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PubMed:10051632 JSONTXT

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PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 173-191 DiseaseOrPhenotypicFeature denotes autoimmune disease 0007179
T2 466-469 DiseaseOrPhenotypicFeature denotes can 0012833
T3 1394-1397 DiseaseOrPhenotypicFeature denotes can 0012833
T4 1612-1630 DiseaseOrPhenotypicFeature denotes autoimmune disease 0007179

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 75-134 cell_type denotes human class I-restricted cytotoxic T lymphocyte clonotypes:
T2 213-242 cell_type denotes CD8(+) cytotoxic T lymphocyte
T3 317-359 protein denotes Epstein-Barr virus immediate-early antigen
T4 361-366 protein denotes BZLF1
T5 398-430 protein denotes T cell receptor (TCR) repertoire
T6 603-626 protein denotes serine/threonine kinase
T7 671-723 protein denotes Staphylococcus aureus replication initiation protein
T8 730-740 cell_line denotes CTL clones
T9 837-840 protein denotes TCR
T10 856-866 cell_line denotes CTL clones
T11 1008-1011 protein denotes TCR
T12 1224-1235 cell_type denotes memory CTLs
T13 1571-1588 cell_line denotes I-restricted CTLs

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 173-191 NP denotes autoimmune disease
C2 261-290 NP denotes the HLA-B8-restricted peptide
C3 292-300 NP denotes RAKFKQLL
C4 313-359 NP denotes the Epstein-Barr virus immediate-early antigen
C5 361-366 NP denotes BZLF1
C6 730-740 NP denotes CTL clones
C7 741-745 NP denotes that
C8 852-866 NP denotes The CTL clones
C9 867-871 NP denotes that
C10 938-944 NP denotes clones
C11 945-949 NP denotes that
C12 1612-1630 NP denotes autoimmune disease
R1 C3 C2 coref-appos RAKFKQLL,the HLA-B8-restricted peptide
R2 C5 C4 coref-appos BZLF1,the Epstein-Barr virus immediate-early antigen
R3 C7 C6 coref-relat that,CTL clones
R4 C9 C8 coref-relat that,The CTL clones
R5 C11 C10 coref-relat that,clones
R6 C12 C1 coref-ident autoimmune disease,autoimmune disease

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-192 Sentence denotes Crossreactive recognition of viral, self, and bacterial peptide ligands by human class I-restricted cytotoxic T lymphocyte clonotypes: implications for molecular mimicry in autoimmune disease.
S2 193-431 Sentence denotes The immunodominant, CD8(+) cytotoxic T lymphocyte (CTL) response to the HLA-B8-restricted peptide, RAKFKQLL, located in the Epstein-Barr virus immediate-early antigen, BZLF1, is characterized by a diverse T cell receptor (TCR) repertoire.
S3 432-724 Sentence denotes Here, we show that this diversity can be partitioned on the basis of crossreactive cytotoxicity patterns involving the recognition of a self peptide-RSKFRQIV-located in a serine/threonine kinase and a bacterial peptide-RRKYKQII-located in Staphylococcus aureus replication initiation protein.
S4 725-851 Sentence denotes Thus CTL clones that recognized the viral, self, and bacterial peptides expressed a highly restricted alphabeta TCR phenotype.
S5 852-1020 Sentence denotes The CTL clones that recognized viral and self peptides were more oligoclonal, whereas clones that strictly recognized the viral peptide displayed a diverse TCR profile.
S6 1021-1316 Sentence denotes Interestingly, the self and bacterial peptides equally were substantially less effective than the cognate viral peptide in sensitizing target cell lysis, and also resulted only in a weak reactivation of memory CTLs in limiting dilution assays, whereas the cognate peptide was highly immunogenic.
S7 1317-1631 Sentence denotes The described crossreactions show that human antiviral, CD8(+) CTL responses can be shaped by peptide ligands derived from autoantigens and environmental bacterial antigens, thereby providing a firm structural basis for molecular mimicry involving class I-restricted CTLs in the pathogenesis of autoimmune disease.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-25 other_name denotes Crossreactive recognition
T2 46-71 peptide denotes bacterial peptide ligands
T3 75-134 cell_type denotes human class I-restricted cytotoxic T lymphocyte clonotypes:
T4 152-169 other_name denotes molecular mimicry
T5 173-191 other_name denotes autoimmune disease
T6 197-212 other_name denotes immunodominant,
T7 213-242 cell_type denotes CD8(+) cytotoxic T lymphocyte
T8 265-290 peptide denotes HLA-B8-restricted peptide
T9 292-300 peptide denotes RAKFKQLL
T10 317-359 protein_molecule denotes Epstein-Barr virus immediate-early antigen
T11 361-366 protein_molecule denotes BZLF1
T12 398-430 protein_family_or_group denotes T cell receptor (TCR) repertoire
T13 501-536 other_name denotes crossreactive cytotoxicity patterns
T14 568-580 peptide denotes self peptide
T15 581-589 peptide denotes RSKFRQIV
T16 603-609 amino_acid_monomer denotes serine
T17 609-619 amino_acid_monomer denotes /threonine
T18 633-650 peptide denotes bacterial peptide
T19 651-659 peptide denotes RRKYKQII
T20 671-692 mono_cell denotes Staphylococcus aureus
T21 730-740 cell_line denotes CTL clones
T22 827-836 other_name denotes alphabeta
T23 837-840 protein_family_or_group denotes TCR
T24 856-866 cell_line denotes CTL clones
T25 974-987 peptide denotes viral peptide
T26 1000-1007 other_name denotes diverse
T27 1008-1011 protein_family_or_group denotes TCR
T28 1127-1140 peptide denotes viral peptide
T29 1224-1235 cell_type denotes memory CTLs
T30 1239-1263 other_name denotes limiting dilution assays
T31 1277-1292 peptide denotes cognate peptide
T32 1362-1393 other_name denotes antiviral, CD8(+) CTL responses
T33 1481-1489 other_organic_compound denotes antigens
T34 1537-1554 other_name denotes molecular mimicry
T35 1571-1588 cell_line denotes I-restricted CTLs
T36 1612-1630 other_name denotes autoimmune disease

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 1612-1630 HP_0002960 denotes autoimmune disease
T2 1612-1622 HP_0002960 denotes autoimmune