PMC:8275828 / 6141-7155 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/8275828","sourcedb":"PMC","sourceid":"8275828","source_url":"https://www.ncbi.nlm.nih.gov/pmc/8275828","text":"Subject Recruitment and Brain Collection\nThe design of GCS, objectives, protocols of subject recruitment, and brain collection have been previously described in detail (34, 35). Briefly, the GCS was a population-based study conducted in 44 counties in northern Georgia. The GCS was primarily designed to identify biological, psychological, and social factors contributing to survivorship and successful aging. Brain tissues from frontal (FC) and temporal cortices (TC) were collected from 47 subjects who were a subset of centenarians enrolled in the phase III of the GCS (2001–2007) and gave consent to donate brain tissue upon death. After tissue collection, all samples were coded and stored at −80°C until the measures of nutrient concentration. All protocols were performed with an approval from the University of Georgia Institutional Review Board. Separate approval for using de-identified data for the present analyses was obtained from the Tufts University/Tufts Medical Center Institutional Review Board.","divisions":[{"label":"title","span":{"begin":0,"end":40}}],"tracks":[{"project":"TEST0","denotations":[{"id":"34268331-128-134-887357","span":{"begin":169,"end":171},"obj":"[\"21852888\"]"},{"id":"34268331-132-138-887358","span":{"begin":173,"end":175},"obj":"[\"24013849\"]"}],"attributes":[{"subj":"34268331-128-134-887357","pred":"source","obj":"TEST0"},{"subj":"34268331-132-138-887358","pred":"source","obj":"TEST0"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"TEST0","color":"#d2ec93","default":true}]}]}}