PubMed:10207017
Annnotations
GGDB-2020
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 139-152 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
T2 | 367-380 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
T3 | 749-762 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
T4 | 1167-1180 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
T5 | 1406-1418 | https://acgg.asia/db/ggdb/info/gg059 | denotes | ST6GalNAc IV |
T6 | 1492-1505 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
T7 | 1507-1519 | https://acgg.asia/db/ggdb/info/gg059 | denotes | ST6GalNAc IV |
T8 | 1602-1615 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
ggdb-test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 139-152 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
T2 | 367-380 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
T3 | 749-762 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
T4 | 1167-1180 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
T5 | 1406-1418 | https://acgg.asia/db/ggdb/info/gg059 | denotes | ST6GalNAc IV |
T6 | 1492-1505 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
T7 | 1507-1519 | https://acgg.asia/db/ggdb/info/gg059 | denotes | ST6GalNAc IV |
T8 | 1602-1615 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
GlyCosmos6-Glycan-Motif-Image
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 884-888 | Glycan_Motif | denotes | GM1b | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G03277YI |
T2 | 1297-1308 | Glycan_Motif | denotes | sialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-160 | Sentence | denotes | Molecular cloning and functional expression of two members of mouse NeuAcalpha2,3Galbeta1,3GalNAc GalNAcalpha2,6-sialyltransferase family, ST6GalNAc III and IV. |
T2 | 161-301 | Sentence | denotes | Two cDNA clones encoding NeuAcalpha2,3Galbeta1,3GalNAc GalNAcalpha2, 6-sialyltransferase have been isolated from mouse brain cDNA libraries. |
T3 | 302-587 | Sentence | denotes | One of the cDNA clones is a homologue of previously reported rat ST6GalNAc III according to the amino acid sequence identity (94.4%) and the substrate specificity of the expressed recombinant enzyme, while the other cDNA clone includes an open reading frame coding for 302 amino acids. |
T4 | 588-771 | Sentence | denotes | The deduced amino acid sequence is not identical to those of other cloned mouse sialyltransferases, although it shows the highest sequence similarity with mouse ST6GalNAc III (43.0%). |
T5 | 772-1018 | Sentence | denotes | The expressed soluble recombinant enzyme exhibited activity toward NeuAcalpha2, 3Galbeta1, 3GalNAc, fetuin, and GM1b, while no significant activity was detected toward Galbeta1,3GalNAc or asialofetuin, or the other glycoprotein substrates tested. |
T6 | 1019-1181 | Sentence | denotes | The sialidase sensitivity of the 14C-sialylated residue of fetuin, which was sialylated by this enzyme with CMP-[14C]NeuAc, was the same as that of ST6GalNAc III. |
T7 | 1182-1419 | Sentence | denotes | These results indicate that the expressed enzyme is a new type of GalNAcalpha2,6-sialyltransferase, which requires sialic acid residues linked to Galbeta1,3GalNAc residues for its activity; therefore, we designated it mouse ST6GalNAc IV. |
T8 | 1420-1553 | Sentence | denotes | Although the substrate specificity of this enzyme is similar to that of ST6GalNAc III, ST6GalNAc IV prefers O-glycans to glycolipids. |
T9 | 1554-1616 | Sentence | denotes | Glycolipids, however, are better substrates for ST6GalNAc III. |
GlyCosmos6-Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 884-888 | https://glytoucan.org/Structures/Glycans/G03277YI | denotes | GM1b |
T2 | 1297-1308 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
Glycosmos6-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 884-888 | http://www.glycoepitope.jp/epitopes/EP0048 | denotes | GM1b |
Glycosmos6-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 280-285 | http://purl.obolibrary.org/obo/MAT_0000098 | denotes | brain |
glycogenes
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-GlycoGenes20190927-B_T1 | 139-152 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
PD-GlycoGenes20190927-B_T2 | 367-380 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
PD-GlycoGenes20190927-B_T3 | 749-762 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
PD-GlycoGenes20190927-B_T4 | 1167-1180 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
PD-GlycoGenes20190927-B_T5 | 1386-1396 | url | denotes | designated |
PD-GlycoGenes20190927-B_T6 | 1406-1418 | https://acgg.asia/db/ggdb/info/gg059 | denotes | ST6GalNAc IV |
PD-GlycoGenes20190927-B_T7 | 1492-1505 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
PD-GlycoGenes20190927-B_T8 | 1507-1519 | https://acgg.asia/db/ggdb/info/gg059 | denotes | ST6GalNAc IV |
PD-GlycoGenes20190927-B_T9 | 1602-1615 | https://acgg.asia/db/ggdb/info/gg058 | denotes | ST6GalNAc III |
Anatomy-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 280-285 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
Glycan-GlyCosmos
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 884-888 | Glycan | denotes | GM1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G03277YI |
T2 | 1136-1141 | Glycan | denotes | NeuAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
GlyCosmos-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 884-888 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1b | http://www.glycoepitope.jp/epitopes/EP0048 |
GlyCosmos15-NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 62-67 | OrganismTaxon | denotes | mouse | 10088|10090 |
T3 | 274-279 | OrganismTaxon | denotes | mouse | 10088|10090 |
T5 | 363-366 | OrganismTaxon | denotes | rat | 10114|10116 |
T7 | 662-667 | OrganismTaxon | denotes | mouse | 10088|10090 |
T9 | 743-748 | OrganismTaxon | denotes | mouse | 10088|10090 |
T11 | 1400-1405 | OrganismTaxon | denotes | mouse | 10088|10090 |
GlyCosmos15-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 280-285 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
GlyCosmos15-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 280-285 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-160 | Sentence | denotes | Molecular cloning and functional expression of two members of mouse NeuAcalpha2,3Galbeta1,3GalNAc GalNAcalpha2,6-sialyltransferase family, ST6GalNAc III and IV. |
T2 | 161-301 | Sentence | denotes | Two cDNA clones encoding NeuAcalpha2,3Galbeta1,3GalNAc GalNAcalpha2, 6-sialyltransferase have been isolated from mouse brain cDNA libraries. |
T3 | 302-587 | Sentence | denotes | One of the cDNA clones is a homologue of previously reported rat ST6GalNAc III according to the amino acid sequence identity (94.4%) and the substrate specificity of the expressed recombinant enzyme, while the other cDNA clone includes an open reading frame coding for 302 amino acids. |
T4 | 588-771 | Sentence | denotes | The deduced amino acid sequence is not identical to those of other cloned mouse sialyltransferases, although it shows the highest sequence similarity with mouse ST6GalNAc III (43.0%). |
T5 | 772-1018 | Sentence | denotes | The expressed soluble recombinant enzyme exhibited activity toward NeuAcalpha2, 3Galbeta1, 3GalNAc, fetuin, and GM1b, while no significant activity was detected toward Galbeta1,3GalNAc or asialofetuin, or the other glycoprotein substrates tested. |
T6 | 1019-1181 | Sentence | denotes | The sialidase sensitivity of the 14C-sialylated residue of fetuin, which was sialylated by this enzyme with CMP-[14C]NeuAc, was the same as that of ST6GalNAc III. |
T7 | 1182-1419 | Sentence | denotes | These results indicate that the expressed enzyme is a new type of GalNAcalpha2,6-sialyltransferase, which requires sialic acid residues linked to Galbeta1,3GalNAc residues for its activity; therefore, we designated it mouse ST6GalNAc IV. |
T8 | 1420-1553 | Sentence | denotes | Although the substrate specificity of this enzyme is similar to that of ST6GalNAc III, ST6GalNAc IV prefers O-glycans to glycolipids. |
T9 | 1554-1616 | Sentence | denotes | Glycolipids, however, are better substrates for ST6GalNAc III. |
GlyCosmos15-Sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-160 | Sentence | denotes | Molecular cloning and functional expression of two members of mouse NeuAcalpha2,3Galbeta1,3GalNAc GalNAcalpha2,6-sialyltransferase family, ST6GalNAc III and IV. |
T2 | 161-301 | Sentence | denotes | Two cDNA clones encoding NeuAcalpha2,3Galbeta1,3GalNAc GalNAcalpha2, 6-sialyltransferase have been isolated from mouse brain cDNA libraries. |
T3 | 302-587 | Sentence | denotes | One of the cDNA clones is a homologue of previously reported rat ST6GalNAc III according to the amino acid sequence identity (94.4%) and the substrate specificity of the expressed recombinant enzyme, while the other cDNA clone includes an open reading frame coding for 302 amino acids. |
T4 | 588-771 | Sentence | denotes | The deduced amino acid sequence is not identical to those of other cloned mouse sialyltransferases, although it shows the highest sequence similarity with mouse ST6GalNAc III (43.0%). |
T5 | 772-1018 | Sentence | denotes | The expressed soluble recombinant enzyme exhibited activity toward NeuAcalpha2, 3Galbeta1, 3GalNAc, fetuin, and GM1b, while no significant activity was detected toward Galbeta1,3GalNAc or asialofetuin, or the other glycoprotein substrates tested. |
T6 | 1019-1181 | Sentence | denotes | The sialidase sensitivity of the 14C-sialylated residue of fetuin, which was sialylated by this enzyme with CMP-[14C]NeuAc, was the same as that of ST6GalNAc III. |
T7 | 1182-1419 | Sentence | denotes | These results indicate that the expressed enzyme is a new type of GalNAcalpha2,6-sialyltransferase, which requires sialic acid residues linked to Galbeta1,3GalNAc residues for its activity; therefore, we designated it mouse ST6GalNAc IV. |
T8 | 1420-1553 | Sentence | denotes | Although the substrate specificity of this enzyme is similar to that of ST6GalNAc III, ST6GalNAc IV prefers O-glycans to glycolipids. |
T9 | 1554-1616 | Sentence | denotes | Glycolipids, however, are better substrates for ST6GalNAc III. |
GlyCosmos15-Glycan
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 884-888 | Glycan | denotes | GM1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G03277YI |
T2 | 1136-1141 | Glycan | denotes | NeuAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR |
GlyCosmos15-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 884-888 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1b | http://www.glycoepitope.jp/epitopes/EP0048 |
NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 62-67 | OrganismTaxon | denotes | mouse | 10088|10090 |
T3 | 274-279 | OrganismTaxon | denotes | mouse | 10088|10090 |
T5 | 363-366 | OrganismTaxon | denotes | rat | 10114|10116 |
T7 | 662-667 | OrganismTaxon | denotes | mouse | 10088|10090 |
T9 | 743-748 | OrganismTaxon | denotes | mouse | 10088|10090 |
T11 | 1400-1405 | OrganismTaxon | denotes | mouse | 10088|10090 |
Anatomy-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 280-285 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |