PMC:7795966 / 3822-4443
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
154 | 539-544 | Gene | denotes | MetHb | Gene:3048 |
155 | 0-5 | Gene | denotes | MetHb | Gene:3048 |
156 | 157-190 | Chemical | denotes | nicotinamide adenine dinucleotide | MESH:D009243 |
157 | 192-196 | Chemical | denotes | NADH | MESH:D009243 |
158 | 296-305 | Chemical | denotes | ascorbate | MESH:D001205 |
159 | 310-321 | Chemical | denotes | glutathione | MESH:D005978 |
160 | 355-370 | Chemical | denotes | carbon monoxide | MESH:D002248 |
161 | 372-374 | Chemical | denotes | CO | MESH:D002248 |
162 | 386-388 | Chemical | denotes | CO | MESH:D002248 |
163 | 398-402 | Chemical | denotes | heme | MESH:D006418 |
164 | 433-435 | Chemical | denotes | O2 | MESH:D010100 |
165 | 475-477 | Chemical | denotes | O2 | MESH:D010100 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T25 | 0-327 | Sentence | denotes | MetHb is continuously produced under physiological conditions in a limited amount due to auto-oxidation, but it is rapidly converted back to Hb primarily by nicotinamide adenine dinucleotide (NADH)-dependent cytochrome-b5 reductase (also known as MetHb reductase) and to a limited degree also by ascorbate and glutathione [13]. |
T26 | 328-436 | Sentence | denotes | COHb is formed when Hb and carbon monoxide (CO) interact; CO binds to heme molecules 240 times more than O2. |
T27 | 437-501 | Sentence | denotes | The resulting COHb limits the blood’s O2-carrying capacity [14]. |
T28 | 502-621 | Sentence | denotes | In healthy, non-smoking individuals, MetHb is in the range of 0.67 ± 0.33% [15] and COHb in the range of 0.5–1.5% [16]. |