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PMC:7799378 / 4367-5289 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
176 0-4 Gene denotes G6PD Gene:2539
177 84-88 Gene denotes G6PD Gene:2539
178 62-65 Chemical denotes ROS MESH:D017382
179 138-141 Chemical denotes ROS MESH:D017382
180 182-185 Chemical denotes ROS MESH:D017382
181 228-245 Chemical denotes hydrogen peroxide MESH:D006861
182 247-251 Chemical denotes H2O2 MESH:D006861
183 388-392 Chemical denotes H2O2 MESH:D006861
184 524-528 Chemical denotes H2O2 MESH:D006861
185 639-643 Chemical denotes H2O2 MESH:D006861
186 693-696 Chemical denotes ROS MESH:D017382
187 770-774 Chemical denotes H2O2 MESH:D006861
188 824-827 Chemical denotes ROS MESH:D017382
189 272-285 Disease denotes growth arrest MESH:D006323
190 433-446 Disease denotes growth arrest MESH:D006323
191 569-577 Disease denotes necrosis MESH:D009336

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T40 0-66 Sentence denotes G6PD status is extremely important in modulating the level of ROS.
T41 67-200 Sentence denotes On the one hand, G6PD maintains redox homeostasis by keeping cytotoxic ROS at proper levels because high levels of ROS are cytotoxic.
T42 201-479 Sentence denotes For example, 120-150 µM of hydrogen peroxide (H2O2) leads to temporary growth arrest, while repeated encounters of the treatment or an increase in concentration by 2-fold (250–450 µM) of H2O2 causes the cells to permanently undergo growth arrest or enter into a senescent state.
T43 480-554 Sentence denotes At even higher concentrations (0.5–1 mM) of H2O2, cells undergo apoptosis.
T44 555-649 Sentence denotes Cells exhibit necrosis when challenged with even higher concentrations (5-10 mM) of H2O2 [18].
T45 650-823 Sentence denotes On the other hand, different low levels of ROS can induce a wide spectrum of cellular responses such as with 3–15 µM of H2O2, which can stimulate mitogenic cell growth [19].
T46 824-922 Sentence denotes ROS at sub-micromolar ranges often serves as messengers for regulating cellular processes [20,21].