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PMC:7796072 / 12841-13849 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
359 323-326 Gene denotes ABO Gene:28
360 473-488 Gene denotes ABO blood group Gene:28
361 911-914 Gene denotes HbE Gene:3046
362 46-54 Disease denotes COVID-19 MESH:C000657245
363 158-169 Disease denotes thalassemia MESH:D013789
364 222-229 Disease denotes malaria MESH:D008288
365 386-394 Disease denotes COVID-19 MESH:C000657245
366 395-404 Disease denotes infection MESH:D007239
367 585-593 Disease denotes COVID-19 MESH:C000657245
368 594-603 Disease denotes infection MESH:D007239
369 674-681 Disease denotes malaria MESH:D008288

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T83 0-180 Sentence denotes The hypothesized conferred protection against COVID-19 could also derive from local SE Asian HLA-class allotypes, possibly in linkage disequilibrium with the thalassemia mutations.
T84 181-351 Sentence denotes Protection from and resistance to severe malaria has been described in association with HLA antigens in the African continent [54,55] and the ABO blood group system [56].
T85 352-635 Sentence denotes However, no HLA associations with COVID-19 infection have been noted in a recent report [57] but an association with the ABO blood group system was confirmed, with bearers of the blood group A phenotype showing an increased risk for COVID-19 infection compared to blood group O [58].
T86 636-794 Sentence denotes The O phenotype appears protective to malaria [56] and its worldwide distribution seems to have been shaped by the parasite’s selective genetic pressure [56].
T87 795-1008 Sentence denotes The frequency of the O blood group in Thailand is 40.5% [59] and its relatively high prevalence along with the high HbE heterozygote frequency could further potentiate the hypothesized antiviral protective effect.