http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054 |
| T5 | 658-681 | Cell | denotes | attachment to the cells | http://purl.obolibrary.org/obo/CL:0000386 |
| T6 | 1165-1188 | Cell | denotes | attachment to the cells | http://purl.obolibrary.org/obo/CL:0000386 |