> top > docs > PubMed:10425206 > annotations

PubMed:10425206 JSONTXT

Annnotations TAB JSON ListView MergeView

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 735-745 HP_0003651 denotes foam cells

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-9 protein denotes PPARgamma
T2 51-92 DNA denotes adipocyte fatty acid binding protein gene
T3 96-111 cell_type denotes human monocytes
T4 117-165 protein denotes peroxisome-proliferator activated receptor gamma
T5 167-176 protein denotes PPARgamma
T6 195-223 protein denotes nuclear receptor superfamily
T7 227-265 protein denotes ligand activated transcription factors
T8 347-356 protein denotes PPARgamma
T9 388-393 DNA denotes genes
T10 437-473 protein denotes adipocyte fatty acid binding protein
T11 475-478 protein denotes aP2
T12 507-516 cell_type denotes adipocyte
T13 534-543 protein denotes PPARgamma
T14 565-584 cell_type denotes hematopoietic cells
T15 618-639 cell_type denotes monocytes/macrophages
T16 655-664 protein denotes PPARgamma
T17 720-731 cell_type denotes macrophages
T18 735-745 cell_type denotes foam cells
T19 902-910 RNA denotes aP2 mRNA
T20 919-942 cell_type denotes primary human monocytes
T21 951-970 cell_line denotes monocytic cell line
T22 972-977 cell_line denotes THP-1
T23 1003-1012 protein denotes PPARgamma
T24 1043-1051 cell_type denotes monocyte
T25 1125-1136 cell_type denotes adipocytes.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C8 0-20 NP denotes PPARgamma activation
C1 113-177 NP denotes The peroxisome-proliferator activated receptor gamma (PPARgamma)
C2 179-265 NP denotes a member of the nuclear receptor superfamily of ligand activated transcription factors
C3 347-356 NP denotes PPARgamma
C5 534-543 NP denotes PPARgamma
C6 655-664 NP denotes PPARgamma
C7 641-664 NP denotes Activation of PPARgamma
C9 740-745 NP denotes cells
C10 746-750 NP denotes that
C11 947-970 NP denotes the monocytic cell line
C12 972-977 NP denotes THP-1
C13 1003-1023 NP denotes PPARgamma activation
C14 1094-1097 NP denotes its
R1 C2 C1 coref-appos a member of the nuclear receptor superfamily of ligand activated transcription factors,The peroxisome-proliferator activated receptor gamma (PPARgamma)
R2 C3 C1 coref-ident PPARgamma,The peroxisome-proliferator activated receptor gamma (PPARgamma)
R3 C5 C3 coref-ident PPARgamma,PPARgamma
R4 C6 C5 coref-ident PPARgamma,PPARgamma
R5 C7 C8 coref-ident Activation of PPARgamma,PPARgamma activation
R6 C10 C9 coref-relat that,cells
R7 C12 C11 coref-appos THP-1,the monocytic cell line
R8 C13 C7 coref-ident PPARgamma activation,Activation of PPARgamma
R9 C14 C13 coref-pron its,PPARgamma activation

semrep-sample

Id Subject Object Predicate Lexical cue
E1-ti-1 0-20 cui:C1514758 denotes PPARgamma activation
E2-ti-1 33-43 cui:C0185117 denotes expression
E3-ti-1 51-60 cui:C0206131 denotes adipocyte
E4-ti-1 61-87 cui:C0060095 denotes fatty acid binding protein
E5-ti-1 88-92 cui:C0017337 denotes gene
E6-ti-1 96-101 cui:C0020114 denotes human
E7-ti-1 102-111 cui:C0026473 denotes monocytes
T1 33-43 PART_OF denotes expression
T2 51-87 PART_OF denotes adipocyte fatty acid binding protein
T3 96-111 PART_OF denotes human monocytes
E1-ab-1 117-165 cui:C0166417 denotes peroxisome-proliferator activated receptor gamma
E2-ab-1 181-187 cui:C0680022 denotes member
E3-ab-1 195-211 cui:C0206588 denotes nuclear receptor
E4-ab-1 227-233 cui:C1167622 denotes ligand
E5-ab-1 244-265 cui:C0040648 denotes transcription factors
E6-ab-1 275-278 cui:C1554080 denotes key
E7-ab-1 279-283 cui:C0035820 denotes role
E8-ab-1 296-304 cui:C0241863 denotes diabetic
E9-ab-1 320-338 cui:C1257987 denotes thiazolidinediones
T4 234-243 STIMULATES denotes activated
E1-ab-2 347-356 cui:C0597357 denotes PPARgamma
E2-ab-2 369-379 cui:C0185117 denotes expression
E3-ab-2 388-393 cui:C0017337 denotes genes
E4-ab-2 406-411 cui:C0023779 denotes lipid
E5-ab-2 412-421 cui:C0220781 denotes anabolism
E6-ab-2 437-446 cui:C0206131 denotes adipocyte
E7-ab-2 447-473 cui:C0060095 denotes fatty acid binding protein
E8-ab-2 475-478 cui:C0968902 denotes aP2
E9-ab-2 490-493 cui:C1554080 denotes key
E10-ab-2 507-532 cui:C1159884 denotes adipocyte differentiation
T5 394-402 AFFECTS denotes involved
T6 437-473 PART_OF denotes adipocyte fatty acid binding protein
T7 494-503 AFFECTS denotes regulator
E1-ab-3 534-543 cui:C0597357 denotes PPARgamma
E2-ab-3 565-578 cui:C0229601 denotes hematopoietic
E3-ab-3 579-584 cui:C0007634 denotes cells
E4-ab-3 608-617 cui:C1515877 denotes activated
E5-ab-3 618-639 cui:C1148382 denotes monocytes/macrophages
E1-ab-4 655-664 cui:C0597357 denotes PPARgamma
E2-ab-4 676-680 cui:C0035820 denotes role
E3-ab-4 688-697 cui:C0857127 denotes induction
E4-ab-4 720-731 cui:C0024432 denotes macrophages
E5-ab-4 735-745 cui:C0016390 denotes foam cells
E6-ab-4 771-786 cui:C0333482 denotes atherosclerotic
E7-ab-4 787-794 cui:C0221198 denotes lesions
E1-ab-5 816-823 cui:C0205296 denotes natural
E2-ab-5 838-847 cui:C0597357 denotes PPARgamma
E3-ab-5 848-856 cui:C0243192 denotes agonists
E4-ab-5 864-868 cui:C0040223 denotes time
E5-ab-5 874-888 cui:C1512045 denotes dose-dependent
E6-ab-5 889-898 cui:C0442805 denotes increases
E7-ab-5 902-905 cui:C0968902 denotes aP2
E8-ab-5 906-910 cui:C0035696 denotes mRNA
E9-ab-5 927-932 cui:C0020114 denotes human
E10-ab-5 933-942 cui:C0026473 denotes monocytes
E11-ab-5 951-960 cui:C0026473 denotes monocytic
E12-ab-5 961-970 cui:C0007600 denotes cell line
E13-ab-5 972-977 entrez:2736 denotes THP-1
T8 889-898 STIMULATES denotes increases
T9 927-942 PART_OF denotes human monocytes
T10 911-913 LOCATION_OF denotes in
T11 911-913 LOCATION_OF denotes in
E1-ab-6 985-989 cui:C1511726 denotes data
E2-ab-6 1003-1023 cui:C1514758 denotes PPARgamma activation
E3-ab-6 1035-1039 cui:C0035820 denotes role
E4-ab-6 1043-1067 cui:C1159954 denotes monocyte differentiation
E5-ab-6 1081-1090 cui:C0243071 denotes analogous
E6-ab-6 1098-1103 cui:C0205170 denotes well-
E7-ab-6 1117-1121 cui:C0035820 denotes role
E8-ab-6 1125-1135 cui:C0206131 denotes adipocytes
T12 1035-1039 AFFECTS denotes role
R1 E4-ti-1 T1 subjectOf fatty acid binding protein,expression
R2 E7-ti-1 T1 objectOf monocytes,expression
R3 E4-ti-1 T2 subjectOf fatty acid binding protein,adipocyte fatty acid binding protein
R4 E3-ti-1 T2 objectOf adipocyte,adipocyte fatty acid binding protein
R5 E7-ti-1 T3 subjectOf monocytes,human monocytes
R6 E6-ti-1 T3 objectOf human,human monocytes
R7 E1-ab-1 T4 subjectOf peroxisome-proliferator activated receptor gamma,activated
R8 E5-ab-1 T4 objectOf transcription factors,activated
R9 E3-ab-2 T5 subjectOf genes,involved
R10 E5-ab-2 T5 objectOf anabolism,involved
R11 E7-ab-2 T6 subjectOf fatty acid binding protein,adipocyte fatty acid binding protein
R12 E6-ab-2 T6 objectOf adipocyte,adipocyte fatty acid binding protein
R13 E8-ab-2 T7 subjectOf aP2,regulator
R14 E10-ab-2 T7 objectOf adipocyte differentiation,regulator
R15 E13-ab-5 T8 subjectOf THP-1,increases
R16 E7-ab-5 T8 objectOf aP2,increases
R17 E10-ab-5 T9 subjectOf monocytes,human monocytes
R18 E9-ab-5 T9 objectOf human,human monocytes
R19 E10-ab-5 T10 subjectOf monocytes,in
R20 E7-ab-5 T10 objectOf aP2,in
R21 E12-ab-5 T11 subjectOf cell line,in
R22 E7-ab-5 T11 objectOf aP2,in
R23 E2-ab-6 T12 subjectOf PPARgamma activation,role
R24 E4-ab-6 T12 objectOf monocyte differentiation,role

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-112 Sentence denotes PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes.
S2 113-346 Sentence denotes The peroxisome-proliferator activated receptor gamma (PPARgamma), a member of the nuclear receptor superfamily of ligand activated transcription factors, plays a key role in the anti-diabetic actions of the thiazolidinediones (TZDs).
S3 347-533 Sentence denotes PPARgamma induces the expression of many genes involved in lipid anabolism, including the adipocyte fatty acid binding protein (aP2), and is a key regulator of adipocyte differentiation.
S4 534-640 Sentence denotes PPARgamma is also expressed in hematopoietic cells and is up-regulated in activated monocytes/macrophages.
S5 641-795 Sentence denotes Activation of PPARgamma may play a role in the induction of differentiation of macrophages to foam cells that are associated with atherosclerotic lesions.
S6 796-978 Sentence denotes We report that both natural and synthetic PPARgamma agonists induce time- and dose-dependent increases in aP2 mRNA in both primary human monocytes and the monocytic cell line, THP-1.
S7 979-1136 Sentence denotes These data suggest that PPARgamma activation may play a role in monocyte differentiation and function analogous to its well-characterized role in adipocytes.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-9 protein_molecule denotes PPARgamma
T2 51-87 protein_molecule denotes adipocyte fatty acid binding protein
T3 96-111 cell_type denotes human monocytes
T4 117-165 protein_molecule denotes peroxisome-proliferator activated receptor gamma
T5 167-176 protein_molecule denotes PPARgamma
T6 195-223 protein_family_or_group denotes nuclear receptor superfamily
T7 227-265 protein_family_or_group denotes ligand activated transcription factors
T8 291-312 other_name denotes anti-diabetic actions
T9 320-338 other_organic_compound denotes thiazolidinediones
T10 340-344 other_organic_compound denotes TZDs
T11 347-356 protein_molecule denotes PPARgamma
T12 388-393 DNA_family_or_group denotes genes
T13 406-421 other_name denotes lipid anabolism
T14 437-473 protein_molecule denotes adipocyte fatty acid binding protein
T15 475-478 protein_molecule denotes aP2
T16 507-516 cell_type denotes adipocyte
T17 534-543 protein_molecule denotes PPARgamma
T18 565-584 cell_type denotes hematopoietic cells
T19 618-628 cell_type denotes monocytes/
T20 628-639 cell_type denotes macrophages
T21 655-664 protein_molecule denotes PPARgamma
T22 720-731 cell_type denotes macrophages
T23 735-745 cell_type denotes foam cells
T24 771-794 tissue denotes atherosclerotic lesions
T25 902-905 protein_molecule denotes aP2
T26 919-926 cell_type denotes primary
T27 927-942 cell_type denotes human monocytes
T28 951-970 cell_line denotes monocytic cell line
T29 972-977 cell_line denotes THP-1
T30 1003-1012 protein_molecule denotes PPARgamma
T31 1043-1051 cell_type denotes monocyte
T32 1125-1136 cell_type denotes adipocytes.

metamap-sample

Id Subject Object Predicate Lexical cue
T1 928-933 C0086418 denotes uman
T2 97-102 C0086418 denotes uman
T3 934-943 C0026473 denotes onocytes
T4 952-961 C0026473 denotes onocytic
T5 103-112 C0026473 denotes onocytes.
T6 858-864 C0205263 denotes nduce
T7 358-365 C0205263 denotes nduces
T8 22-29 C0205263 denotes nduces
T9 438-474 C1333527 denotes dipocyte fatty acid binding protein
T10 1004-1024 C1514758 denotes PARgamma activation
T11 1-21 C1514758 denotes PARgamma activation
T12 1004-1013 C1879547 denotes PARgamma
T13 839-848 C1879547 denotes PARgamma
T14 656-665 C1879547 denotes PARgamma
T15 535-544 C1879547 denotes PARgamma
T16 609-618 C1879547 denotes ctivated
T17 348-356 C1879547 denotes PARgamma
T18 235-244 C1879547 denotes ctivated
T19 1-10 C1879547 denotes PARgamma
T20 1004-1013 C1552644 denotes PARgamma
T21 839-848 C1552644 denotes PARgamma
T22 656-665 C1552644 denotes PARgamma
T23 535-544 C1552644 denotes PARgamma
T24 348-356 C1552644 denotes PARgamma
T25 1-10 C1552644 denotes PARgamma
T26 829-848 C3494280 denotes ynthetic PPARgamma
T27 321-339 C1257987 denotes hiazolidinediones
T28 1029-1033 C0600138 denotes lay
T29 670-673 C0600138 denotes lay
T30 268-273 C0600138 denotes lays
T31 1073-1081 C0031843 denotes unction
T32 677-681 C1705810 denotes ole
T33 280-284 C1705810 denotes ole
T34 407-422 C1563744 denotes ipid anabolism,
T35 196-212 C0206588 denotes uclear receptor
T36 907-911 C0035696 denotes RNA
T37 228-234 C0023688 denotes igand
T38 721-732 C0024432 denotes acrophages
T39 1126-1136 C0206131 denotes dipocytes.
T40 245-266 C0040648 denotes ranscription factors,
T41 962-971 C0007600 denotes ell line,
T42 849-857 C0243192 denotes gonists
T43 596-605 C0851285 denotes egulated
T44 865-869 C0040223 denotes ime-
T45 535-544 C0597357 denotes PARgamma
T46 348-356 C0597357 denotes PARgamma
T47 986-990 C1511726 denotes ata
T48 424-433 C0332257 denotes ncluding
T49 817-824 C0205296 denotes atural
T50 118-166 C1335238 denotes eroxisome-proliferator activated receptor gamma
T51 800-806 C0700287 denotes eport
T52 991-998 C1705535 denotes uggest
T53 973-976 C1705396 denotes HP-
T54 756-771 C0332281 denotes ssociated with
T55 566-585 C2323499 denotes ematopoietic cells
T56 619-640 C1148382 denotes onocytes/macrophages.
T57 772-787 C0333482 denotes therosclerotic
T58 395-403 C1314939 denotes nvolved
T59 788-795 C0221198 denotes esions.
T60 890-899 C0442805 denotes ncreases
T61 495-504 C1704735 denotes egulator
T62 593-595 C0547043 denotes p-
T63 182-188 C0680022 denotes ember
T64 920-927 C0205225 denotes rimary
T65 875-889 C1512045 denotes ose-dependent
T66 1104-1117 C1880022 denotes haracterized
T67 1099-1103 C0205170 denotes ell-
T68 196-203 C0521447 denotes uclear
T69 213-224 C1883220 denotes uperfamily
T70 306-313 C0441472 denotes ctions
T71 297-305 C0241863 denotes iabetic
T72 736-740 C0280592 denotes oam