PubMed:10207023 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/10207023","sourcedb":"PubMed","sourceid":"10207023","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/10207023","text":"Modulation of E2F complexes during G0 to S phase transition in human primary B-lymphocytes.\nThe pocket protein-E2F complexes are convergence points for cell cycle signaling. In the present report, we identified and monitored the pocket protein-E2F complexes in human primary B-lymphocytes after activation by phorbol 12-myristate 13-acetate. Consistent with previous data from human and mouse fibroblasts and T-lymphocytes, E2F4 and DP1 form the predominant E2F heterodimers both in G0 and G1 phases of the human B-lymphocyte cell cycle, whereas E2F1 and -3 are first detected in late G1, and their expression levels increase towards S phase. Intriguingly, the major E2F complex that we detected in quiescent human B-lymphocytes is consisted of pRB, E2F4, and DP1. Though the levels of DP1 and -2 increase when cells progress from G0 to S, the proportion of DP1 to DP2 remains relatively constant during the cell cycle. We also observed an increase in electrophoretic mobility of the predominant E2F components, DP1 and E2F4, as B-lymphocytes progressed from G0 into early G1. This increase in mobility was attributable to dephosphorylation, as lambda phosphatase treatment could convert the slower migrating forms into the corresponding faster mobility forms. We further demonstrated that this change in phosphorylation status correlates with a decrease in DNA binding activity. This modulation of DNA binding activity mediated through the dephosphorylation of DP1 and E2F4 could help to explain the lack of in vivo DNA footprinting in late G1 and S phases of gene promoters negatively regulated through E2F sites and suggests a novel mechanism for controlling E2F transcriptional activity during the transition from quiescence to proliferation.","tracks":[{"project":"genia-medco-coref","denotations":[{"id":"C1","span":{"begin":14,"end":27},"obj":"NP"},{"id":"C2","span":{"begin":63,"end":90},"obj":"NP"},{"id":"C3","span":{"begin":92,"end":124},"obj":"NP"},{"id":"C4","span":{"begin":261,"end":288},"obj":"NP"},{"id":"C5","span":{"begin":424,"end":428},"obj":"NP"},{"id":"C6","span":{"begin":433,"end":436},"obj":"NP"},{"id":"C7","span":{"begin":546,"end":557},"obj":"NP"},{"id":"C8","span":{"begin":593,"end":598},"obj":"NP"},{"id":"C9","span":{"begin":657,"end":678},"obj":"NP"},{"id":"C10","span":{"begin":679,"end":683},"obj":"NP"},{"id":"C11","span":{"begin":750,"end":754},"obj":"NP"},{"id":"C12","span":{"begin":760,"end":763},"obj":"NP"},{"id":"C13","span":{"begin":858,"end":861},"obj":"NP"},{"id":"C14","span":{"begin":980,"end":1010},"obj":"NP"},{"id":"C16","span":{"begin":1012,"end":1015},"obj":"NP"},{"id":"C17","span":{"begin":1020,"end":1024},"obj":"NP"},{"id":"C15","span":{"begin":1012,"end":1024},"obj":"NP"},{"id":"C18","span":{"begin":1358,"end":1378},"obj":"NP"},{"id":"C19","span":{"begin":1399,"end":1419},"obj":"NP"},{"id":"C21","span":{"begin":1462,"end":1465},"obj":"NP"},{"id":"C22","span":{"begin":1470,"end":1474},"obj":"NP"},{"id":"C20","span":{"begin":1462,"end":1474},"obj":"NP"}],"relations":[{"id":"R1","pred":"coref-ident","subj":"C3","obj":"C1"},{"id":"R2","pred":"coref-ident","subj":"C4","obj":"C2"},{"id":"R3","pred":"coref-pron","subj":"C8","obj":"C7"},{"id":"R4","pred":"coref-relat","subj":"C10","obj":"C9"},{"id":"R5","pred":"coref-ident","subj":"C11","obj":"C5"},{"id":"R6","pred":"coref-ident","subj":"C12","obj":"C6"},{"id":"R7","pred":"coref-ident","subj":"C13","obj":"C12"},{"id":"R8","pred":"coref-ident","subj":"C16","obj":"C13"},{"id":"R9","pred":"coref-ident","subj":"C17","obj":"C11"},{"id":"R10","pred":"coref-appos","subj":"C15","obj":"C14"},{"id":"R11","pred":"coref-ident","subj":"C19","obj":"C18"},{"id":"R12","pred":"coref-ident","subj":"C21","obj":"C16"},{"id":"R13","pred":"coref-ident","subj":"C22","obj":"C17"},{"id":"R14","pred":"coref-ident","subj":"C20","obj":"C14"}],"attributes":[{"subj":"C1","pred":"source","obj":"genia-medco-coref"},{"subj":"C2","pred":"source","obj":"genia-medco-coref"},{"subj":"C3","pred":"source","obj":"genia-medco-coref"},{"subj":"C4","pred":"source","obj":"genia-medco-coref"},{"subj":"C5","pred":"source","obj":"genia-medco-coref"},{"subj":"C6","pred":"source","obj":"genia-medco-coref"},{"subj":"C7","pred":"source","obj":"genia-medco-coref"},{"subj":"C8","pred":"source","obj":"genia-medco-coref"},{"subj":"C9","pred":"source","obj":"genia-medco-coref"},{"subj":"C10","pred":"source","obj":"genia-medco-coref"},{"subj":"C11","pred":"source","obj":"genia-medco-coref"},{"subj":"C12","pred":"source","obj":"genia-medco-coref"},{"subj":"C13","pred":"source","obj":"genia-medco-coref"},{"subj":"C14","pred":"source","obj":"genia-medco-coref"},{"subj":"C16","pred":"source","obj":"genia-medco-coref"},{"subj":"C17","pred":"source","obj":"genia-medco-coref"},{"subj":"C15","pred":"source","obj":"genia-medco-coref"},{"subj":"C18","pred":"source","obj":"genia-medco-coref"},{"subj":"C19","pred":"source","obj":"genia-medco-coref"},{"subj":"C21","pred":"source","obj":"genia-medco-coref"},{"subj":"C22","pred":"source","obj":"genia-medco-coref"},{"subj":"C20","pred":"source","obj":"genia-medco-coref"}]},{"project":"jnlpba-st-training","denotations":[{"id":"T1","span":{"begin":14,"end":27},"obj":"protein"},{"id":"T2","span":{"begin":63,"end":90},"obj":"cell_type"},{"id":"T3","span":{"begin":96,"end":124},"obj":"protein"},{"id":"T4","span":{"begin":229,"end":257},"obj":"protein"},{"id":"T5","span":{"begin":261,"end":288},"obj":"cell_type"},{"id":"T6","span":{"begin":377,"end":404},"obj":"cell_type"},{"id":"T7","span":{"begin":409,"end":422},"obj":"cell_type"},{"id":"T8","span":{"begin":424,"end":428},"obj":"protein"},{"id":"T9","span":{"begin":433,"end":436},"obj":"protein"},{"id":"T10","span":{"begin":458,"end":474},"obj":"protein"},{"id":"T11","span":{"begin":546,"end":557},"obj":"protein"},{"id":"T12","span":{"begin":661,"end":678},"obj":"protein"},{"id":"T13","span":{"begin":699,"end":728},"obj":"cell_type"},{"id":"T14","span":{"begin":745,"end":748},"obj":"protein"},{"id":"T15","span":{"begin":750,"end":754},"obj":"protein"},{"id":"T16","span":{"begin":760,"end":763},"obj":"protein"},{"id":"T17","span":{"begin":786,"end":796},"obj":"protein"},{"id":"T18","span":{"begin":858,"end":861},"obj":"protein"},{"id":"T19","span":{"begin":865,"end":868},"obj":"protein"},{"id":"T20","span":{"begin":996,"end":1010},"obj":"protein"},{"id":"T21","span":{"begin":1012,"end":1015},"obj":"protein"},{"id":"T22","span":{"begin":1020,"end":1024},"obj":"protein"},{"id":"T23","span":{"begin":1029,"end":1042},"obj":"cell_type"},{"id":"T24","span":{"begin":1192,"end":1214},"obj":"protein"},{"id":"T25","span":{"begin":1224,"end":1259},"obj":"protein"},{"id":"T26","span":{"begin":1462,"end":1465},"obj":"protein"},{"id":"T27","span":{"begin":1470,"end":1474},"obj":"protein"},{"id":"T28","span":{"begin":1561,"end":1575},"obj":"DNA"},{"id":"T29","span":{"begin":1605,"end":1614},"obj":"DNA"},{"id":"T30","span":{"begin":1662,"end":1665},"obj":"protein"}],"attributes":[{"subj":"T1","pred":"source","obj":"jnlpba-st-training"},{"subj":"T2","pred":"source","obj":"jnlpba-st-training"},{"subj":"T3","pred":"source","obj":"jnlpba-st-training"},{"subj":"T4","pred":"source","obj":"jnlpba-st-training"},{"subj":"T5","pred":"source","obj":"jnlpba-st-training"},{"subj":"T6","pred":"source","obj":"jnlpba-st-training"},{"subj":"T7","pred":"source","obj":"jnlpba-st-training"},{"subj":"T8","pred":"source","obj":"jnlpba-st-training"},{"subj":"T9","pred":"source","obj":"jnlpba-st-training"},{"subj":"T10","pred":"source","obj":"jnlpba-st-training"},{"subj":"T11","pred":"source","obj":"jnlpba-st-training"},{"subj":"T12","pred":"source","obj":"jnlpba-st-training"},{"subj":"T13","pred":"source","obj":"jnlpba-st-training"},{"subj":"T14","pred":"source","obj":"jnlpba-st-training"},{"subj":"T15","pred":"source","obj":"jnlpba-st-training"},{"subj":"T16","pred":"source","obj":"jnlpba-st-training"},{"subj":"T17","pred":"source","obj":"jnlpba-st-training"},{"subj":"T18","pred":"source","obj":"jnlpba-st-training"},{"subj":"T19","pred":"source","obj":"jnlpba-st-training"},{"subj":"T20","pred":"source","obj":"jnlpba-st-training"},{"subj":"T21","pred":"source","obj":"jnlpba-st-training"},{"subj":"T22","pred":"source","obj":"jnlpba-st-training"},{"subj":"T23","pred":"source","obj":"jnlpba-st-training"},{"subj":"T24","pred":"source","obj":"jnlpba-st-training"},{"subj":"T25","pred":"source","obj":"jnlpba-st-training"},{"subj":"T26","pred":"source","obj":"jnlpba-st-training"},{"subj":"T27","pred":"source","obj":"jnlpba-st-training"},{"subj":"T28","pred":"source","obj":"jnlpba-st-training"},{"subj":"T29","pred":"source","obj":"jnlpba-st-training"},{"subj":"T30","pred":"source","obj":"jnlpba-st-training"}]},{"project":"sentences","denotations":[{"id":"T1","span":{"begin":0,"end":91},"obj":"Sentence"},{"id":"T2","span":{"begin":92,"end":173},"obj":"Sentence"},{"id":"T3","span":{"begin":174,"end":341},"obj":"Sentence"},{"id":"T4","span":{"begin":342,"end":642},"obj":"Sentence"},{"id":"T5","span":{"begin":643,"end":764},"obj":"Sentence"},{"id":"T6","span":{"begin":765,"end":919},"obj":"Sentence"},{"id":"T7","span":{"begin":920,"end":1076},"obj":"Sentence"},{"id":"T8","span":{"begin":1077,"end":1260},"obj":"Sentence"},{"id":"T9","span":{"begin":1261,"end":1379},"obj":"Sentence"},{"id":"T10","span":{"begin":1380,"end":1746},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T1","pred":"source","obj":"sentences"},{"subj":"T2","pred":"source","obj":"sentences"},{"subj":"T3","pred":"source","obj":"sentences"},{"subj":"T4","pred":"source","obj":"sentences"},{"subj":"T5","pred":"source","obj":"sentences"},{"subj":"T6","pred":"source","obj":"sentences"},{"subj":"T7","pred":"source","obj":"sentences"},{"subj":"T8","pred":"source","obj":"sentences"},{"subj":"T9","pred":"source","obj":"sentences"},{"subj":"T10","pred":"source","obj":"sentences"}]},{"project":"NCBITAXON","denotations":[{"id":"T2","span":{"begin":261,"end":266},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":377,"end":382},"obj":"OrganismTaxon"},{"id":"T4","span":{"begin":387,"end":392},"obj":"OrganismTaxon"},{"id":"T6","span":{"begin":507,"end":512},"obj":"OrganismTaxon"},{"id":"T7","span":{"begin":709,"end":714},"obj":"OrganismTaxon"},{"id":"T1","span":{"begin":63,"end":68},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"9606"},{"id":"A2","pred":"db_id","subj":"T2","obj":"9606"},{"id":"A3","pred":"db_id","subj":"T3","obj":"9606"},{"id":"A4","pred":"db_id","subj":"T4","obj":"10088"},{"id":"A5","pred":"db_id","subj":"T4","obj":"10090"},{"id":"A6","pred":"db_id","subj":"T6","obj":"9606"},{"id":"A7","pred":"db_id","subj":"T7","obj":"9606"},{"subj":"T2","pred":"source","obj":"NCBITAXON"},{"subj":"T3","pred":"source","obj":"NCBITAXON"},{"subj":"T4","pred":"source","obj":"NCBITAXON"},{"subj":"T6","pred":"source","obj":"NCBITAXON"},{"subj":"T7","pred":"source","obj":"NCBITAXON"},{"subj":"T1","pred":"source","obj":"NCBITAXON"}]},{"project":"pubmed-sentences-benchmark","denotations":[{"id":"S1","span":{"begin":0,"end":91},"obj":"Sentence"},{"id":"S2","span":{"begin":92,"end":173},"obj":"Sentence"},{"id":"S3","span":{"begin":174,"end":341},"obj":"Sentence"},{"id":"S4","span":{"begin":342,"end":642},"obj":"Sentence"},{"id":"S5","span":{"begin":643,"end":764},"obj":"Sentence"},{"id":"S6","span":{"begin":765,"end":919},"obj":"Sentence"},{"id":"S7","span":{"begin":920,"end":1076},"obj":"Sentence"},{"id":"S8","span":{"begin":1077,"end":1260},"obj":"Sentence"},{"id":"S9","span":{"begin":1261,"end":1379},"obj":"Sentence"},{"id":"S10","span":{"begin":1380,"end":1746},"obj":"Sentence"}],"attributes":[{"subj":"S1","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S2","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S3","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S4","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S5","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S6","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S7","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S8","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S9","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S10","pred":"source","obj":"pubmed-sentences-benchmark"}]},{"project":"GENIAcorpus","denotations":[{"id":"T1","span":{"begin":14,"end":27},"obj":"protein_complex"},{"id":"T2","span":{"begin":35,"end":59},"obj":"other_name"},{"id":"T3","span":{"begin":63,"end":90},"obj":"cell_type"},{"id":"T4","span":{"begin":96,"end":111},"obj":"protein_complex"},{"id":"T5","span":{"begin":111,"end":124},"obj":"protein_complex"},{"id":"T6","span":{"begin":152,"end":172},"obj":"other_name"},{"id":"T7","span":{"begin":229,"end":244},"obj":"protein_complex"},{"id":"T8","span":{"begin":244,"end":257},"obj":"protein_complex"},{"id":"T9","span":{"begin":261,"end":288},"obj":"cell_type"},{"id":"T10","span":{"begin":309,"end":340},"obj":"other_organic_compound"},{"id":"T11","span":{"begin":409,"end":422},"obj":"cell_type"},{"id":"T12","span":{"begin":424,"end":428},"obj":"protein_molecule"},{"id":"T13","span":{"begin":433,"end":436},"obj":"protein_molecule"},{"id":"T14","span":{"begin":458,"end":474},"obj":"protein_complex"},{"id":"T15","span":{"begin":507,"end":536},"obj":"other_name"},{"id":"T16","span":{"begin":585,"end":587},"obj":"other_name"},{"id":"T17","span":{"begin":599,"end":616},"obj":"other_name"},{"id":"T18","span":{"begin":634,"end":641},"obj":"other_name"},{"id":"T19","span":{"begin":661,"end":678},"obj":"protein_complex"},{"id":"T20","span":{"begin":699,"end":728},"obj":"cell_type"},{"id":"T21","span":{"begin":745,"end":748},"obj":"protein_molecule"},{"id":"T22","span":{"begin":750,"end":754},"obj":"protein_molecule"},{"id":"T23","span":{"begin":760,"end":763},"obj":"protein_molecule"},{"id":"T24","span":{"begin":831,"end":833},"obj":"other_name"},{"id":"T25","span":{"begin":837,"end":838},"obj":"other_name"},{"id":"T26","span":{"begin":858,"end":861},"obj":"protein_molecule"},{"id":"T27","span":{"begin":865,"end":868},"obj":"protein_molecule"},{"id":"T28","span":{"begin":996,"end":1010},"obj":"protein_family_or_group"},{"id":"T29","span":{"begin":1012,"end":1015},"obj":"protein_molecule"},{"id":"T30","span":{"begin":1020,"end":1024},"obj":"protein_molecule"},{"id":"T31","span":{"begin":1029,"end":1042},"obj":"cell_type"},{"id":"T32","span":{"begin":1059,"end":1061},"obj":"other_name"},{"id":"T33","span":{"begin":1073,"end":1075},"obj":"other_name"},{"id":"T34","span":{"begin":1123,"end":1140},"obj":"other_name"},{"id":"T35","span":{"begin":1192,"end":1214},"obj":"protein_family_or_group"},{"id":"T36","span":{"begin":1224,"end":1259},"obj":"protein_family_or_group"},{"id":"T37","span":{"begin":1305,"end":1327},"obj":"other_name"},{"id":"T38","span":{"begin":1399,"end":1419},"obj":"other_name"},{"id":"T39","span":{"begin":1441,"end":1458},"obj":"other_name"},{"id":"T40","span":{"begin":1462,"end":1465},"obj":"protein_molecule"},{"id":"T41","span":{"begin":1470,"end":1474},"obj":"protein_molecule"},{"id":"T42","span":{"begin":1509,"end":1533},"obj":"other_name"},{"id":"T43","span":{"begin":1561,"end":1575},"obj":"DNA_family_or_group"},{"id":"T44","span":{"begin":1605,"end":1614},"obj":"DNA_domain_or_region"},{"id":"T45","span":{"begin":1662,"end":1665},"obj":"protein_molecule"},{"id":"T46","span":{"begin":1718,"end":1728},"obj":"other_name"},{"id":"T47","span":{"begin":1732,"end":1745},"obj":"other_name"}],"attributes":[{"subj":"T1","pred":"source","obj":"GENIAcorpus"},{"subj":"T2","pred":"source","obj":"GENIAcorpus"},{"subj":"T3","pred":"source","obj":"GENIAcorpus"},{"subj":"T4","pred":"source","obj":"GENIAcorpus"},{"subj":"T5","pred":"source","obj":"GENIAcorpus"},{"subj":"T6","pred":"source","obj":"GENIAcorpus"},{"subj":"T7","pred":"source","obj":"GENIAcorpus"},{"subj":"T8","pred":"source","obj":"GENIAcorpus"},{"subj":"T9","pred":"source","obj":"GENIAcorpus"},{"subj":"T10","pred":"source","obj":"GENIAcorpus"},{"subj":"T11","pred":"source","obj":"GENIAcorpus"},{"subj":"T12","pred":"source","obj":"GENIAcorpus"},{"subj":"T13","pred":"source","obj":"GENIAcorpus"},{"subj":"T14","pred":"source","obj":"GENIAcorpus"},{"subj":"T15","pred":"source","obj":"GENIAcorpus"},{"subj":"T16","pred":"source","obj":"GENIAcorpus"},{"subj":"T17","pred":"source","obj":"GENIAcorpus"},{"subj":"T18","pred":"source","obj":"GENIAcorpus"},{"subj":"T19","pred":"source","obj":"GENIAcorpus"},{"subj":"T20","pred":"source","obj":"GENIAcorpus"},{"subj":"T21","pred":"source","obj":"GENIAcorpus"},{"subj":"T22","pred":"source","obj":"GENIAcorpus"},{"subj":"T23","pred":"source","obj":"GENIAcorpus"},{"subj":"T24","pred":"source","obj":"GENIAcorpus"},{"subj":"T25","pred":"source","obj":"GENIAcorpus"},{"subj":"T26","pred":"source","obj":"GENIAcorpus"},{"subj":"T27","pred":"source","obj":"GENIAcorpus"},{"subj":"T28","pred":"source","obj":"GENIAcorpus"},{"subj":"T29","pred":"source","obj":"GENIAcorpus"},{"subj":"T30","pred":"source","obj":"GENIAcorpus"},{"subj":"T31","pred":"source","obj":"GENIAcorpus"},{"subj":"T32","pred":"source","obj":"GENIAcorpus"},{"subj":"T33","pred":"source","obj":"GENIAcorpus"},{"subj":"T34","pred":"source","obj":"GENIAcorpus"},{"subj":"T35","pred":"source","obj":"GENIAcorpus"},{"subj":"T36","pred":"source","obj":"GENIAcorpus"},{"subj":"T37","pred":"source","obj":"GENIAcorpus"},{"subj":"T38","pred":"source","obj":"GENIAcorpus"},{"subj":"T39","pred":"source","obj":"GENIAcorpus"},{"subj":"T40","pred":"source","obj":"GENIAcorpus"},{"subj":"T41","pred":"source","obj":"GENIAcorpus"},{"subj":"T42","pred":"source","obj":"GENIAcorpus"},{"subj":"T43","pred":"source","obj":"GENIAcorpus"},{"subj":"T44","pred":"source","obj":"GENIAcorpus"},{"subj":"T45","pred":"source","obj":"GENIAcorpus"},{"subj":"T46","pred":"source","obj":"GENIAcorpus"},{"subj":"T47","pred":"source","obj":"GENIAcorpus"}]},{"project":"Anatomy-UBERON","denotations":[{"id":"T1","span":{"begin":77,"end":90},"obj":"Body_part"},{"id":"T2","span":{"begin":152,"end":162},"obj":"Body_part"},{"id":"T3","span":{"begin":275,"end":288},"obj":"Body_part"},{"id":"T4","span":{"begin":393,"end":404},"obj":"Body_part"},{"id":"T5","span":{"begin":409,"end":422},"obj":"Body_part"},{"id":"T6","span":{"begin":513,"end":525},"obj":"Body_part"},{"id":"T7","span":{"begin":526,"end":536},"obj":"Body_part"},{"id":"T8","span":{"begin":715,"end":728},"obj":"Body_part"},{"id":"T9","span":{"begin":908,"end":918},"obj":"Body_part"},{"id":"T10","span":{"begin":1029,"end":1042},"obj":"Body_part"},{"id":"T11","span":{"begin":1145,"end":1151},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_2000098"},{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CL_0000057"},{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_2000098"},{"id":"A8","pred":"uberon_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"A9","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/UBERON_2000098"},{"id":"A10","pred":"uberon_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_0013424"},{"subj":"T1","pred":"source","obj":"Anatomy-UBERON"},{"subj":"T2","pred":"source","obj":"Anatomy-UBERON"},{"subj":"T3","pred":"source","obj":"Anatomy-UBERON"},{"subj":"T4","pred":"source","obj":"Anatomy-UBERON"},{"subj":"T5","pred":"source","obj":"Anatomy-UBERON"},{"subj":"T6","pred":"source","obj":"Anatomy-UBERON"},{"subj":"T7","pred":"source","obj":"Anatomy-UBERON"},{"subj":"T8","pred":"source","obj":"Anatomy-UBERON"},{"subj":"T9","pred":"source","obj":"Anatomy-UBERON"},{"subj":"T10","pred":"source","obj":"Anatomy-UBERON"},{"subj":"T11","pred":"source","obj":"Anatomy-UBERON"}]},{"project":"CL-cell","denotations":[{"id":"T1","span":{"begin":77,"end":90},"obj":"Cell"},{"id":"T2","span":{"begin":275,"end":288},"obj":"Cell"},{"id":"T3","span":{"begin":393,"end":404},"obj":"Cell"},{"id":"T4","span":{"begin":409,"end":422},"obj":"Cell"},{"id":"T5","span":{"begin":513,"end":525},"obj":"Cell"},{"id":"T6","span":{"begin":515,"end":525},"obj":"Cell"},{"id":"T7","span":{"begin":715,"end":728},"obj":"Cell"},{"id":"T8","span":{"begin":1029,"end":1042},"obj":"Cell"}],"attributes":[{"id":"A1","pred":"cl_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CL:0000236"},{"id":"A2","pred":"cl_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CL:0000236"},{"id":"A3","pred":"cl_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CL:0000057"},{"id":"A4","pred":"cl_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CL:0000084"},{"id":"A5","pred":"cl_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CL:0000236"},{"id":"A6","pred":"cl_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CL:0000542"},{"id":"A7","pred":"cl_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CL:0000236"},{"id":"A8","pred":"cl_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CL:0000236"},{"subj":"T1","pred":"source","obj":"CL-cell"},{"subj":"T2","pred":"source","obj":"CL-cell"},{"subj":"T3","pred":"source","obj":"CL-cell"},{"subj":"T4","pred":"source","obj":"CL-cell"},{"subj":"T5","pred":"source","obj":"CL-cell"},{"subj":"T6","pred":"source","obj":"CL-cell"},{"subj":"T7","pred":"source","obj":"CL-cell"},{"subj":"T8","pred":"source","obj":"CL-cell"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"genia-medco-coref","color":"#93eca0","default":true},{"id":"jnlpba-st-training","color":"#ec93a0"},{"id":"sentences","color":"#93baec"},{"id":"NCBITAXON","color":"#d4ec93"},{"id":"pubmed-sentences-benchmark","color":"#ea93ec"},{"id":"GENIAcorpus","color":"#93ecd0"},{"id":"Anatomy-UBERON","color":"#ecb693"},{"id":"CL-cell","color":"#9c93ec"}]}]}}