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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 964-973 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T2 964-973 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 964-973 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-114 Sentence denotes Galectin-3 and polarized growth within collagen gels of wild-type and ricin-resistant MDCK renal epithelial cells.
TextSentencer_T2 115-135 Sentence denotes Previous studies (Q.
TextSentencer_T3 136-146 Sentence denotes Bao and R.
TextSentencer_T4 147-149 Sentence denotes C.
TextSentencer_T5 150-166 Sentence denotes Hughes (1995) J.
TextSentencer_T6 167-394 Sentence denotes Cell Sci., 108, 2791-2800) showed that the beta-galactoside-binding protein, galectin-3, is secreted onto the basolateral surface domains of Madin-Darby canine kidney MDCK cells growing as polarized cysts within a collagen gel.
TextSentencer_T7 395-606 Sentence denotes The growth and enlargement of such cysts were shown to be increased significantly when cultured in the presence of antibodies directed against the lectin and were slowed down by addition of exogenous galectin-3.
TextSentencer_T8 607-836 Sentence denotes These results suggested a role for galectin-3, interacting with appropriately glycosylated surface receptors, as a negative growth regulator in the development of MDCK cysts, a well-known model for renal epithelial morphogenesis.
TextSentencer_T9 837-1086 Sentence denotes In the present report we have tested this proposal by use of a ricin-resistant mutant of MDCK cells that is unable to transfer galactose residues during biosynthesis of cellular glycoconjugates and hence lacks extracellular receptors for galectin-3.
TextSentencer_T10 1087-1207 Sentence denotes We find that when grown within collagen gels, the mutant cell cysts grow significantly faster than wild-type cell cysts.
TextSentencer_T11 1208-1377 Sentence denotes Furthermore, they form nonspherical and tubular cysts that are induced in wild-type cell cysts only under the influence of the morphogen, hepatocyte growth factor (HGF).
T1 0-114 Sentence denotes Galectin-3 and polarized growth within collagen gels of wild-type and ricin-resistant MDCK renal epithelial cells.
T2 115-394 Sentence denotes Previous studies (Q. Bao and R. C. Hughes (1995) J. Cell Sci., 108, 2791-2800) showed that the beta-galactoside-binding protein, galectin-3, is secreted onto the basolateral surface domains of Madin-Darby canine kidney MDCK cells growing as polarized cysts within a collagen gel.
T3 395-606 Sentence denotes The growth and enlargement of such cysts were shown to be increased significantly when cultured in the presence of antibodies directed against the lectin and were slowed down by addition of exogenous galectin-3.
T4 607-836 Sentence denotes These results suggested a role for galectin-3, interacting with appropriately glycosylated surface receptors, as a negative growth regulator in the development of MDCK cysts, a well-known model for renal epithelial morphogenesis.
T5 837-1086 Sentence denotes In the present report we have tested this proposal by use of a ricin-resistant mutant of MDCK cells that is unable to transfer galactose residues during biosynthesis of cellular glycoconjugates and hence lacks extracellular receptors for galectin-3.
T6 1087-1207 Sentence denotes We find that when grown within collagen gels, the mutant cell cysts grow significantly faster than wild-type cell cysts.
T7 1208-1377 Sentence denotes Furthermore, they form nonspherical and tubular cysts that are induced in wild-type cell cysts only under the influence of the morphogen, hepatocyte growth factor (HGF).
T1 0-114 Sentence denotes Galectin-3 and polarized growth within collagen gels of wild-type and ricin-resistant MDCK renal epithelial cells.
T2 115-135 Sentence denotes Previous studies (Q.
T3 136-146 Sentence denotes Bao and R.
T4 147-149 Sentence denotes C.
T5 150-166 Sentence denotes Hughes (1995) J.
T6 167-394 Sentence denotes Cell Sci., 108, 2791-2800) showed that the beta-galactoside-binding protein, galectin-3, is secreted onto the basolateral surface domains of Madin-Darby canine kidney MDCK cells growing as polarized cysts within a collagen gel.
T7 395-606 Sentence denotes The growth and enlargement of such cysts were shown to be increased significantly when cultured in the presence of antibodies directed against the lectin and were slowed down by addition of exogenous galectin-3.
T8 607-836 Sentence denotes These results suggested a role for galectin-3, interacting with appropriately glycosylated surface receptors, as a negative growth regulator in the development of MDCK cysts, a well-known model for renal epithelial morphogenesis.
T9 837-1086 Sentence denotes In the present report we have tested this proposal by use of a ricin-resistant mutant of MDCK cells that is unable to transfer galactose residues during biosynthesis of cellular glycoconjugates and hence lacks extracellular receptors for galectin-3.
T10 1087-1207 Sentence denotes We find that when grown within collagen gels, the mutant cell cysts grow significantly faster than wild-type cell cysts.
T11 1208-1377 Sentence denotes Furthermore, they form nonspherical and tubular cysts that are induced in wild-type cell cysts only under the influence of the morphogen, hepatocyte growth factor (HGF).

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 964-973 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T2 964-973 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 327-333 http://purl.obolibrary.org/obo/MAT_0000119 denotes kidney

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 39-47 FMAID:63891 denotes collagen
_T2 39-47 FMAID:162361 denotes collagen
_T3 97-113 FMAID:164922 denotes epithelial cells
_T4 97-113 FMAID:165731 denotes epithelial cells
_T5 97-113 FMAID:67799 denotes epithelial cells
_T6 97-113 FMAID:83514 denotes epithelial cells
_T7 97-113 FMAID:165528 denotes epithelial cells
_T8 97-113 FMAID:197786 denotes epithelial cells
_T9 97-113 FMAID:67559 denotes epithelial cells
_T10 97-113 FMAID:66768 denotes epithelial cells
_T11 97-113 FMAID:169653 denotes epithelial cells
_T12 97-113 FMAID:69075 denotes epithelial cells
_T13 97-113 FMAID:69074 denotes epithelial cells
_T14 97-113 FMAID:169652 denotes epithelial cells
_T15 108-113 FMAID:68646 denotes cells
_T16 108-113 FMAID:169002 denotes cells
_T17 235-242 FMAID:165447 denotes protein
_T18 235-242 FMAID:67257 denotes protein
_T19 289-296 FMAID:146300 denotes surface
_T20 289-296 FMAID:50594 denotes surface
_T21 327-333 FMAID:7203 denotes kidney
_T22 327-333 FMAID:93681 denotes kidney
_T23 339-344 FMAID:68646 denotes cells
_T24 339-344 FMAID:169002 denotes cells
_T25 381-389 FMAID:63891 denotes collagen
_T26 381-389 FMAID:162361 denotes collagen
_T27 510-520 FMAID:167180 denotes antibodies
_T28 698-705 FMAID:146300 denotes surface
_T29 698-705 FMAID:50594 denotes surface
_T30 867-873 FMAID:178661 denotes tested
_T31 931-936 FMAID:68646 denotes cells
_T32 931-936 FMAID:169002 denotes cells
_T33 964-973 FMAID:82794 denotes galactose
_T34 964-973 FMAID:196789 denotes galactose
_T35 1015-1030 FMAID:196776 denotes glycoconjugates
_T36 1015-1030 FMAID:82782 denotes glycoconjugates
_T37 1118-1126 FMAID:63891 denotes collagen
_T38 1118-1126 FMAID:162361 denotes collagen
_T39 1346-1356 FMAID:104185 denotes hepatocyte
_T40 1346-1356 FMAID:14515 denotes hepatocyte
_T41 1346-1356 FMAID:242393 denotes hepatocyte

uniprot-human

Id Subject Object Predicate Lexical cue
T1 0-10 http://www.uniprot.org/uniprot/P17931 denotes Galectin-3
T2 244-254 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T3 595-605 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T4 642-652 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T5 215-242 http://www.uniprot.org/uniprot/P17931 denotes galactoside-binding protein
T6 227-254 http://www.uniprot.org/uniprot/Q08380 denotes binding protein, galectin-3
T7 227-254 http://www.uniprot.org/uniprot/A6NE02 denotes binding protein, galectin-3
T8 1346-1370 http://www.uniprot.org/uniprot/Q9BYM0 denotes hepatocyte growth factor
T9 1372-1375 http://www.uniprot.org/uniprot/Q9BYM0 denotes HGF
T10 1346-1370 http://www.uniprot.org/uniprot/P08581 denotes hepatocyte growth factor
T11 1346-1370 http://www.uniprot.org/uniprot/Q04756 denotes hepatocyte growth factor

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 0-10 http://www.uniprot.org/uniprot/P16110 denotes Galectin-3
T2 244-254 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T3 595-605 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T4 642-652 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T5 1075-1085 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T6 227-254 http://www.uniprot.org/uniprot/Q07797 denotes binding protein, galectin-3

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 108-113 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T2 210-214 http://purl.bioontology.org/ontology/NCBITAXON/3554 denotes beta
T3 210-214 http://purl.bioontology.org/ontology/NCBITAXON/158455 denotes beta
T4 339-344 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T5 706-715 http://purl.bioontology.org/ontology/STY/T192 denotes receptors
T6 931-936 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T7 1061-1070 http://purl.bioontology.org/ontology/STY/T192 denotes receptors
T8 1090-1094 http://purl.bioontology.org/ontology/STY/T033 denotes find

GO-BP

Id Subject Object Predicate Lexical cue
T1 25-31 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T2 399-405 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T3 731-737 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T4 1357-1363 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T5 70-75 http://purl.obolibrary.org/obo/GO_0030598 denotes ricin
T6 900-905 http://purl.obolibrary.org/obo/GO_0030598 denotes ricin
T7 259-267 http://purl.obolibrary.org/obo/GO_0046903 denotes secreted
T8 585-594 http://purl.obolibrary.org/obo/GO_0042638 denotes exogenous
T9 685-697 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylated
T10 722-747 http://purl.obolibrary.org/obo/GO_0045926 denotes negative growth regulator
T11 722-747 http://purl.obolibrary.org/obo/GO_2000221 denotes negative growth regulator
T12 722-747 http://purl.obolibrary.org/obo/GO_0010977 denotes negative growth regulator
T13 722-747 http://purl.obolibrary.org/obo/GO_0040015 denotes negative growth regulator
T14 722-747 http://purl.obolibrary.org/obo/GO_2000604 denotes negative growth regulator
T15 722-747 http://purl.obolibrary.org/obo/GO_0046621 denotes negative growth regulator
T16 722-747 http://purl.obolibrary.org/obo/GO_0061117 denotes negative growth regulator
T17 722-747 http://purl.obolibrary.org/obo/GO_0030308 denotes negative growth regulator
T18 722-747 http://purl.obolibrary.org/obo/GO_0045967 denotes negative growth regulator
T19 722-747 http://purl.obolibrary.org/obo/GO_0048640 denotes negative growth regulator
T20 731-747 http://purl.obolibrary.org/obo/GO_0009725 denotes growth regulator
T21 738-747 http://purl.obolibrary.org/obo/GO_0065007 denotes regulator
T22 755-766 http://purl.obolibrary.org/obo/GO_0032502 denotes development
T23 822-835 http://purl.obolibrary.org/obo/GO_0009653 denotes morphogenesis
T24 990-1002 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T25 990-1014 http://purl.obolibrary.org/obo/GO_0044249 denotes biosynthesis of cellular
T26 1006-1014 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular

GO-MF

Id Subject Object Predicate Lexical cue
T1 215-234 http://purl.obolibrary.org/obo/GO_0016936 denotes galactoside-binding
T2 227-234 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T3 227-234 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T4 227-234 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T5 227-234 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T6 227-242 http://purl.obolibrary.org/obo/GO_0005515 denotes binding protein
T7 510-520 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies

GO-CC

Id Subject Object Predicate Lexical cue
T1 108-113 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T2 339-344 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T3 167-171 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T4 1144-1148 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T5 1196-1200 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T6 1292-1296 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T7 1047-1060 http://purl.obolibrary.org/obo/GO_0005576 denotes extracellular

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 327-333 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 124-131 http://edamontology.org/topic_3678 denotes studies
T2 235-242 http://edamontology.org/topic_0078 denotes protein
T3 654-665 http://edamontology.org/topic_0602 denotes interacting

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 235-242 http://edamontology.org/format_1208 denotes protein
T2 235-242 http://edamontology.org/data_1467 denotes protein
T3 852-858 http://edamontology.org/data_2048 denotes report
T4 974-982 http://edamontology.org/data_1756 denotes residues

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 327-333 http://purl.obolibrary.org/obo/MAT_0000119 denotes kidney

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 0-8 https://acgg.asia/db/lfdb/LfDB0270 denotes Galectin
Lectin_T2 0-8 https://acgg.asia/db/lfdb/LfDB0272 denotes Galectin
Lectin_T3 0-8 https://acgg.asia/db/lfdb/LfDB0274 denotes Galectin

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 327-333 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 327-333 Body_part denotes kidney http://purl.obolibrary.org/obo/MAT_0000119

Lectin-Jamboree

Id Subject Object Predicate Lexical cue
T1 542-548 lectin denotes lectin

Lectin-Jamboree-Sentence

Id Subject Object Predicate Lexical cue
T1 0-114 Sentence denotes Galectin-3 and polarized growth within collagen gels of wild-type and ricin-resistant MDCK renal epithelial cells.
T2 115-394 Sentence denotes Previous studies (Q. Bao and R. C. Hughes (1995) J. Cell Sci., 108, 2791-2800) showed that the beta-galactoside-binding protein, galectin-3, is secreted onto the basolateral surface domains of Madin-Darby canine kidney MDCK cells growing as polarized cysts within a collagen gel.
T3 395-606 Sentence denotes The growth and enlargement of such cysts were shown to be increased significantly when cultured in the presence of antibodies directed against the lectin and were slowed down by addition of exogenous galectin-3.
T4 607-836 Sentence denotes These results suggested a role for galectin-3, interacting with appropriately glycosylated surface receptors, as a negative growth regulator in the development of MDCK cysts, a well-known model for renal epithelial morphogenesis.
T5 837-1086 Sentence denotes In the present report we have tested this proposal by use of a ricin-resistant mutant of MDCK cells that is unable to transfer galactose residues during biosynthesis of cellular glycoconjugates and hence lacks extracellular receptors for galectin-3.
T6 1087-1207 Sentence denotes We find that when grown within collagen gels, the mutant cell cysts grow significantly faster than wild-type cell cysts.
T7 1208-1377 Sentence denotes Furthermore, they form nonspherical and tubular cysts that are induced in wild-type cell cysts only under the influence of the morphogen, hepatocyte growth factor (HGF).

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 97-113 Body_part denotes epithelial cells http://purl.obolibrary.org/obo/CL_0000066
T2 320-326 Body_part denotes canine http://purl.obolibrary.org/obo/UBERON_0003674
T3 327-333 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T4 1047-1060 Body_part denotes extracellular http://purl.obolibrary.org/obo/GO_0005576
T5 1346-1356 Body_part denotes hepatocyte http://purl.obolibrary.org/obo/CL_0000182

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 97-113 Cell denotes epithelial cells http://purl.obolibrary.org/obo/CL:0000066
T2 1346-1356 Cell denotes hepatocyte http://purl.obolibrary.org/obo/CL:0000182