Id |
Subject |
Object |
Predicate |
Lexical cue |
T40 |
0-66 |
Sentence |
denotes |
G6PD status is extremely important in modulating the level of ROS. |
T41 |
67-200 |
Sentence |
denotes |
On the one hand, G6PD maintains redox homeostasis by keeping cytotoxic ROS at proper levels because high levels of ROS are cytotoxic. |
T42 |
201-479 |
Sentence |
denotes |
For example, 120-150 µM of hydrogen peroxide (H2O2) leads to temporary growth arrest, while repeated encounters of the treatment or an increase in concentration by 2-fold (250–450 µM) of H2O2 causes the cells to permanently undergo growth arrest or enter into a senescent state. |
T43 |
480-554 |
Sentence |
denotes |
At even higher concentrations (0.5–1 mM) of H2O2, cells undergo apoptosis. |
T44 |
555-649 |
Sentence |
denotes |
Cells exhibit necrosis when challenged with even higher concentrations (5-10 mM) of H2O2 [18]. |
T45 |
650-823 |
Sentence |
denotes |
On the other hand, different low levels of ROS can induce a wide spectrum of cellular responses such as with 3–15 µM of H2O2, which can stimulate mitogenic cell growth [19]. |
T46 |
824-922 |
Sentence |
denotes |
ROS at sub-micromolar ranges often serves as messengers for regulating cellular processes [20,21]. |