PubMed:10477716 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/10477716","sourcedb":"PubMed","sourceid":"10477716","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/10477716","text":"Nuclear factor-kappaB-dependent induction of interleukin-8 gene expression by tumor necrosis factor alpha: evidence for an antioxidant sensitive activating pathway distinct from nuclear translocation.\nTumor necrosis factor alpha (TNFalpha) is a pluripotent activator of inflammation by inducing a proinflammatory cytokine cascade. This phenomenon is mediated, in part, through inducible expression of the CXC chemokine, interleukin-8 (IL-8). In this study, we investigate the role of TNFalpha-inducible reactive oxygen species (ROS) in IL-8 expression by \"monocyte-like\" U937 histiocytic lymphoma cells. TNFalpha is a rapid activator of IL-8 gene expression by U937, producing a 50-fold induction of mRNA within 1 hour of treatment. In gene transfection assays, the effect of TNFalpha requires the presence of an inducible nuclear factor-kappaB (NF-kappaB) (Rel A) binding site in the IL-8 promoter. TNFalpha treatment induces a rapid translocation of the 65 kD transcriptional activator NF-kappaB subunit, Rel A, whose binding in the nucleus occurs before changes in intracellular ROS. Pretreatment (or up to 15 minutes posttreatment) relative to TNFalpha with the antioxidant dimethyl sulfoxide (DMSO) (2% [vol/vol]) blocks 80% of NF-kappaB-dependent transcription. Surprisingly, however, DMSO has no effect on inducible Rel A binding. Similar selective effects on NF-kappaB transcription are seen with the unrelated antioxidants, N-acetylcysteine (NAC) and vitamin C. These data indicate that TNFalpha induces a delayed ROS-dependent signalling pathway that is required for NF-kappaB transcriptional activation and is separable from that required for its nuclear translocation. Further definition of this pathway will yield new insights into inflammation initiated by TNFalpha signalling.","tracks":[{"project":"genia-medco-coref","denotations":[{"id":"C1","span":{"begin":45,"end":74},"obj":"NP"},{"id":"C2","span":{"begin":78,"end":105},"obj":"NP"},{"id":"C3","span":{"begin":201,"end":239},"obj":"NP"},{"id":"C4","span":{"begin":401,"end":418},"obj":"NP"},{"id":"C5","span":{"begin":420,"end":440},"obj":"NP"},{"id":"C6","span":{"begin":536,"end":551},"obj":"NP"},{"id":"C7","span":{"begin":555,"end":602},"obj":"NP"},{"id":"C8","span":{"begin":604,"end":612},"obj":"NP"},{"id":"C9","span":{"begin":637,"end":657},"obj":"NP"},{"id":"C10","span":{"begin":661,"end":665},"obj":"NP"},{"id":"C11","span":{"begin":776,"end":784},"obj":"NP"},{"id":"C12","span":{"begin":952,"end":1005},"obj":"NP"},{"id":"C13","span":{"begin":1007,"end":1012},"obj":"NP"},{"id":"C14","span":{"begin":1014,"end":1019},"obj":"NP"},{"id":"C15","span":{"begin":1148,"end":1156},"obj":"NP"},{"id":"C16","span":{"begin":1162,"end":1203},"obj":"NP"},{"id":"C17","span":{"begin":1291,"end":1295},"obj":"NP"},{"id":"C18","span":{"begin":1405,"end":1431},"obj":"NP"},{"id":"C19","span":{"begin":1433,"end":1469},"obj":"NP"},{"id":"C20","span":{"begin":1496,"end":1504},"obj":"NP"},{"id":"C22","span":{"begin":1513,"end":1555},"obj":"NP"},{"id":"C23","span":{"begin":1556,"end":1560},"obj":"NP"},{"id":"C24","span":{"begin":1636,"end":1640},"obj":"NP"},{"id":"C21","span":{"begin":1513,"end":1679},"obj":"NP"},{"id":"C25","span":{"begin":1703,"end":1715},"obj":"NP"}],"relations":[{"id":"R1","pred":"coref-ident","subj":"C3","obj":"C2"},{"id":"R2","pred":"coref-appos","subj":"C5","obj":"C4"},{"id":"R3","pred":"coref-ident","subj":"C6","obj":"C1"},{"id":"R4","pred":"coref-ident","subj":"C8","obj":"C3"},{"id":"R5","pred":"coref-ident","subj":"C9","obj":"C6"},{"id":"R6","pred":"coref-ident","subj":"C10","obj":"C7"},{"id":"R7","pred":"coref-ident","subj":"C11","obj":"C8"},{"id":"R8","pred":"coref-appos","subj":"C13","obj":"C12"},{"id":"R9","pred":"coref-relat","subj":"C14","obj":"C12"},{"id":"R10","pred":"coref-ident","subj":"C15","obj":"C11"},{"id":"R11","pred":"coref-ident","subj":"C17","obj":"C16"},{"id":"R12","pred":"coref-appos","subj":"C19","obj":"C18"},{"id":"R13","pred":"coref-ident","subj":"C20","obj":"C15"},{"id":"R14","pred":"coref-relat","subj":"C23","obj":"C22"},{"id":"R15","pred":"coref-pron","subj":"C24","obj":"C22"},{"id":"R16","pred":"coref-ident","subj":"C25","obj":"C21"}],"attributes":[{"subj":"C1","pred":"source","obj":"genia-medco-coref"},{"subj":"C2","pred":"source","obj":"genia-medco-coref"},{"subj":"C3","pred":"source","obj":"genia-medco-coref"},{"subj":"C4","pred":"source","obj":"genia-medco-coref"},{"subj":"C5","pred":"source","obj":"genia-medco-coref"},{"subj":"C6","pred":"source","obj":"genia-medco-coref"},{"subj":"C7","pred":"source","obj":"genia-medco-coref"},{"subj":"C8","pred":"source","obj":"genia-medco-coref"},{"subj":"C9","pred":"source","obj":"genia-medco-coref"},{"subj":"C10","pred":"source","obj":"genia-medco-coref"},{"subj":"C11","pred":"source","obj":"genia-medco-coref"},{"subj":"C12","pred":"source","obj":"genia-medco-coref"},{"subj":"C13","pred":"source","obj":"genia-medco-coref"},{"subj":"C14","pred":"source","obj":"genia-medco-coref"},{"subj":"C15","pred":"source","obj":"genia-medco-coref"},{"subj":"C16","pred":"source","obj":"genia-medco-coref"},{"subj":"C17","pred":"source","obj":"genia-medco-coref"},{"subj":"C18","pred":"source","obj":"genia-medco-coref"},{"subj":"C19","pred":"source","obj":"genia-medco-coref"},{"subj":"C20","pred":"source","obj":"genia-medco-coref"},{"subj":"C22","pred":"source","obj":"genia-medco-coref"},{"subj":"C23","pred":"source","obj":"genia-medco-coref"},{"subj":"C24","pred":"source","obj":"genia-medco-coref"},{"subj":"C21","pred":"source","obj":"genia-medco-coref"},{"subj":"C25","pred":"source","obj":"genia-medco-coref"}]},{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":201,"end":206},"obj":"HP_0002664"},{"id":"T2","span":{"begin":588,"end":596},"obj":"HP_0002665"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"}]},{"project":"jnlpba-st-training","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"protein"},{"id":"T2","span":{"begin":45,"end":58},"obj":"protein"},{"id":"T3","span":{"begin":78,"end":105},"obj":"protein"},{"id":"T4","span":{"begin":201,"end":228},"obj":"protein"},{"id":"T5","span":{"begin":230,"end":238},"obj":"protein"},{"id":"T6","span":{"begin":297,"end":321},"obj":"protein"},{"id":"T7","span":{"begin":405,"end":418},"obj":"protein"},{"id":"T8","span":{"begin":420,"end":433},"obj":"protein"},{"id":"T9","span":{"begin":484,"end":492},"obj":"protein"},{"id":"T10","span":{"begin":536,"end":540},"obj":"protein"},{"id":"T11","span":{"begin":571,"end":602},"obj":"cell_line"},{"id":"T12","span":{"begin":604,"end":612},"obj":"protein"},{"id":"T13","span":{"begin":637,"end":646},"obj":"DNA"},{"id":"T14","span":{"begin":661,"end":665},"obj":"cell_line"},{"id":"T15","span":{"begin":700,"end":704},"obj":"RNA"},{"id":"T16","span":{"begin":776,"end":784},"obj":"protein"},{"id":"T17","span":{"begin":813,"end":877},"obj":"DNA"},{"id":"T18","span":{"begin":885,"end":898},"obj":"DNA"},{"id":"T19","span":{"begin":900,"end":908},"obj":"protein"},{"id":"T20","span":{"begin":956,"end":987},"obj":"protein"},{"id":"T21","span":{"begin":988,"end":1005},"obj":"protein"},{"id":"T22","span":{"begin":1007,"end":1012},"obj":"protein"},{"id":"T23","span":{"begin":1148,"end":1156},"obj":"protein"},{"id":"T24","span":{"begin":1233,"end":1242},"obj":"protein"},{"id":"T25","span":{"begin":1323,"end":1328},"obj":"protein"},{"id":"T26","span":{"begin":1367,"end":1376},"obj":"protein"},{"id":"T27","span":{"begin":1496,"end":1504},"obj":"protein"},{"id":"T28","span":{"begin":1577,"end":1586},"obj":"protein"},{"id":"T29","span":{"begin":1771,"end":1779},"obj":"protein"}],"attributes":[{"subj":"T1","pred":"source","obj":"jnlpba-st-training"},{"subj":"T2","pred":"source","obj":"jnlpba-st-training"},{"subj":"T3","pred":"source","obj":"jnlpba-st-training"},{"subj":"T4","pred":"source","obj":"jnlpba-st-training"},{"subj":"T5","pred":"source","obj":"jnlpba-st-training"},{"subj":"T6","pred":"source","obj":"jnlpba-st-training"},{"subj":"T7","pred":"source","obj":"jnlpba-st-training"},{"subj":"T8","pred":"source","obj":"jnlpba-st-training"},{"subj":"T9","pred":"source","obj":"jnlpba-st-training"},{"subj":"T10","pred":"source","obj":"jnlpba-st-training"},{"subj":"T11","pred":"source","obj":"jnlpba-st-training"},{"subj":"T12","pred":"source","obj":"jnlpba-st-training"},{"subj":"T13","pred":"source","obj":"jnlpba-st-training"},{"subj":"T14","pred":"source","obj":"jnlpba-st-training"},{"subj":"T15","pred":"source","obj":"jnlpba-st-training"},{"subj":"T16","pred":"source","obj":"jnlpba-st-training"},{"subj":"T17","pred":"source","obj":"jnlpba-st-training"},{"subj":"T18","pred":"source","obj":"jnlpba-st-training"},{"subj":"T19","pred":"source","obj":"jnlpba-st-training"},{"subj":"T20","pred":"source","obj":"jnlpba-st-training"},{"subj":"T21","pred":"source","obj":"jnlpba-st-training"},{"subj":"T22","pred":"source","obj":"jnlpba-st-training"},{"subj":"T23","pred":"source","obj":"jnlpba-st-training"},{"subj":"T24","pred":"source","obj":"jnlpba-st-training"},{"subj":"T25","pred":"source","obj":"jnlpba-st-training"},{"subj":"T26","pred":"source","obj":"jnlpba-st-training"},{"subj":"T27","pred":"source","obj":"jnlpba-st-training"},{"subj":"T28","pred":"source","obj":"jnlpba-st-training"},{"subj":"T29","pred":"source","obj":"jnlpba-st-training"}]},{"project":"pubmed-sentences-benchmark","denotations":[{"id":"S1","span":{"begin":0,"end":200},"obj":"Sentence"},{"id":"S2","span":{"begin":201,"end":330},"obj":"Sentence"},{"id":"S3","span":{"begin":331,"end":441},"obj":"Sentence"},{"id":"S4","span":{"begin":442,"end":603},"obj":"Sentence"},{"id":"S5","span":{"begin":604,"end":732},"obj":"Sentence"},{"id":"S6","span":{"begin":733,"end":899},"obj":"Sentence"},{"id":"S7","span":{"begin":900,"end":1086},"obj":"Sentence"},{"id":"S8","span":{"begin":1087,"end":1267},"obj":"Sentence"},{"id":"S9","span":{"begin":1268,"end":1337},"obj":"Sentence"},{"id":"S10","span":{"begin":1338,"end":1470},"obj":"Sentence"},{"id":"S11","span":{"begin":1471,"end":1680},"obj":"Sentence"},{"id":"S12","span":{"begin":1681,"end":1791},"obj":"Sentence"}],"attributes":[{"subj":"S1","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S2","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S3","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S4","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S5","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S6","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S7","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S8","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S9","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S10","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S11","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S12","pred":"source","obj":"pubmed-sentences-benchmark"}]},{"project":"GENIAcorpus","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"protein_complex"},{"id":"T2","span":{"begin":45,"end":58},"obj":"protein_molecule"},{"id":"T3","span":{"begin":78,"end":105},"obj":"protein_molecule"},{"id":"T4","span":{"begin":178,"end":199},"obj":"other_name"},{"id":"T5","span":{"begin":201,"end":228},"obj":"protein_molecule"},{"id":"T6","span":{"begin":230,"end":238},"obj":"protein_molecule"},{"id":"T7","span":{"begin":245,"end":282},"obj":"other_name"},{"id":"T8","span":{"begin":297,"end":321},"obj":"protein_family_or_group"},{"id":"T9","span":{"begin":405,"end":418},"obj":"protein_family_or_group"},{"id":"T10","span":{"begin":420,"end":433},"obj":"protein_molecule"},{"id":"T11","span":{"begin":484,"end":492},"obj":"protein_molecule"},{"id":"T12","span":{"begin":536,"end":540},"obj":"protein_molecule"},{"id":"T13","span":{"begin":571,"end":602},"obj":"cell_line"},{"id":"T14","span":{"begin":604,"end":612},"obj":"protein_molecule"},{"id":"T15","span":{"begin":637,"end":641},"obj":"protein_molecule"},{"id":"T16","span":{"begin":661,"end":665},"obj":"cell_line"},{"id":"T17","span":{"begin":700,"end":704},"obj":"RNA_family_or_group"},{"id":"T18","span":{"begin":776,"end":784},"obj":"protein_molecule"},{"id":"T19","span":{"begin":813,"end":846},"obj":"DNA_domain_or_region"},{"id":"T20","span":{"begin":846,"end":855},"obj":"protein_complex"},{"id":"T21","span":{"begin":858,"end":863},"obj":"protein_subunit"},{"id":"T22","span":{"begin":885,"end":889},"obj":"protein_molecule"},{"id":"T23","span":{"begin":900,"end":908},"obj":"protein_molecule"},{"id":"T24","span":{"begin":956,"end":987},"obj":"protein_molecule"},{"id":"T25","span":{"begin":988,"end":997},"obj":"protein_complex"},{"id":"T26","span":{"begin":1007,"end":1012},"obj":"protein_subunit"},{"id":"T27","span":{"begin":1035,"end":1042},"obj":"cell_component"},{"id":"T28","span":{"begin":1068,"end":1085},"obj":"other_name"},{"id":"T29","span":{"begin":1148,"end":1156},"obj":"protein_molecule"},{"id":"T30","span":{"begin":1166,"end":1177},"obj":"other_organic_compound"},{"id":"T31","span":{"begin":1178,"end":1196},"obj":"other_organic_compound"},{"id":"T32","span":{"begin":1198,"end":1202},"obj":"other_organic_compound"},{"id":"T33","span":{"begin":1233,"end":1242},"obj":"protein_complex"},{"id":"T34","span":{"begin":1291,"end":1295},"obj":"other_organic_compound"},{"id":"T35","span":{"begin":1323,"end":1328},"obj":"protein_subunit"},{"id":"T36","span":{"begin":1367,"end":1376},"obj":"protein_complex"},{"id":"T37","span":{"begin":1433,"end":1449},"obj":"amino_acid_monomer"},{"id":"T38","span":{"begin":1451,"end":1454},"obj":"amino_acid_monomer"},{"id":"T39","span":{"begin":1460,"end":1469},"obj":"other_organic_compound"},{"id":"T40","span":{"begin":1496,"end":1504},"obj":"protein_molecule"},{"id":"T41","span":{"begin":1523,"end":1555},"obj":"other_name"},{"id":"T42","span":{"begin":1577,"end":1586},"obj":"protein_complex"},{"id":"T43","span":{"begin":1658,"end":1679},"obj":"other_name"},{"id":"T44","span":{"begin":1745,"end":1757},"obj":"other_name"},{"id":"T45","span":{"begin":1771,"end":1779},"obj":"protein_molecule"}],"attributes":[{"subj":"T1","pred":"source","obj":"GENIAcorpus"},{"subj":"T2","pred":"source","obj":"GENIAcorpus"},{"subj":"T3","pred":"source","obj":"GENIAcorpus"},{"subj":"T4","pred":"source","obj":"GENIAcorpus"},{"subj":"T5","pred":"source","obj":"GENIAcorpus"},{"subj":"T6","pred":"source","obj":"GENIAcorpus"},{"subj":"T7","pred":"source","obj":"GENIAcorpus"},{"subj":"T8","pred":"source","obj":"GENIAcorpus"},{"subj":"T9","pred":"source","obj":"GENIAcorpus"},{"subj":"T10","pred":"source","obj":"GENIAcorpus"},{"subj":"T11","pred":"source","obj":"GENIAcorpus"},{"subj":"T12","pred":"source","obj":"GENIAcorpus"},{"subj":"T13","pred":"source","obj":"GENIAcorpus"},{"subj":"T14","pred":"source","obj":"GENIAcorpus"},{"subj":"T15","pred":"source","obj":"GENIAcorpus"},{"subj":"T16","pred":"source","obj":"GENIAcorpus"},{"subj":"T17","pred":"source","obj":"GENIAcorpus"},{"subj":"T18","pred":"source","obj":"GENIAcorpus"},{"subj":"T19","pred":"source","obj":"GENIAcorpus"},{"subj":"T20","pred":"source","obj":"GENIAcorpus"},{"subj":"T21","pred":"source","obj":"GENIAcorpus"},{"subj":"T22","pred":"source","obj":"GENIAcorpus"},{"subj":"T23","pred":"source","obj":"GENIAcorpus"},{"subj":"T24","pred":"source","obj":"GENIAcorpus"},{"subj":"T25","pred":"source","obj":"GENIAcorpus"},{"subj":"T26","pred":"source","obj":"GENIAcorpus"},{"subj":"T27","pred":"source","obj":"GENIAcorpus"},{"subj":"T28","pred":"source","obj":"GENIAcorpus"},{"subj":"T29","pred":"source","obj":"GENIAcorpus"},{"subj":"T30","pred":"source","obj":"GENIAcorpus"},{"subj":"T31","pred":"source","obj":"GENIAcorpus"},{"subj":"T32","pred":"source","obj":"GENIAcorpus"},{"subj":"T33","pred":"source","obj":"GENIAcorpus"},{"subj":"T34","pred":"source","obj":"GENIAcorpus"},{"subj":"T35","pred":"source","obj":"GENIAcorpus"},{"subj":"T36","pred":"source","obj":"GENIAcorpus"},{"subj":"T37","pred":"source","obj":"GENIAcorpus"},{"subj":"T38","pred":"source","obj":"GENIAcorpus"},{"subj":"T39","pred":"source","obj":"GENIAcorpus"},{"subj":"T40","pred":"source","obj":"GENIAcorpus"},{"subj":"T41","pred":"source","obj":"GENIAcorpus"},{"subj":"T42","pred":"source","obj":"GENIAcorpus"},{"subj":"T43","pred":"source","obj":"GENIAcorpus"},{"subj":"T44","pred":"source","obj":"GENIAcorpus"},{"subj":"T45","pred":"source","obj":"GENIAcorpus"}]},{"project":"Inflammaging","denotations":[{"id":"T1","span":{"begin":0,"end":200},"obj":"Sentence"},{"id":"T2","span":{"begin":201,"end":330},"obj":"Sentence"},{"id":"T3","span":{"begin":331,"end":441},"obj":"Sentence"},{"id":"T4","span":{"begin":442,"end":603},"obj":"Sentence"},{"id":"T5","span":{"begin":604,"end":732},"obj":"Sentence"},{"id":"T6","span":{"begin":733,"end":899},"obj":"Sentence"},{"id":"T7","span":{"begin":900,"end":1086},"obj":"Sentence"},{"id":"T8","span":{"begin":1087,"end":1267},"obj":"Sentence"},{"id":"T9","span":{"begin":1268,"end":1337},"obj":"Sentence"},{"id":"T10","span":{"begin":1338,"end":1470},"obj":"Sentence"},{"id":"T11","span":{"begin":1471,"end":1680},"obj":"Sentence"},{"id":"T12","span":{"begin":1681,"end":1791},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":200},"obj":"Sentence"},{"id":"T2","span":{"begin":201,"end":330},"obj":"Sentence"},{"id":"T3","span":{"begin":331,"end":441},"obj":"Sentence"},{"id":"T4","span":{"begin":442,"end":603},"obj":"Sentence"},{"id":"T5","span":{"begin":604,"end":732},"obj":"Sentence"},{"id":"T6","span":{"begin":733,"end":899},"obj":"Sentence"},{"id":"T7","span":{"begin":900,"end":1086},"obj":"Sentence"},{"id":"T8","span":{"begin":1087,"end":1267},"obj":"Sentence"},{"id":"T9","span":{"begin":1268,"end":1337},"obj":"Sentence"},{"id":"T10","span":{"begin":1338,"end":1470},"obj":"Sentence"},{"id":"T11","span":{"begin":1471,"end":1680},"obj":"Sentence"},{"id":"T12","span":{"begin":1681,"end":1791},"obj":"Sentence"}],"attributes":[{"subj":"T1","pred":"source","obj":"Inflammaging"},{"subj":"T2","pred":"source","obj":"Inflammaging"},{"subj":"T3","pred":"source","obj":"Inflammaging"},{"subj":"T4","pred":"source","obj":"Inflammaging"},{"subj":"T5","pred":"source","obj":"Inflammaging"},{"subj":"T6","pred":"source","obj":"Inflammaging"},{"subj":"T7","pred":"source","obj":"Inflammaging"},{"subj":"T8","pred":"source","obj":"Inflammaging"},{"subj":"T9","pred":"source","obj":"Inflammaging"},{"subj":"T10","pred":"source","obj":"Inflammaging"},{"subj":"T11","pred":"source","obj":"Inflammaging"},{"subj":"T12","pred":"source","obj":"Inflammaging"},{"subj":"T1","pred":"source","obj":"Inflammaging"},{"subj":"T2","pred":"source","obj":"Inflammaging"},{"subj":"T3","pred":"source","obj":"Inflammaging"},{"subj":"T4","pred":"source","obj":"Inflammaging"},{"subj":"T5","pred":"source","obj":"Inflammaging"},{"subj":"T6","pred":"source","obj":"Inflammaging"},{"subj":"T7","pred":"source","obj":"Inflammaging"},{"subj":"T8","pred":"source","obj":"Inflammaging"},{"subj":"T9","pred":"source","obj":"Inflammaging"},{"subj":"T10","pred":"source","obj":"Inflammaging"},{"subj":"T11","pred":"source","obj":"Inflammaging"},{"subj":"T12","pred":"source","obj":"Inflammaging"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"genia-medco-coref","color":"#bf93ec","default":true},{"id":"PubmedHPO","color":"#93eca5"},{"id":"jnlpba-st-training","color":"#ec939b"},{"id":"pubmed-sentences-benchmark","color":"#93b5ec"},{"id":"GENIAcorpus","color":"#cfec93"},{"id":"Inflammaging","color":"#ec93e9"}]}]}}