PubMed:10381655 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T1	0-9	protein	denotes	NF-kappaB
T2	30-78	protein	denotes	proapoptotic and antiapoptotic regulatory factor
T3	115-124	protein	denotes	NF-kappaB
T4	198-215	cell_line	denotes	T cell hybridomas
T5	308-317	protein	denotes	NF-kappaB
T6	336-366	protein	denotes	dominant negative IkappaBalpha
T7	492-502	protein	denotes	Fas Ligand
T8	504-508	protein	denotes	FasL
T9	552-561	protein	denotes	NF-kappaB
T10	610-619	RNA	denotes	FasL mRNA
T11	694-703	protein	denotes	NF-kappaB
T12	709-728	protein	denotes	proapoptotic factor
T13	772-781	protein	denotes	NF-kappaB
T14	865-874	protein	denotes	NF-kappaB
T15	935-944	protein	denotes	NF-kappaB
T16	1012-1021	protein	denotes	NF-kappaB
T17	1065-1075	cell_type	denotes	thymocytes
T18	1122-1147	cell_type	denotes	mature peripheral T cells

Id	Subject	Object	Predicate	Lexical cue
C1	0-9	NP	denotes	NF-kappaB
C2	115-124	NP	denotes	NF-kappaB
C3	217-259	NP	denotes	both T cell activators and glucocorticoids
C4	267-276	NP	denotes	apoptosis
C5	308-326	NP	denotes	NF-kappaB activity
C6	392-419	NP	denotes	these two apoptotic signals
C7	527-536	NP	denotes	apoptosis
C8	552-570	NP	denotes	NF-kappaB activity
C9	647-656	NP	denotes	apoptosis
C10	694-703	NP	denotes	NF-kappaB
C11	707-728	NP	denotes	a proapoptotic factor
C12	772-781	NP	denotes	NF-kappaB
C13	865-874	NP	denotes	NF-kappaB
C14	893-916	NP	denotes	an antiapoptotic factor
C15	935-944	NP	denotes	NF-kappaB
C16	1012-1021	NP	denotes	NF-kappaB
C17	1038-1061	NP	denotes	an antiapoptotic factor
C18	1097-1118	NP	denotes	a proapoptotic factor
R1	C2	C1	coref-ident	NF-kappaB,NF-kappaB
R2	C6	C3	coref-ident	these two apoptotic signals,both T cell activators and glucocorticoids
R3	C7	C4	coref-ident	apoptosis,apoptosis
R4	C8	C5	coref-ident	NF-kappaB activity,NF-kappaB activity
R5	C9	C7	coref-ident	apoptosis,apoptosis
R6	C10	C2	coref-ident	NF-kappaB,NF-kappaB
R7	C12	C10	coref-ident	NF-kappaB,NF-kappaB
R8	C13	C12	coref-ident	NF-kappaB,NF-kappaB
R9	C15	C13	coref-ident	NF-kappaB,NF-kappaB
R10	C16	C15	coref-ident	NF-kappaB,NF-kappaB
R11	C17	C14	coref-ident	an antiapoptotic factor,an antiapoptotic factor
R12	C18	C11	coref-ident	a proapoptotic factor,a proapoptotic factor

Id	Subject	Object	Predicate	Lexical cue
S1	0-105	Sentence	denotes	NF-kappaB functions as both a proapoptotic and antiapoptotic regulatory factor within a single cell type.
S2	106-194	Sentence	denotes	Recently NF-kappaB has been shown to have both proapoptotic and antiapoptotic functions.
S3	195-277	Sentence	denotes	In T cell hybridomas, both T cell activators and glucocorticoids induce apoptosis.
S4	278-420	Sentence	denotes	Here we show that blockade of NF-kappaB activity, using a dominant negative IkappaBalpha, has opposite effects on these two apoptotic signals.
S5	421-537	Sentence	denotes	Treatment with PMA plus ionomycin (P/I) results in the upregulation of Fas Ligand (FasL) and induction of apoptosis.
S6	538-745	Sentence	denotes	Inhibition of NF-kappaB activity inhibits the P/I mediated induction of FasL mRNA and decreases the level of apoptosis in these cultures, thus establishing NF-kappaB as a proapoptotic factor in this context.
S7	746-917	Sentence	denotes	Conversely, inhibition of NF-kappaB confers a tenfold increase in glucocorticoid mediated apoptosis, establishing that NF-kappaB also functions as an antiapoptotic factor.
S8	918-988	Sentence	denotes	We conclude that NF-kappaB is a context-dependent apoptosis regulator.
S9	989-1148	Sentence	denotes	Our data suggests that NF-kappaB may function as an antiapoptotic factor in thymocytes while functioning as a proapoptotic factor in mature peripheral T cells.

Id	Subject	Object	Predicate	Lexical cue
T1	0-9	protein_complex	denotes	NF-kappaB
T2	115-124	protein_complex	denotes	NF-kappaB
T3	198-215	cell_line	denotes	T cell hybridomas
T4	222-239	other_name	denotes	T cell activators
T5	244-259	lipid	denotes	glucocorticoids
T6	267-276	other_name	denotes	apoptosis
T7	308-317	protein_molecule	denotes	NF-kappaB
T8	336-366	protein_molecule	denotes	dominant negative IkappaBalpha
T9	402-419	other_name	denotes	apoptotic signals
T10	436-439	other_organic_compound	denotes	PMA
T11	445-454	other_organic_compound	denotes	ionomycin
T12	456-459	other_organic_compound	denotes	P/I
T13	492-502	protein_molecule	denotes	Fas Ligand
T14	504-508	protein_molecule	denotes	FasL
T15	527-536	other_name	denotes	apoptosis
T16	552-561	protein_complex	denotes	NF-kappaB
T17	584-587	other_organic_compound	denotes	P/I
T18	610-614	protein_molecule	denotes	FasL
T19	647-656	other_name	denotes	apoptosis
T20	694-703	protein_complex	denotes	NF-kappaB
T21	709-728	protein_molecule	denotes	proapoptotic factor
T22	772-781	protein_molecule	denotes	NF-kappaB
T23	836-845	other_name	denotes	apoptosis
T24	865-874	protein_complex	denotes	NF-kappaB
T25	896-916	other_name	denotes	antiapoptotic factor
T26	935-944	protein_complex	denotes	NF-kappaB
T27	950-967	other_name	denotes	context-dependent
T28	968-977	other_name	denotes	apoptosis
T29	1012-1021	protein_complex	denotes	NF-kappaB
T30	1065-1075	cell_type	denotes	thymocytes
T31	1122-1147	cell_type	denotes	mature peripheral T cells