PubMed:10449776
Annnotations
PMID_GLOBAL
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 28-50 | DiseaseOrPhenotypicFeature | denotes | AIDS-related lymphomas | 0018842 |
| T2 | 73-77 | DiseaseOrPhenotypicFeature | denotes | AIDS | 0012268 |
| T3 | 86-108 | DiseaseOrPhenotypicFeature | denotes | non-Hodgkin's lymphoma | 0018908 |
| T4 | 110-114 | DiseaseOrPhenotypicFeature | denotes | AIDS | 0012268 |
| T5 | 115-118 | DiseaseOrPhenotypicFeature | denotes | NHL | 0018908 |
| T6 | 212-216 | DiseaseOrPhenotypicFeature | denotes | AIDS | 0012268 |
| T7 | 217-220 | DiseaseOrPhenotypicFeature | denotes | NHL | 0018908 |
| T8 | 269-274 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
| T9 | 379-383 | DiseaseOrPhenotypicFeature | denotes | AIDS | 0012268 |
| T10 | 384-387 | DiseaseOrPhenotypicFeature | denotes | NHL | 0018908 |
| T11 | 399-421 | DiseaseOrPhenotypicFeature | denotes | immunoblastic lymphoma | 0022037 |
| T12 | 436-440 | DiseaseOrPhenotypicFeature | denotes | AIDS | 0012268 |
| T13 | 535-539 | DiseaseOrPhenotypicFeature | denotes | AIDS | 0012268 |
| T14 | 619-623 | DiseaseOrPhenotypicFeature | denotes | AIDS | 0012268 |
| T15 | 678-693 | DiseaseOrPhenotypicFeature | denotes | T cell leukemia | 0005525 |
| T16 | 694-702 | DiseaseOrPhenotypicFeature | denotes | lymphoma | 0003659|0003660|0005062 |
| T19 | 781-786 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
| T20 | 844-848 | DiseaseOrPhenotypicFeature | denotes | AIDS | 0012268 |
| T21 | 849-852 | DiseaseOrPhenotypicFeature | denotes | NHL | 0018908 |
| T22 | 904-908 | DiseaseOrPhenotypicFeature | denotes | AIDS | 0012268 |
| T23 | 972-977 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
| T24 | 987-991 | DiseaseOrPhenotypicFeature | denotes | AIDS | 0012268 |
| T25 | 1056-1068 | DiseaseOrPhenotypicFeature | denotes | Hyperplastic | 0005043 |
| T26 | 1385-1389 | DiseaseOrPhenotypicFeature | denotes | AIDS | 0012268 |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 86-108 | HP_0012539 | denotes | non-Hodgkin's lymphoma |
| T2 | 90-108 | HP_0012189 | denotes | Hodgkin's lymphoma |
| T3 | 100-108 | HP_0002665 | denotes | lymphoma |
| T4 | 185-191 | HP_0002664 | denotes | tumors |
| T5 | 269-274 | HP_0002664 | denotes | tumor |
| T6 | 413-421 | HP_0002665 | denotes | lymphoma |
| T7 | 678-702 | HP_0005517 | denotes | T cell leukemia/lymphoma |
| T8 | 685-693 | HP_0001909 | denotes | leukemia |
| T9 | 694-702 | HP_0002665 | denotes | lymphoma |
| T10 | 781-786 | HP_0002664 | denotes | tumor |
| T11 | 914-920 | HP_0002664 | denotes | tumors |
| T12 | 972-977 | HP_0002664 | denotes | tumor |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-13 | DNA | denotes | TCL1 oncogene |
| T2 | 256-265 | DNA | denotes | oncogenes |
| T3 | 269-291 | DNA | denotes | tumor-suppressor genes |
| T4 | 507-520 | DNA | denotes | TCL1 oncogene |
| T5 | 535-570 | DNA | denotes | AIDS IBLP-associated cDNA fragments |
| T6 | 639-643 | protein | denotes | TCL1 |
| T7 | 774-792 | cell_line | denotes | B cell tumor lines |
| T8 | 803-807 | protein | denotes | TCL1 |
| T9 | 867-871 | protein | denotes | TCL1 |
| T10 | 931-935 | protein | denotes | TCL1 |
| T11 | 1111-1115 | protein | denotes | TCL1 |
| T12 | 1138-1157 | cell_type | denotes | mantle zone B cells |
| T13 | 1170-1196 | cell_type | denotes | interfollicular zone cells |
| T14 | 1206-1229 | cell_type | denotes | follicle-center B cells |
| T15 | 1231-1243 | cell_type | denotes | centroblasts |
| T16 | 1248-1259 | cell_type | denotes | centrocytes |
| T17 | 1309-1313 | protein | denotes | TCL1 |
| T18 | 1359-1368 | DNA | denotes | oncogenes |
| T19 | 1429-1433 | protein | denotes | TCL1 |
| T20 | 1448-1477 | cell_type | denotes | quiescent mantle zone B cells |
| T21 | 1509-1543 | cell_type | denotes | germinal center follicular B cells |
| T22 | 1591-1596 | protein | denotes | BCL-2 |
| T23 | 1623-1647 | cell_type | denotes | nonproliferating B cells |
| T24 | 1662-1666 | protein | denotes | TCL1 |
| T25 | 1694-1720 | cell_type | denotes | naïve preactivated B cells |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 10449776-0#0#4#gene8115 | 0-4 | gene8115 | denotes | TCL1 |
| 10449776-0#0#4#gene9623 | 0-4 | gene9623 | denotes | TCL1 |
| 10449776-0#28#50#diseaseC0085090 | 28-50 | diseaseC0085090 | denotes | AIDS-related lymphomas |
| 10449776-5#9#13#gene8115 | 639-643 | gene8115 | denotes | TCL1 |
| 10449776-5#9#13#gene9623 | 639-643 | gene9623 | denotes | TCL1 |
| 10449776-5#9#13#gene8115 | 639-643 | gene8115 | denotes | TCL1 |
| 10449776-5#9#13#gene9623 | 639-643 | gene9623 | denotes | TCL1 |
| 10449776-5#48#63#diseaseC0023492 | 678-693 | diseaseC0023492 | denotes | T cell leukemia |
| 10449776-5#64#72#diseaseC0024299 | 694-702 | diseaseC0024299 | denotes | lymphoma |
| 10449776-9#55#59#gene8115 | 1111-1115 | gene8115 | denotes | TCL1 |
| 10449776-9#55#59#gene9623 | 1111-1115 | gene9623 | denotes | TCL1 |
| 10449776-9#0#23#diseaseC0340782 | 1056-1079 | diseaseC0340782 | denotes | Hyperplastic lymph node |
| 0#4#gene811528#50#diseaseC0085090 | 10449776-0#0#4#gene8115 | 10449776-0#28#50#diseaseC0085090 | associated_with | TCL1,AIDS-related lymphomas |
| 0#4#gene962328#50#diseaseC0085090 | 10449776-0#0#4#gene9623 | 10449776-0#28#50#diseaseC0085090 | associated_with | TCL1,AIDS-related lymphomas |
| 9#13#gene811548#63#diseaseC0023492 | 10449776-5#9#13#gene8115 | 10449776-5#48#63#diseaseC0023492 | associated_with | TCL1,T cell leukemia |
| 9#13#gene811564#72#diseaseC0024299 | 10449776-5#9#13#gene8115 | 10449776-5#64#72#diseaseC0024299 | associated_with | TCL1,lymphoma |
| 9#13#gene962348#63#diseaseC0023492 | 10449776-5#9#13#gene9623 | 10449776-5#48#63#diseaseC0023492 | associated_with | TCL1,T cell leukemia |
| 9#13#gene962364#72#diseaseC0024299 | 10449776-5#9#13#gene9623 | 10449776-5#64#72#diseaseC0024299 | associated_with | TCL1,lymphoma |
| 9#13#gene811548#63#diseaseC0023492 | 10449776-5#9#13#gene8115 | 10449776-5#48#63#diseaseC0023492 | associated_with | TCL1,T cell leukemia |
| 9#13#gene811564#72#diseaseC0024299 | 10449776-5#9#13#gene8115 | 10449776-5#64#72#diseaseC0024299 | associated_with | TCL1,lymphoma |
| 9#13#gene962348#63#diseaseC0023492 | 10449776-5#9#13#gene9623 | 10449776-5#48#63#diseaseC0023492 | associated_with | TCL1,T cell leukemia |
| 9#13#gene962364#72#diseaseC0024299 | 10449776-5#9#13#gene9623 | 10449776-5#64#72#diseaseC0024299 | associated_with | TCL1,lymphoma |
| 55#59#gene81150#23#diseaseC0340782 | 10449776-9#55#59#gene8115 | 10449776-9#0#23#diseaseC0340782 | associated_with | TCL1,Hyperplastic lymph node |
| 55#59#gene96230#23#diseaseC0340782 | 10449776-9#55#59#gene9623 | 10449776-9#0#23#diseaseC0340782 | associated_with | TCL1,Hyperplastic lymph node |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C6 | 0-13 | NP | denotes | TCL1 oncogene |
| C22 | 28-33 | NP | denotes | AIDS- |
| C23 | 73-78 | NP | denotes | AIDS- |
| C1 | 73-119 | NP | denotes | AIDS-related non-Hodgkin's lymphoma (AIDS NHL) |
| C2 | 212-220 | NP | denotes | AIDS NHL |
| C4 | 379-446 | NP | denotes | AIDS NHL designated immunoblastic lymphoma plasmacytoid (AIDS IBLP) |
| C7 | 503-520 | NP | denotes | the TCL1 oncogene |
| C5 | 535-545 | NP | denotes | AIDS IBLP- |
| C20 | 630-654 | NP | denotes | Aberrant TCL1 expression |
| C21 | 720-723 | NP | denotes | its |
| C9 | 803-818 | NP | denotes | TCL1 expression |
| C10 | 844-852 | NP | denotes | AIDS NHL |
| C17 | 867-871 | NP | denotes | TCL1 |
| C19 | 1309-1313 | NP | denotes | TCL1 |
| C15 | 1385-1394 | NP | denotes | AIDS IBLP |
| C18 | 1662-1666 | NP | denotes | TCL1 |
| R1 | C23 | C22 | coref-ident | AIDS-,AIDS- |
| R2 | C2 | C1 | coref-ident | AIDS NHL,AIDS-related non-Hodgkin's lymphoma (AIDS NHL) |
| R3 | C7 | C6 | coref-ident | the TCL1 oncogene,TCL1 oncogene |
| R4 | C5 | C4 | coref-ident | AIDS IBLP-,AIDS NHL designated immunoblastic lymphoma plasmacytoid (AIDS IBLP) |
| R5 | C21 | C20 | coref-pron | its,Aberrant TCL1 expression |
| R6 | C9 | C20 | coref-other | TCL1 expression,Aberrant TCL1 expression |
| R7 | C10 | C2 | coref-ident | AIDS NHL,AIDS NHL |
| R8 | C19 | C17 | coref-ident | TCL1,TCL1 |
| R9 | C15 | C5 | coref-ident | AIDS IBLP,AIDS IBLP- |
| R10 | C18 | C19 | coref-ident | TCL1,TCL1 |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-72 | Sentence | denotes | TCL1 oncogene expression in AIDS-related lymphomas and lymphoid tissues. |
| S2 | 73-192 | Sentence | denotes | AIDS-related non-Hodgkin's lymphoma (AIDS NHL) comprises a diverse and heterogeneous group of high-grade B cell tumors. |
| S3 | 193-333 | Sentence | denotes | Certain classes of AIDS NHL are associated with alterations in oncogenes or tumor-suppressor genes or infections by oncogenic herpesviruses. |
| S4 | 334-488 | Sentence | denotes | However, the clinically significant class of AIDS NHL designated immunoblastic lymphoma plasmacytoid (AIDS IBLP) lacks any consistent genetic alterations. |
| S5 | 489-629 | Sentence | denotes | We identified the TCL1 oncogene from a set of AIDS IBLP-associated cDNA fragments generated by subtractive hybridization with non-AIDS IBLP. |
| S6 | 630-793 | Sentence | denotes | Aberrant TCL1 expression has been implicated in T cell leukemia/lymphoma development, and its expression also has been seen in many established B cell tumor lines. |
| S7 | 794-853 | Sentence | denotes | However, TCL1 expression has not been reported in AIDS NHL. |
| S8 | 854-930 | Sentence | denotes | We find that TCL1 is expressed in the majority of AIDS IBLP tumors examined. |
| S9 | 931-1055 | Sentence | denotes | TCL1 protein expression is restricted to tumor cells in AIDS IBLP tissue samples analyzed with immunohistochemical staining. |
| S10 | 1056-1284 | Sentence | denotes | Hyperplastic lymph node and tonsil also exhibit strong TCL1 protein expression in mantle zone B cells and in rare interfollicular zone cells, whereas follicle-center B cells (centroblasts and centrocytes) show weaker expression. |
| S11 | 1285-1395 | Sentence | denotes | These results establish TCL1 as the most prevalent of all of the surveyed oncogenes associated with AIDS IBLP. |
| S12 | 1396-1597 | Sentence | denotes | They also indicate that abundant TCL1 expression in quiescent mantle zone B cells is down-regulated in activated germinal center follicular B cells in parallel to the known expression pattern of BCL-2. |
| S13 | 1598-1736 | Sentence | denotes | High-level expression in nonproliferating B cells suggests that TCL1 may function in protecting naïve preactivated B cells from apoptosis. |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-13 | DNA_domain_or_region | denotes | TCL1 oncogene |
| T2 | 28-50 | tissue | denotes | AIDS-related lymphomas |
| T3 | 55-71 | tissue | denotes | lymphoid tissues |
| T4 | 73-108 | other_name | denotes | AIDS-related non-Hodgkin's lymphoma |
| T5 | 110-118 | other_name | denotes | AIDS NHL |
| T6 | 167-191 | tissue | denotes | high-grade B cell tumors |
| T7 | 212-220 | other_name | denotes | AIDS NHL |
| T8 | 256-265 | DNA_family_or_group | denotes | oncogenes |
| T9 | 269-291 | DNA_family_or_group | denotes | tumor-suppressor genes |
| T10 | 309-332 | virus | denotes | oncogenic herpesviruses |
| T11 | 379-387 | other_name | denotes | AIDS NHL |
| T12 | 399-434 | other_name | denotes | immunoblastic lymphoma plasmacytoid |
| T13 | 436-445 | other_name | denotes | AIDS IBLP |
| T14 | 507-520 | DNA_domain_or_region | denotes | TCL1 oncogene |
| T15 | 535-544 | other_name | denotes | AIDS IBLP |
| T16 | 584-609 | other_name | denotes | subtractive hybridization |
| T17 | 615-619 | other_name | denotes | non- |
| T18 | 619-628 | other_name | denotes | AIDS IBLP |
| T19 | 639-643 | protein_molecule | denotes | TCL1 |
| T20 | 678-714 | other_name | denotes | T cell leukemia/lymphoma development |
| T21 | 774-792 | cell_line | denotes | B cell tumor lines |
| T22 | 803-807 | protein_molecule | denotes | TCL1 |
| T23 | 844-852 | other_name | denotes | AIDS NHL |
| T24 | 867-871 | protein_molecule | denotes | TCL1 |
| T25 | 904-913 | other_name | denotes | AIDS IBLP |
| T26 | 931-935 | protein_molecule | denotes | TCL1 |
| T27 | 987-996 | other_name | denotes | AIDS IBLP |
| T28 | 1026-1054 | other_name | denotes | immunohistochemical staining |
| T29 | 1056-1079 | body_part | denotes | Hyperplastic lymph node |
| T30 | 1084-1090 | body_part | denotes | tonsil |
| T31 | 1111-1115 | protein_molecule | denotes | TCL1 |
| T32 | 1138-1157 | cell_type | denotes | mantle zone B cells |
| T33 | 1170-1196 | cell_type | denotes | interfollicular zone cells |
| T34 | 1206-1229 | cell_type | denotes | follicle-center B cells |
| T35 | 1231-1243 | cell_type | denotes | centroblasts |
| T36 | 1248-1259 | cell_type | denotes | centrocytes |
| T37 | 1309-1313 | protein_molecule | denotes | TCL1 |
| T38 | 1359-1368 | DNA_family_or_group | denotes | oncogenes |
| T39 | 1385-1394 | other_name | denotes | AIDS IBLP |
| T40 | 1429-1433 | protein_molecule | denotes | TCL1 |
| T41 | 1448-1457 | cell_type | denotes | quiescent |
| T42 | 1458-1477 | cell_type | denotes | mantle zone B cells |
| T43 | 1509-1543 | cell_type | denotes | germinal center follicular B cells |
| T44 | 1591-1596 | protein_molecule | denotes | BCL-2 |
| T45 | 1623-1647 | cell_type | denotes | nonproliferating B cells |
| T46 | 1662-1666 | protein_molecule | denotes | TCL1 |
| T47 | 1694-1720 | cell_type | denotes | naïve preactivated B cells |
| T48 | 1726-1735 | other_name | denotes | apoptosis |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 0-4 | gene:9623 | denotes | TCL1 |
| T1 | 28-50 | disease:C0085090 | denotes | AIDS-related lymphomas |
| T2 | 0-4 | gene:8115 | denotes | TCL1 |
| T3 | 28-50 | disease:C0085090 | denotes | AIDS-related lymphomas |
| R1 | T0 | T1 | associated_with | TCL1,AIDS-related lymphomas |
| R2 | T2 | T3 | associated_with | TCL1,AIDS-related lymphomas |