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PMC:7796072 / 4327-5678 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
104 16-19 Gene denotes HbE Gene:3046
105 24-42 Disease denotes Thalassemia Traits MESH:D013789
121 982-985 Gene denotes HbE Gene:3046
122 1196-1199 Gene denotes HbE Gene:3046
123 903-906 Gene denotes HbE Gene:3046
124 1298-1301 Gene denotes Sri Gene:6717
125 175-181 Species denotes people Tax:9606
126 61-68 Disease denotes SE Asia MESH:D008133
127 223-230 Disease denotes SE Asia MESH:D008133
128 381-388 Disease denotes SE Asia MESH:D008133
129 421-432 Disease denotes thalassemia MESH:D013789
130 518-539 Disease denotes thalassemic syndromes MESH:D061325
131 552-564 Disease denotes thalassemias MESH:D013789
132 719-733 Disease denotes β-thalassemias MESH:D017086
133 912-941 Disease denotes thalassemic symbol of SE Asia MESH:D013789
134 1158-1165 Disease denotes SE Asia MESH:D008133
135 1167-1178 Disease denotes thalassemia MESH:D013789

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T33 0-60 Sentence denotes Epidemiology of HbE and Thalassemia Traits in Southeast Asia
T34 61-222 Sentence denotes SE Asia is the third most populous region in the world [11], encompassing 10 countries with more than 650 million people inhabiting an area over 4.5 million km2.
T35 223-330 Sentence denotes SE Asia is a genetic cauldron of different ethnicities descending from diverse and complex origins [11,12].
T36 331-545 Sentence denotes Shaped by local malarial environmental pressures, SE Asia’s common genetic denominator is thalassemia, presenting with over 60 different allelic variants, but mainly dominated by 4 major thalassemic syndromes [13].
T37 546-714 Sentence denotes The α-thalassemias, with a gene prevalence approaching 40% in northern Thailand and Laos, are considerably less common in Malaysia and the Philippines (around 5%) [13].
T38 715-815 Sentence denotes The β-thalassemias showing local variations in genetic prevalence account for up to 9% of all cases.
T39 816-902 Sentence denotes Thirdly, Hb Constant Spring [CS] is also seen, with gene frequencies of up to 8% [13].
T40 903-981 Sentence denotes HbE, the thalassemic symbol of SE Asia, is increasingly encountered worldwide.
T41 982-1146 Sentence denotes HbE gene prevalence may reach up to 70% locally in northeastern Thailand and and up to 62% at the triple border region between Thailand, Cambodia, and Laos [13–15].
T42 1147-1351 Sentence denotes Apart from SE Asia, thalassemia genes (including HbE) are also present with diminishing gene frequency in Yunnan, Nepal, Northeastern India, Pakistan, Sri Lanka, Bangladesh, Hong Kong, and Taiwan [13–24].