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PubMed:10229275 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 64-92 DNA denotes NF-kappaB-regulated promoter
T2 96-124 cell_type denotes monocyte-derived macrophages
T3 192-214 protein denotes common T-cell mitogens
T4 324-352 cell_type denotes monocyte-derived macrophages
T5 375-394 DNA denotes recombinant plasmid
T6 406-460 DNA denotes chloramphenicol acetyl transferase (CAT) reporter gene
T7 486-527 DNA denotes HIV-1 long terminal repeat (LTR) promoter
T8 551-571 protein denotes transcription factor
T9 572-581 protein denotes NF-kappaB
T10 681-698 DNA denotes CAT reporter gene
T11 732-741 protein denotes NF-kappaB
T12 761-770 protein denotes NF-kappaB
T13 815-829 protein denotes B7.1 molecules
T14 859-887 DNA denotes NF-kappaB-regulated promoter
T15 994-1022 cell_type denotes monocyte-derived macrophages

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-125 Sentence denotes High molecular weight dextran sulfate increases the activity of NF-kappaB-regulated promoter in monocyte-derived macrophages.
S2 126-215 Sentence denotes It is known that sulfated polysaccharides can mimic the action of common T-cell mitogens.
S3 216-582 Sentence denotes To investigate the molecular basis of the mitogenic effect of high molecular weight dextran sulfate (HMDS), monocyte-derived macrophages were transfected with recombinant plasmid containing chloramphenicol acetyl transferase (CAT) reporter gene under the control of the HIV-1 long terminal repeat (LTR) promoter, which is regulated by transcription factor NF-kappaB.
S4 583-742 Sentence denotes We observed that HMDS, similar to bacterial lipopolysaccharide (LPS), increases the expression of CAT reporter gene suggesting increased activity of NF-kappaB.
S5 743-830 Sentence denotes The activation of NF-kappaB correlated with the increased expression of B7.1 molecules.
S6 831-1023 Sentence denotes It was postulated that this NF-kappaB-regulated promoter might play a role in the activation of the accessory cells as well as the rate of replication of HIV-1 in monocyte-derived macrophages.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-37 NP denotes High molecular weight dextran sulfate
C2 64-92 NP denotes NF-kappaB-regulated promoter
C3 96-124 NP denotes monocyte-derived macrophages
C4 278-322 NP denotes high molecular weight dextran sulfate (HMDS)
C5 324-352 NP denotes monocyte-derived macrophages
C6 406-460 NP denotes chloramphenicol acetyl transferase (CAT) reporter gene
C7 482-527 NP denotes the HIV-1 long terminal repeat (LTR) promoter
C8 529-534 NP denotes which
C9 551-581 NP denotes transcription factor NF-kappaB
C10 600-604 NP denotes HMDS
C11 681-698 NP denotes CAT reporter gene
C12 732-741 NP denotes NF-kappaB
C13 761-770 NP denotes NF-kappaB
C14 854-887 NP denotes this NF-kappaB-regulated promoter
C15 994-1022 NP denotes monocyte-derived macrophages
R1 C4 C1 coref-ident high molecular weight dextran sulfate (HMDS),High molecular weight dextran sulfate
R2 C5 C3 coref-ident monocyte-derived macrophages,monocyte-derived macrophages
R3 C8 C7 coref-relat which,the HIV-1 long terminal repeat (LTR) promoter
R4 C10 C4 coref-ident HMDS,high molecular weight dextran sulfate (HMDS)
R5 C11 C6 coref-ident CAT reporter gene,chloramphenicol acetyl transferase (CAT) reporter gene
R6 C12 C9 coref-ident NF-kappaB,transcription factor NF-kappaB
R7 C13 C12 coref-ident NF-kappaB,NF-kappaB
R8 C14 C2 coref-ident this NF-kappaB-regulated promoter,NF-kappaB-regulated promoter
R9 C15 C5 coref-ident monocyte-derived macrophages,monocyte-derived macrophages

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-21 carbohydrate denotes High molecular weight
T2 22-37 carbohydrate denotes dextran sulfate
T3 64-73 protein_complex denotes NF-kappaB
T4 96-124 cell_type denotes monocyte-derived macrophages
T5 143-167 carbohydrate denotes sulfated polysaccharides
T6 192-214 protein_family_or_group denotes common T-cell mitogens
T7 258-274 other_name denotes mitogenic effect
T8 278-315 carbohydrate denotes high molecular weight dextran sulfate
T9 317-321 carbohydrate denotes HMDS
T10 324-352 cell_type denotes monocyte-derived macrophages
T11 375-394 DNA_molecule denotes recombinant plasmid
T12 406-440 protein_molecule denotes chloramphenicol acetyl transferase
T13 486-491 virus denotes HIV-1
T14 551-571 protein_family_or_group denotes transcription factor
T15 572-581 protein_complex denotes NF-kappaB
T16 600-604 carbohydrate denotes HMDS
T17 627-645 lipid denotes lipopolysaccharide
T18 647-650 lipid denotes LPS
T19 681-698 DNA_domain_or_region denotes CAT reporter gene
T20 732-741 protein_complex denotes NF-kappaB
T21 761-770 protein_complex denotes NF-kappaB
T22 815-829 protein_molecule denotes B7.1 molecules
T23 859-868 protein_complex denotes NF-kappaB
T24 985-990 virus denotes HIV-1
T25 994-1022 cell_type denotes monocyte-derived macrophages